Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Free
Faster access than browser!
 

Long non-coding RNA

Index Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are defined as transcripts longer than 200 nucleotides that are not translated into protein. [1]

63 relations: Alu element, BC200 lncRNA, CDKN2BAS, CENPF, Complementary DNA, CREB-binding protein, Dihydrofolate reductase, Directionality (molecular biology), DLX2, DLX5, DLX6, DNA sequencing, Dopamine receptor D2, EP300, FANTOM, GENCODE, Genomic imprinting, GreeNC, Heat shock, HEXIM1, HEXIM2, Hox gene, Human genome, Intergenic region, KCNQ1OT1, List of long non-coding RNA databases, LncRNAdb, MALAT1, MicroRNA, Nervous tissue, Non-coding RNA, Nucleotide, Open reading frame, P-TEFb, PCGEM1, Piwi-interacting RNA, Polyadenylation, Polycomb recruitment in X chromosome inactivation, Pseudogene, Retrotransposon, RNA polymerase II, RNA polymerase III, RNA splicing, Sense (molecular biology), Sequence homology, Small interfering RNA, Small nucleolar RNA, Sonic hedgehog, Striatum, Synteny, ..., Telomere, Telomeric repeat-containing RNAs, Testicle, Tiling array, Tissue (biology), Transcription (biology), Transcription factor II B, Transcription factor II H, Translation (biology), Tsix, Ultra-conserved element, XIST, ZEB2. Expand index (13 more) »

Alu element

An Alu element is a short stretch of DNA originally characterized by the action of the Arthrobacter luteus (Alu) restriction endonuclease.

New!!: Long non-coding RNA and Alu element · See more »

BC200 lncRNA

Brain cytoplasmic 200 long-noncoding RNA (or BC200 lncRNA) is a 200 nucleotide RNA transcript found predominantly in the brain with a primary function of regulating translation by inhibiting its initiation.

New!!: Long non-coding RNA and BC200 lncRNA · See more »

CDKN2BAS

CDKN2B-AS, also known as ANRIL (antisense non-coding RNA in the INK4 locus) is a long non-coding RNA consisting of 19 exons, spanning 126.3kb in the genome, and its spliced product is a 3834bp RNA.

New!!: Long non-coding RNA and CDKN2BAS · See more »

CENPF

Centromere protein F is a protein that in humans is encoded by the CENPF gene.

New!!: Long non-coding RNA and CENPF · See more »

Complementary DNA

In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.

New!!: Long non-coding RNA and Complementary DNA · See more »

CREB-binding protein

CREB-binding protein, also known as CREBBP or CBP, is a protein that in humans is encoded by the CREBBP gene.

New!!: Long non-coding RNA and CREB-binding protein · See more »

Dihydrofolate reductase

Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.

New!!: Long non-coding RNA and Dihydrofolate reductase · See more »

Directionality (molecular biology)

Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of nucleic acid.

New!!: Long non-coding RNA and Directionality (molecular biology) · See more »

DLX2

Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene.

New!!: Long non-coding RNA and DLX2 · See more »

DLX5

Homeobox protein DLX-5 is a protein that in humans is encoded by the distal-less homeobox 5 gene, or DLX5 gene.

New!!: Long non-coding RNA and DLX5 · See more »

DLX6

Homeobox protein DLX-6 is a protein that in humans is encoded by the DLX6 gene.

New!!: Long non-coding RNA and DLX6 · See more »

DNA sequencing

DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule.

New!!: Long non-coding RNA and DNA sequencing · See more »

Dopamine receptor D2

Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.

New!!: Long non-coding RNA and Dopamine receptor D2 · See more »

EP300

Histone acetyltransferase p300 also known as p300 HAT or E1A-associated protein p300 (where E1A.

New!!: Long non-coding RNA and EP300 · See more »

FANTOM

FANTOM (Functional Annotation of the Mouse/Mammalian Genome) is an international research consortium first established in 2000 as part of the RIKEN research institute in Japan.

New!!: Long non-coding RNA and FANTOM · See more »

GENCODE

GENCODE is a scientific project in genome research and part of the ENCODE (ENCyclopedia Of DNA Elements) scale-up project.

New!!: Long non-coding RNA and GENCODE · See more »

Genomic imprinting

Genomic imprinting is an epigenetic phenomenon that causes genes to be expressed in a parent-of-origin-specific manner.

