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List of withdrawn drugs

Index List of withdrawn drugs

Drugs or medicines may be withdrawn from commercial markets because of risks to patients, but also because of commercial reasons (e.g. lack of demand and relatively high production costs). [1]

192 relations: Abbott Laboratories, Adderall, Adverse drug reaction, Adverse effect, Agranulocytosis, Alatrofloxacin, Alclofenac, Alfadolone, Alfaxalone, Alfaxolone/alfadolone, Alosetron, Alpidem, Amineptine, Aminophenazone, Amobarbital, Anagestone acetate, Anaphylaxis, Annals of Emergency Medicine, Annals of Internal Medicine, Antrafenine, Aprotinin, Ardeparin sodium, Astemizole, Bendazac, Benoxaprofen, Benziodarone, Bezitramide, Bithionol, Bromfenac, Bronchospasm, Bucetin, Buformin, Butamben, Canrenone, Cardiotoxicity, Catechin, Cerivastatin, Chlormadinone, Chlormezanone, Chlorphentermine, Cinepazide, Cisapride, Clinical trial, Clioquinol, Clobutinol, Cloforex, Cyclobarbital, Cyclofenil, Dantron, Dermatology, ..., Dexatrim, Dexfenfluramine, Dextropropoxyphene, Dietary supplement, Diethylstilbestrol, Difemerine, Dihydrostreptomycin, Dimazole, Dithiazanine iodide, Dofetilide, Drotrecogin alfa, Drug overdose, Ebrotidine, Efalizumab, Electroconvulsive therapy, Encainide, Ethyl carbamate, Etretinate, European Medicines Agency, Fenclofenac, Fenclozic acid, Fenfluramine, Fenfluramine/phentermine, Fenoterol, Feprazone, Fipexide, Flosequinan, Flunitrazepam, Food and Drug Administration, Gatifloxacin, Gemtuzumab ozogamicin, Glafenine, Grepafloxacin, Guillain–Barré syndrome, Heart arrhythmia, Hemolytic anemia, Hepatotoxicity, Hydromorphone, Indalpine, Indoprofen, Iproniazid, Isoxicam, Kava, Ketorolac, Labetalol, Lactic acidosis, Leprosy, Levacetylmethadol, Levamisole, Liver failure, Lumiracoxib, Lysergic acid diethylamide, Mebanazine, Medication, Merck & Co., Metamizole, Metandienone, Methapyrilene, Methaqualone, Methylhexanamine, Metipranolol, Metofoline, Mibefradil, Minaprine, Moxisylyte, Multiple myeloma, Mutagen, Muzolimine, Myocardial infarction, Natalizumab, Nefazodone, Nialamide, Nikethamide, Nomifensine, Orphan drug, Oxeladin, Oxyphenbutazone, Oxyphenisatine, Pemoline, Pentobarbital, Pentylenetetrazol, Pergolide, Phenacetin, Phenformin, Phenolphthalein, Phenoxypropazine, Phentermine, Phenylbutazone, Phenylpropanolamine, Pirprofen, Postmarketing surveillance, Prenylamine, Press release, Proglumide, Progressive multifocal leukoencephalopathy, Pronethalol, Propanidid, Prostaglandin E2, Proxibarbital, Pyrovalerone, Rapacuronium bromide, Remoxipride, Rhabdomyolysis, Rimonabant, Rofecoxib, Rosiglitazone, Secobarbital, Sertindole, Sibutramine, Sitaxentan, Sorivudine, Sparfloxacin, Stevens–Johnson syndrome, Substance abuse, Substance dependence, Sulfamethoxypyridazine, Sulfametoxydiazine, Suprofen, Tegaserod, Temafloxacin, Temazepam, Teratology, Terfenadine, Terodiline, Tetrazepam, Thalidomide, Thenalidine, Thiobutabarbital, Thioridazine, Tienilic acid, Tolcapone, Tolrestat, Triazolam, Triparanol, Troglitazone, Trovafloxacin, Tryptophan, Valdecoxib, Vincamine, Ximelagatran, Zimelidine, Zomepirac. Expand index (142 more) »

Abbott Laboratories

Abbott Laboratories is an American health care company with headquarters in Lake Bluff, Illinois, United States.

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Adderall

Adderall, Adderall XR, and Mydayis are combination drugs containing four salts of the two enantiomers of amphetamine, a central nervous system (CNS) stimulant of the phenethylamine class.

