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List of enzymes

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This page lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission numbering system. [1]

282 relations: Acetaldehyde dehydrogenase, Acetyl-CoA carboxylase, Acetylcholinesterase, Acid anhydride, Acid hydrolase, Acrosin, Adenosine deaminase, Adenosylmethionine hydrolase, Adenylyl cyclase, Alanine aminopeptidase, Alanine transaminase, Alcohol dehydrogenase, Aldehyde, Alkaline phosphatase, Alkenylglycerophosphocholine hydrolase, Alkenylglycerophosphoethanolamine hydrolase, Alkyl, Alpha-pinene-oxide decyclase, Amino-acid racemase, Aminolevulinic acid synthase, Amylase, Angiotensin-converting enzyme, Arginase, Argininosuccinate synthase, Aromatase, Aromatic L-amino acid decarboxylase, Aryl, Aspartate carbamoyltransferase, Aspartate transaminase, ATP synthase, ATPase, Benzenediol, Beta-carotene isomerase, Beta-galactosidase, Beta-lactamase, Biliverdin reductase, Bornyl diphosphate synthase, Butyrate kinase, Carbonic anhydrase, Carboxy-cis,cis-muconate cyclase, Catalase, Catechol oxidase, Catechol-O-methyltransferase, Ceruloplasmin, CGMP-specific phosphodiesterase type 5, Chalcone isomerase, Chitinase, Chloromuconate cycloisomerase, Cholesterol-5,6-oxide hydrolase, Choline acetyltransferase, ..., Cholinesterase, Chymotrypsin, Coenzyme Q – cytochrome c reductase, Copalyl diphosphate synthase, CTP synthetase, Cycloeucalenol cycloisomerase, Cyclophilin, CYP2D6, CYP2E1, CYP3A4, Cypridina-luciferin 2-monooxygenase, Cystathionine beta-lyase, Cystathionine gamma-lyase, Cytochrome, Cytochrome c oxidase, Cytochrome c peroxidase, Cytochrome P450, D-xylulose reductase, Dehydrogenase, Deiodinase, Deoxyribonuclease, Diacetyl reductase, Dichloromethane dehalogenase, Dichloromuconate cycloisomerase, Dihydrobenzophenanthridine oxidase, Dihydrofolate reductase, Disulfide, DMSO reductase, DNA ligase, DNA methyltransferase, DnaB helicase, Elastase, Endonuclease, Enoyl CoA isomerase, Ent-Copalyl diphosphate synthase, Ester, Ether, Exonuclease, Factor IX, Factor VII, Factor X, Factor XI, Factor XII, Factor XIII, Farnesol 2-isomerase, FARSB, Firefly luciferase, FKBP, FKBP10, FKBP1A, FKBP1B, FKBP2, FKBP3, FKBP5, FKBP52, FKBP6, FKBP8, FKBP9, FKBPL, Flavin group, Flavin prenyltransferase, Fructose 1,6-bisphosphatase, Fructose-bisphosphate aldolase, Furylfuramide isomerase, Gamma-glutamyltransferase, Glucose oxidase, Glutamine synthetase, Glutathione peroxidase, Glutathione reductase, Glutathione S-transferase, Glyceraldehyde 3-phosphate dehydrogenase, Glycerol dehydrogenase, Glycerol-3-phosphate dehydrogenase (NAD+), Glycosylase, GTP cyclohydrolase I, Guanylate cyclase, Halide, Halimadienyl-diphosphate synthase, Haloacetate dehalogenase, Halohydrin dehalogenase, Helicase, Heme, Hepoxilin-epoxide hydrolase, Histone methyltransferase, HMG-CoA reductase, Homoserine dehydrogenase, Hyaluronidase, Hydrolase, Hypoxanthine-guanine phosphoribosyltransferase, Inositol-3-phosphate synthase, International Union of Biochemistry and Molecular Biology, Intramolecular force, Iron–sulfur protein, Iron—cytochrome-c reductase, Isochorismatase, Isocitrate dehydrogenase, Isomerase, Ketone, Kynureninase, L-gulonolactone oxidase, L-xylulose reductase, Laccase, Lactase, Lactate dehydrogenase, Leukotriene C4 synthase, Leukotriene-A4 hydrolase, Ligase, Limonene-1,2-epoxide hydrolase, Linoleate isomerase, Lipoprotein lipase, List of EC numbers (EC 1), List of EC numbers (EC 2), List of EC numbers (EC 3), List of EC numbers (EC 4), List of EC numbers (EC 5), List of EC numbers (EC 6), Luciferase, Lyase, Lycopene beta-cyclase, Lycopene epsilon-cyclase, Lysozyme, Malate dehydrogenase, Maleate isomerase, Maleylacetoacetate isomerase, Maleylpyruvate isomerase, Maltase, Mandelate racemase, Matrix metalloproteinase, Metalloendopeptidase, Methyl group, Methylenetetrahydrofolate reductase, Methylmalonyl CoA epimerase, Methyltransferase, Microsomal epoxide hydrolase, Monoamine oxidase, Muconate lactonizing enzyme, Mutase, Myeloperoxidase, Na+/K+-ATPase, NADH dehydrogenase, Nicotinamide adenine dinucleotide, Nitrate reductase, Nitric oxide dioxygenase, Nitric oxide synthase, Nitrilase, Nitrite reductase, Nitrogen, Nitrogenase, Nuclease, Oplophorus-luciferin 2-monooxygenase, Ornithine decarboxylase, Ornithine transcarbamylase, Oxidoreductase, Oxoglutarate dehydrogenase complex, Oxygen, Parvulin, Pepsin, Peptide bond, Peroxidase, Peroxide, Phenylalanine ammonia-lyase, Phenylalanine hydroxylase, Phenylalanine racemase (ATP-hydrolysing), Phosphatase, Phosphoglucomutase, Phospholipase, Photoisomerase, Plasmepsin, Plasmin, Prolycopene isomerase, Prolyl endopeptidase, Prolyl isomerase, Propanediol-phosphate dehydrogenase, Prosolanapyrone-III cycloisomerase, Protease, Protein C, Protein disulfide-isomerase, Proteinase K, Protoporphyrinogen oxidase, Pyruvate carboxylase, Pyruvate dehydrogenase, Quinone, RecQ helicase, Renilla-luciferin 2-monooxygenase, Renin, Rennet, Restriction enzyme, Retinal isomerase, Retinol isomerase, Ribonuclease, Ribonuclease H, RuBisCO, S-adenosyl-L-homocysteine hydrolase, Sarcosine oxidase, Separase, Serine protease, Serine racemase, Steroid Delta-isomerase, Sucrase, Sulfite oxidase, Superoxide dismutase, Syn-copalyl-diphosphate synthase, Terpentedienyl-diphosphate synthase, Tetrahydroxypteridine cycloisomerase, Thiaminase, Thiamine oxidase, Thioredoxin reductase, Thrombin, Thyroid peroxidase, Tissue plasminogen activator, Topoisomerase, Trans-epoxysuccinate hydrolase, Transferase, Transglutaminase, Trypsin, Trypsinogen, Tryptophan synthase, Tyrosinase, Ubiquitin carboxy-terminal hydrolase L1, UDP-glucose 4-epimerase, Urate oxidase, Urease, Uridine monophosphate synthetase, Watasenia-luciferin 2-monooxygenase, Xanthine oxidase, Zeta-carotene isomerase, (R,R)-butanediol dehydrogenase, (S)-beta-macrocarpene synthase, 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase, 3-carboxy-cis,cis-muconate cycloisomerase, 4-Hydroxyphenylpyruvate dioxygenase, 6-carboxytetrahydropterin synthase. Expand index (232 more) »

