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54 relations: Agonist, AM-2201, Analgesic, APICA (synthetic cannabinoid drug), BIM-018, British Journal of Pharmacology, Cannabinoid, Cannabinoid receptor, Cannabis use disorder, Clemson University, Convulsion, CP 47,497, Drug metabolism, EC50, Endocannabinoid system, Epileptic seizure, European Monitoring Centre for Drugs and Drug Addiction, Food and Drug Administration Safety and Innovation Act, FUBIMINA, GABA receptor, Gas chromatography–mass spectrometry, Glucuronide, HU-210, John W. Huffman, JWH-015, JWH-019, JWH-073, JWH-081, JWH-122, JWH-200, JWH-203, JWH-210, JWH-250, JWH-302, JWH-398, Khat, Liquid chromatography–mass spectrometry, List of JWH cannabinoids, Ministry of Health, Labour and Welfare, Naphthoylindole, Partial agonist, PB-22, QUCHIC, RCS-4, Salvia divinorum, SDB-005, Standard for the Uniform Scheduling of Medicines and Poisons, Substituted phenethylamine, Synthetic cannabinoids, Tetrahydrocannabinol, ..., THJ-018, THJ-2201, 2C-B, 2C-P. Expand index (4 more) »
Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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AM-2201
AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor.
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Analgesic
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.
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APICA (synthetic cannabinoid drug)
APICA (2NE1, SDB-001, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide) is an indole based drug that acts as a potent agonist for the cannabinoid receptors.
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BIM-018
BIM-018 is a synthetic cannabinoid that is the benzimidazole analog of JWH-018.
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British Journal of Pharmacology
The British Journal of Pharmacology is a biweekly peer-reviewed medical journal covering all aspects of experimental pharmacology.
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Cannabinoid
A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain.
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Cannabinoid receptor
Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory.
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Cannabis use disorder
Cannabis use disorder (CUD) (also known as cannabis or marijuana addiction) is defined in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and ICD-10 published by World Health Organization as the continued use of cannabis despite clinically significant impairment, ranging from mild to severe.
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Clemson University
Clemson University is an American public, coeducational, land-grant and sea-grant research university in Clemson, South Carolina.
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Convulsion
A convulsion is a medical condition where body muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body.
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CP 47,497
CP 47,497 or (C7)-CP 47,497 is a cannabinoid receptor agonist drug, developed by Pfizer in the 1980s.
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Drug metabolism
Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems.
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EC50
Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.
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Endocannabinoid system
The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the mammalian central nervous system (including the brain) and peripheral nervous system.
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Epileptic seizure
An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
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European Monitoring Centre for Drugs and Drug Addiction
The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) is an agency of the European Union located in Lisbon, Portugal.
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Food and Drug Administration Safety and Innovation Act
The Food and Drug Administration Safety and Innovation Act of 2012 (FDASIA) is a piece of American regulatory legislation signed into law on July 9, 2012.
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FUBIMINA
FUBIMINA (also known as BIM-2201, BZ-2201 and FTHJ) is a synthetic cannabinoid that is the benzimidazole analog of AM-2201 and has been used as an active ingredient in synthetic cannabis products.
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GABA receptor
The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system.
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Gas chromatography–mass spectrometry
Gas chromatography–mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample.
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Glucuronide
A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond.
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HU-210
HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol by a group led by Professor Raphael Mechoulam at the Hebrew University.
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John W. Huffman
John William Huffman (born 1932) is a professor emeritus of organic chemistry at Clemson University who first synthesised novel cannabinoids.
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JWH-015
JWH-015 is a chemical from the naphthoylindole family that acts as a subtype-selective cannabinoid agonist.
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JWH-019
JWH-019 is an analgesic chemical from the naphthoylindole family that acts as a cannabinoid agonist at both the CB1 and CB2 receptors.
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JWH-073
JWH-073, a synthetic cannabinoid, is an analgesic chemical from the naphthoylindole family that acts as a partial agonist at both the CB1 and CB2 cannabinoid receptors.
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JWH-081
JWH-081 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors.
