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L27 domain

Index L27 domain

The L27 domain is a protein domain that is found in receptor targeting proteins Lin-2 and Lin-7 (LIN7A, LIN7B, LIN7C), as well as some protein kinases and human MPP2 protein. [1]

29 relations: Alpha helix, Antiparallel (biochemistry), Asymmetry, Biogenesis, CASK, Cell (biology), Cell division, Cell polarity, Coiled coil, Epithelium, Helix, Heteromer, Heterotetramer, Hydrophobe, Ion channel, LIN7A, LIN7B, LIN7C, MPP2, N-terminus, Protein, Protein dimer, Protein domain, Protein kinase, Protein–protein interaction, Receptor (biochemistry), Scaffold protein, Tetramer, Tight junction.

Alpha helix

The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.

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Antiparallel (biochemistry)

In biochemistry, two biopolymers are antiparallel if they run parallel to each other but with opposite alignments.

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Asymmetry

Asymmetry is the absence of, or a violation of, symmetry (the property of an object being invariant to a transformation, such as reflection).

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Biogenesis

Biogenesis is the production of new living organisms or organelles.

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CASK

Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell division

Cell division is the process by which a parent cell divides into two or more daughter cells.

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Cell polarity

Cell polarity refers to spatial differences in shape, structure, and function within a cell.

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Coiled coil

A coiled coil is a structural motif in proteins in which 2–7 alpha-helices are coiled together like the strands of a rope (dimers and trimers are the most common types).

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Helix

A helix, plural helixes or helices, is a type of smooth space curve, i.e. a curve in three-dimensional space.

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Heteromer

A heteromer is something that consists of different parts.

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Heterotetramer

A heterotetramer is protein containing four non-covalently bound subunits, wherein the subunits are not all identical.

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Hydrophobe

In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.

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Ion channel

Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore.

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LIN7A

Lin-7 homolog A is a protein that in humans is encoded by the LIN7A gene.

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LIN7B

Lin-7 homolog B is a protein that in humans is encoded by the LIN7B gene.

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LIN7C

Lin-7 homolog C is a protein that in humans is encoded by the LIN7C gene.

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MPP2

MAGUK p55 subfamily member 2 is a protein that in humans is encoded by the MPP2 gene.

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N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein dimer

In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.

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Protein domain

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.

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Protein kinase

A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation).

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Scaffold protein

In biology, scaffold proteins are crucial regulators of many key signalling pathways.

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Tetramer

A tetramer (tetra-, "four" + -mer, "parts") is an oligomer formed from four monomers or subunits.

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Tight junction

Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens) are multiprotein junctional complex whose general function is to prevent leakage of transported solutes and water and seals the paracellular pathway.

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The L27 domain.

References

[1] https://en.wikipedia.org/wiki/L27_domain

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