Acetaldehyde dehydrogenase

Acetaldehyde dehydrogenases are dehydrogenase enzymes which catalyze the conversion of acetaldehyde into acetic acid.

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Acetyl-CoA carboxylase

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT).

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Acetylcholinesterase

Acetylcholinesterase, encoded by HGNC gene ACHE; EC 3.1.1.7) is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

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Acid anhydride

An acid anhydride is formed when two acid structures combine with loss of a water molecule.

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Acid hydrolase

An acid hydrolase (lysosomal acid lipase) is an enzyme that works best at acidic pHs.

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Acrosin

Acrosin is a digestive enzyme that acts as a protease.

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Adenosine deaminase

Adenosine deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme involved in purine metabolism.

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Adenosylmethionine hydrolase

In enzymology, an adenosylmethionine hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and H2O, whereas its two products are L-homoserine and methylthioadenosine.

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Adenylyl cyclase

Adenylyl cyclase (also commonly known as adenyl cyclase and adenylate cyclase, abbreviated AC) is an enzyme with key regulatory roles in essentially all cells.

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Alanine aminopeptidase

Membrane alanyl aminopeptidase also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene.

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Alanine transaminase

Alanine transaminase (ALT) is a transaminase enzyme.

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Alcohol dehydrogenase

Alcohol dehydrogenases (ADH) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH).

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Aldehyde

An aldehyde or alkanal is an organic compound containing a functional group with the structure −CHO, consisting of a carbonyl center (a carbon double-bonded to oxygen) with the carbon atom also bonded to hydrogen and to an R group, which is any generic alkyl or side chain.

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Alkaline phosphatase

Alkaline phosphatase (ALP, ALKP, ALPase, Alk Phos) or basic phosphatase is a homodimeric protein enzyme of 86 kilodaltons.

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Alkenylglycerophosphocholine hydrolase

In enzymology, an alkenylglycerophosphocholine hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphocholine and H2O, whereas its two products are aldehyde and sn-glycero-3-phosphocholine.

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Alkenylglycerophosphoethanolamine hydrolase

In enzymology, an alkenylglycerophosphoethanolamine hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine and H2O, whereas its two products are aldehyde and sn-glycero-3-phosphoethanolamine.

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Alkyl

In organic chemistry, an alkyl substituent is an alkane missing one hydrogen.

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Alpha-pinene-oxide decyclase

In enzymology, an alpha-pinene-oxide decyclase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, alpha-pinene oxide, and one product, (Z)-2-methyl-5-isopropylhexa-2,5-dienal.

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Amino-acid racemase

In enzymology, an amino-acid racemase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, L-amino acid, and one product, D-amino acid.

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Aminolevulinic acid synthase

Aminolevulinic acid synthase (ALA synthase, ALAS, or delta-aminolevulinic acid synthase) is an enzyme that catalyzes the synthesis of D-aminolevulinic acid (ALA) the first common precursor in the biosynthesis of all tetrapyrroles such as hemes, cobalamins and chlorophylls.

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Amylase

An amylase is an enzyme that catalyses the hydrolysis of starch into sugars.

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Angiotensin-converting enzyme

Angiotensin-converting enzyme, or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body.

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Arginase

Arginase (arginine amidinase, canavanase, L-arginase, arginine transamidinase) is a manganese-containing enzyme.

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Argininosuccinate synthase

Argininosuccinate synthase or synthetase (ASS) is an enzyme that catalyzes the synthesis of argininosuccinate from citrulline and aspartate.

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Aromatase

Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens.

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Aromatic L-amino acid decarboxylase

Aromatic L-amino acid decarboxylase (AADC or AAAD), also known as DOPA decarboxylase (DDC), tryptophan decarboxylase, and 5-hydroxytryptophan decarboxylase, is a lyase enzyme.

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Aryl

In the context of organic molecules, aryl is any functional group or substituent derived from an aromatic ring, usually an aromatic hydrocarbon, such as phenyl and naphthyl.

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Aspartate carbamoyltransferase

Aspartate carbamoyltransferase (also known as aspartate transcarbamoylase or ATCase) catalyzes the first step in the pyrimidine biosynthetic pathway.

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Aspartate transaminase

Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or serum glutamic oxaloacetic transaminase (SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme that was first described by Arthur Karmen and colleagues in 1954.

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ATP synthase

ATP synthase is an enzyme that creates the energy storage molecule adenosine triphosphate (ATP).

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ATPase

ATPases (adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5'-triphosphatase, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion.

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Benzenediol

Benzenediols or dihydroxybenzenes are organic chemical compounds in which two hydroxyl groups are substituted onto a benzene ring.

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Beta-carotene isomerase

Beta-carotene isomerase (DWARF27 (gene)) is an enzyme with systematic name beta-carotene 9-cis-all-trans isomerase.

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Beta-galactosidase

β-galactosidase, also called lactase, beta-gal or β-gal, is a glycoside hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides through the breaking of a glycosidic bond.

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Beta-lactamase

Beta-lactamases are enzymes produced by bacteria that provide multi-resistance to β-lactam antibiotics such as penicillins, cephalosporins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase.

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Biliverdin reductase

Biliverdin reductase (BVR) is an enzyme found in all tissues under normal conditions, but especially in reticulo-macrophages of the liver and spleen.

