118 relations: Abbott Laboratories, Agomelatine, Alcon, Amgen, Amitriptyline, Astellas Pharma, AstraZeneca, Beclometasone dipropionate, Bepridil, Betamethasone, Bortezomib, Bristol-Myers Squibb, Brompheniramine, Candicidin, Cefpodoxime, Cefuroxime, Conivaptan, Desogestrel, Desonide, Diatrizoate, Diazepam, Eflornithine, Eli Lilly and Company, Enalapril, Endo International plc, Epinephrine (medication), Estradiol (medication), Ethinamate, Etoposide, Genentech, GlaxoSmithKline, Hetacillin, Hoffmann-La Roche, Iloprost, Influenza vaccine, International nonproprietary name, Iron sucrose, Isoprenaline, Isoxsuprine, Laboratoires Servier, Mebendazole, MediGene, Methoxamine, Minocycline, Novartis, Novo Nordisk, Octatropine methylbromide, Oxamniquine, Panitumumab, Paracetamol, ..., Phenoxymethylpenicillin, Piperazine, Pipobroman, Povidone-iodine, Rimexolone, Salbutamol, Sanofi, Schering-Plough, Solifenacin, Sulfafurazole, Sulfanilamide, Technetium (99mTc) nofetumomab merpentan, Tioconazole, Tretinoin, Triflupromazine, United States Adopted Name, Urea-containing cream, Vabicaserin, Vadimezan, Valaciclovir, Valdecoxib, Valganciclovir, Valine, Valnemulin, Valnoctamide, Valofane, Valperinol, Valproate, Valproate pivoxil, Valpromide, Valrubicin, Valsartan, Valspodar, Vancomycin, Vandetanib, Vaniprevir, Vanoxerine, Vapaliximab, Vapreotide, Vardenafil, Varenicline, Varespladib, Varicella vaccine, Vasopressin, Vatalanib, Vatelizumab, Vecuronium bromide, Vedaclidine, Vedaprofen, Vedolizumab, Velaglucerase alfa, Veliparib, Velneperit, Veltuzumab, Velusetrag, Vemurafenib, Venlafaxine, Vepalimomab, Veralipride, Verapamil, Vernakalant, Versed, Verteporfin, Verucerfont, Vesencumab, Vesnarinone, Vinblastine, Zafirlukast. Expand index (68 more) » « Shrink index
Abbott Laboratories is an American health care company with headquarters in Lake Bluff, Illinois, United States.
Agomelatine (brand names Valdoxan, Melitor, Thymanax) is an atypical antidepressant developed by the pharmaceutical company Servier.
Alcon is an American global medical company specializing in eye care products and headquartered in Hünenberg, Switzerland.
Amgen Inc. (formerly Applied Molecular Genetics Inc.) is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California.
Amitriptyline, sold under the brand name Elavil among others, is a medicine primarily used to treat a number of mental illnesses.
is a Japanese pharmaceutical company, formed on 1 April 2005 from the merger of and.
AstraZeneca plc is an Anglo–Swedish multinational pharmaceutical and biopharmaceutical company.
Beclometasone dipropionate, also spelled beclomethasone dipropionate and sold under the brand name Qvar among others, is a steroid medication.
Bepridil (trade name Vascor) is an amine calcium channel blocker once used to treat angina.
Betamethasone is a steroid medication.
Bortezomib (BAN, INN and USAN; marketed as Velcade by Takeda Oncology; Chemobort by Cytogen and Bortecad by Cadila Healthcare) is an anti-cancer drug and the first therapeutic proteasome inhibitor to be used in humans.
Bristol-Myers Squibb (BMS) is an American pharmaceutical company, headquartered in New York City.
Brompheniramine (Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane), commonly marketed as its salt brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class.
Candicidin is an antifungal compound obtained from Streptomyces griseus.
Cefpodoxime is an oral, third-generation cephalosporin antibiotic.
Cefuroxime is an enteral second-generation cephalosporin antibiotic.
Conivaptan (YM 087, brand name Vaprisol) is a non-peptide inhibitor of arginine vasopressin (AVP)receptor.
Desogestrel, sold under the brand names Cerazette and Mircette among many others, is a progestin medication which is used in birth control pills for women.
Desonide (INN) is a low-potency topical corticosteroid anti-inflammatory that has been available since the 1970s.
Diatrizoate, also known as amidotrizoate, is a contrast agent used during X-rays.
Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that typically produces a calming effect.
Eflornithine, sold under the brand name Vaniqa among others, is a medication used to treat African trypanosomiasis (sleeping sickness) and excessive hair growth on the face in women.
Eli Lilly and Company is a global pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries.
Enalapril, sold under the brand name Vasotec among others, is a medication used to treat high blood pressure, diabetic kidney disease, and heart failure.