New!!: Long non-coding RNA and Genomic imprinting · See more »

GreeNC

In bioinformatics, The Green Non-Coding Database,, is a biological database that acts as an archive of plant lncRNAs and annotations.

New!!: Long non-coding RNA and GreeNC · See more »

Heat shock

In biochemistry, heat shock is the effect of subjecting a cell to a temperature that is greater than the optimal temperature range of function of the cell.

New!!: Long non-coding RNA and Heat shock · See more »

HEXIM1

Protein HEXIM1 is a protein that in humans is encoded by the HEXIM1 gene.

New!!: Long non-coding RNA and HEXIM1 · See more »

HEXIM2

Protein HEXIM2 is a protein that in humans is encoded by the HEXIM2 gene.

New!!: Long non-coding RNA and HEXIM2 · See more »

Hox gene

Hox genes, a subset of homeotic genes, are a group of related genes that control the body plan of an embryo along the head-tail axis.

New!!: Long non-coding RNA and Hox gene · See more »

Human genome

The human genome is the complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria.

New!!: Long non-coding RNA and Human genome · See more »

Intergenic region

An Intergenic region (IGR) is a stretch of DNA sequences located between genes.

New!!: Long non-coding RNA and Intergenic region · See more »

KCNQ1OT1

KCNQ1 overlapping transcript 1, also known as KCNQ1OT1, is a long non-coding RNA gene found in the KCNQ1 locus.

New!!: Long non-coding RNA and KCNQ1OT1 · See more »

List of long non-coding RNA databases

This is a list of long noncoding RNA databases, which provide information about lncRNAs.

New!!: Long non-coding RNA and List of long non-coding RNA databases · See more »

LncRNAdb

In bioinformatics, lncRNAdb is a biological database of Long non-coding RNAs The database focusses on those RNAs which have been experimentally characterised with a biological function.The database currently holds over 290 lncRNAs from around 60 species.

New!!: Long non-coding RNA and LncRNAdb · See more »

MALAT1

MALAT 1 (metastasis associated lung adenocarcinoma transcript 1) also known as NEAT2 (noncoding nuclear-enriched abundant transcript 2) is a large, infrequently spliced non-coding RNA, which is highly conserved amongst mammals and highly expressed in the nucleus.

New!!: Long non-coding RNA and MALAT1 · See more »

MicroRNA

A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.

New!!: Long non-coding RNA and MicroRNA · See more »

Nervous tissue

Nervous tissue or nerve tissue is the main tissue component of the two parts of the nervous system; the brain and spinal cord of the central nervous system (CNS), and the branching peripheral nerves of the peripheral nervous system (PNS), which regulates and controls bodily functions and activity.

New!!: Long non-coding RNA and Nervous tissue · See more »

Non-coding RNA

A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein.

New!!: Long non-coding RNA and Non-coding RNA · See more »

Nucleotide

Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.

New!!: Long non-coding RNA and Nucleotide · See more »

Open reading frame

In molecular genetics, an open reading frame (ORF) is the part of a reading frame that has the ability to be translated.

New!!: Long non-coding RNA and Open reading frame · See more »

P-TEFb

The positive transcription elongation factor, P-TEFb, plays an essential role in the regulation of transcription by RNA polymerase II (Pol II) in eukaryotes.

New!!: Long non-coding RNA and P-TEFb · See more »

PCGEM1

Prostate-specific transcript 1 (non-protein coding), also known as PCGEM1, is a long non-coding RNA gene.

New!!: Long non-coding RNA and PCGEM1 · See more »

Piwi-interacting RNA

Piwi-interacting RNA (piRNA) is the largest class of small non-coding RNA molecules expressed in animal cells.

New!!: Long non-coding RNA and Piwi-interacting RNA · See more »

Polyadenylation

Polyadenylation is the addition of a poly(A) tail to a messenger RNA.

New!!: Long non-coding RNA and Polyadenylation · See more »

Polycomb recruitment in X chromosome inactivation

Recruitment of polycomb proteins in X chromosome inactivation X chromosome inactivation (XCI) is the phenomenon that has been selected during the evolution to balance X-linked gene dosage between XX females and XY males.

New!!: Long non-coding RNA and Polycomb recruitment in X chromosome inactivation · See more »

Pseudogene

Pseudogenes are segments of DNA that are related to real genes.

New!!: Long non-coding RNA and Pseudogene · See more »

Retrotransposon

Retrotransposons (also called transposons via RNA intermediates) are genetic elements that can amplify themselves in a genome and are ubiquitous components of the DNA of many eukaryotic organisms.