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Bornyl diphosphate synthase

In enzymology, bornyl diphosphate synthase (BPPS) is an enzyme that catalyzes the chemical reaction Bornyl diphosphate synthase is involved in the biosynthesis of the cyclic monoterpenoid bornyl diphosphate.

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Butyrate kinase

In enzymology, a butyrate kinase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ADP and butyryl-phosphate, whereas its two products are ATP and butyrate.

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Carbonic anhydrase

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and protons).

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Carboxy-cis,cis-muconate cyclase

In enzymology, a carboxy-cis,cis-muconate cyclase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate, and one product, 3-carboxy-cis,cis-muconate.

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Catalase

Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals).

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Catechol oxidase

Catechol oxidase is a copper oxidase that contains a type 3 di-copper cofactor and catalyzes the oxidation of ortho-diphenols into ortho-quinones coupled with the reduction of molecular oxygen to water.

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Catechol-O-methyltransferase

Catechol-O-methyltransferase (COMT) is one of several enzymes that degrade catecholamines (such as dopamine, epinephrine, and norepinephrine), catecholestrogens, and various drugs and substances having a catechol structure.

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Ceruloplasmin

Ceruloplasmin (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene.

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CGMP-specific phosphodiesterase type 5

cGMP-specific phosphodiesterase type 5 is an enzyme from the phosphodiesterase class.

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Chalcone isomerase

In enzymology, a chalcone isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, a chalcone, and one product, a flavanone.

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Chitinase

Chitinases (chitodextrinase, 1,4-beta-poly-N-acetylglucosaminidase, poly-beta-glucosaminidase, beta-1,4-poly-N-acetyl glucosamidinase, poly glycanohydrolase, (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase) are hydrolytic enzymes that break down glycosidic bonds in chitin.

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Chloromuconate cycloisomerase

In enzymology, a chloromuconate cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 2-chloro-2,5-dihydro-5-oxofuran-2-acetate, and one product, 3-chloro-cis,cis-muconate.

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Cholesterol-5,6-oxide hydrolase

Cholesterol-5,6-oxide hydrolase (cholesterol-epoxide hydrolase, ChEH) is an enzyme with systematic name 5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase.

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Choline acetyltransferase

Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine.

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Cholinesterase

In biochemistry, a cholinesterase or choline esterase is an esterase that lyses choline-based esters, several of which serve as neurotransmitters.

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Chymotrypsin

Chymotrypsin (chymotrypsins A and B, alpha-chymar ophth, avazyme, chymar, chymotest, enzeon, quimar, quimotrase, alpha-chymar, alpha-chymotrypsin A, alpha-chymotrypsin) is a digestive enzyme component of pancreatic juice acting in the duodenum, where it performs proteolysis, the breakdown of proteins and polypeptides.

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Coenzyme Q – cytochrome c reductase

The coenzyme Q: cytochrome c – oxidoreductase, sometimes called the cytochrome bc1 complex, and at other times complex III, is the third complex in the electron transport chain, playing a critical role in biochemical generation of ATP (oxidative phosphorylation).

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Copalyl diphosphate synthase

In enzymology, a copalyl diphosphate synthase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, geranylgeranyl diphosphate, and one product, (+)-copalyl diphosphate.

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CTP synthetase

CTP synthetase is an enzyme involved in pyrimidine biosynthesis that interconverts UTP and CTP.

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Cycloeucalenol cycloisomerase

In enzymology, a cycloeucalenol cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, cycloeucalenol, and one product, obtusifoliol.

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Cyclophilin

Cyclophilins are a family of proteins from vertebrates and other organisms that bind to ciclosporin (cyclosporin A), an immunosuppressant which is usually used to suppress rejection after internal organ transplants.

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CYP2D6

Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.

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CYP2E1

Cytochrome P450 2E1 (abbreviated CYP2E1) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body.

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CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.

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Cypridina-luciferin 2-monooxygenase

In enzymology, a Cypridina-luciferin 2-monooxygenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are Cypridina luciferin and O2, whereas its 3 products are oxidized Cypridina luciferin, CO2, and light.

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Cystathionine beta-lyase

Cystathionine beta-lyase, also commonly referred to as CBL or β-cystathionase, is an enzyme that primarily catalyzes the following α,β-elimination reaction Thus, the substrate of this enzyme is L-cystathionine, whereas its 3 products are homocysteine, pyruvate, and ammonia.

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Cystathionine gamma-lyase

Cystathionine gamma-lyase (CTH or CSE; also cystathionase) is an enzyme which breaks down cystathionine into cysteine, α-ketobutyrate, and ammonia.

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Cytochrome

Cytochromes are heme-containing proteins.

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Cytochrome c oxidase

The enzyme cytochrome c oxidase or Complex IV, is a large transmembrane protein complex found in bacteria, archaea, and in eukaryotes in their mitochondria.

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Cytochrome c peroxidase

Cytochrome c peroxidase, or CCP, is a water-soluble heme-containing enzyme of the peroxidase family that takes reducing equivalents from cytochrome ''c'' and reduces hydrogen peroxide to water: CCP can be derived from aerobically grown yeast strains and can be isolated in both native and recombinant forms with high yield from Saccharomyces cerevisae. The enzyme’s primary function is to eliminate toxic radical molecules produced by the cell which are harmful to biological systems.

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Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

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D-xylulose reductase

In enzymology, a D-xylulose reductase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are xylitol and NAD+, whereas its 3 products are D-xylulose, NADH, and H+.

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Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN.

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Deiodinase

Deiodinase (or iodide peroxidase or "Monodeiodinase") is a peroxidase enzyme that is involved in the activation or deactivation of thyroid hormones.

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Deoxyribonuclease

A deoxyribonuclease (DNase, for short) is an enzyme that catalyzes the hydrolytic cleavage of phosphodiester linkages in the DNA backbone, thus degrading DNA.

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Diacetyl reductase

Diacetyl reductase is the name of two acetoin forming enzymes.

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Dichloromethane dehalogenase

Dichloromethane dehalogenase is a lyase enzyme that generates formaldehyde.

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Dichloromuconate cycloisomerase

In enzymology, a dichloromuconate cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate, and one product, 2,4-dichloro-cis,cis-muconate.

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Dihydrobenzophenanthridine oxidase

Dihydrobenzophenanthridine oxidase (DHBP oxidase) is an enzyme.

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Dihydrofolate reductase

Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.

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Disulfide

In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.

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DMSO reductase

DMSO reductase is a molybdenum-containing enzyme that catalyzes reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS).