Endo International plc is a generics and specialty branded pharmaceutical company.
Epinephrine, also known as adrenalin or adrenaline, is a medication and hormone.
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
Ethinamate (Valamin, Valmid) is a short-acting carbamate-derivative sedative-hypnotic medication used to treat insomnia.
Etoposide, sold under the brand name Etopophos among others, is a chemotherapy medication used for the treatments of a number of types of cancer.
Genentech, Inc., is a biotechnology corporation which became a subsidiary of Roche in 2009.
GlaxoSmithKline plc (GSK) is a British pharmaceutical company headquartered in Brentford, London.
Hetacillin is a beta-lactam antibiotic that is part of the aminopenicillin family.
Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood can't flow to the tissues.
Influenza vaccines, also known as flu shots or flu jabs, are vaccines that protect against infection by Influenza viruses.
The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.
Iron sucrose (brand name Venofer) is an intravenously administered iron product indicated in the treatment of iron deficiency anemia.
Isoprenaline, or isoproterenol, is a medication used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma.
Isoxsuprine (used as isoxsuprine hydrochloride) is a drug used as a vasodilator in humans (under the trade name Duvadilan) and equines.
Servier Laboratories (French: Laboratoires Servier, often abbreviated to Servier) is a privately owned French pharmaceutical company that specialises in medication for cardiological and rheumatological conditions, as well as for diabetes and clinical depression.
Mebendazole (MBZ) is a medication used to treat a number of parasitic worm infestations.
Medigene AG is a publicly listed (Frankfurt: MDG1, prime standard) biotechnology company headquartered in Martinsried near Munich, Germany.
Methoxamine is an α1-adrenergic receptor agonist, somewhat similar in structure to butaxamine and 2,5-DMA.
Minocycline is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group.
Novartis International AG is a Swiss multinational pharmaceutical company based in Basel, Switzerland.
Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsværd, Denmark, with production facilities in eight countries, and affiliates or offices in 75 countries.
Octatropine methylbromide (INN) or anisotropine methylbromide (USAN), trade names Valpin, Endovalpin, Lytispasm and others, Retrieved on August 31, 2008 through Google Book Search.
Oxamniquine, sold under the brand name Vansil among others, is a medication used to treat schistosomiasis due to Schistosoma mansoni.
Panitumumab (INN), formerly ABX-EGF, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans).
--> Acetanilide was the first aniline derivative serendipitously found to possess analgesic as well as antipyretic properties, and was quickly introduced into medical practice under the name of Antifebrin by A. Cahn and P. Hepp in 1886. But its unacceptable toxic effects, the most alarming being cyanosis due to methemoglobinemia, prompted the search for less toxic aniline derivatives. Harmon Northrop Morse had already synthesised paracetamol at Johns Hopkins University via the reduction of ''p''-nitrophenol with tin in glacial acetic acid in 1877, but it was not until 1887 that clinical pharmacologist Joseph von Mering tried paracetamol on humans. In 1893, von Mering published a paper reporting on the clinical results of paracetamol with phenacetin, another aniline derivative. Von Mering claimed that, unlike phenacetin, paracetamol had a slight tendency to produce methemoglobinemia. Paracetamol was then quickly discarded in favor of phenacetin. The sales of phenacetin established Bayer as a leading pharmaceutical company. Overshadowed in part by aspirin, introduced into medicine by Heinrich Dreser in 1899, phenacetin was popular for many decades, particularly in widely advertised over-the-counter "headache mixtures", usually containing phenacetin, an aminopyrine derivative of aspirin, caffeine, and sometimes a barbiturate. Paracetamol is the active metabolite of phenacetin and acetanilide, both once popular as analgesics and antipyretics in their own right. However, unlike phenacetin, acetanilide and their combinations, paracetamol is not considered carcinogenic at therapeutic doses. Von Mering's claims remained essentially unchallenged for half a century, until two teams of researchers from the United States analyzed the metabolism of acetanilide and paracetamol. In 1947 David Lester and Leon Greenberg found strong evidence that paracetamol was a major metabolite of acetanilide in human blood, and in a subsequent study they reported that large doses of paracetamol given to albino rats did not cause methemoglobinemia. In three papers published in the September 1948 issue of the Journal of Pharmacology and Experimental Therapeutics, Bernard Brodie, Julius Axelrod and Frederick Flinn confirmed using more specific methods that paracetamol was the major metabolite of acetanilide in human blood, and established that it was just as efficacious an analgesic as its precursor. They also suggested that methemoglobinemia is produced in humans mainly by another metabolite, phenylhydroxylamine. A follow-up paper by Brodie and Axelrod in 1949 established that phenacetin was also metabolised to paracetamol. This led