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Lichen planus

Index Lichen planus

Lichen planus (LP) is a disease characterized by itchy reddish-purple polygon-shaped skin lesions on the lower back, wrists, and ankles. [1]

108 relations: Acanthosis, Acitretin, Analgesic, Antigen, Apoptosis, Apremilast, Autoimmunity, Beta blocker, Betamethasone, Biopsy, Cheek, Cicatricial pemphigoid, Ciclosporin, Clinical research, Clobetasol, Conjunctiva, Corticosteroid, Cutaneous condition, Cytokine, Dermatology, Dermis, Desquamative gingivitis, Dexamethasone, Differential diagnosis, Dyspareunia, Dysphagia, Epithelium, Erythema, Esophageal stricture, Esophagitis, Esophagus, Furosemide, Gastrointestinal tract, Glans penis, Graft-versus-host disease, Grinspan's syndrome, Hepatitis B, Hepatitis C, Histology, Histopathology, HLA-DQB1, IL1A, Immunosuppressive drug, Interferon gamma, Interleukin 6, Interleukin 8, Intertriginous, Itch, Keratosis, Koebner phenomenon, ..., Lamina propria, Larynx, Lesion, Leukoplakia, Lichen, Lichen sclerosus, Lower urinary tract symptoms, Lupus erythematosus, Malaria, Metformin, Microscope, Morsicatio buccarum, Mouth ulcer, Mucous membrane, Oral candidiasis, Oral hygiene, Oral mucosa, Orthokeratosis, Papule, Parakeratosis, Pathogen, Pathognomonicity, Pemphigus vulgaris, Penicillamine, Periodic acid–Schiff stain, Peritoneum, Pimecrolimus, Prevalence, Primary biliary cholangitis, PUVA therapy, Quinine, Rete pegs, Retinoid, Scarring hair loss, Skin, Spironolactone, Stenosis, Stomatitis, Stratum basale, Stratum corneum, Stratum granulosum, Stratum spinosum, Stress (biology), Sulfasalazine, T cell, Tacrolimus, Telangiectasia, Thiazide, Topical medication, Trachonychia, Tretinoin, Triamcinolone, Tumor necrosis factor alpha, Urethra, Vagina, Vulva, Wickham striae, William James Erasmus Wilson. Expand index (58 more) »

Acanthosis

Acanthosis is diffuse epidermal hyperplasia (thickening of the skin).

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Acitretin

Acitretin (trade names Soriatane and Neotigason) is a second-generation retinoid.

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Analgesic

An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

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Antigen

In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Apremilast

Apremilast, brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis.

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Autoimmunity

Autoimmunity is the system of immune responses of an organism against its own healthy cells and tissues.

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Beta blocker

Beta blockers, also written β-blockers, are a class of medications that are particularly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack (myocardial infarction) after a first heart attack (secondary prevention).

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Betamethasone

Betamethasone is a steroid medication.

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Biopsy

A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist involving extraction of sample cells or tissues for examination to determine the presence or extent of a disease.

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Cheek

Cheeks (buccae) constitute the area of the face below the eyes and between the nose and the left or right ear.

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Cicatricial pemphigoid

Cicatricial pemphigoid (also known as "Mucous Membrane Pemphigoid", "MMP", "Benign mucosal pemphigoid," "Benign mucous membrane pemphigoid," "Ocular pemphigus," and "Scarring pemphigoid") is a rare chronic autoimmune subepithelial blistering disease characterized by erosive skin lesions of the mucous membranes and skin that results in scarring of at least some sites of involvement.

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Ciclosporin

Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product.

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Clinical research

Clinical research is a branch of healthcare science that determines the safety and effectiveness (efficacy) of medications, devices, diagnostic products and treatment regimens intended for human use.

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Clobetasol

Clobetasol (brand name Dermovat) is a synthetic glucocorticoid corticosteroid which is marketed in Denmark.

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Conjunctiva

The conjunctiva lines the inside of the eyelids and covers the sclera (the white of the eye).

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Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.

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Cutaneous condition

A cutaneous condition is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, hair, nails, and related muscle and glands.

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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Dermatology

Dermatology (from ancient Greek δέρμα, derma which means skin and λογία, logia) is the branch of medicine dealing with the skin, nails, hair and its diseases.

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Dermis

The dermis or corium is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from stress and strain.

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Desquamative gingivitis

Desquamative gingivitis (DG) is an erythematous (red), desquamatous (shedding) and ulcerated appearance of the gums.

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Dexamethasone

Dexamethasone is a type of corticosteroid medication.

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Differential diagnosis

In medicine, a differential diagnosis is the distinguishing of a particular disease or condition from others that present similar clinical features.

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Dyspareunia

Dyspareunia is painful sexual intercourse due to medical or psychological causes.

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Dysphagia

Dysphagia is the medical term for the symptom of difficulty in swallowing.

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Erythema

Erythema (from the Greek erythros, meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries.

