282 relations: Acetaldehyde dehydrogenase, Acetyl-CoA carboxylase, Acetylcholinesterase, Acid anhydride, Acid hydrolase, Acrosin, Adenosine deaminase, Adenosylmethionine hydrolase, Adenylyl cyclase, Alanine aminopeptidase, Alanine transaminase, Alcohol dehydrogenase, Aldehyde, Alkaline phosphatase, Alkenylglycerophosphocholine hydrolase, Alkenylglycerophosphoethanolamine hydrolase, Alkyl, Alpha-pinene-oxide decyclase, Amino-acid racemase, Aminolevulinic acid synthase, Amylase, Angiotensin-converting enzyme, Arginase, Argininosuccinate synthase, Aromatase, Aromatic L-amino acid decarboxylase, Aryl, Aspartate carbamoyltransferase, Aspartate transaminase, ATP synthase, ATPase, Benzenediol, Beta-carotene isomerase, Beta-galactosidase, Beta-lactamase, Biliverdin reductase, Bornyl diphosphate synthase, Butyrate kinase, Carbonic anhydrase, Carboxy-cis,cis-muconate cyclase, Catalase, Catechol oxidase, Catechol-O-methyltransferase, Ceruloplasmin, CGMP-specific phosphodiesterase type 5, Chalcone isomerase, Chitinase, Chloromuconate cycloisomerase, Cholesterol-5,6-oxide hydrolase, Choline acetyltransferase, ..., Cholinesterase, Chymotrypsin, Coenzyme Q – cytochrome c reductase, Copalyl diphosphate synthase, CTP synthetase, Cycloeucalenol cycloisomerase, Cyclophilin, CYP2D6, CYP2E1, CYP3A4, Cypridina-luciferin 2-monooxygenase, Cystathionine beta-lyase, Cystathionine gamma-lyase, Cytochrome, Cytochrome c oxidase, Cytochrome c peroxidase, Cytochrome P450, D-xylulose reductase, Dehydrogenase, Deiodinase, Deoxyribonuclease, Diacetyl reductase, Dichloromethane dehalogenase, Dichloromuconate cycloisomerase, Dihydrobenzophenanthridine oxidase, Dihydrofolate reductase, Disulfide, DMSO reductase, DNA ligase, DNA methyltransferase, DnaB helicase, Elastase, Endonuclease, Enoyl CoA isomerase, Ent-Copalyl diphosphate synthase, Ester, Ether, Exonuclease, Factor IX, Factor VII, Factor X, Factor XI, Factor XII, Factor XIII, Farnesol 2-isomerase, FARSB, Firefly luciferase, FKBP, FKBP10, FKBP1A, FKBP1B, FKBP2, FKBP3, FKBP5, FKBP52, FKBP6, FKBP8, FKBP9, FKBPL, Flavin group, Flavin prenyltransferase, Fructose 1,6-bisphosphatase, Fructose-bisphosphate aldolase, Furylfuramide isomerase, Gamma-glutamyltransferase, Glucose oxidase, Glutamine synthetase, Glutathione peroxidase, Glutathione reductase, Glutathione S-transferase, Glyceraldehyde 3-phosphate dehydrogenase, Glycerol dehydrogenase, Glycerol-3-phosphate dehydrogenase (NAD+), Glycosylase, GTP cyclohydrolase I, Guanylate cyclase, Halide, Halimadienyl-diphosphate synthase, Haloacetate dehalogenase, Halohydrin dehalogenase, Helicase, Heme, Hepoxilin-epoxide hydrolase, Histone methyltransferase, HMG-CoA reductase, Homoserine dehydrogenase, Hyaluronidase, Hydrolase, Hypoxanthine-guanine phosphoribosyltransferase, Inositol-3-phosphate synthase, International Union of Biochemistry and Molecular Biology, Intramolecular force, Iron–sulfur protein, Iron—cytochrome-c reductase, Isochorismatase, Isocitrate dehydrogenase, Isomerase, Ketone, Kynureninase, L-gulonolactone oxidase, L-xylulose reductase, Laccase, Lactase, Lactate dehydrogenase, Leukotriene C4 synthase, Leukotriene-A4 hydrolase, Ligase, Limonene-1,2-epoxide hydrolase, Linoleate isomerase, Lipoprotein lipase, List of EC numbers (EC 1), List of EC numbers (EC 2), List of EC numbers (EC 3), List of EC numbers (EC 4), List of EC numbers (EC 5), List of EC numbers (EC 6), Luciferase, Lyase, Lycopene beta-cyclase, Lycopene epsilon-cyclase, Lysozyme, Malate dehydrogenase, Maleate isomerase, Maleylacetoacetate isomerase, Maleylpyruvate isomerase, Maltase, Mandelate racemase, Matrix metalloproteinase, Metalloendopeptidase, Methyl group, Methylenetetrahydrofolate reductase, Methylmalonyl CoA epimerase, Methyltransferase, Microsomal epoxide hydrolase, Monoamine oxidase, Muconate lactonizing enzyme, Mutase, Myeloperoxidase, Na+/K+-ATPase, NADH dehydrogenase, Nicotinamide adenine dinucleotide, Nitrate reductase, Nitric oxide dioxygenase, Nitric oxide synthase, Nitrilase, Nitrite reductase, Nitrogen, Nitrogenase, Nuclease, Oplophorus-luciferin 2-monooxygenase, Ornithine decarboxylase, Ornithine transcarbamylase, Oxidoreductase, Oxoglutarate dehydrogenase complex, Oxygen, Parvulin, Pepsin, Peptide bond, Peroxidase, Peroxide, Phenylalanine ammonia-lyase, Phenylalanine hydroxylase, Phenylalanine racemase (ATP-hydrolysing), Phosphatase, Phosphoglucomutase, Phospholipase, Photoisomerase, Plasmepsin, Plasmin, Prolycopene isomerase, Prolyl endopeptidase, Prolyl isomerase, Propanediol-phosphate dehydrogenase, Prosolanapyrone-III cycloisomerase, Protease, Protein C, Protein disulfide-isomerase, Proteinase K, Protoporphyrinogen oxidase, Pyruvate carboxylase, Pyruvate dehydrogenase, Quinone, RecQ helicase, Renilla-luciferin 