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L 663536

Index L 663536

L 663536 is a leukotriene antagonist. [1]

4 relations: Antileukotriene, Arachidonate 5-lipoxygenase, Atherosclerosis, 5-lipoxygenase-activating protein.


An antileukotriene is a drug which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist (cysteinyl leukotriene receptors) and consequently opposes the function of these inflammatory mediators; leukotrienes are produced by the immune system and serve to promote bronchoconstriction, inflammation, microvascular permeability, and mucus secretion in asthma and COPD.

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Arachidonate 5-lipoxygenase

Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme (EC that in humans is encoded by the ALOX5 gene.

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Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.

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5-lipoxygenase-activating protein

Arachidonate 5-lipoxygenase-activating protein also known as 5-lipoxygenase activating protein, or FLAP, is a protein that in humans is encoded by the ALOX5AP gene.

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Redirects here:

L-663,536, MK 886, MK-886.


[1] https://en.wikipedia.org/wiki/L_663536

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