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DNA ligase

DNA ligase is a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.

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DNA methyltransferase

In biochemistry, the DNA methyltransferase (DNA MTase) family of enzymes catalyze the transfer of a methyl group to DNA.

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DnaB helicase

DnaB helicase is an enzyme in bacteria which opens the replication fork during DNA replication.

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Elastase

In molecular biology, elastase is an enzyme from the class of proteases (peptidases) that break down proteins.

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Endonuclease

Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain.

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Enoyl CoA isomerase

Enoyl-CoA-(∆) isomerase, also known as dodecenoyl-CoA-(∆) isomerase, 3,2-trans-enoyl-CoA isomerase, ∆3(cis),∆2(trans)-enoyl-CoA isomerase, or acetylene-allene isomerase, is an enzyme that catalyzes the conversion of cis-or trans-double bonds of fatty acids at gamma-carbon (position 3) to trans double bonds at beta-carbon (position 2).

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Ent-Copalyl diphosphate synthase

In enzymology, an ent-copalyl diphosphate synthase is an enzyme that catalyzes the chemical reaction: Hence, this enzyme has one substrate, geranylgeranyl pyrophosphate, and one product, ''ent''-copalyl pyrophosphate.

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Ester

In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.

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Ether

Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups.

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Exonuclease

Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain.

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Factor IX

Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1.

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Factor VII

Factor VII (blood-coagulation factor VIIa, activated blood coagulation factor VII, formerly known as proconvertin) is one of the proteins that causes blood to clot in the coagulation cascade.

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Factor X

Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade.

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Factor XI

Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade.

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Factor XII

Coagulation factor XII, also known as Hageman factor, is a plasma protein.

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Factor XIII

Factor XIII or fibrin stabilizing factor is an enzyme of the blood coagulation system that crosslinks fibrin.

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Farnesol 2-isomerase

In enzymology, a farnesol 2-isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 2-trans,6-trans-farnesol, and one product, 2-cis,6-trans-farnesol.

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FARSB

Phenylalanyl-tRNA synthetase beta chain is an enzyme that in humans is encoded by the FARSB gene.

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Firefly luciferase

Firefly luciferase is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles.

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FKBP

FKBP, or FK506 binding protein, is a family of proteins that have prolyl isomerase activity and are related to the cyclophilins in function, though not in amino acid sequence.

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FKBP10

FK506-binding protein 10 is a protein that in humans is encoded by the FKBP10 gene.

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FKBP1A

Peptidyl-prolyl cis-trans isomerase FKBP1A is an enzyme that in humans is encoded by the FKBP1A gene.

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FKBP1B

Peptidyl-prolyl cis-trans isomerase FKBP1B is an enzyme that in humans is encoded by the FKBP1B gene.

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FKBP2

FK506-binding protein 2 is a protein that in humans is encoded by the FKBP2 gene.

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FKBP3

FK506-binding protein 3 is a protein that in humans is encoded by the FKBP3 gene.

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FKBP5

FK506 binding protein 5, also known as FKBP5, is a protein which in humans is encoded by the FKBP5 gene.

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FKBP52

FK506-binding protein 4 is a protein that in humans is encoded by the FKBP4 gene.

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FKBP6

FK506 binding protein 6, also known as FKBP6, is a human gene.

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FKBP8

FK506-binding protein 8 is a protein that in humans is encoded by the FKBP8 gene.

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FKBP9

FK506-binding protein 9 is a protein that in humans is encoded by the FKBP9 gene.

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FKBPL

FK506-binding protein like, also known as FKBPL, is a protein that in humans is encoded by the FKBPL gene.

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Flavin group

Flavin (from Latin flavus, "yellow") is the common name for a group of organic compounds based on pteridine, formed by the tricyclic heterocycle isoalloxazine.

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Flavin prenyltransferase

Flavin prenyltransferase UbiX, that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD.

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Fructose 1,6-bisphosphatase

Fructose bisphosphatase is an enzyme that converts fructose-1,6-bisphosphate to fructose 6-phosphate in gluconeogenesis and the Calvin cycle which are both anabolic pathways.

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Fructose-bisphosphate aldolase

Fructose-bisphosphate aldolase, often just aldolase, is an enzyme catalyzing a reversible reaction that splits the aldol, fructose 1,6-bisphosphate, into the triose phosphates dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P).

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Furylfuramide isomerase

In enzymology, a furylfuramide isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide, and one product, (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.

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Gamma-glutamyltransferase

Gamma-glutamyltransferase (also γ-glutamyltransferase, GGT, gamma-GT) is a transferase (a type of enzyme) that catalyzes the transfer of gamma-glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate).

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Glucose oxidase

The glucose oxidase enzyme (GOx) also known as notatin (EC number 1.1.3.4) is an oxido-reductase that catalyses the oxidation of glucose to hydrogen peroxide and D-glucono-δ-lactone.

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Glutamine synthetase

Glutamine synthetase (GS) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine: Glutamate + ATP + NH3 → Glutamine + ADP + phosphate Glutamine Synthetase uses ammonia produced by nitrate reduction, amino acid degradation, and photorespiration.

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Glutathione peroxidase

Glutathione peroxidase (GPx) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage.

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Glutathione reductase

Glutathione reductase (GR) also known as glutathione-disulfide reductase (GSR) is an enzyme that in humans is encoded by the GSR gene.

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Glutathione S-transferase

Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification.

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Glyceraldehyde 3-phosphate dehydrogenase

Glyceraldehyde 3-phosphate dehydrogenase (abbreviated as GAPDH or less commonly as G3PDH) is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules.

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Glycerol dehydrogenase

Glycerol dehydrogenase (also known as NAD+-linked glycerol dehydrogenase, glycerol: NAD+ 2-oxidoreductase, GDH, GlDH, GlyDH) is an enzyme in the oxidoreductase family that utilizes the NAD+ to catalyze the oxidation of glycerol to form glycerone (dihydroxyacetone).

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Glycerol-3-phosphate dehydrogenase (NAD+)

In enzymology, a glycerol-3-phosphate dehydrogenase (NAD+) is an enzyme that catalyzes the chemical reaction The two substrates of this enzyme are sn-glycerol 3-phosphate and NAD+, whereas its 3 products are glycerone phosphate, NADH, and H+.

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Glycosylase

Glycosylases (EC 3.2) are enzymes that hydrolyze glycosyl compounds.

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GTP cyclohydrolase I

GTP cyclohydrolase I (GTPCH) is a member of the GTP cyclohydrolase family of enzymes.