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Esophageal stricture

A benign esophageal stricture, or peptic stricture, is a narrowing or tightening of the esophagus that causes swallowing difficulties.

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Esophagitis

Esophagitis (or oesophagitis) is an inflammation of the esophagus.

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Esophagus

The esophagus (American English) or oesophagus (British English), commonly known as the food pipe or gullet (gut), is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach.

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Furosemide

Furosemide, sold under the brand name Lasix among others, is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.

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Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

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Glans penis

The glans penis is the sensitive bulbous structure at the distal end of the human penis.

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Graft-versus-host disease

Graft-versus-host disease (GvHD) is a medical complication following the receipt of transplanted tissue from a genetically different person.

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Grinspan's syndrome

Grinspan syndrome is a syndrome characterized by presence of the triad: essential hypertension, diabetes mellitus, and oral lichen planus.

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Hepatitis B

Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver.

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Hepatitis C

Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver.

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Histology

Histology, also microanatomy, is the study of the anatomy of cells and tissues of plants and animals using microscopy.

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Histopathology

Histopathology (compound of three Greek words: ἱστός histos "tissue", πάθος pathos "suffering", and -λογία -logia "study of") refers to the microscopic examination of tissue in order to study the manifestations of disease.

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HLA-DQB1

Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene and also denotes the genetic locus that contains this gene.

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IL1A

Interleukin 1 alpha (IL-1α) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene.

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Immunosuppressive drug

Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system.

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Interferon gamma

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.

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Interleukin 6

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.

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Interleukin 8

Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.

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Intertriginous

In medicine, an intertriginous area is where two skin areas may touch or rub together.

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Itch

Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.

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Keratosis

Keratosis (from kerat- + -osis) is a growth of keratin on the skin or on mucous membranes stemming from keratinocytes, the prominent cell type in the epidermis.

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Koebner phenomenon

The Koebner phenomenon or Köbner phenomenon, also called the Koebner response or the isomorphic response, attributed to Heinrich Köbner, is the appearance of skin lesions on lines of trauma.

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Lamina propria

The lamina propria is a thin layer of connective tissue that forms part of the moist linings known as mucous membranes or mucosa, which line various tubes in the body, such as the respiratory tract, the gastrointestinal tract, and the urogenital tract.

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Larynx

The larynx, commonly called the voice box, is an organ in the top of the neck of tetrapods involved in breathing, producing sound, and protecting the trachea against food aspiration.

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Lesion

A lesion is any abnormal damage or change in the tissue of an organism, usually caused by disease or trauma.

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Leukoplakia

Leukoplakia generally refers to a firmly attached white patch on a mucous membrane which is associated with an increased risk of cancer.

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Lichen

A lichen is a composite organism that arises from algae or cyanobacteria living among filaments of multiple fungi in a symbiotic relationship.

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Lichen sclerosus

Lichen sclerosus (LS) is a skin disease of unknown cause, commonly appearing as whitish patches on the genitals, which can affect any body part of any person but has a strong preference for the genitals (penis, vulva) and is also known as balanitis xerotica obliterans (BXO) when it affects the penis.

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Lower urinary tract symptoms

Lower urinary tract symptoms (LUTS) refer to a group of clinical symptoms involving the bladder, urinary sphincter, urethra, and, in men, the prostate.

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Lupus erythematosus

Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues.

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Malaria

Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.

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Metformin

Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight.

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Microscope

A microscope (from the μικρός, mikrós, "small" and σκοπεῖν, skopeîn, "to look" or "see") is an instrument used to see objects that are too small to be seen by the naked eye.

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Morsicatio buccarum

Morsicatio buccarum (also termed chronic cheek biting and chronic cheek chewing) is a condition characterized by chronic irritation or injury to the buccal mucosa (the lining of the inside of the cheek within the mouth), caused by repetitive chewing, biting or nibbling.

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Mouth ulcer

A mouth ulcer is an ulcer that occurs on the mucous membrane of the oral cavity.

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Mucous membrane

A mucous membrane or mucosa is a membrane that lines various cavities in the body and covers the surface of internal organs.

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Oral candidiasis

Oral candidiasis, also known as oral thrush among other names, is candidiasis that occurs in the mouth.

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Oral hygiene

Oral hygiene is the practice of keeping one's mouth clean and free of disease and other problems (e.g. bad breath) by regular brushing and cleaning between the teeth.

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Oral mucosa

The oral mucosa is the mucous membrane lining the inside of the mouth and consists of stratified squamous epithelium termed oral epithelium and an underlying connective tissue termed lamina propria.

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Orthokeratosis

Orthokeratosis is Hyperkeratosis without parakeratosis.

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Papule

A papule is a circumscribed, solid elevation of skin with no visible fluid, varying in area from a pinhead to 1 cm.

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Parakeratosis

Parakeratosis is a mode of keratinization characterized by the retention of nuclei in the stratum corneum.

