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Levomefolic acid

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Levomefolic acid (INN) (also known as 5-MTHF, L-methylfolate and 5-methyltetrahydrofolate and (6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine. [1]

25 relations: Cerefolin, Colorectal cancer, Cysteine, DNA, Fluorouracil, Folic acid, Homocysteine, International Nonproprietary Name, Merck KGaA, Metanx, Methionine, Methionine synthase, Methylation, Methylenetetrahydrofolate reductase, Orders of magnitude (mass), Pamlab, Route of administration, S-Adenosyl methionine, Salt (chemistry), Switzerland, Tetrahydrofolic acid, Thymidylate synthase, United States District Court for the Eastern District of Texas, United States International Trade Commission, 5,10-Methylenetetrahydrofolate.


Cerefolin is a prescription medication made by Pamlab that contains 5.635 mg of folate as L-methylfolate, 1 mg of vitamin B12 as methylcobalamin, 50 mg of vitamin B2 as riboflavin, and 5 mg of vitamin B6 as pyridoxine.

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Colorectal cancer

Colorectal cancer (also known as colon cancer, rectal cancer, or bowel cancer) is the development of cancer in the colon or rectum (parts of the large intestine).

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Cysteine (abbreviated as Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.

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Deoxyribonucleic acid (DNA) is a molecule that carries most of the genetic instructions used in the development, functioning and reproduction of all known living organisms and many viruses.

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Fluorouracil or 5-FU (trademarked as Adrucil (IV), Carac (topical), Efudex and Efudix (topical)) is a drug that is a pyrimidine analog which is used in the treatment of cancer.

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Folic acid

Folic acid or folate is a B vitamin.

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Homocysteine is a non-protein α-amino acid.

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International Nonproprietary Name

An International Nonproprietary Name (INN) is an official generic and nonproprietary name given to a pharmaceutical drug or active ingredient.

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Merck KGaA

Merck KGaA is a German multinational chemical, pharmaceutical and life sciences company headquartered in Darmstadt, with around 40,000 employees in around 70 countries.

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Metanx is a prescription medical food made by Pamlab that contains L-methylfolate (as Metafolin, a calcium salt of vitamin B9), methylcobalamin (vitamin B12) and pyridoxal 5'-phosphate (vitamin B6).

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Methionine (or; abbreviated as Met or M) is an α-amino acid with the chemical formula HO2CCH(NH2)CH2CH2SCH3.

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Methionine synthase

Methionine synthase also known as MS, MeSe, MetH is responsible for the regeneration of methionine from homocysteine.

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In the chemical sciences, methylation denotes the addition of a methyl group to a substrate or the substitution of an atom or group by a methyl group.

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Methylenetetrahydrofolate reductase

Methylene tetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene.

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Orders of magnitude (mass)

To help compare different orders of magnitude, the following lists describe various mass levels between 10−40 kg and 1052 kg.

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Pamlab is an American medical food company, and a division of Nestlé Health Science.

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Route of administration

A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body.

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S-Adenosyl methionine

S-Adenosyl methionineSAM-e, SAMe, SAM, S-Adenosyl-L-methionine, AdoMet, ademetionine is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation.

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Salt (chemistry)

In chemistry, a salt is an ionic compound that results from the neutralization reaction of an acid and a base.

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Switzerland (Schweiz;Swiss Standard German spelling and pronunciation. The Swiss German name is sometimes spelled as Schwyz or Schwiiz. Schwyz is also the standard German (and international) name of one of the Swiss cantons. Suisse; Svizzera; Svizra or),The latter is the common Sursilvan pronunciation.

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Tetrahydrofolic acid

Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative.

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Thymidylate synthase

Thymidylate synthetase is an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP).

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United States District Court for the Eastern District of Texas

The United States District Court for the Eastern District of Texas (in case citations, E.D. Tex.) is a federal court in the Fifth Circuit (except for patent claims and claims against the U.S. government under the Tucker Act, which are appealed to the Federal Circuit).

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United States International Trade Commission

The United States International Trade Commission (USITC sometimes I.T.C.) is an independent, bipartisan, quasi-judicial, federal agency of the United States that provides trade expertise to both the legislative and executive branches.

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5,10-Methylenetetrahydrofolate (5,10-CH2-THF) is the substrate used by the enzyme methylenetetrahydrofolate reductase (MTHFR) to generate 5-methyltetrahydrofolate (5-MTHF, or levomefolic acid).

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Redirects here:

5-MTHF, 5-Methyltetrahydrofolate, 5-methyltetrahydrofolate, 5-methyltetrahydrofolic acid, C20H25N7O6, Depelin, Deplin, L-methylfolate, Levomefolate calcium, MTHF, Metafolin, Methyl tetrahydrofolate, Methylfolate, Methyltetrahydrofolate, Neevo, NeevoDHA, Néevo, Zervalx.


[1] https://en.wikipedia.org/wiki/Levomefolic_acid

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