2-monooxygenase, Renin, Rennet, Restriction enzyme, Retinal isomerase, Retinol isomerase, Ribonuclease, Ribonuclease H, RuBisCO, S-adenosyl-L-homocysteine hydrolase, Sarcosine oxidase, Separase, Serine protease, Serine racemase, Steroid Delta-isomerase, Sucrase, Sulfite oxidase, Superoxide dismutase, Syn-copalyl-diphosphate synthase, Terpentedienyl-diphosphate synthase, Tetrahydroxypteridine cycloisomerase, Thiaminase, Thiamine oxidase, Thioredoxin reductase, Thrombin, Thyroid peroxidase, Tissue plasminogen activator, Topoisomerase, Trans-epoxysuccinate hydrolase, Transferase, Transglutaminase, Trypsin, Trypsinogen, Tryptophan synthase, Tyrosinase, Ubiquitin carboxy-terminal hydrolase L1, UDP-glucose 4-epimerase, Urate oxidase, Urease, Uridine monophosphate synthetase, Watasenia-luciferin 2-monooxygenase, Xanthine oxidase, Zeta-carotene isomerase, (R,R)-butanediol dehydrogenase, (S)-beta-macrocarpene synthase, 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase, 3-carboxy-cis,cis-muconate cycloisomerase, 4-Hydroxyphenylpyruvate dioxygenase, 6-carboxytetrahydropterin synthase. Expand index (232 more) » « Shrink index
Acetaldehyde dehydrogenases are dehydrogenase enzymes which catalyze the conversion of acetaldehyde into acetic acid.
Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT).
Acetylcholinesterase, encoded by HGNC gene ACHE; EC 184.108.40.206) is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
An acid anhydride is formed when two acid structures combine with loss of a water molecule.
An acid hydrolase (lysosomal acid lipase) is an enzyme that works best at acidic pHs.
Acrosin is a digestive enzyme that acts as a protease.
Adenosine deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme involved in purine metabolism.
In enzymology, an adenosylmethionine hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and H2O, whereas its two products are L-homoserine and methylthioadenosine.
Adenylyl cyclase (also commonly known as adenyl cyclase and adenylate cyclase, abbreviated AC) is an enzyme with key regulatory roles in essentially all cells.
Membrane alanyl aminopeptidase also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene.
Alanine transaminase (ALT) is a transaminase enzyme.
Alcohol dehydrogenases (ADH) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH).
An aldehyde or alkanal is an organic compound containing a functional group with the structure −CHO, consisting of a carbonyl center (a carbon double-bonded to oxygen) with the carbon atom also bonded to hydrogen and to an R group, which is any generic alkyl or side chain.
Alkaline phosphatase (ALP, ALKP, ALPase, Alk Phos) or basic phosphatase is a homodimeric protein enzyme of 86 kilodaltons.
In enzymology, an alkenylglycerophosphocholine hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphocholine and H2O, whereas its two products are aldehyde and sn-glycero-3-phosphocholine.
In enzymology, an alkenylglycerophosphoethanolamine hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine and H2O, whereas its two products are aldehyde and sn-glycero-3-phosphoethanolamine.
In organic chemistry, an alkyl substituent is an alkane missing one hydrogen.
In enzymology, an alpha-pinene-oxide decyclase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, alpha-pinene oxide, and one product, (Z)-2-methyl-5-isopropylhexa-2,5-dienal.
In enzymology, an amino-acid racemase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, L-amino acid, and one product, D-amino acid.
Aminolevulinic acid synthase (ALA synthase, ALAS, or delta-aminolevulinic acid synthase) is an enzyme that catalyzes the synthesis of D-aminolevulinic acid (ALA) the first common precursor in the biosynthesis of all tetrapyrroles such as hemes, cobalamins and chlorophylls.
An amylase is an enzyme that catalyses the hydrolysis of starch into sugars.
Angiotensin-converting enzyme, or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body.
Arginase (arginine amidinase, canavanase, L-arginase, arginine transamidinase) is a manganese-containing enzyme.
Argininosuccinate synthase or synthetase (ASS) is an enzyme that catalyzes the synthesis of argininosuccinate from citrulline and aspartate.
Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens.
Aromatic L-amino acid decarboxylase (AADC or AAAD), also known as DOPA decarboxylase (DDC), tryptophan decarboxylase, and 5-hydroxytryptophan decarboxylase, is a lyase enzyme.
In the context of organic molecules, aryl is any functional group or substituent derived from an aromatic ring, usually an aromatic hydrocarbon, such as phenyl and naphthyl.
Aspartate carbamoyltransferase (also known as aspartate transcarbamoylase or ATCase) catalyzes the first step in the pyrimidine biosynthetic pathway.
Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or serum glutamic oxaloacetic transaminase (SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme that was first described by Arthur Karmen and colleagues in 1954.
ATP synthase is an enzyme that creates the energy storage molecule adenosine triphosphate (ATP).
ATPases (adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5'-triphosphatase, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion.
Benzenediols or dihydroxybenzenes are organic chemical compounds in which two hydroxyl groups are substituted onto a benzene ring.
Beta-carotene isomerase (DWARF27 (gene)) is an enzyme with systematic name beta-carotene 9-cis-all-trans isomerase.
β-galactosidase, also called lactase, beta-gal or β-gal, is a glycoside hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides through the breaking of a glycosidic bond.
Beta-lactamases are enzymes produced by bacteria that provide multi-resistance to β-lactam antibiotics such as penicillins, cephalosporins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase.
Biliverdin reductase (BVR) is an enzyme found in all tissues under normal conditions, but especially in reticulo-macrophages of the liver and spleen.
In enzymology, bornyl diphosphate synthase (BPPS) is an enzyme that catalyzes the chemical reaction Bornyl diphosphate synthase is involved in the biosynthesis of the cyclic monoterpenoid bornyl diphosphate.
In enzymology, a butyrate kinase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ADP and butyryl-phosphate, whereas its two products are ATP and butyrate.
The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and protons).
In enzymology, a carboxy-cis,cis-muconate cyclase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate, and one product, 3-carboxy-cis,cis-muconate.
Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals).
Catechol oxidase is a copper oxidase that contains a type 3 di-copper cofactor and catalyzes the oxidation of ortho-diphenols into ortho-quinones coupled with the reduction of molecular oxygen to water.
Catechol-O-methyltransferase (COMT) is one of several enzymes that degrade catecholamines (such as dopamine, epinephrine, and norepinephrine), catecholestrogens, and various drugs and substances having a catechol structure.
Ceruloplasmin (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene.
cGMP-specific phosphodiesterase type 5 is an enzyme from the phosphodiesterase class.
In enzymology, a chalcone isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, a chalcone, and one product, a flavanone.
Chitinases (chitodextrinase, 1,4-beta-poly-N-acetylglucosaminidase, poly-beta-glucosaminidase, beta-1,4-poly-N-acetyl glucosamidinase, poly glycanohydrolase, (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase) are hydrolytic enzymes that break down glycosidic bonds in chitin.
In enzymology, a chloromuconate cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 2-chloro-2,5-dihydro-5-oxofuran-2-acetate, and one product, 3-chloro-cis,cis-muconate.
Cholesterol-5,6-oxide hydrolase (cholesterol-epoxide hydrolase, ChEH) is an enzyme with systematic name 5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase.
Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine.
In biochemistry, a cholinesterase or choline esterase is an esterase that lyses choline-based esters, several of which serve as neurotransmitters.
Chymotrypsin (chymotrypsins A and B, alpha-chymar ophth, avazyme, chymar, chymotest, enzeon, quimar, quimotrase, alpha-chymar, alpha-chymotrypsin A, alpha-chymotrypsin) is a digestive enzyme component of pancreatic juice acting in the duodenum, where it performs proteolysis, the breakdown of proteins and polypeptides.
The coenzyme Q: cytochrome c – oxidoreductase, sometimes called the cytochrome bc1 complex, and at other times complex III, is the third complex in the electron transport chain, playing a critical role in biochemical generation of ATP (oxidative phosphorylation).
In enzymology, a copalyl diphosphate synthase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, geranylgeranyl diphosphate, and one product, (+)-copalyl diphosphate.
CTP synthetase is an enzyme involved in pyrimidine biosynthesis that interconverts UTP and CTP.
In enzymology, a cycloeucalenol cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, cycloeucalenol, and one product, obtusifoliol.
Cyclophilins are a family of proteins from vertebrates and other organisms that bind to ciclosporin (cyclosporin A), an immunosuppressant which is usually used to suppress rejection after internal organ transplants.
Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.
Cytochrome P450 2E1 (abbreviated CYP2E1) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body.
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
In enzymology, a Cypridina-luciferin 2-monooxygenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are Cypridina luciferin and O2, whereas its 3 products are oxidized Cypridina luciferin, CO2, and light.
Cystathionine beta-lyase, also commonly referred to as CBL or β-cystathionase, is an enzyme that primarily catalyzes the following α,β-elimination reaction Thus, the substrate of this enzyme is L-cystathionine, whereas its 3 products are homocysteine, pyruvate, and ammonia.
Cystathionine gamma-lyase (CTH or CSE; also cystathionase) is an enzyme which breaks down cystathionine into cysteine, α-ketobutyrate, and ammonia.
Cytochromes are heme-containing proteins.
The enzyme cytochrome c oxidase or Complex IV, is a large transmembrane protein complex found in bacteria, archaea, and in eukaryotes in their mitochondria.
Cytochrome c peroxidase, or CCP, is a water-soluble heme-containing enzyme of the peroxidase family that takes reducing equivalents from cytochrome ''c'' and reduces hydrogen peroxide to water: CCP can be derived from aerobically grown yeast strains and can be isolated in both native and recombinant forms with high yield from Saccharomyces cerevisae. The enzyme’s primary function is to eliminate toxic radical molecules produced by the cell which are harmful to biological systems.
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
In enzymology, a D-xylulose reductase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are xylitol and NAD+, whereas its 3 products are D-xylulose, NADH, and H+.
