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Index Lipophilicity

Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene. [1]

33 relations: Amphiphile, Chemical compound, Detergent, Emulsion, Fat, Fluorocarbon, Fluorosurfactant, Greek language, Hexane, Hydrocarbon, Hydrogen bond, Hydrophile, Hydrophobe, Ionic partition diagram, ITIES, IUPAC books, Lipid, Lipophilic bacteria, Lipophobicity, London dispersion force, Micelle, Microemulsion, Oil, Oxybenzone, Partition coefficient, Phosphate, Phospholipid, Silicone, Solvent, Surface tension, Surfactant, Thermodynamics, Toluene.


An amphiphile (from the Greek αμφις, amphis: both and φιλíα, philia: love, friendship) is a chemical compound possessing both hydrophilic (water-loving, polar) and lipophilic (fat-loving) properties.

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Chemical compound

A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) composed of atoms from more than one element held together by chemical bonds.

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A detergent is a surfactant or a mixture of surfactants with cleaning properties in dilute solutions.

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An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or unblendable).

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Fat is one of the three main macronutrients, along with carbohydrate and protein.

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Fluorocarbons, sometimes referred to as perfluorocarbons or PFCs, are, strictly speaking, organofluorine compounds with the formula CxFy, i.e. they contain only carbon and fluorine, though the terminology is not strictly followed.

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Fluorosurfactants (also fluorinated surfactants, perfluorinated alkylated substances or PFASs) are synthetic organofluorine chemical compounds that have multiple fluorine atoms.

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Greek language

Greek (Modern Greek: ελληνικά, elliniká, "Greek", ελληνική γλώσσα, ellinikí glóssa, "Greek language") is an independent branch of the Indo-European family of languages, native to Greece and other parts of the Eastern Mediterranean and the Black Sea.

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Hexane is an alkane of six carbon atoms, with the chemical formula C6H14.

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In organic chemistry, a hydrocarbon is an organic compound consisting entirely of hydrogen and carbon.

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Hydrogen bond

A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.

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A hydrophile is a molecule or other molecular entity that is attracted to water molecules and tends to be dissolved by water.

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In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.

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Ionic partition diagram

Similar to Pourbaix's diagram for the speciation of redox species as a function of the redox potential and the pH, ionic partition diagrams indicate in which an acid or a base are predominantly present in a biphasic system as a function of the Galvani potential difference between the two phases and the pH of the aqueous solution Ionic partition diagram of an hydrophilic acid AH in a biphasic water/organic solvent system.

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In electrochemistry, ITIES is an acronym for the "''i''nterface between two immiscible ''e''lectrolyte solutions".

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IUPAC books

The International Union of Pure and Applied Chemistry publishes many books, which contain its complete list of definitions.

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In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.

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Lipophilic bacteria

Lipophilic bacteria (fat-loving bacteria) are bacteria that may proliferate in lipids.

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Lipophobicity, also sometimes called lipophobia (from the Greek λιποφοβία from λίπος lipos "fat" and φόβος phobos "fear"), is a chemical property of chemical compounds which means "fat rejection", literally "fear of fat".

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London dispersion force

London dispersion forces (LDF, also known as dispersion forces, London forces, instantaneous dipole–induced dipole forces, or loosely van der Waals forces) are a type of force acting between atoms and molecules.

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A micelle or micella (plural micelles or micellae, respectively) is an aggregate (or supramolecular assembly) of surfactant molecules dispersed in a liquid colloid.

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Microemulsions are clear, thermodynamically stable, isotropic liquid mixtures of oil, water and surfactant, frequently in combination with a cosurfactant.

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An oil is any nonpolar chemical substance that is a viscous liquid at ambient temperatures and is both hydrophobic (does not mix with water, literally "water fearing") and lipophilic (mixes with other oils, literally "fat loving").

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Oxybenzone or benzophenone-3 (trade names Milestab 9, Eusolex 4360, Escalol 567, KAHSCREEN BZ-3) is an organic compound.

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Partition coefficient

In the physical sciences, a partition-coefficient (P) or distribution-coefficient (D) is the ratio of concentrations of a compound in a mixture of two immiscible phases at equilibrium.

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A phosphate is chemical derivative of phosphoric acid.

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Phospholipids are a class of lipids that are a major component of all cell membranes.

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Silicones, also known as polysiloxanes, are polymers that include any inert, synthetic compound made up of repeating units of siloxane, which is a chain of alternating silicon atoms and oxygen atoms, combined with carbon, hydrogen, and sometimes other elements.

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A solvent (from the Latin solvō, "loosen, untie, solve") is a substance that dissolves a solute (a chemically distinct liquid, solid or gas), resulting in a solution.

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Surface tension

Surface tension is the elastic tendency of a fluid surface which makes it acquire the least surface area possible.

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Surfactants are compounds that lower the surface tension (or interfacial tension) between two liquids, between a gas and a liquid, or between a liquid and a solid.

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Thermodynamics is the branch of physics concerned with heat and temperature and their relation to energy and work.

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Toluene, also known as toluol, is an aromatic hydrocarbon.

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Fat soluble, Fat-soluble, Lipid solubility, Lipid soluble, Lipid-soluble, Lipophile, Lipophilia, Lipophilic, Lipophillic, Liposolubility, Liposoluble, Lypophilic.


[1] https://en.wikipedia.org/wiki/Lipophilicity

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