to a "rediscovery" of paracetamol. It has been suggested that contamination of paracetamol with 4-aminophenol, the substance von Mering synthesised it from, may be the cause for his spurious findings. Paracetamol was first marketed in the United States in 1950 under the name Triagesic, a combination of paracetamol, aspirin, and caffeine. Reports in 1951 of three users stricken with the blood disease agranulocytosis led to its removal from the marketplace, and it took several years until it became clear that the disease was unconnected. Paracetamol was marketed in 1953 by Sterling-Winthrop Co. as Panadol, available only by prescription, and promoted as preferable to aspirin since it was safe for children and people with ulcers. In 1955, paracetamol was marketed as Children's Tylenol Elixir by McNeil Laboratories. In 1956, 500 mg tablets of paracetamol went on sale in the United Kingdom under the trade name Panadol, produced by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc. In 1963, paracetamol was added to the British Pharmacopoeia, and has gained popularity since then as an analgesic agent with few side-effects and little interaction with other pharmaceutical agents. Concerns about paracetamol's safety delayed its widespread acceptance until the 1970s, but in the 1980s paracetamol sales exceeded those of aspirin in many countries, including the United Kingdom. This was accompanied by the commercial demise of phenacetin, blamed as the cause of analgesic nephropathy and hematological toxicity. In 1988 Sterling Winthrop was acquired by Eastman Kodak which sold the over the counter drug rights to SmithKline Beecham in 1994. Available without a prescription since 1959, it has since become a common household drug. Patents on paracetamol have long expired, and generic versions of the drug are widely available.
Phenoxymethylpenicillin, also known as penicillin V and penicillin VK, is an antibiotic useful for the treatment of a number of bacterial infections.
Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring.
Pipobroman (trade names Vercite, Vercyte) is an anti-cancer drug that probably acts as an alkylating agent.
Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery.
Rimexolone is a glucocorticoid steroid used to treat inflammation in the eye.
Salbutamol, also known as albuterol and marketed as Ventolin among other names, is a medication that opens up the medium and large airways in the lungs.
Sanofi S.A. is a French multinational pharmaceutical company headquartered in Gentilly, France, as of 2013 the world's fifth-largest by prescription sales.
Schering-Plough Corporation was a United States-based pharmaceutical company.
Solifenacin (INN, trade name Vesicare) is a medicine of the antimuscarinic class and was developed for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence.
Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an oxazole substituent.
Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial.
Technetium (99mTc) nofetumomab merpentan (trade name Verluma) is a mouse monoclonal antibody derivative used in the diagnosis of lung cancer, gastrointestinal, breast, ovary, pancreas, kidney, cervix, and bladder carcinoma.
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast.
Tretinoin, also known as all-trans retinoic acid (ATRA), is medication used for the treatment of acne and acute promyelocytic leukemia.
Triflupromazine (Vesprin) is an antipsychotic medication of the phenothiazine class.
United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States.
Urea, also known as carbamide-containing cream, is used as a medication and applied to the skin to treat dryness and itching such as may occur in psoriasis, dermatitis, or ichthyosis.
Vabicaserin (codenamed SCA-136) was a novel antipsychotic and anorectic under development by Wyeth.
Vadimezan (also known as or ASA404 and DMXAA) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.
Valaciclovir, also spelled valacyclovir, is an antiviral drug used in the management of herpes simplex, herpes zoster (shingles), and herpes B. It is a prodrug, being converted in vivo to aciclovir.
Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms.
Valganciclovir, sold under the brandname Valcyte among others, is an antiviral medication used to treat cytomegalovirus (CMV) infection in those with HIV/AIDS or following organ transplant.
Valine (symbol Val or V) is an α-amino acid that is used in the biosynthesis of proteins.
Valnemulin (trade name Econor) is a pleuromutilin antibiotic used to treat swine dysentery, ileitis, colitis and pneumonia.
Valnoctamide (INN, USAN) has been used in France as a sedative-hypnotic since 1964.
Valofane is a sedative drug structurally related to the barbiturates and similar drugs such as primidone.
Valperinol (INN; GA 30-905) is a drug which acts as a calcium channel blocker.
Valproate (VPA), and its valproic acid, sodium valproate, and valproate semisodium forms, are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches.
Valproate pivoxil (Pivadin, Valproxen) is an anticonvulsant used in the treatment of epilepsy.
Valpromide (marketed as Depamide by Sanofi-Aventis) is a carboxamide derivative of valproic acid used in the treatment of epilepsy and some affective disorders.
Valrubicin (N-trifluoroacetyladriamycin-14-valerate, trade name Valstar) is a chemotherapy drug used to treat bladder cancer.
