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Fibroblast growth factor receptor 3

Index Fibroblast growth factor receptor 3

Fibroblast growth factor receptor 3 is a protein that in humans is encoded by the FGFR3 gene. [1]

26 relations: Achondroplasia, Alternative splicing, Amino acid, Antibody, Basic fibroblast growth factor, Bladder cancer, Chromosome 4, Cluster of differentiation, Craniosynostosis, Exon, FGF1, FGF9, Fibroblast growth factor, Fibroblast growth factor receptor, Gene, Hydrophobe, Hypochondroplasia, Ligand (biochemistry), Osteochondrodysplasia, Protein, Protein–protein interaction, Seborrheic keratosis, Severe achondroplasia with developmental delay and acanthosis nigricans, Thanatophoric dysplasia, Transitional cell carcinoma, Tyrosine kinase.

Achondroplasia

Achondroplasia is a genetic disorder that results in dwarfism.

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Alternative splicing

Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.

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Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Basic fibroblast growth factor

FGF2, also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene.

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Bladder cancer

Bladder cancer is any of several types of cancer arising from the tissues of the urinary bladder.

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Chromosome 4

Chromosome 4 is one of the 23 pairs of chromosomes in humans.

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Cluster of differentiation

The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.

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Craniosynostosis

Craniosynostosis (from cranio, cranium; + syn, together; + ostosis relating to bone) is a condition in which one or more of the fibrous sutures in an infant (very young) skull prematurely fuses by turning into bone (ossification), thereby changing the growth pattern of the skull.

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Exon

An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.

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FGF1

FGF1, also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene.

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FGF9

Glia-activating factor is a protein that in humans is encoded by the FGF9 gene.

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Fibroblast growth factor

The fibroblast growth factors are a family of cell signalling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development.

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Fibroblast growth factor receptor

The fibroblast growth factor receptors are, as their name implies, receptors that bind to members of the fibroblast growth factor family of proteins.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Hydrophobe

In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.

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Hypochondroplasia

Hypochondroplasia (HCH) is a developmental disorder caused by an autosomal dominant genetic defect in the fibroblast growth factor receptor 3 gene (FGFR3) that results in a disproportionately short stature, micromeliaupdate 2013 and a head that appears large in comparison with the underdeveloped portions of the body.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Osteochondrodysplasia

Osteochondrodysplasia or skeletal dysplasia is a general term for a disorder of the development (dysplasia) of bone ("osteo") and cartilage ("chondro").

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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Seborrheic keratosis

A seborrheic keratosis, also known as seborrheic verruca, basal cell papilloma, or a senile wart,Freedberg, et al.

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Severe achondroplasia with developmental delay and acanthosis nigricans

Severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN), is a very rare genetic disorder.

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Thanatophoric dysplasia

Thanatophoric dysplasia (thanatophoric dwarfism) is a severe skeletal disorder characterized by a disproportionately small ribcage, extremely short limbs and folds of extra skin on the arms and legs.

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Transitional cell carcinoma

Transitional cell carcinoma, also urothelial carcinoma, is a type of cancer that typically occurs in the urinary system.

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Tyrosine kinase

A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a protein in a cell.

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Redirects here:

CD333, Cd333, Cek2, FGFR3, FGFR3 (gene), FGFR3 Inhibitor, Fibroblast growth factor receptor-3, JTK4, Jtk4.

References

[1] https://en.wikipedia.org/wiki/Fibroblast_growth_factor_receptor_3

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