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Guanylate cyclase

Guanylate cyclase (also known as guanyl cyclase, guanylyl cyclase, or GC) is a lyase enzyme.

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Halide

A halide is a binary phase, of which one part is a halogen atom and the other part is an element or radical that is less electronegative (or more electropositive) than the halogen, to make a fluoride, chloride, bromide, iodide, astatide, or theoretically tennesside compound.

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Halimadienyl-diphosphate synthase

Halimadienyl-diphosphate synthase (Rv3377c, halimadienyl diphosphate synthase, tuberculosinol diphosphate synthase, halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing)) is an enzyme with systematic name halima-5,13-dien-15-yl-diphosphate lyase (decyclizing).

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Haloacetate dehalogenase

In enzymology, a haloacetate dehalogenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are haloacetate and H2O, whereas its two products are glycolate and halide.

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Halohydrin dehalogenase

A halohydrin dehalogenase is an enzyme involved in the bacterial degradation of vicinal halohydrins.

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Helicase

Helicases are a class of enzymes vital to all living organisms.

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Heme

Heme or haem is a coordination complex "consisting of an iron ion coordinated to a porphyrin acting as a tetradentate ligand, and to one or two axial ligands." The definition is loose, and many depictions omit the axial ligands.

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Hepoxilin-epoxide hydrolase

In enzymology, a hepoxilin-epoxide hydrolase is an enzyme that catalyzes the conversion of the epoxyalcohol metabolites arachidonic acid, hepoxilin A3 and hepoxilin B3 to their tri-hydroxyl products, trioxolin A3 and trioxilin B3, respectively.

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Histone methyltransferase

Histone methyltransferases (HMT) are histone-modifying enzymes (e.g., histone-lysine N-methyltransferases and histone-arginine N-methyltransferases), that catalyze the transfer of one, two, or three methyl groups to lysine and arginine residues of histone proteins.

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HMG-CoA reductase

HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, officially abbreviated HMGCR) is the rate-controlling enzyme (NADH-dependent,; NADPH-dependent) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids.

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Homoserine dehydrogenase

In enzymology, a homoserine dehydrogenase is an enzyme that catalyzes the chemical reaction The 2 substrates of this enzyme are L-homoserine and NAD+ (or NADP+), whereas its 3 products are L-aspartate 4-semialdehyde, NADH (or NADPH), and H+.

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Hyaluronidase

Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid (HA).

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Hydrolase

Hydrolase is a class of enzyme that is commonly used as biochemical catalysts that utilize water to break a chemical bond.

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Hypoxanthine-guanine phosphoribosyltransferase

Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene.

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Inositol-3-phosphate synthase

In enzymology, an inositol-3-phosphate synthase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, D-glucose 6-phosphate, and one product, 1D-myo-inositol 3-phosphate.

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International Union of Biochemistry and Molecular Biology

The International Union of Biochemistry and Molecular Biology (IUBMB) is an international non-governmental organisation concerned with biochemistry and molecular biology.

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Intramolecular force

An intramolecular force is any force that binds together the atoms making up a molecule or compound, not to be confused with intermolecular forces, which are the forces present between molecules.

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Iron–sulfur protein

Iron–sulfur proteins are proteins characterized by the presence of iron–sulfur clusters containing sulfide-linked di-, tri-, and tetrairon centers in variable oxidation states.

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Iron—cytochrome-c reductase

In enzymology, an iron—cytochrome-c reductase (created 1972 as, transferred 2014 to) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ferrocytochrome c and Fe3+, whereas its two products are ferricytochrome c and Fe2+.

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Isochorismatase

In enzymology, an isochorismatase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are isochorismate and H2O, whereas its two products are 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate.

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Isocitrate dehydrogenase

Isocitrate dehydrogenase (IDH) and is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2.

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Isomerase

Isomerases are a general class of enzymes that convert a molecule from one isomer to another.

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Ketone

In chemistry, a ketone (alkanone) is an organic compound with the structure RC(.

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Kynureninase

Kynureninase or L-Kynurenine hydrolase (KYNU) is a PLP dependent enzyme that catalyses the cleavage of kynurenine (Kyn) into anthranilic acid (Ant).

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L-gulonolactone oxidase

L-gulonolactone oxidase (EC) is an enzyme that produces vitamin C, but is non-functional in Haplorrhini (including humans), in some bats, and in guinea pigs.

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L-xylulose reductase

Dicarbonyl/L-xylulose reductase, also known as carbonyl reductase II, is an enzyme that in human is encoded by the DCXR gene located on chromosome 17.

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Laccase

Laccases are copper-containing oxidase enzymes found in many plants, fungi, and microorganisms.

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Lactase

Lactase is an enzyme produced by many organisms.

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Lactate dehydrogenase

Lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells (animals, plants, and prokaryotes).

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Leukotriene C4 synthase

Leukotriene C4 synthase is an enzyme that in humans is encoded by the LTC4S gene.

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Leukotriene-A4 hydrolase

Leukotriene A4 hydrolase, also known as LTA4H is a human gene.

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Ligase

In biochemistry, a ligase is an enzyme that can catalyze the joining of two large molecules by forming a new chemical bond, usually with accompanying hydrolysis of a small pendant chemical group on one of the larger molecules or the enzyme catalyzing the linking together of two compounds, e.g., enzymes that catalyze joining of C-O, C-S, C-N, etc.

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Limonene-1,2-epoxide hydrolase

In enzymology, a limonene-1,2-epoxide hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are limonene-1,2-epoxide and H2O, whereas its product is limonene-1,2-diol.

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Linoleate isomerase

In enzymology, a linoleate isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 9-cis,12-cis-octadecadienoate, and one product, 9-cis,11-trans-octadecadienoate.

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Lipoprotein lipase

Lipoprotein lipase (LPL) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase.

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List of EC numbers (EC 1)

This list contains a list of EC numbers for the first group, EC 1, oxidoreductases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

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List of EC numbers (EC 2)

This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

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List of EC numbers (EC 3)

This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

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List of EC numbers (EC 4)

This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

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List of EC numbers (EC 5)

This list contains a list of EC numbers for the fifth group, EC 5, isomerases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

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List of EC numbers (EC 6)

This list contains a list of EC numbers for the sixth group, EC 6, ligases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

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Luciferase

Luciferase is a generic term for the class of oxidative enzymes that produce bioluminescence, and is usually distinguished from a photoprotein.