A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN.
Deiodinase (or iodide peroxidase or "Monodeiodinase") is a peroxidase enzyme that is involved in the activation or deactivation of thyroid hormones.
A deoxyribonuclease (DNase, for short) is an enzyme that catalyzes the hydrolytic cleavage of phosphodiester linkages in the DNA backbone, thus degrading DNA.
Diacetyl reductase is the name of two acetoin forming enzymes.
Dichloromethane dehalogenase is a lyase enzyme that generates formaldehyde.
In enzymology, a dichloromuconate cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate, and one product, 2,4-dichloro-cis,cis-muconate.
Dihydrobenzophenanthridine oxidase (DHBP oxidase) is an enzyme.
Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.
In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.
DMSO reductase is a molybdenum-containing enzyme that catalyzes reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS).
DNA ligase is a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.
In biochemistry, the DNA methyltransferase (DNA MTase) family of enzymes catalyze the transfer of a methyl group to DNA.
DnaB helicase is an enzyme in bacteria which opens the replication fork during DNA replication.
In molecular biology, elastase is an enzyme from the class of proteases (peptidases) that break down proteins.
Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain.
Enoyl-CoA-(∆) isomerase, also known as dodecenoyl-CoA-(∆) isomerase, 3,2-trans-enoyl-CoA isomerase, ∆3(cis),∆2(trans)-enoyl-CoA isomerase, or acetylene-allene isomerase, is an enzyme that catalyzes the conversion of cis-or trans-double bonds of fatty acids at gamma-carbon (position 3) to trans double bonds at beta-carbon (position 2).
In enzymology, an ent-copalyl diphosphate synthase is an enzyme that catalyzes the chemical reaction: Hence, this enzyme has one substrate, geranylgeranyl pyrophosphate, and one product, ''ent''-copalyl pyrophosphate.
In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.
Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups.
Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain.
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1.
Factor VII (blood-coagulation factor VIIa, activated blood coagulation factor VII, formerly known as proconvertin) is one of the proteins that causes blood to clot in the coagulation cascade.
Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade.
Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade.
Coagulation factor XII, also known as Hageman factor, is a plasma protein.
Factor XIII or fibrin stabilizing factor is an enzyme of the blood coagulation system that crosslinks fibrin.
In enzymology, a farnesol 2-isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 2-trans,6-trans-farnesol, and one product, 2-cis,6-trans-farnesol.
Phenylalanyl-tRNA synthetase beta chain is an enzyme that in humans is encoded by the FARSB gene.
Firefly luciferase is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles.
FKBP, or FK506 binding protein, is a family of proteins that have prolyl isomerase activity and are related to the cyclophilins in function, though not in amino acid sequence.
FK506-binding protein 10 is a protein that in humans is encoded by the FKBP10 gene.
Peptidyl-prolyl cis-trans isomerase FKBP1A is an enzyme that in humans is encoded by the FKBP1A gene.
Peptidyl-prolyl cis-trans isomerase FKBP1B is an enzyme that in humans is encoded by the FKBP1B gene.
FK506-binding protein 2 is a protein that in humans is encoded by the FKBP2 gene.
FK506-binding protein 3 is a protein that in humans is encoded by the FKBP3 gene.
FK506 binding protein 5, also known as FKBP5, is a protein which in humans is encoded by the FKBP5 gene.
FK506-binding protein 4 is a protein that in humans is encoded by the FKBP4 gene.
FK506 binding protein 6, also known as FKBP6, is a human gene.
FK506-binding protein 8 is a protein that in humans is encoded by the FKBP8 gene.
FK506-binding protein 9 is a protein that in humans is encoded by the FKBP9 gene.
FK506-binding protein like, also known as FKBPL, is a protein that in humans is encoded by the FKBPL gene.
Flavin (from Latin flavus, "yellow") is the common name for a group of organic compounds based on pteridine, formed by the tricyclic heterocycle isoalloxazine.
Flavin prenyltransferase UbiX, that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD.
Fructose bisphosphatase is an enzyme that converts fructose-1,6-bisphosphate to fructose 6-phosphate in gluconeogenesis and the Calvin cycle which are both anabolic pathways.
Fructose-bisphosphate aldolase, often just aldolase, is an enzyme catalyzing a reversible reaction that splits the aldol, fructose 1,6-bisphosphate, into the triose phosphates dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P).
In enzymology, a furylfuramide isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide, and one product, (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.
Gamma-glutamyltransferase (also γ-glutamyltransferase, GGT, gamma-GT) is a transferase (a type of enzyme) that catalyzes the transfer of gamma-glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate).
The glucose oxidase enzyme (GOx) also known as notatin (EC number 220.127.116.11) is an oxido-reductase that catalyses the oxidation of glucose to hydrogen peroxide and D-glucono-δ-lactone.
Glutamine synthetase (GS) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine: Glutamate + ATP + NH3 → Glutamine + ADP + phosphate Glutamine Synthetase uses ammonia produced by nitrate reduction, amino acid degradation, and photorespiration.
Glutathione peroxidase (GPx) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage.
Glutathione reductase (GR) also known as glutathione-disulfide reductase (GSR) is an enzyme that in humans is encoded by the GSR gene.
Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification.
Glyceraldehyde 3-phosphate dehydrogenase (abbreviated as GAPDH or less commonly as G3PDH) is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules.
