31 relations: Antidepressant, Atypical antipsychotic, Cerefolin, Colorectal cancer, Combination therapy, Cysteine, DNA, Fluorouracil, Folate, Homocysteine, International nonproprietary name, Merck Group, Metanx, Methionine, Methionine synthase, Methylation, Methylenetetrahydrofolate reductase, Orders of magnitude (mass), Pamlab, Route of administration, S-Adenosyl methionine, Salt (chemistry), Selective serotonin reuptake inhibitor, Serotonin–norepinephrine reuptake inhibitor, Switzerland, Tetrahydrofolic acid, Therapy, Thymidylate synthase, United States District Court for the Eastern District of Texas, United States International Trade Commission, 5,10-Methylenetetrahydrofolate.
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
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The atypical antipsychotics (AAP; also known as second generation antipsychotics (SGAs)) are a group of antipsychotic drugs (antipsychotic drugs in general are also known as major tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) used to treat psychiatric conditions.
Cerefolin is a prescription medication made by Pamlab that contains 5.635 mg of folate as L-methylfolate, 1 mg of vitamin B12 as methylcobalamin, 50 mg of vitamin B2 as riboflavin, and 5 mg of vitamin B6 as pyridoxine.
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Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
Combination therapy or polytherapy is therapy that uses more than one medication or modality (versus monotherapy, which is any therapy taken alone).
Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.
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Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a medication used to treat cancer.
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Folate, distinct forms of which are known as folic acid, folacin, and vitamin B9, is one of the B vitamins.
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Homocysteine is a non-proteinogenic α-amino acid.
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The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.
Merck KGaA, branded and commonly known as Merck, is a German multinational pharmaceutical, chemical and life sciences company headquartered in Darmstadt, with around 50,000 employees in around 70 countries.
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Metanx is a prescription medical food made by Pamlab that contains L-methylfolate (as Metafolin, a calcium salt of vitamin B9), methylcobalamin (vitamin B12) and pyridoxal 5'-phosphate (vitamin B6).
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Methionine (symbol Met or M) is an essential amino acid in humans.
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Methionine synthase also known as MS, MeSe, MetH is responsible for the regeneration of methionine from homocysteine.
In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.
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Methylene tetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene.
To help compare different orders of magnitude, the following lists describe various mass levels between 10−40 kg and 1053 kg.
Alfasigma USA, Inc.
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A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body.
S-Adenosyl methionineSAM-e, SAMe, SAM, S-Adenosyl-L-methionine, AdoMet, ademetionine is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation.
In chemistry, a salt is an ionic compound that can be formed by the neutralization reaction of an acid and a base.
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.
Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant drugs that treat major depressive disorder (MDD) and can also treat anxiety disorders, obsessive-compulsive disorder (OCD), attention-deficit hyperactivity disorder (ADHD), chronic neuropathic pain, fibromyalgia syndrome (FMS), and menopausal symptoms.
Switzerland, officially the Swiss Confederation, is a sovereign state in Europe.
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Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative.
Therapy (often abbreviated tx, Tx, or Tx) is the attempted remediation of a health problem, usually following a diagnosis.
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Thymidylate synthetase is an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP).
The United States District Court for the Eastern District of Texas (in case citations, E.D. Tex.) is a federal court in the Fifth Circuit (except for patent claims and claims against the U.S. government under the Tucker Act, which are appealed to the Federal Circuit).
The United States International Trade Commission (USITC, sometimes I.T.C.) is an independent, bipartisan, quasi-judicial, federal agency of the United States that provides trade expertise to both the legislative and executive branches.
5,10-Methylenetetrahydrofolate (N5,N10-Methylenetetrahydrofolate; 5,10-CH2-THF) is the substrate used by the enzyme methylenetetrahydrofolate reductase (MTHFR) to generate 5-methyltetrahydrofolate (5-MTHF, or levomefolic acid).
5-MTHF, 5-Methyltetrahydrofolate, 5-methyltetrahydrofolate, 5-methyltetrahydrofolic acid, C20H25N7O6, Depelin, Deplin, L-methylfolate, Levomefolate calcium, MTHF, Metafolin, Methyl tetrahydrofolate, Methylfolate, Methyltetrahydrofolate, Neevo, NeevoDHA, Néevo, Zervalx.