Valsartan (trade name Diovan) is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack.
Valspodar (PSC833) is an experimental cancer treatment and chemosensitizer.
Vancomycin is an antibiotic used to treat a number of bacterial infections.
Vandetanib (INN, trade name Caprelsa) is an anti-cancer drug that is used for the treatment of certain tumours of the thyroid gland.
Vaniprevir (MK-7009) is a macrocyclic hepatitis C virus (HCV) NS3/4A protease inhibitor, developed by Merck & Co., which is currently in clinical testing.
Vanoxerine (GBR-12909) is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor (DRI).
Vapaliximab is a chimeric monoclonal antibody and an immunosuppressive drug.
Vapreotide (Sanvar) is a synthetic somatostatin analog.
Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction that is sold under the trade names Levitra (Bayer AG, GSK, and SP), Staxyn in India, and Vivanza in Italy.
Varenicline (trade name Chantix and Champix), is a prescription medication used to treat nicotine addiction.
Varespladib is an inhibitor of the IIa, V, and X isoforms of secretory phospholipase A2 (sPLA2).
Varicella vaccine, also known as chickenpox vaccine, is a vaccine that protects against chickenpox.
Vasopressin, also named antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized as a peptide prohormone in neurons in the hypothalamus, and is converted to AVP.
Vatalanib (INN, codenamed PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis.
Vatelizumab is an immunomodulator.
Vecuronium bromide, sold under the brand name Norcuron among others, is a medication used as part of general anesthesia to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Vedaclidine (INN, codenamed LY-297,802, NNC 11-1053) is a novel analgesic drug which acts as a mixed agonist–antagonist at muscarinic acetylcholine receptors, being a potent and selective agonist for the M1 and M4 subtypes, yet an antagonist at the M2, M3 and M5 subtypes.
Vedaprofen is a nonsteroidal anti-inflammatory drug (NSAID) used in veterinary medicine for the treatment of pain and inflammation due to musculoskeletal disorders in dogs and horses and for the treatment of pain due to horse colic.
Vedolizumab (trade name Entyvio) is a monoclonal antibody developed by Millennium Pharmaceuticals, Inc (a subsidiary of Takeda Pharmaceuticals) for the treatment of ulcerative colitis and Crohn's disease.
Velaglucerase alfa (trade name VPRIV), manufactured by Shire plc is a hydrolytic lysosomal glucocerebroside-specific enzyme, which is a recombinant form of glucocerebrosidase indicated as a long-term enzyme replacement therapy for those suffering of Gaucher disease Type 1.
Veliparib (ABT-888) is a potential anti-cancer drug acting as a PARP inhibitor.
Velneperit (S-2367) is a drug developed by Shionogi, which acts as a potent and selective antagonist for the Neuropeptide Y receptor Y5.
Veltuzumab is a monoclonal antibody (targeted at CD20) which is being investigated for the treatment of non-Hodgkin's lymphoma.
Velusetrag (INN, USAN; previously known as TD-5108) is an experimental drug candidate for the treatment of gastric neuromuscular disorders including gastroparesis, and lower gastrointestinal motility disorders including chronic idiopathic constipation and irritable bowel syndrome.
Vemurafenib (INN, marketed as Zelboraf) is a B-Raf enzyme inhibitor developed by Plexxikon (now part of Daiichi-Sankyo) and Genentech for the treatment of late-stage melanoma.
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant of the selective serotonin-norepinephrine reuptake inhibitor (SNRI) class.
Vepalimomab is a mouse monoclonal antibody developed for the treatment of inflammations.
Veralipride (Agreal, Agradil) is a benzamide neuroleptic medicine indicated in the treatment of vasomotor symptoms associated with the menopause.
Verapamil, sold under various trade names, is a medication used for the treatment of high blood pressure, angina (chest pain from not enough blood flow to the heart), and supraventricular tachycardia.
Vernakalant (INN; codenamed RSD1235, proposed tradenames Kynapid and Brinavess) is an investigational drug under regulatory review for the acute conversion of atrial fibrillation.
Versed is a book of poetry written by Rae Armantrout and published by Wesleyan University Press in 2009 (see 2009 in poetry).
Verteporfin (trade name Visudyne), a benzoporphyrin derivative, is a medication used as a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration.
Verucerfont (GSK-561,679) is a drug developed by GlaxoSmithKline which acts as a CRF-1 antagonist.
Vesencumab is an immunomodulator designed for the treatment of solid malignancies.
Vesnarinone (INN) is a cardiotonic agent.
Vinblastine is a chemotherapy medication, typically used with other medications, to treat a number of types of cancer.
Zafirlukast is an orally administered leukotriene receptor antagonist (LTRA) used for the chronic treatment of asthma.