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Adverse drug reaction

An adverse drug reaction (ADR) is an injury caused by taking a medication.

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Adverse effect

In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery.

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Agranulocytosis

Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous leukopenia (lowered white blood cell count), most commonly of neutrophils causing a neutropenia in the circulating blood.

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Alatrofloxacin

Alatrofloxacin (Trovan IV) is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt.

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Alclofenac

Alclofenac is a nonsteroidal anti-inflammatory drug (NSAID).

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Alfadolone

Alfadolone (INN), or alphadolone is a neuroactive steroid and general anesthetic.

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Alfaxalone

Alfaxalone, also known as alphaxalone or alphaxolone and sold under the brand name Alfaxan, is a neuroactive steroid and general anesthetic which is used in veterinary practice as an induction agent for anesthesia and as an injectable anesthetic.

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Alfaxolone/alfadolone

Alfaxolone/alfadolone (brand names Althesin (human), Saffan (veterinary) is a short acting intravenous anaesthetic agent. It was withdrawn from the market due to severe drug reactions. It is composed of a 3:1 mixture of alfaxalone and alfadolone, two neurosteroids.

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Alosetron

Alosetron (original brand name: Lotronex; originator: GSK) is a 5-HT3 antagonist used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.

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Alpidem

Alpidem (Ananxyl) is an anxiolytic drug from the imidazopyridine family, related to the more well known sleeping medication zolpidem.

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Amineptine

Amineptine, sold under the brand name Survector among others, is an atypical antidepressant of the tricyclic antidepressant (TCA) family.

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Aminophenazone

Aminophenazone (or aminopyrine, amidopyrine, Piramidon) is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties but has risk of agranulocytosis.

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Amobarbital

Amobarbital (formerly known as amylobarbitone or sodium amytal) is a drug that is a barbiturate derivative.

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Anagestone acetate

Anagestone acetate, sold under the brand names Anatropin and Neo-Novum, is a progestin medication which was withdrawn from medical use.

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Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

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Annals of Emergency Medicine

The Annals of Emergency Medicine is a monthly peer-reviewed medical journal covering all aspects of emergency medicine care.

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Annals of Internal Medicine

Annals of Internal Medicine is an academic medical journal published by the American College of Physicians (ACP).

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Antrafenine

Antrafenine (Stakane) is a phenylpiperazine derivative drug invented in 1979.

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Aprotinin

The drug aprotinin (Trasylol, previously Bayer and now Nordic Group pharmaceuticals), is a small protein bovine pancreatic trypsin inhibitor (BPTI), or basic trypsin inhibitor of bovine pancreas, which is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes.

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Ardeparin sodium

No description.

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Astemizole

Astemizole (marketed under the brand name Hismanal, developmental code R43512) was a second-generation antihistamine drug that has a long duration of action.

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Bendazac

Bendazac (or bendazolic acid) is a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.

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Benoxaprofen

Benoxaprofen, also known as Benoxaphen, is a chemical compound with the formula C16H12ClNO3.

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Benziodarone

Benziodarone is a vasodilator.

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Bezitramide

Bezitramide is an opioid analgesic.

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Bithionol

Bithionol is an anthelmintic used to treat Anoplocephala perfoliata (tapeworms) in horses and Fasciola hepatica (liver flukes).

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Bromfenac

Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) marketed in the US as an ophthalmic solution (current brand names Prolensa and Bromday,Drugs.com: for bromfenac sodium. prior formulation brand name Xibrom, which has since been discontinued) by ISTA Pharmaceuticals for short-term, local use.

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Bronchospasm

Bronchospasm or a bronchial spasm is a sudden constriction of the muscles in the walls of the bronchioles.

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Bucetin

Bucetin (INN, BAN) is an analgesic and antipyretic that is no longer marketed.

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Buformin

Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class, chemically related to metformin and phenformin.

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Butamben

Butamben is a local anesthetic.

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Canrenone

Canrenone, sold under the brand names Contaren, Luvion, Phanurane, and Spiroletan, is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium.

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Cardiotoxicity

Cardiotoxicity is the occurrence of heart electrophysiology dysfunction or muscle damage.

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Catechin

Catechin is a flavan-3-ol, a type of natural phenol and antioxidant.

