29 relations: Antibody, Auditory brainstem response, Blood plasma, C-Met, Citrobacter, Clinical chemistry, Dual-energy X-ray absorptiometry, Epidermal growth factor receptor, Gene, Glucose tolerance test, Hearing loss, Hematology, Hot plate test, Indirect calorimetry, International Knockout Mouse Consortium, Knockout mouse, Micronucleus test, Model organism, Mutant, Open Field (animal test), Pathogenic bacteria, Phenotypic screening, Protein, Radiography, RET proto-oncogene, Salmonella, Teratology, Transmembrane protein, Zygosity.
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shape protein produced by plasma cells that is used by the immune system to identify and neutralize pathogens such as bacteria and viruses.
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The auditory brainstem response (ABR) is an auditory evoked potential extracted from ongoing electrical activity in the brain and recorded via electrodes placed on the scalp.
Blood plasma is the pale yellow liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells.
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c-Met, also called MET and hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene (MET proto-oncogene, receptor tyrosine kinase), which earlier in the discovery process had also been called MNNG HOS transforming gene.
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Citrobacter is a genus of Gram-negative coliform bacteria in the Enterobacteriaceae family.
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Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is the area of clinical pathology that is generally concerned with analysis of bodily fluids.
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Dual-energy X-ray absorptiometry (DXA, previously DEXA) is a means of measuring bone mineral density (BMD).
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity.
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The glucose tolerance test is a medical test in which glucose is given and blood samples taken afterward to determine how quickly it is cleared from the blood.
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Hearing loss, also known as hard of hearing, anacusis, or hearing impairment, is a partial or total inability to hear.
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Hematology, also spelled haematology (from the Greek αἷμα, haima "blood" and -λoγία), is the branch of medicine concerned with the study, diagnosis, treatment, and prevention of diseases related to the blood.
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The hot plate test is a test of the pain response in animals, similar to the tail flick test.
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Indirect calorimetry calculates heat that living organisms produce by measuring either their production of carbon dioxide and nitrogen waste (frequently ammonia in aquatic organisms, or urea in terrestrial ones), or from their consumption of oxygen.
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The International Knockout Mouse Consortium (IKMC) is a scientific endeavour to produce a collection of mouse embryonic stem cell lines that together lack every gene in the genome, and then to distribute the cells to scientific researchers to create knockout mice to study.
A knockout mouse or knock-out mouse is a genetically modified mouse (Mus musculus) which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.
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A micronucleus test is a test used in toxicological screening for potential genotoxic compounds.
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A model organism is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the organism model will provide insight into the workings of other organisms.
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In biology and especially genetics, a mutant is an organism or a new genetic character arising or resulting from an instance of mutation, which is a base-pair sequence change within the DNA of a gene or chromosome of an organism.
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The Open Field Test (OFT) is an experiment used to assay general locomotor activity levels and anxiety in rodents in scientific research.
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Pathogenic bacteria are bacteria that can cause infection.
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Phenotypic screening is a type of screening used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell or an organism in a desired manner.
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Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Radiography is an imaging technique that uses electromagnetic radiation other than visible light, especially X-rays, to view the internal structure of a non-uniformly composed and opaque object (i.e. a non-transparent object of varying density and composition) such as the human body.
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The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular signalling molecules.
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Salmonella is a genus of rod-shaped (bacillus) bacteria of the Enterobacteriaceae family.
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Teratology is the study of abnormalities of physiological development.
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A transmembrane protein (TP) is a type of membrane protein spanning the entirety of the biological membrane to which it is permanently attached.
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Zygosity is the degree of similarity of the alleles for a trait in an organism.
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