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Pathogen

In biology, a pathogen (πάθος pathos "suffering, passion" and -γενής -genēs "producer of") or a '''germ''' in the oldest and broadest sense is anything that can produce disease; the term came into use in the 1880s.

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Pathognomonicity

Pathognomonic (rarely spelled pathognomic and sometimes misspelled as pathomnemonic) is a term, often used in medicine, that means characteristic for a particular disease.

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Pemphigus vulgaris

Pemphigus vulgaris is a rare chronic blistering skin disease and the most common form of pemphigus.

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Penicillamine

Penicillamine, sold under the trade names of Cuprimine among others, is a medication primarily used for the treatment of Wilson's disease.

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Periodic acid–Schiff stain

Periodic acid–Schiff (PAS) is a staining method used to detect polysaccharides such as glycogen, and mucosubstances such as glycoproteins, glycolipids and mucins in tissues.

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Peritoneum

The peritoneum is the serous membrane that forms the lining of the abdominal cavity or coelom in amniotes and some invertebrates, such as annelids.

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Pimecrolimus

Pimecrolimus is an immunomodulating agent of the calcineurin inhibitor class used in the treatment of atopic dermatitis (eczema).

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Prevalence

Prevalence in epidemiology is the proportion of a particular population found to be affected by a medical condition (typically a disease or a risk factor such as smoking or seat-belt use).

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Primary biliary cholangitis

Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver.

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PUVA therapy

PUVA (psoralen and ultraviolet A) is an ultraviolet light therapy treatment for eczema, psoriasis, graft-versus-host disease, vitiligo, mycosis fungoides, large-plaque parapsoriasis and cutaneous T-cell lymphoma using the sensitizing effects of the drug psoralen.

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Quinine

Quinine is a medication used to treat malaria and babesiosis.

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Rete pegs

Rete pegs (also known as rete processes or rete ridges) are the epithelial extensions that project into the underlying connective tissue in both skin and mucous membranes.

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Retinoid

The retinoids are a class of chemical compounds that are vitamers of vitamin A or are chemically related to it.

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Scarring hair loss

Scarring hair loss, also known as cicatricial alopecia, is the loss of hair which is accompanied with scarring.

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Skin

Skin is the soft outer tissue covering vertebrates.

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Spironolactone

Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.

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Stenosis

A stenosis is an abnormal narrowing in a blood vessel or other tubular organ or structure.

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Stomatitis

Stomatitis is inflammation of the mouth and lips.

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Stratum basale

The stratum basale (basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five layers of the epidermis, the outer covering of skin in mammals.

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Stratum corneum

The stratum corneum (Latin for 'horny layer') is the outermost layer of the epidermis, consisting of dead cells (corneocytes).

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Stratum granulosum

The stratum granulosum (or granular layer) is a thin layer of cells in the epidermis.

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Stratum spinosum

The stratum spinosum (or spinous layer/prickle cell layer) is a layer of the epidermis found between the stratum granulosum and stratum basale.

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Stress (biology)

Physiological or biological stress is an organism's response to a stressor such as an environmental condition.

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Sulfasalazine

Sulfasalazine (SSZ), sold under the trade name Azulfidine among others, is a medication used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease.

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T cell

A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.

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Tacrolimus

No description.

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Telangiectasia

Telangiectasias, also known as spider veins, are small dilated blood vessels near the surface of the skin or mucous membranes, measuring between 0.5 and 1 millimeter in diameter.

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Thiazide

Thiazide is a type of molecule and a class of diuretics often used to treat hypertension (high blood pressure) and edema (such as that caused by heart failure, liver failure, or kidney failure).

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Topical medication

A topical medication is a medication that is applied to a particular place on or in the body.

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Trachonychia

Trachyonychia, sometimes called sandpapered nails,Fawcett, Ronald S.; Hart, Thomas M.; Linford, Sean;Stulberg, Daniel L. (2004).

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Tretinoin

Tretinoin, also known as all-trans retinoic acid (ATRA), is medication used for the treatment of acne and acute promyelocytic leukemia.

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Triamcinolone

Triamcinolone is an intermediate-acting synthetic glucocorticoid given orally, by injection, by inhalation, or as a topical ointment or cream.

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Tumor necrosis factor alpha

Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

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Urethra

In anatomy, the urethra (from Greek οὐρήθρα – ourḗthrā) is a tube that connects the urinary bladder to the urinary meatus for the removal of urine from the body.

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Vagina

In mammals, the vagina is the elastic, muscular part of the female genital tract.

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Vulva

The vulva (wrapper, covering, plural vulvae or vulvas) consists of the external female sex organs.

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Wickham striae

Wickham striae are whitish lines visible in the papules of lichen planus and other dermatoses, typically in the oral mucosa.

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William James Erasmus Wilson

Sir William James Erasmus Wilson FRCS FRS (25 November 1809 – 7 August 1884), generally known as Sir Erasmus Wilson, was an English surgeon and dermatologist.

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References

[1] https://en.wikipedia.org/wiki/Lichen_planus

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