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Cerivastatin

Cerivastatin (INN, brand names: Baycol, Lipobay) is a synthetic member of the class of statins used to lower cholesterol and prevent cardiovascular disease.

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Chlormadinone

Chlormadinone is a progestin which was never marketed.

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Chlormezanone

Chlormezanone (marketed under the brandname Trancopal or Fenaprim) is a drug used as an anxiolytic and a muscle relaxant.

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Chlorphentermine

Chlorphentermine (trade names Apsedon, Desopimon, Lucofen) is a serotonergic appetite suppressant of the amphetamine family.

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Cinepazide

Cinepazide or cinepazide maleate (Kelinao or Anjieli in ChinaDrugs.com Page accessed Aug 3, 201520 Oct 2010) is a vasodilator used in China for the treatment of cardiovascular and cerebrovascular diseases, and peripheral vascular diseases.

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Cisapride

Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Clioquinol

Clioquinol (iodochlorhydroxyquin) is an antifungal drug and antiprotozoal drug.

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Clobutinol

Clobutinol is a cough suppressant distributed by Boehringer-Ingelheim, Novartis's Hexal (Sandoz), Stada and possibly other companies.

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Cloforex

Cloforex (Oberex) is an anorectic of the amphetamine class.

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Cyclobarbital

Cyclobarbital, also known as cyclobarbitol or cyclobarbitone, is a drug which is a barbiturate derivative.

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Cyclofenil

Cyclofenil (brand names Fertodur, Menopax, Ondonid, Ondogyne, Sexovid, others) is a selective estrogen receptor modulator (SERM) used as a gonadotropin stimulant which is or has been marketed in Europe, South Korea, Mexico, and Brazil, among other countries.

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Dantron

Dantron (INN), also known as chrysazin or 1,8-dihydroxyanthraquinone, is an organic substance, formally derived from anthraquinone by the replacement of two hydrogen atoms by hydroxyl groups (–OH).

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Dermatology

Dermatology (from ancient Greek δέρμα, derma which means skin and λογία, logia) is the branch of medicine dealing with the skin, nails, hair and its diseases.

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Dexatrim

Dexatrim is an over-the-counter (OTC) dietary supplement meant to assist with weight loss.

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Dexfenfluramine

Dexfenfluramine, marketed as dexfenfluramine hydrochloride under the name Redux, is a serotonergic anorectic drug: it reduces appetite by increasing the amount of extracellular serotonin in the brain.

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Dextropropoxyphene

Dextropropoxyphene is an analgesic in the opioid category, patented in 1955 and manufactured by Eli Lilly and Company.

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Dietary supplement

A dietary supplement is a manufactured product intended to supplement the diet when taken by mouth as a pill, capsule, tablet, or liquid.

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Diethylstilbestrol

Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is an estrogen medication which is mostly no longer used.

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Difemerine

Difemerine is an antimuscarinic.

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Dihydrostreptomycin

Dihydrostreptomycin is a derivative of streptomycin that has a bactericidal property.

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Dimazole

Dimazole (or diamthazole) is an antifungal.

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Dithiazanine iodide

Dithiazanine iodide is a chemical compound.

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Dofetilide

Dofetilide is a class III antiarrhythmic agent.

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Drotrecogin alfa

Drotrecogin alfa (activated) (Xigris, marketed by Eli Lilly and Company) is a recombinant form of human activated protein C that has anti-thrombotic, anti-inflammatory, and profibrinolytic properties.

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Drug overdose

The term drug overdose (or simply overdose or OD) describes the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced.

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Ebrotidine

Ebrotidine is an H2 receptor antagonist with gastroprotective activity against ethanol-, aspirin- or stress-induced gastric mucosal damage.

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Efalizumab

Efalizumab (trade name Raptiva, Genentech, Merck Serono) is a formerly available medication designed to treat autoimmune diseases, originally marketed to treat psoriasis.

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Electroconvulsive therapy

Electroconvulsive therapy (ECT), formerly known as electroshock therapy, and often referred to as shock treatment, is a psychiatric treatment in which seizures are electrically induced in patients to provide relief from mental disorders.

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Encainide

Encainide (trade name Enkaid) is a class Ic antiarrhythmic agent.

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Ethyl carbamate

Ethyl carbamate (also called urethane) is an organic compound with the formula CH3CH2OC(O)NH2.

