6 relations: Anti-inflammatory, Histamine H4 receptor, Itch, Johnson & Johnson Pharmaceutical Research and Development, Receptor antagonist, VUF-6002.
Anti-inflammatory
Anti-inflammatory, or antiinflammatory, refers to the property of a substance or treatment that reduces inflammation or swelling.
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Histamine H4 receptor
The histamine H4 receptor is, like the other three histamine receptors, a member of the G protein-coupled receptor superfamily.
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Itch
Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.
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Johnson & Johnson Pharmaceutical Research and Development
Johnson & Johnson Pharmaceutical Research and Development (J&JPRD) is a subsidiary of Johnson & Johnson that is responsible for discovering and developing pharmaceutical drugs.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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VUF-6002
VUF-6002 (JNJ-10191584) is a drug which acts as a potent and selective antagonist at the histamine H4 receptor.
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