Glycerol dehydrogenase (also known as NAD+-linked glycerol dehydrogenase, glycerol: NAD+ 2-oxidoreductase, GDH, GlDH, GlyDH) is an enzyme in the oxidoreductase family that utilizes the NAD+ to catalyze the oxidation of glycerol to form glycerone (dihydroxyacetone).
In enzymology, a glycerol-3-phosphate dehydrogenase (NAD+) is an enzyme that catalyzes the chemical reaction The two substrates of this enzyme are sn-glycerol 3-phosphate and NAD+, whereas its 3 products are glycerone phosphate, NADH, and H+.
Glycosylases (EC 3.2) are enzymes that hydrolyze glycosyl compounds.
GTP cyclohydrolase I (GTPCH) is a member of the GTP cyclohydrolase family of enzymes.
Guanylate cyclase (also known as guanyl cyclase, guanylyl cyclase, or GC) is a lyase enzyme.
A halide is a binary phase, of which one part is a halogen atom and the other part is an element or radical that is less electronegative (or more electropositive) than the halogen, to make a fluoride, chloride, bromide, iodide, astatide, or theoretically tennesside compound.
Halimadienyl-diphosphate synthase (Rv3377c, halimadienyl diphosphate synthase, tuberculosinol diphosphate synthase, halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing)) is an enzyme with systematic name halima-5,13-dien-15-yl-diphosphate lyase (decyclizing).
In enzymology, a haloacetate dehalogenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are haloacetate and H2O, whereas its two products are glycolate and halide.
A halohydrin dehalogenase is an enzyme involved in the bacterial degradation of vicinal halohydrins.
Helicases are a class of enzymes vital to all living organisms.
Heme or haem is a coordination complex "consisting of an iron ion coordinated to a porphyrin acting as a tetradentate ligand, and to one or two axial ligands." The definition is loose, and many depictions omit the axial ligands.
In enzymology, a hepoxilin-epoxide hydrolase is an enzyme that catalyzes the conversion of the epoxyalcohol metabolites arachidonic acid, hepoxilin A3 and hepoxilin B3 to their tri-hydroxyl products, trioxolin A3 and trioxilin B3, respectively.
Histone methyltransferases (HMT) are histone-modifying enzymes (e.g., histone-lysine N-methyltransferases and histone-arginine N-methyltransferases), that catalyze the transfer of one, two, or three methyl groups to lysine and arginine residues of histone proteins.
HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, officially abbreviated HMGCR) is the rate-controlling enzyme (NADH-dependent,; NADPH-dependent) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids.
In enzymology, a homoserine dehydrogenase is an enzyme that catalyzes the chemical reaction The 2 substrates of this enzyme are L-homoserine and NAD+ (or NADP+), whereas its 3 products are L-aspartate 4-semialdehyde, NADH (or NADPH), and H+.
Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid (HA).
Hydrolase is a class of enzyme that is commonly used as biochemical catalysts that utilize water to break a chemical bond.
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene.
In enzymology, an inositol-3-phosphate synthase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, D-glucose 6-phosphate, and one product, 1D-myo-inositol 3-phosphate.
The International Union of Biochemistry and Molecular Biology (IUBMB) is an international non-governmental organisation concerned with biochemistry and molecular biology.
An intramolecular force is any force that binds together the atoms making up a molecule or compound, not to be confused with intermolecular forces, which are the forces present between molecules.
Iron–sulfur proteins are proteins characterized by the presence of iron–sulfur clusters containing sulfide-linked di-, tri-, and tetrairon centers in variable oxidation states.
In enzymology, an iron—cytochrome-c reductase (created 1972 as, transferred 2014 to) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ferrocytochrome c and Fe3+, whereas its two products are ferricytochrome c and Fe2+.
In enzymology, an isochorismatase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are isochorismate and H2O, whereas its two products are 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate.
Isocitrate dehydrogenase (IDH) and is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2.
Isomerases are a general class of enzymes that convert a molecule from one isomer to another.
In chemistry, a ketone (alkanone) is an organic compound with the structure RC(.
Kynureninase or L-Kynurenine hydrolase (KYNU) is a PLP dependent enzyme that catalyses the cleavage of kynurenine (Kyn) into anthranilic acid (Ant).
L-gulonolactone oxidase (EC) is an enzyme that produces vitamin C, but is non-functional in Haplorrhini (including humans), in some bats, and in guinea pigs.
Dicarbonyl/L-xylulose reductase, also known as carbonyl reductase II, is an enzyme that in human is encoded by the DCXR gene located on chromosome 17.
Laccases are copper-containing oxidase enzymes found in many plants, fungi, and microorganisms.
Lactase is an enzyme produced by many organisms.
Lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells (animals, plants, and prokaryotes).
Leukotriene C4 synthase is an enzyme that in humans is encoded by the LTC4S gene.
Leukotriene A4 hydrolase, also known as LTA4H is a human gene.
In biochemistry, a ligase is an enzyme that can catalyze the joining of two large molecules by forming a new chemical bond, usually with accompanying hydrolysis of a small pendant chemical group on one of the larger molecules or the enzyme catalyzing the linking together of two compounds, e.g., enzymes that catalyze joining of C-O, C-S, C-N, etc.
In enzymology, a limonene-1,2-epoxide hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are limonene-1,2-epoxide and H2O, whereas its product is limonene-1,2-diol.
In enzymology, a linoleate isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 9-cis,12-cis-octadecadienoate, and one product, 9-cis,11-trans-octadecadienoate.