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Etretinate

Etretinate (trade name Tegison) is a medication developed by Hoffmann–La Roche that was approved by the FDA in 1986 to treat severe psoriasis.

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European Medicines Agency

The European Medicines Agency (EMA) is a European Union agency for the evaluation of medicinal products.

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Fenclofenac

Fenclofenac is a nonsteroidal anti-inflammatory drug (NSAID) previously used in rheumatism.

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Fenclozic acid

Fenclozic acid is an analgesic, antipyretic, and anti-inflammatory drug.

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Fenfluramine

Fenfluramine, formerly sold under the brand name Pondimin among others, is an appetite suppressant which was used to treat obesity and is now no longer marketed.

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Fenfluramine/phentermine

The drug combination fenfluramine/phentermine, usually called fen-phen, was an anti-obesity treatment that utilized two anorectics.

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Fenoterol

Fenoterol is a β2 adrenoreceptor agonist designed to open up the airways to the lungs.

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Feprazone

Feprazone (or prenazone) is a drug used for joint and muscular pain.

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Fipexide

Fipexide (Attentil, Vigilor) is a psychoactive drug of the piperazine chemical class which was developed in Italy in 1983.

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Flosequinan

Flosequinan is a quinolone vasodilator that was discovered and developed by Boots UK and was sold for about a year under the trade name Manoplax.

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Flunitrazepam

Flunitrazepam, also known as Rohypnol among other names, is an intermediate acting benzodiazepine used in some countries to treat severe insomnia and in fewer, early in anesthesia.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Gatifloxacin

Gatifloxacin sold under the brand names Gatiflo, Tequin and Zymar, is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.

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Gemtuzumab ozogamicin

Gemtuzumab ozogamicin (marketed by Wyeth as Mylotarg) is a drug-linked monoclonal antibody (an antibody-drug conjugate) that was used to treat acute myeloid leukemia from 2000 to 2010.

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Glafenine

Glafenine is a nonsteroidal anti-inflammatory drug (NSAID).

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Grepafloxacin

Grepafloxacin hydrochloride (trade name Raxar, Glaxo Wellcome) was an oral broad-spectrum fluoroquinolone antibacterial agent used to treat bacterial infections.

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Guillain–Barré syndrome

Guillain–Barré syndrome (GBS) is a rapid-onset muscle weakness caused by the immune system damaging the peripheral nervous system.

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Heart arrhythmia

Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.

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Hemolytic anemia

Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular, but usually in the spleen).

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Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.

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Hydromorphone

Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid, among others, is a centrally acting pain medication of the opioid class.

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Indalpine

Indalpine (INN, BAN; brand name Upstène; developmental code name LM-5008) is a selective serotonin reuptake inhibitor (SSRI) class drug that was briefly marketed.

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Indoprofen

Indoprofen is a nonsteroidal anti-inflammatory drug (NSAID).

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Iproniazid

Iproniazid (Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class.

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Isoxicam

Isoxicam is a nonsteroidal anti-inflammatory drug (NSAID) that was taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions.

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Kava

Kava or kava kava or Piper methysticum (Latin "pepper" and Latinized Greek "intoxicating") is a crop of the Pacific Islands.

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Ketorolac

Ketorolac, sold under the brand name Toradol among others, is a nonsteroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives, used as an analgesic.

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Labetalol

Labetalol is a medication used to treat high blood pressure.

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Lactic acidosis

Lactic acidosis is a medical condition characterized by the buildup of lactate (especially L-lactate) in the body, which results in an excessively low pH in the bloodstream.

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Leprosy

Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacterium Mycobacterium leprae or Mycobacterium lepromatosis.

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Levacetylmethadol

Levacetylmethadol (INN), levomethadyl acetate (USAN), OrLAAM (trade name) or levo-α-acetylmethadol (LAAM) is a synthetic opioid similar in structure to methadone.

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Levamisole

Levamisole, sold under the trade name Ergamisol among others, is a medication used to treat parasitic worm infections.

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Liver failure

Liver failure or hepatic insufficiency is the inability of the liver to perform its normal synthetic and metabolic function as part of normal physiology.

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Lumiracoxib

Lumiracoxib (rINN) is a carboxylic acid COX-2 selective inhibitor nonsteroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige (sometimes misquoted as "Prestige" by the media).