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Lyase

In biochemistry, a lyase is an enzyme that catalyzes the breaking (an "elimination" reaction) of various chemical bonds by means other than hydrolysis (a "substitution" reaction) and oxidation, often forming a new double bond or a new ring structure.

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Lycopene beta-cyclase

Lycopene beta-cyclase (CrtL, CrtL-b, CrtY) is an enzyme with systematic name carotenoid beta-end group lyase (decyclizing).

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Lycopene epsilon-cyclase

Lycopene epsilon-cyclase (CrtL-e, LCYe) is an enzyme with systematic name carotenoid psi-end group lyase (decyclizing).

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Lysozyme

Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase is an antimicrobial enzyme produced by animals that forms part of the innate immune system.

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Malate dehydrogenase

Malate dehydrogenase (MDH) is an enzyme that reversibly catalyzes the oxidation of malate to oxaloacetate using the reduction of NAD+ to NADH.

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Maleate isomerase

In enzymology, a maleate isomerase, or maleate cis-tran isomerase, is a member of the Asp/Glu racemase superfamily discovered in bacteria.

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Maleylacetoacetate isomerase

In enzymology, a maleylacetoacetate isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 4-maleylacetoacetate, and one product, 4-fumarylacetoacetate.

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Maleylpyruvate isomerase

In enzymology, a maleylpyruvate isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 3-maleylpyruvate, and one product, 3-fumarylpyruvate.

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Maltase

Maltase (alpha-glucosidase, glucoinvertase, glucosidosucrase, maltase-glucoamylase, alpha-glucopyranosidase, glucosidoinvertase, alpha-D-glucosidase, alpha-glucoside hydrolase, alpha-1,4-glucosidase, alpha-D-glucoside glucohydrolase) is an enzyme located in on the brush border of the small intestine that breaks down the disaccharide maltose.

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Mandelate racemase

Mandelate racemase is a bacterial enzyme which catalyzes the interconversion of the enantiomers of mandelate via an enol intermediate.

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Matrix metalloproteinase

Matrix metalloproteinases (MMPs), also known as matrixins, are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins.

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Metalloendopeptidase

A metalloendopeptidase is an enzyme that functions as a metalloproteinase endopeptidase.

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Methyl group

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.

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Methylenetetrahydrofolate reductase

Methylene tetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene.

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Methylmalonyl CoA epimerase

Methylmalonyl CoA epimerase (methylmalonyl-CoA racemase, methylmalonyl coenzyme A racemase, DL-methylmalonyl-CoA racemase, 2-methyl-3-oxopropanoyl-CoA 2-epimerase) is an enzyme involved in fatty acid catabolism that is encoded in human by the "MCEE" gene located on chromosome 2.

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Methyltransferase

Methyltransferases are a large group of enzymes that all methylate their substrates but can be split into several subclasses based on their structural features.

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Microsomal epoxide hydrolase

In enzymology, a microsomal epoxide hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are cis-stilbene oxide and H2O, whereas its product is (+)-(1R,2R)-1,2-diphenylethane-1,2-diol.

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Monoamine oxidase

L-Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines.

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Muconate lactonizing enzyme

Muconate lactonizing enzymes (muconate cycloisomerase I, cis,cis-muconate-lactonizing enzyme, cis,cis-muconate cycloisomerase, 4-carboxymethyl-4-hydroxyisocrotonolactone lyase (decyclizing), CatB, MCI, MLE, 2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)) are involved in the breakdown of lignin-derived aromatics, catechol and protocatechuate, to citric acid cycle intermediates as a part of the β-ketoadipate pathway in soil microbes.

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Mutase

A mutase is an enzyme of the isomerase class that catalyzes the shifting of a functional group from one position to another within the same molecule.

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Myeloperoxidase

Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene on chromosome 17.

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Na+/K+-ATPase

-ATPase (sodium-potassium adenosine triphosphatase, also known as the pump or sodium–potassium pump) is an enzyme (an electrogenic transmembrane ATPase) found in the plasma membrane of all animal cells.

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NADH dehydrogenase

NADH dehydrogenase (cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase, dihydrocodehydrogenase I dehydrogenase, dihydronicotinamide adenine dinucleotide dehydrogenase, diphosphopyridine diaphorase, DPNH diaphorase, NADH diaphorase, NADH hydrogenase, NADH oxidoreductase, NADH-menadione oxidoreductase, reduced diphosphopyridine nucleotide diaphorase) is an enzyme with systematic name NADH:acceptor oxidoreductase.

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Nicotinamide adenine dinucleotide

Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells.

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Nitrate reductase

Nitrate reductases are molybdoenzymes that reduce nitrate (NO) to nitrite (NO).

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Nitric oxide dioxygenase

Nitric oxide dioxygenase is an enzyme that catalyzes the conversion of nitric oxide (NO) to nitrate (NO).

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Nitric oxide synthase

Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine.

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Nitrilase

Nitrilase enzymes (nitrile aminohydrolase) catalyse the hydrolysis of nitriles to carboxylic acids and ammonia, without the formation of "free" amide intermediates.

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Nitrite reductase

Nitrite reductase refers to any of several classes of enzymes that catalyze the reduction of nitrite.

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Nitrogen

Nitrogen is a chemical element with symbol N and atomic number 7.

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Nitrogenase

Nitrogenases are enzymes that are produced by certain bacteria, such as cyanobacteria (blue-green algae).

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Nuclease

A nuclease (also archaically known as nucleodepolymerase or polynucleotidase) is an enzyme capable of cleaving the phosphodiester bonds between monomers of nucleic acids.

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Oplophorus-luciferin 2-monooxygenase

In enzymology, an Oplophorus-luciferin 2-monooxygenase is a luciferase, an enzyme, from the deep-sea shrimp Oplophorus gracilirostris that catalyzes the chemical reaction: Thus, the two substrates of this enzyme are the luciferin, Coelenterazine and O2, whereas its 3 products are the oxyluciferin, Coelenteramide, CO2, and light.

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Ornithine decarboxylase

The enzyme ornithine decarboxylase (ODC) catalyzes the decarboxylation of ornithine (a product of the urea cycle) to form putrescine.

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Ornithine transcarbamylase

Ornithine transcarbamylase (OTC) (also called ornithine carbamoyltransferase) is an enzyme that catalyzes the reaction between carbamoyl phosphate (CP) and ornithine (Orn) to form citrulline (Cit) and phosphate (Pi).

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Oxidoreductase

In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor.