Lipoprotein lipase (LPL) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase.
This list contains a list of EC numbers for the first group, EC 1, oxidoreductases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
This list contains a list of EC numbers for the fifth group, EC 5, isomerases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
This list contains a list of EC numbers for the sixth group, EC 6, ligases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
Luciferase is a generic term for the class of oxidative enzymes that produce bioluminescence, and is usually distinguished from a photoprotein.
In biochemistry, a lyase is an enzyme that catalyzes the breaking (an "elimination" reaction) of various chemical bonds by means other than hydrolysis (a "substitution" reaction) and oxidation, often forming a new double bond or a new ring structure.
Lycopene beta-cyclase (CrtL, CrtL-b, CrtY) is an enzyme with systematic name carotenoid beta-end group lyase (decyclizing).
Lycopene epsilon-cyclase (CrtL-e, LCYe) is an enzyme with systematic name carotenoid psi-end group lyase (decyclizing).
Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase is an antimicrobial enzyme produced by animals that forms part of the innate immune system.
Malate dehydrogenase (MDH) is an enzyme that reversibly catalyzes the oxidation of malate to oxaloacetate using the reduction of NAD+ to NADH.
In enzymology, a maleate isomerase, or maleate cis-tran isomerase, is a member of the Asp/Glu racemase superfamily discovered in bacteria.
In enzymology, a maleylacetoacetate isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 4-maleylacetoacetate, and one product, 4-fumarylacetoacetate.
In enzymology, a maleylpyruvate isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 3-maleylpyruvate, and one product, 3-fumarylpyruvate.
Maltase (alpha-glucosidase, glucoinvertase, glucosidosucrase, maltase-glucoamylase, alpha-glucopyranosidase, glucosidoinvertase, alpha-D-glucosidase, alpha-glucoside hydrolase, alpha-1,4-glucosidase, alpha-D-glucoside glucohydrolase) is an enzyme located in on the brush border of the small intestine that breaks down the disaccharide maltose.
Mandelate racemase is a bacterial enzyme which catalyzes the interconversion of the enantiomers of mandelate via an enol intermediate.
Matrix metalloproteinases (MMPs), also known as matrixins, are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins.
A metalloendopeptidase is an enzyme that functions as a metalloproteinase endopeptidase.
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.
Methylene tetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene.
Methylmalonyl CoA epimerase (methylmalonyl-CoA racemase, methylmalonyl coenzyme A racemase, DL-methylmalonyl-CoA racemase, 2-methyl-3-oxopropanoyl-CoA 2-epimerase) is an enzyme involved in fatty acid catabolism that is encoded in human by the "MCEE" gene located on chromosome 2.
Methyltransferases are a large group of enzymes that all methylate their substrates but can be split into several subclasses based on their structural features.
In enzymology, a microsomal epoxide hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are cis-stilbene oxide and H2O, whereas its product is (+)-(1R,2R)-1,2-diphenylethane-1,2-diol.
L-Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines.
Muconate lactonizing enzymes (muconate cycloisomerase I, cis,cis-muconate-lactonizing enzyme, cis,cis-muconate cycloisomerase, 4-carboxymethyl-4-hydroxyisocrotonolactone lyase (decyclizing), CatB, MCI, MLE, 2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)) are involved in the breakdown of lignin-derived aromatics, catechol and protocatechuate, to citric acid cycle intermediates as a part of the β-ketoadipate pathway in soil microbes.
A mutase is an enzyme of the isomerase class that catalyzes the shifting of a functional group from one position to another within the same molecule.
Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene on chromosome 17.
-ATPase (sodium-potassium adenosine triphosphatase, also known as the pump or sodium–potassium pump) is an enzyme (an electrogenic transmembrane ATPase) found in the plasma membrane of all animal cells.
NADH dehydrogenase (cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase, dihydrocodehydrogenase I dehydrogenase, dihydronicotinamide adenine dinucleotide dehydrogenase, diphosphopyridine diaphorase, DPNH diaphorase, NADH diaphorase, NADH hydrogenase, NADH oxidoreductase, NADH-menadione oxidoreductase, reduced diphosphopyridine nucleotide diaphorase) is an enzyme with systematic name NADH:acceptor oxidoreductase.
Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells.
Nitrate reductases are molybdoenzymes that reduce nitrate (NO) to nitrite (NO).
Nitric oxide dioxygenase is an enzyme that catalyzes the conversion of nitric oxide (NO) to nitrate (NO).
Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine.
Nitrilase enzymes (nitrile aminohydrolase) catalyse the hydrolysis of nitriles to carboxylic acids and ammonia, without the formation of "free" amide intermediates.
Nitrite reductase refers to any of several classes of enzymes that catalyze the reduction of nitrite.
Nitrogen is a chemical element with symbol N and atomic number 7.
Nitrogenases are enzymes that are produced by certain bacteria, such as cyanobacteria (blue-green algae).
A nuclease (also archaically known as nucleodepolymerase or polynucleotidase) is an enzyme capable of cleaving the phosphodiester bonds between monomers of nucleic acids.
In enzymology, an Oplophorus-luciferin 2-monooxygenase is a luciferase, an enzyme, from the deep-sea shrimp Oplophorus gracilirostris that catalyzes the chemical reaction: Thus, the two substrates of this enzyme are the luciferin, Coelenterazine and O2, whereas its 3 products are the oxyluciferin, Coelenteramide, CO2, and light.