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Lysergic acid diethylamide

Lysergic acid diethylamide (LSD), also known as acid, is a psychedelic drug known for its psychological effects, which may include altered awareness of one's surroundings, perceptions, and feelings as well as sensations and images that seem real though they are not.

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Mebanazine

Mebanazine (trade name Actomol) is a monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was previously used as an antidepressant in the 1960s, but has since been withdrawn due to hepatotoxicity.

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Medication

A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Merck & Co.

Merck & Company, Inc., d.b.a. Merck Sharp & Dohme (MSD) outside the United States and Canada, is an American pharmaceutical company and one of the largest pharmaceutical companies in the world.

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Metamizole

Metamizole or dipyrone, is a painkiller, spasm reliever and fever reliever.

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Metandienone

Metandienone, also known as methandienone or methandrostenolone and sold under the brand name Dianabol among others, is an androgen and anabolic steroid (AAS) medication which is mostly no longer used.

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Methapyrilene

Methapyrilene is an antihistamine and anticholinergic of the pyridine chemical class which was developed in the early 1950s.

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Methaqualone

Methaqualone, sold under the brand name Quaalude (pronounced) and sometimes stylized "Quāālude" in the United States and Mandrax in the United Kingdom and South Africa, is a sedative and hypnotic medication.

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Methylhexanamine

Methylhexanamine (trade names Forthane, Geranamine) or methylhexamine, commonly known as 1,3-dimethylamylamine (1,3-DMAA) or simply dimethylamylamine (DMAA), is an indirect sympathomimetic drug invented and developed by Eli Lilly and Company and marketed as an inhaled nasal decongestant from 1944 until it was voluntarily withdrawn from the market in 1983.

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Metipranolol

Metipranolol (OptiPranolol, Betanol, Disorat, Trimepranol) is a non-selective beta blocker used in eye drops to treat glaucoma.

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Metofoline

Metofoline (INN), also known as methofoline (USAN), is an opioid analgesic drug discovered in the 1950s by a team of Swiss researchers at Hoffmann-La Roche.

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Mibefradil

Mibefradil (Posicor) is a drug for the treatment of hypertension and chronic angina pectoris.

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Minaprine

Minaprine (INN, USAN, BAN) (brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.

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Moxisylyte

Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction.

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Multiple myeloma

Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.

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Mutagen

In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level.

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Muzolimine

Muzolimine is a High-ceiling loop diuretic.

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Myocardial infarction

Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.

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Natalizumab

Natalizumab is a humanized monoclonal antibody against the cell adhesion molecule α4-integrin.

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Nefazodone

Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant which was first marketed by Bristol-Myers Squibb in 1994 but has since largely been discontinued.

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Nialamide

Nialamide (Niamid, Niamide, Nuredal, Surgex) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant.

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Nikethamide

Nikethamide is a stimulant which mainly affects the respiratory cycle.

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Nomifensine

Nomifensine (Merital, Alival) is a norepinephrine-dopamine reuptake inhibitor, i.e. a drug that increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters.

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Orphan drug

An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.

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Oxeladin

Oxeladin is a cough suppressant.

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Oxyphenbutazone

Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID).

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Oxyphenisatine

Oxyphenisatine (or oxyphenisatin) is a laxative.

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Pemoline

Pemoline is a stimulant drug of the 4-oxazolidinone class.

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Pentobarbital

Pentobarbital (INN, AAN, BAN, USAN) or pentobarbitone (former AAN and BAN) is a short-acting barbiturate.

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Pentylenetetrazol

Pentylenetetrazol, also known as pentylenetetrazole, metrazol, pentetrazol (INN), pentamethylenetetrazol, Corazol, Cardiazol, deumacard or PTZ, is a drug formerly used as a circulatory and respiratory stimulant.

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Pergolide

Pergolide (trade names Permax, Prascend) is an ergoline-based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease (PD).

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Phenacetin

Phenacetin (or acetophenetidin) is a pain-relieving and fever-reducing drug, which was widely used between its introduction in 1887 and the 1983 ban imposed by the U.S. Food and Drug Administration.

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Phenformin

Phenformin is an antidiabetic drug from the biguanide class.

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Phenolphthalein

Phenolphthalein is a chemical compound with the formula C20H14O4 and is often written as "HIn" or "phph" in shorthand notation.

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Phenoxypropazine

Phenoxypropazine (trade name Drazine) is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine family.

