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STK11

Index STK11

Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a protein kinase that in humans is encoded by the STK11 gene. [1]

31 relations: Adenosine triphosphate, Allosteric regulation, AMP-activated protein kinase, CAB39, CDC37, Cutaneous condition, Dihydrotestosterone, Dominance (genetics), Estradiol, Estrogen receptor alpha, Funen, Gene, Germline, Heat shock protein 90kDa alpha (cytosolic), member A1, Homeostasis, Kinase, LYK5, Metabolism, Mutation, Neoplasm, Peutz–Jeghers syndrome, Polyp, Protein, Protein isoform, Protein–protein interaction, RNA splicing, Serine/threonine-specific protein kinase, SMARCA4, Testicle, Testosterone (medication), X-ray crystallography.

Adenosine triphosphate

Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.

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Allosteric regulation

In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than the enzyme's active site.

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AMP-activated protein kinase

5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular energy homeostasis.

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CAB39

Calcium-binding protein 39 is a protein that in humans is encoded by the CAB39 gene.

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CDC37

Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene.

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Cutaneous condition

A cutaneous condition is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, hair, nails, and related muscle and glands.

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Dihydrotestosterone

Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.

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Dominance (genetics)

Dominance in genetics is a relationship between alleles of one gene, in which the effect on phenotype of one allele masks the contribution of a second allele at the same locus.

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Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.

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Estrogen receptor alpha

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.

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Funen

Funen (Fyn), with an area of, is the third-largest island of Denmark, after Zealand and Vendsyssel-Thy.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Germline

In biology and genetics, the germline in a multicellular organism is the population of its bodily cells that are so differentiated or segregated that in the usual processes of reproduction they may pass on their genetic material to the progeny.

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Heat shock protein 90kDa alpha (cytosolic), member A1

Heat shock protein HSP 90-alpha is a protein that in humans is encoded by the HSP90AA1 gene.

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Homeostasis

Homeostasis is the tendency of organisms to auto-regulate and maintain their internal environment in a stable state.

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Kinase

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.

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LYK5

Protein kinase LYK5, also known as LYK5 or STRADα, is a human protein and also denotes the gene encoding it.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Peutz–Jeghers syndrome

Peutz–Jeghers syndrome (often abbreviated PJS) is an autosomal dominant genetic disorder characterized by the development of benign hamartomatous polyps in the gastrointestinal tract and hyperpigmented macules on the lips and oral mucosa (melanosis).

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Polyp

A polyp in zoology is one of two forms found in the phylum Cnidaria, the other being the medusa.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein isoform

A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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RNA splicing

In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).

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Serine/threonine-specific protein kinase

A serine/threonine protein kinase is a kinase enzyme that phosphorylates the OH group of serine or threonine (which have similar sidechains).

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SMARCA4

Transcription activator BRG1 also known as ATP-dependent chromatin remodeler SMARCA4 is a protein that in humans is encoded by the SMARCA4 gene.

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Testicle

The testicle or testis is the male reproductive gland in all animals, including humans.

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Testosterone (medication)

Testosterone is a medication and naturally occurring steroid hormone.

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X-ray crystallography

X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.

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Redirects here:

LKB1, Lkb1, STK11 (gene), Serine/threonine kinase 11.

References

[1] https://en.wikipedia.org/wiki/STK11

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