The enzyme ornithine decarboxylase (ODC) catalyzes the decarboxylation of ornithine (a product of the urea cycle) to form putrescine.
Ornithine transcarbamylase (OTC) (also called ornithine carbamoyltransferase) is an enzyme that catalyzes the reaction between carbamoyl phosphate (CP) and ornithine (Orn) to form citrulline (Cit) and phosphate (Pi).
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor.
The oxoglutarate dehydrogenase complex (OGDC) or α-ketoglutarate dehydrogenase complex is an enzyme complex, most commonly known for its role in the citric acid cycle.
Oxygen is a chemical element with symbol O and atomic number 8.
Parvulin, a 92-amino acid protein discovered in E. coli in 1994,Rahfeld JU, Schierhorn A, Mann KH.
Pepsin is an endopeptidase that breaks down proteins into smaller peptides (that is, a protease).
A peptide bond is a covalent chemical bond linking two consecutive amino acid monomers along a peptide or protein chain.
Peroxidases (EC number) are a large family of enzymes that typically catalyze a reaction of the form: For many of these enzymes the optimal substrate is hydrogen peroxide, but others are more active with organic hydroperoxides such as lipid peroxides.
Peroxide is a compound with the structure R-O-O-R. The O−O group in a peroxide is called the peroxide group or peroxo group.
Phenylalanine ammonia lyase is an enzyme that catalyzes a reaction converting L-phenylalanine to ammonia and ''trans''-cinnamic acid.
Phenylalanine hydroxylase (PAH) is an enzyme that catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine.
The enzyme phenylalanine racemase (phenylalanine racemase, phenylalanine racemase (adenosine triphosphate-hydrolysing), gramicidin S synthetase I) is the enzyme that acts on amino acids and derivatives.
A phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol.
Phosphoglucomutase is an enzyme that transfers a phosphate group on an α-D-glucose monomer from the 1' to the 6' position in the forward direction or the 6' to the 1' position in the reverse direction.
A phospholipase is an enzyme that hydrolyzes phospholipids into fatty acids and other lipophilic substances.
A photoisomerase is a protein in the eye that is responsible for isomerizing photopigments.
Plasmepsins are a class of at least 10 enzymes (and) produced by the Plasmodium falciparum parasite.
Plasmin is an important enzyme present in blood that degrades many blood plasma proteins, including fibrin clots.
Prolycopene isomerase (CRTISO, carotene cis-trans isomerase, ZEBRA2 (gene), carotene isomerase, carotenoid isomerase) is an enzyme with systematic name 7,9,7',9'-tetracis-lycopene cis-trans-isomerase.
Prolyl endopeptidase (PE) also known as prolyl oligopeptidase or post-proline cleaving enzyme is an enzyme that in humans is encoded by the PREP gene.
Prolyl isomerase (also known as peptidylprolyl isomerase or PPIase) is an enzyme found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline.
In enzymology, a propanediol-phosphate dehydrogenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD+, whereas its 3 products are hydroxyacetone phosphate, NADH, and H+.
Prosolanapyrone-III cycloisomerase (Sol5, SPS, solanapyrone synthase (bifunctional enzyme: prosolanapyrone II oxidase/prosolanapyrone III cyclosiomerase)) is an enzyme with systematic name prosolanapyrone-III:(-)-solanapyrone A isomerase.
A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.
Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, is a zymogen, the activated form of which plays an important role in regulating anticoagulation, inflammation, cell death, and maintaining the permeability of blood vessel walls in humans and other animals.
Protein disulfide isomerase, or PDI, is an enzyme in the endoplasmic reticulum (ER) in eukaryotes and the periplasm of bacteria that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold.
In molecular biology Proteinase K (protease K, endopeptidase K, Tritirachium alkaline proteinase, Tritirachium album serine proteinase, Tritirachium album proteinase K) is a broad-spectrum serine protease.
Protoporphyrinogen oxidase is an enzyme that in humans is encoded by the PPOX gene.
Pyruvate carboxylase (PC) encoded by the gene PC is an enzyme of the ligase class that catalyzes (depending on the species) the physiologically irreversible carboxylation of pyruvate to form oxaloacetate (OAA).
Pyruvate dehydrogenase is the first component enzyme of pyruvate dehydrogenase complex (PDC).
The quinones are a class of organic compounds that are formally "derived from aromatic compounds by conversion of an even number of –CH.
RecQ helicase is a family of helicase enzymes initially found in Escherichia coli that has been shown to be important in genome maintenance.
Renilla-luciferin 2-monooxygenase, Renilla luciferase, or RLuc, is a bioluminescent enzyme found in Renilla reniformis, belonging to a group of coelenterazine luciferases.
Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that mediates the volume of extracellular fluid (blood plasma, lymph and interstitial fluid), and arterial vasoconstriction.
Rennet is a complex set of enzymes produced in the stomachs of ruminant mammals.
A restriction enzyme or restriction endonuclease is an enzyme that cleaves DNA into fragments at or near specific recognition sites within the molecule known as restriction sites.
In enzymology, a retinal isomerase is an enzyme that catalyzes the isomerisation of trans Retinal in eye into 11-cis-retinal which is form suitable to bind with protein opsin.
In enzymology, a retinol isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, all-trans-retinol, and one product, 11-cis-retinol.
Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components.
Ribonuclease H (abbreviated RNase H or RNH) is a family of non-sequence-specific endonuclease enzymes that catalyze the cleavage of RNA in an RNA/DNA substrate via a hydrolytic mechanism.