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JWH-122
JWH-122 is a synthetic cannabimimetic that was discovered by John W. Huffman.
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JWH-200
JWH-200 (WIN 55,225) is an analgesic chemical from the aminoalkylindole family that acts as a cannabinoid receptor agonist.
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JWH-203
JWH-203 (1-pentyl-3-(2-chlorophenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid agonist with approximately equal affinity at both the CB1 and CB2 receptors, having a Ki of 8.0nM at CB1 and 7.0nM at CB2.
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JWH-210
JWH-210 is an analgesic chemical from the naphthoylindole family, which acts as a potent cannabinoid agonist at both the CB1 and CB2 receptors, with Ki values of 0.46nM at CB1 and 0.69nM at CB2.
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JWH-250
JWH-250 or (1-pentyl-3-(2-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid agonist at both the CB1 and CB2 receptors, with a ''K''i of 11 nM at CB1 and 33 nM at CB2.
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JWH-302
JWH-302 or (1-pentyl-3-(3-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family, which acts as a cannabinoid agonist with moderate affinity at both the CB1 and CB2 receptors.
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JWH-398
JWH-398 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors.
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Khat
Khat or qat (Catha edulis, qat from القات) is a flowering plant native to the Horn of Africa and the Arabian Peninsula.
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Liquid chromatography–mass spectrometry
Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS).
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List of JWH cannabinoids
The John W. Huffman research group at Clemson University synthesized over 450 cannabinoids.
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Ministry of Health, Labour and Welfare
The is a cabinet level ministry of the Japanese government.
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Naphthoylindole
Naphthoylindoles are a class of synthetic cannabinoids.
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Partial agonist
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.
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PB-22
PB-22 (QUPIC or 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a designer drug offered by online vendors as a cannabimimetic agent, and detected being sold in synthetic cannabis products in Japan in 2013.
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QUCHIC
QUCHIC (BB-22 or 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a designer drug offered by online vendors as a cannabimimetic agent, and was first detected being sold in synthetic cannabis products in Japan in early 2013, and subsequently also in New Zealand.
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RCS-4
RCS-4, or 1-pentyl-3-(4-methoxybenzoyl)indole, is a synthetic cannabinoid drug sold under the names SR-19, BTM-4, or Eric-4 (later shortened to E-4), but originally, OBT-199.
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Salvia divinorum
Salvia divinorum (also known as sage of the diviners, ska maría pastora, seer's sage, yerba de la pastora or simply salvia) is a plant species with transient psychoactive properties when its leaves are consumed by chewing, smoking or as a tea.
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SDB-005
SDB-005 is an indazole-based synthetic cannabinoid that has been sold online as a designer drug.
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Standard for the Uniform Scheduling of Medicines and Poisons
The Standard for the Uniform Scheduling of Medicines and Poisons (SUSMP) is an Australian legislative instrument produced by the Therapeutic Goods Administration (TGA).
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Substituted phenethylamine
Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; the class is composed of all the derivative compounds of phenethylamine which can be formed by replacing, or substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents.
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Synthetic cannabinoids
Synthetic cannabinoids are a class of molecules that bind to cannabinoid receptors in the body–the same receptors that the cannabinoids in cannabis plants, such as THC and CBD–attach to.
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Tetrahydrocannabinol
Tetrahydrocannabinol (THC) is one of at least 113 cannabinoids identified in cannabis.
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THJ-018
THJ-018 is a synthetic cannabinoid that is the indazole analogue of JWH-018 and has been sold online as a designer drug.
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THJ-2201
THJ-2201 is an indazole-based synthetic cannabinoid that presumably acts as a potent agonist of the CB1 receptor and has been sold online as a designer drug.
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2C-B
2C-B or 2,5-dimethoxy-4-bromophenethylamine is a psychedelic drug of the 2C family.
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2C-P
2C-P is a relatively potent and long acting psychedelic phenethylamine and 2C compound first synthesized by Alexander Shulgin.
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Redirects here:
1-Pentyl-3-(1-Naphthoyl)Indole, AM-678, JWH-018 metabolites, NE-PIMO.
References
[1] https://en.wikipedia.org/wiki/JWH-018
