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Immunoglobulin light chain

Index Immunoglobulin light chain

The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin). [1]

26 relations: Amino acid, Antibody, Antigen, B cell, B-cell lymphoma, Bence Jones protein, Camelid, Charles Janeway, Chondrichthyes, Chromosome 2, Chromosome 22, Evolution of tetrapods, IGK@, IGL@, Immunoglobulin domain, Immunoglobulin heavy chain, Immunohistochemistry, Lymphoid hyperplasia, Monoclonal antibody, Multiple myeloma, Neoplasm, Peptide, Shark, Teleost, Tetrapod, Vertebrate.

Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Antigen

In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

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B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.

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B-cell lymphoma

The B-cell lymphomas are types of lymphoma affecting B cells.

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Bence Jones protein

A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22-24 kDa.

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Camelid

Camelids are members of the biological family Camelidae, the only currently living family in the suborder Tylopoda.

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Charles Janeway

Charles Alderson Janeway, Jr. (1943–2003) was a noted immunologist.

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Chondrichthyes

Chondrichthyes (from Greek χονδρ- chondr- 'cartilage', ἰχθύς ichthys 'fish') is a class that contains the cartilaginous fishes: they are jawed vertebrates with paired fins, paired nares, scales, a heart with its chambers in series, and skeletons made of cartilage rather than bone.

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Chromosome 2

Chromosome 2 is one of the 23 pairs of chromosomes in humans.

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Chromosome 22

Chromosome 22 is one of the 23 pairs of chromosomes in human cells.

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Evolution of tetrapods

The evolution of tetrapods began about 400 million years ago in the Devonian Period with the earliest tetrapods evolved from lobe-finned fishes.

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IGK@

Immunoglobulin kappa locus, also known as IGK@, is a region on human chromosome 2 that contains genes for the kappa (κ) light chains of antibodies (or immunoglobulins).

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IGL@

Immunoglobulin lambda locus, also known as IGL@, is a region on human chromosome 22 that contains genes for the lambda light chains of antibodies (or immunoglobulins).

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Immunoglobulin domain

The immunoglobulin domain is a type of protein domain that consists of a 2-layer sandwich of 7-9 antiparallel β-strands arranged in two β-sheets with a Greek key topology, consisting of about 125 amino acids.

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Immunoglobulin heavy chain

The immunoglobulin heavy chain (IgH) is the large polypeptide subunit of an antibody (immunoglobulin).

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Immunohistochemistry

Immunohistochemistry (IHC) involves the process of selectively imaging antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues.

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Lymphoid hyperplasia

Lymphoid hyperplasia is the rapid growth proliferation of normal cells that resemble lymph tissue.

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Monoclonal antibody

Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.

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Multiple myeloma

Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Shark

Sharks are a group of elasmobranch fish characterized by a cartilaginous skeleton, five to seven gill slits on the sides of the head, and pectoral fins that are not fused to the head.

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Teleost

The teleosts or Teleostei (Greek: teleios, "complete" + osteon, "bone") are by far the largest infraclass in the class Actinopterygii, the ray-finned fishes, and make up 96% of all extant species of fish.

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Tetrapod

The superclass Tetrapoda (from Greek: τετρα- "four" and πούς "foot") contains the four-limbed vertebrates known as tetrapods; it includes living and extinct amphibians, reptiles (including dinosaurs, and its subgroup birds) and mammals (including primates, and all hominid subgroups including humans), as well as earlier extinct groups.

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Vertebrate

Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones).

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Redirects here:

Antibody light chain, Immunoglobin light chain, Immunoglobulin kappa-chains, Immunoglobulin km allotypes, Immunoglobulin lambda-chains, Immunoglobulin light chains, Immunoglobulin light-chains, Kappa and lambda light chain, Kappa-chain immunoglobulin, Kappachain immunoglobulin, Lambda light chain, Lambda light chain levels, Monoclonal light chain, Monoclonal light chains.

References

[1] https://en.wikipedia.org/wiki/Immunoglobulin_light_chain

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