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Oxoglutarate dehydrogenase complex

The oxoglutarate dehydrogenase complex (OGDC) or α-ketoglutarate dehydrogenase complex is an enzyme complex, most commonly known for its role in the citric acid cycle.

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Oxygen

Oxygen is a chemical element with symbol O and atomic number 8.

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Parvulin

Parvulin, a 92-amino acid protein discovered in E. coli in 1994,Rahfeld JU, Schierhorn A, Mann KH.

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Pepsin

Pepsin is an endopeptidase that breaks down proteins into smaller peptides (that is, a protease).

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Peptide bond

A peptide bond is a covalent chemical bond linking two consecutive amino acid monomers along a peptide or protein chain.

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Peroxidase

Peroxidases (EC number) are a large family of enzymes that typically catalyze a reaction of the form: For many of these enzymes the optimal substrate is hydrogen peroxide, but others are more active with organic hydroperoxides such as lipid peroxides.

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Peroxide

Peroxide is a compound with the structure R-O-O-R. The O−O group in a peroxide is called the peroxide group or peroxo group.

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Phenylalanine ammonia-lyase

Phenylalanine ammonia lyase is an enzyme that catalyzes a reaction converting L-phenylalanine to ammonia and ''trans''-cinnamic acid.

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Phenylalanine hydroxylase

Phenylalanine hydroxylase (PAH) is an enzyme that catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine.

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Phenylalanine racemase (ATP-hydrolysing)

The enzyme phenylalanine racemase (phenylalanine racemase, phenylalanine racemase (adenosine triphosphate-hydrolysing), gramicidin S synthetase I) is the enzyme that acts on amino acids and derivatives.

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Phosphatase

A phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol.

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Phosphoglucomutase

Phosphoglucomutase is an enzyme that transfers a phosphate group on an α-D-glucose monomer from the 1' to the 6' position in the forward direction or the 6' to the 1' position in the reverse direction.

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Phospholipase

A phospholipase is an enzyme that hydrolyzes phospholipids into fatty acids and other lipophilic substances.

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Photoisomerase

A photoisomerase is a protein in the eye that is responsible for isomerizing photopigments.

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Plasmepsin

Plasmepsins are a class of at least 10 enzymes (and) produced by the Plasmodium falciparum parasite.

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Plasmin

Plasmin is an important enzyme present in blood that degrades many blood plasma proteins, including fibrin clots.

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Prolycopene isomerase

Prolycopene isomerase (CRTISO, carotene cis-trans isomerase, ZEBRA2 (gene), carotene isomerase, carotenoid isomerase) is an enzyme with systematic name 7,9,7',9'-tetracis-lycopene cis-trans-isomerase.

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Prolyl endopeptidase

Prolyl endopeptidase (PE) also known as prolyl oligopeptidase or post-proline cleaving enzyme is an enzyme that in humans is encoded by the PREP gene.

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Prolyl isomerase

Prolyl isomerase (also known as peptidylprolyl isomerase or PPIase) is an enzyme found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline.

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Propanediol-phosphate dehydrogenase

In enzymology, a propanediol-phosphate dehydrogenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are propane-1,2-diol 1-phosphate and NAD+, whereas its 3 products are hydroxyacetone phosphate, NADH, and H+.

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Prosolanapyrone-III cycloisomerase

Prosolanapyrone-III cycloisomerase (Sol5, SPS, solanapyrone synthase (bifunctional enzyme: prosolanapyrone II oxidase/prosolanapyrone III cyclosiomerase)) is an enzyme with systematic name prosolanapyrone-III:(-)-solanapyrone A isomerase.

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Protease

A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.

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Protein C

Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, is a zymogen, the activated form of which plays an important role in regulating anticoagulation, inflammation, cell death, and maintaining the permeability of blood vessel walls in humans and other animals.

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Protein disulfide-isomerase

Protein disulfide isomerase, or PDI, is an enzyme in the endoplasmic reticulum (ER) in eukaryotes and the periplasm of bacteria that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold.

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Proteinase K

In molecular biology Proteinase K (protease K, endopeptidase K, Tritirachium alkaline proteinase, Tritirachium album serine proteinase, Tritirachium album proteinase K) is a broad-spectrum serine protease.

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Protoporphyrinogen oxidase

Protoporphyrinogen oxidase is an enzyme that in humans is encoded by the PPOX gene.

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Pyruvate carboxylase

Pyruvate carboxylase (PC) encoded by the gene PC is an enzyme of the ligase class that catalyzes (depending on the species) the physiologically irreversible carboxylation of pyruvate to form oxaloacetate (OAA).

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Pyruvate dehydrogenase

Pyruvate dehydrogenase is the first component enzyme of pyruvate dehydrogenase complex (PDC).

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Quinone

The quinones are a class of organic compounds that are formally "derived from aromatic compounds by conversion of an even number of –CH.

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RecQ helicase

RecQ helicase is a family of helicase enzymes initially found in Escherichia coli that has been shown to be important in genome maintenance.

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Renilla-luciferin 2-monooxygenase

Renilla-luciferin 2-monooxygenase, Renilla luciferase, or RLuc, is a bioluminescent enzyme found in Renilla reniformis, belonging to a group of coelenterazine luciferases.

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Renin

Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that mediates the volume of extracellular fluid (blood plasma, lymph and interstitial fluid), and arterial vasoconstriction.

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Rennet

Rennet is a complex set of enzymes produced in the stomachs of ruminant mammals.

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Restriction enzyme

A restriction enzyme or restriction endonuclease is an enzyme that cleaves DNA into fragments at or near specific recognition sites within the molecule known as restriction sites.

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Retinal isomerase

In enzymology, a retinal isomerase is an enzyme that catalyzes the isomerisation of trans Retinal in eye into 11-cis-retinal which is form suitable to bind with protein opsin.

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Retinol isomerase

In enzymology, a retinol isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, all-trans-retinol, and one product, 11-cis-retinol.

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Ribonuclease

Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components.

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Ribonuclease H

Ribonuclease H (abbreviated RNase H or RNH) is a family of non-sequence-specific endonuclease enzymes that catalyze the cleavage of RNA in an RNA/DNA substrate via a hydrolytic mechanism.

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RuBisCO

Ribulose-1,5-bisphosphate carboxylase/oxygenase, commonly known by the abbreviations RuBisCO, RuBPCase, or RuBPco, is an enzyme involved in the first major step of carbon fixation, a process by which atmospheric carbon dioxide is converted by plants and other photosynthetic organisms to energy-rich molecules such as glucose.

