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16 relations: Cluster of differentiation, Endothelium, Gene, High endothelial venules, Immunoglobulin domain, Integrin, Lymphatic system, Lymphocyte, Lymphocyte homing receptor, Paracellular transport, PARD3, Protein, Protein–protein interaction, Tight junction, VLA-4, White blood cell.
Cluster of differentiation
The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.
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Endothelium
Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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High endothelial venules
High endothelial venules (HEV) are specialized post-capillary venous swellings characterized by plump endothelial cells as opposed to the usual thinner endothelial cells found in regular venules.
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Immunoglobulin domain
The immunoglobulin domain is a type of protein domain that consists of a 2-layer sandwich of 7-9 antiparallel β-strands arranged in two β-sheets with a Greek key topology, consisting of about 125 amino acids.
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Integrin
Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.
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Lymphatic system
The lymphatic system is part of the vascular system and an important part of the immune system, comprising a network of lymphatic vessels that carry a clear fluid called lymph (from Latin, lympha meaning "water") directionally towards the heart.
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Lymphocyte
A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.
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Lymphocyte homing receptor
Lymphocyte homing receptors are cell adhesion molecules expressed on lymphocyte cell membranes that recognize addressins on target tissues.
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Paracellular transport
Paracellular transport refers to the transfer of substances across an epithelium by passing through the intercellular space between the cells.
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PARD3
Partitioning defective 3 homolog is a protein that in humans is encoded by the PARD3 gene.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Tight junction
Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens) are multiprotein junctional complex whose general function is to prevent leakage of transported solutes and water and seals the paracellular pathway.
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VLA-4
Integrin α4β1 (Very Late Antigen-4) is an integrin dimer.
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White blood cell
White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
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CD322, JAM2 (gene), Junctional adhesion molecule.