Ribulose-1,5-bisphosphate carboxylase/oxygenase, commonly known by the abbreviations RuBisCO, RuBPCase, or RuBPco, is an enzyme involved in the first major step of carbon fixation, a process by which atmospheric carbon dioxide is converted by plants and other photosynthetic organisms to energy-rich molecules such as glucose.
S-adenosyl-L-homocysteine hydrolase (AdoHcyase) is an enzyme of the activated methyl cycle, responsible for the reversible hydration of S-adenosyl-L-homocysteine into adenosine and homocysteine.
Sarcosine oxidase is an enzyme that catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, 5,10-CH2-tetrahydrofolate in a reaction requiring H4-tetrahydrofolate and oxygen.
Separase, also known as separin, is a cysteine protease responsible for triggering anaphase by hydrolysing cohesin, which is the protein responsible for binding sister chromatids during the early stage of anaphase.
Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins, in which serine serves as the nucleophilic amino acid at the (enzyme's) active site.
Serine racemase is an enzyme which generates D-serine from L-serine.
In enzymology, a steroid Δ5-isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, a 3-oxo-Δ5-steroid, and one product, a 3-oxo-Δ4-steroid.
Sucrase is a digestive enzyme secreted in the small intestine.
Sulfite oxidase is an enzyme in the mitochondria of all eukaryotes.
Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2&minus) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2).
Syn-copalyl-diphosphate synthase (OsCyc1, OsCPSsyn, syn-CPP synthase, syn-copalyl diphosphate synthase) is an enzyme with systematic name 9alpha-copalyl-diphosphate lyase (decyclizing).
Terpentedienyl-diphosphate synthase (terpentedienol diphosphate synthase, Cyc1, clerodadienyl diphosphate synthase) is an enzyme with systematic name terpentedienyl-diphosphate lyase (decyclizing).
In enzymology, a tetrahydroxypteridine cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, tetrahydroxypteridine, and one product, xanthine-8-carboxylate.
Thiaminase is an enzyme that metabolizes or breaks down thiamine into two molecular parts.
In enzymology, a thiamine oxidase is an enzyme that catalyzes the chemical reaction The 3 substrates of this enzyme are thiamine, O2, and H2O, whereas its two products are thiamine acetic acid and H2O2.
Thioredoxin reductases (TR, TrxR) are the only known enzymes to reduce thioredoxin (Trx).
Thrombin (fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene.
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid.
Tissue plasminogen activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots.
Topoisomerases are enzymes that participate in the overwinding or underwinding of DNA.
In enzymology, a trans-epoxysuccinate hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are trans-2,3-epoxysuccinate and H2O, whereas its product is meso-tartrate.
A transferase is any one of a class of enzymes that enact the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor).
A transglutaminase is an enzyme that catalyzes the formation of an isopeptide bond between a free amine group (e.g., protein- or peptide-bound lysine) and the acyl group at the end of the side chain of protein- or peptide-bound glutamine.
Trypsin is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyzes proteins.
Trypsinogen (EC 18.104.22.168/20/21/23/24/26) is the precursor form or zymogen of trypsin, a digestive enzyme.
Tryptophan synthase or tryptophan synthetase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan.
Tyrosinase is an oxidase that is the rate-limiting enzyme for controlling the production of melanin.
Ubiquitin carboxy-terminal hydrolase L1 (ubiquitin C-terminal hydrolase, UCH-L1) is a deubiquitinating enzyme.
The enzyme UDP-glucose 4-epimerase, also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells.
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate.
Ureases, functionally, belong to the superfamily of amidohydrolases and phosphotriesterases.
Uridine monophosphate synthase (UMPS) (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) is the enzyme that catalyses the formation of uridine monophosphate (UMP), an energy-carrying molecule in many important biosynthetic pathways.
In enzymology, a Watasenia-luciferin 2-monooxygenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are Watasenia luciferin and O2, whereas its 3 products are oxidized Watasenia luciferin, CO2, and hn.
Xanthine oxidase (XO, sometimes XAO) is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species.
Zeta-carotene isomerase (Z-ISO, 15-cis-zeta-carotene isomerase) is an enzyme with systematic name 9,15,9'-tricis-zeta-carotene cis-trans-isomerase.
In enzymology, a (R,R)-butanediol dehydrogenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are (R,R)-butane-2,3-diol and NAD+, whereas its 3 products are (R)-acetoin, NADH, and H+.
(S)-beta-macrocarpene synthase (TPS6, TPS11) is an enzyme with systematic name (S)-beta-macrocarpene lyase (decyclizing).
In enzymology, a 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide, and one product, trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.
In enzymology, a 3-carboxy-cis,cis-muconate cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate, and one product, cis,cis-butadiene-1,2,4-tricarboxylate.
4-Hydroxyphenylpyruvate dioxygenase (HPPD), also known as α-ketoisocaproate dioxygenase (KIC dioxygenase), is an Fe(II)-containing non-heme oxygenase that catalyzes the second reaction in the catabolism of tyrosine - the conversion of 4-hydroxyphenylpyruvate into homogentisate.
6-carboxytetrahydropterin synthase (CPH4 synthase, queD (gene), ToyB, ykvK (gene)) is an enzyme with systematic name 7,8-dihydroneopterin 3'-triphosphate acetaldehyde-lyase (6-carboxy-5,6,7,8-tetrahydropterin and triphosphate-forming).