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S-adenosyl-L-homocysteine hydrolase

S-adenosyl-L-homocysteine hydrolase (AdoHcyase) is an enzyme of the activated methyl cycle, responsible for the reversible hydration of S-adenosyl-L-homocysteine into adenosine and homocysteine.

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Sarcosine oxidase

Sarcosine oxidase is an enzyme that catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, 5,10-CH2-tetrahydrofolate in a reaction requiring H4-tetrahydrofolate and oxygen.

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Separase

Separase, also known as separin, is a cysteine protease responsible for triggering anaphase by hydrolysing cohesin, which is the protein responsible for binding sister chromatids during the early stage of anaphase.

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Serine protease

Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins, in which serine serves as the nucleophilic amino acid at the (enzyme's) active site.

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Serine racemase

Serine racemase is an enzyme which generates D-serine from L-serine.

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Steroid Delta-isomerase

In enzymology, a steroid Δ5-isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, a 3-oxo-Δ5-steroid, and one product, a 3-oxo-Δ4-steroid.

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Sucrase

Sucrase is a digestive enzyme secreted in the small intestine.

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Sulfite oxidase

Sulfite oxidase is an enzyme in the mitochondria of all eukaryotes.

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Superoxide dismutase

Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2&minus) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2).

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Syn-copalyl-diphosphate synthase

Syn-copalyl-diphosphate synthase (OsCyc1, OsCPSsyn, syn-CPP synthase, syn-copalyl diphosphate synthase) is an enzyme with systematic name 9alpha-copalyl-diphosphate lyase (decyclizing).

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Terpentedienyl-diphosphate synthase

Terpentedienyl-diphosphate synthase (terpentedienol diphosphate synthase, Cyc1, clerodadienyl diphosphate synthase) is an enzyme with systematic name terpentedienyl-diphosphate lyase (decyclizing).

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Tetrahydroxypteridine cycloisomerase

In enzymology, a tetrahydroxypteridine cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, tetrahydroxypteridine, and one product, xanthine-8-carboxylate.

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Thiaminase

Thiaminase is an enzyme that metabolizes or breaks down thiamine into two molecular parts.

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Thiamine oxidase

In enzymology, a thiamine oxidase is an enzyme that catalyzes the chemical reaction The 3 substrates of this enzyme are thiamine, O2, and H2O, whereas its two products are thiamine acetic acid and H2O2.

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Thioredoxin reductase

Thioredoxin reductases (TR, TrxR) are the only known enzymes to reduce thioredoxin (Trx).

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Thrombin

Thrombin (fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene.

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Thyroid peroxidase

Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid.

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Tissue plasminogen activator

Tissue plasminogen activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots.

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Topoisomerase

Topoisomerases are enzymes that participate in the overwinding or underwinding of DNA.

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Trans-epoxysuccinate hydrolase

In enzymology, a trans-epoxysuccinate hydrolase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are trans-2,3-epoxysuccinate and H2O, whereas its product is meso-tartrate.

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Transferase

A transferase is any one of a class of enzymes that enact the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor).

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Transglutaminase

A transglutaminase is an enzyme that catalyzes the formation of an isopeptide bond between a free amine group (e.g., protein- or peptide-bound lysine) and the acyl group at the end of the side chain of protein- or peptide-bound glutamine.

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Trypsin

Trypsin is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyzes proteins.

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Trypsinogen

Trypsinogen (EC 3.4.23.18/20/21/23/24/26) is the precursor form or zymogen of trypsin, a digestive enzyme.

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Tryptophan synthase

Tryptophan synthase or tryptophan synthetase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan.

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Tyrosinase

Tyrosinase is an oxidase that is the rate-limiting enzyme for controlling the production of melanin.

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Ubiquitin carboxy-terminal hydrolase L1

Ubiquitin carboxy-terminal hydrolase L1 (ubiquitin C-terminal hydrolase, UCH-L1) is a deubiquitinating enzyme.

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UDP-glucose 4-epimerase

The enzyme UDP-glucose 4-epimerase, also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells.

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Urate oxidase

The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate.

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Urease

Ureases, functionally, belong to the superfamily of amidohydrolases and phosphotriesterases.

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Uridine monophosphate synthetase

Uridine monophosphate synthase (UMPS) (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) is the enzyme that catalyses the formation of uridine monophosphate (UMP), an energy-carrying molecule in many important biosynthetic pathways.

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Watasenia-luciferin 2-monooxygenase

In enzymology, a Watasenia-luciferin 2-monooxygenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are Watasenia luciferin and O2, whereas its 3 products are oxidized Watasenia luciferin, CO2, and hn.

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Xanthine oxidase

Xanthine oxidase (XO, sometimes XAO) is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species.

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Zeta-carotene isomerase

Zeta-carotene isomerase (Z-ISO, 15-cis-zeta-carotene isomerase) is an enzyme with systematic name 9,15,9'-tricis-zeta-carotene cis-trans-isomerase.

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(R,R)-butanediol dehydrogenase

In enzymology, a (R,R)-butanediol dehydrogenase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are (R,R)-butane-2,3-diol and NAD+, whereas its 3 products are (R)-acetoin, NADH, and H+.

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(S)-beta-macrocarpene synthase

(S)-beta-macrocarpene synthase (TPS6, TPS11) is an enzyme with systematic name (S)-beta-macrocarpene lyase (decyclizing).

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2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase

In enzymology, a 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide, and one product, trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.

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3-carboxy-cis,cis-muconate cycloisomerase

In enzymology, a 3-carboxy-cis,cis-muconate cycloisomerase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate, and one product, cis,cis-butadiene-1,2,4-tricarboxylate.

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4-Hydroxyphenylpyruvate dioxygenase

4-Hydroxyphenylpyruvate dioxygenase (HPPD), also known as α-ketoisocaproate dioxygenase (KIC dioxygenase), is an Fe(II)-containing non-heme oxygenase that catalyzes the second reaction in the catabolism of tyrosine - the conversion of 4-hydroxyphenylpyruvate into homogentisate.

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6-carboxytetrahydropterin synthase

6-carboxytetrahydropterin synthase (CPH4 synthase, queD (gene), ToyB, ykvK (gene)) is an enzyme with systematic name 7,8-dihydroneopterin 3'-triphosphate acetaldehyde-lyase (6-carboxy-5,6,7,8-tetrahydropterin and triphosphate-forming).

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List of EC numbers, List of enzyme.

References

[1] https://en.wikipedia.org/wiki/List_of_enzymes

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