New!!: Long non-coding RNA and Retrotransposon · See more »

RNA polymerase II

RNA polymerase II (RNAP II and Pol II) is a multiprotein complex.

New!!: Long non-coding RNA and RNA polymerase II · See more »

RNA polymerase III

In eukaryote cells, RNA polymerase III (also called Pol III) transcribes DNA to synthesize ribosomal 5S rRNA, tRNA and other small RNAs.

New!!: Long non-coding RNA and RNA polymerase III · See more »

RNA splicing

In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).

New!!: Long non-coding RNA and RNA splicing · See more »

Sense (molecular biology)

In molecular biology and genetics, the sense of nucleic acid molecules (often DNA or RNA) is the nature of their roles and their complementary molecules' nucleic acid units' roles in specifying amino acids.

New!!: Long non-coding RNA and Sense (molecular biology) · See more »

Sequence homology

Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life.

New!!: Long non-coding RNA and Sequence homology · See more »

Small interfering RNA

Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 base pairs in length, similar to miRNA, and operating within the RNA interference (RNAi) pathway.

New!!: Long non-coding RNA and Small interfering RNA · See more »

Small nucleolar RNA

Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs.

New!!: Long non-coding RNA and Small nucleolar RNA · See more »

Sonic hedgehog

Sonic hedgehog is a protein that in humans is encoded by the SHH ("sonic hedgehog") gene.

New!!: Long non-coding RNA and Sonic hedgehog · See more »

Striatum

The striatum, or corpus striatum (also called the neostriatum and the striate nucleus) is a nucleus (a cluster of neurons) in the subcortical basal ganglia of the forebrain.

New!!: Long non-coding RNA and Striatum · See more »

Synteny

In classical genetics, synteny describes the physical co-localization of genetic loci on the same chromosome within an individual or species.

New!!: Long non-coding RNA and Synteny · See more »

Telomere

A telomere is a region of repetitive nucleotide sequences at each end of a chromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes.

New!!: Long non-coding RNA and Telomere · See more »

Telomeric repeat-containing RNAs

Telomeric repeat-containing RNA (TERRA) is a long non-coding RNA that forms integral part of telomeric heterochromatin along with the telomeric binding proteins.

New!!: Long non-coding RNA and Telomeric repeat-containing RNAs · See more »

Testicle

The testicle or testis is the male reproductive gland in all animals, including humans.

New!!: Long non-coding RNA and Testicle · See more »

Tiling array

Tiling arrays are a subtype of microarray chips.

New!!: Long non-coding RNA and Tiling array · See more »

Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

New!!: Long non-coding RNA and Tissue (biology) · See more »

Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

New!!: Long non-coding RNA and Transcription (biology) · See more »

Transcription factor II B

Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II preinitiation complex (PIC) and aids in stimulating transcription initiation.

New!!: Long non-coding RNA and Transcription factor II B · See more »

Transcription factor II H

Transcription factor II Human (Transcription Factor II H; TFIIH) is an important protein complex, having roles in transcription of various protein-coding genes and DNA nucleotide excision repair (NER) pathways.

New!!: Long non-coding RNA and Transcription factor II H · See more »

Translation (biology)

In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus.

New!!: Long non-coding RNA and Translation (biology) · See more »

Tsix

Tsix is a non-coding RNA gene that is antisense to the Xist RNA.

New!!: Long non-coding RNA and Tsix · See more »

Ultra-conserved element

An ultra-conserved element (UCE) is a region of DNA that is identical in at least two different species.

New!!: Long non-coding RNA and Ultra-conserved element · See more »

XIST

Xist (X-inactive specific transcript) is an RNA gene on the X chromosome of the placental mammals that acts as a major effector of the X inactivation process.

New!!: Long non-coding RNA and XIST · See more »

ZEB2

Zinc finger E-box-binding homeobox 2 is a protein that in humans is encoded by the ZEB2 gene.

New!!: Long non-coding RNA and ZEB2 · See more »

Redirects here:

Large intervention non-coding RNA, Large ncRNA, Large non-coding RNA, LincRNA, LncRNA, LncRNAs, Long ncRNA, Long non coding RNA, Long noncoding RNA, Telomeric non-coding RNAs.

References

[1] https://en.wikipedia.org/wiki/Long_non-coding_RNA

OutgoingIncoming
Hey! We are on Facebook now! »