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Phentermine

Phentermine (contracted from phenyl-tertiary-butylamine), also known as α,α-dimethylphenethylamine, is a psychostimulant drug of the substituted amphetamine chemical class, with pharmacology similar to amphetamine.

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Phenylbutazone

Phenylbutazone, often referred to as "bute," is a nonsteroidal anti-inflammatory drug (NSAID) for the short-term treatment of pain and fever in animals.

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Phenylpropanolamine

Phenylpropanolamine (PPA) is a sympathomimetic agent which is used as a decongestant and appetite suppressant.

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Pirprofen

Pirprofen was a nonsteroidal anti-inflammatory drug (NSAID) that was brought to market by Ciba-Geigy in 1982 as a treatment for arthritis and pain.

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Postmarketing surveillance

Postmarketing surveillance (PMS) (also post market surveillance) is the practice of monitoring the safety of a pharmaceutical drug or medical device after it has been released on the market and is an important part of the science of pharmacovigilance.

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Prenylamine

Prenylamine (Segontin) is a calcium channel blocker of the amphetamine chemical class which was used as a vasodilator in the treatment of angina pectoris; it was introduced in the 1960s by German manufacturer Albert-Roussel pharma gmbh which was acquired by Hoechst AG in 1974 and which in turn became part of Sanofi Aventis in 2005.

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Press release

A press release, news release, media release, press statement or video release is a written or recorded communication directed at members of the news media for the purpose of announcing something ostensibly newsworthy.

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Proglumide

Proglumide (Milid) is a drug that inhibits gastrointestinal motility and reduces gastric secretions.

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Progressive multifocal leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is a rare and usually fatal viral disease characterized by progressive damage (-pathy) or inflammation of the white matter (leuko-) of the brain (-encephalo-) at multiple locations (multifocal).

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Pronethalol

Pronethalol (Alderlin, Nethalide) was an early non-selective beta blocker clinical candidate.

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Propanidid

Propanidid is an ultra short-acting phenylacetate general anesthetic.

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Prostaglandin E2

Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin which is used as a medication.

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Proxibarbital

Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956.

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Pyrovalerone

Pyrovalerone (Centroton, 4-Methyl-β-keto-prolintane, Thymergix, O-2371) is a psychoactive drug with stimulant effects via acting as a norepinephrine-dopamine reuptake inhibitor (NDRI), and is used for the clinical treatment of chronic fatigue or lethargy and as an anorectic or appetite suppressant for weight loss purposes.

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Rapacuronium bromide

Rapacuronium bromide (brand name Raplon) is a rapidly acting, non-depolarizing aminosteroid neuromuscular blocker formerly used in modern anaesthesia, to aid and enable endotracheal intubation, which is often necessary to assist in the controlled ventilation of unconscious patients during surgery and sometimes in intensive care.

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Remoxipride

Remoxipride (Roxiam) is an atypical antipsychotic (although according to some sources it is a typical antipsychotic) which was previously used in Europe for the treatment of schizophrenia and acute mania but was withdrawn due to toxicity concerns (incidence of aplastic anemia in 1/10,000 patients).

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Rhabdomyolysis

Rhabdomyolysis is a condition in which damaged skeletal muscle breaks down rapidly.

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Rimonabant

Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) is an anorectic antiobesity drug that was first approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side effects; it was never approved in the United States.

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Rofecoxib

Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that has now been withdrawn over safety concerns.

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Rosiglitazone

Rosiglitazone (trade name Avandia) is an antidiabetic drug in the thiazolidinedione class.

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Secobarbital

Secobarbital sodium (marketed by Eli Lilly and Company, and subsequently by other companies as described below, under the brand name Seconal) is a barbiturate derivative drug that was patented in 1934 in the United States.

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Sertindole

Sertindole (brand names: Serdolect and Serlect) is an antipsychotic medication.

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Sibutramine

Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries.

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Sitaxentan

Sitaxentan sodium (TBC-11251) is a medication for the treatment of pulmonary arterial hypertension (PAH).

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Sorivudine

Sorivudine (INN), is a nucleoside analogue antiviral drug, marketed under trade names such as Usevir (Nippon Shoji, Eisai) and Brovavir (BMS).

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Sparfloxacin

Sparfloxacin (spar FLOX a sin), trade names Spacin in Bangladesh, Zagam and Zagam Respipac, is a fluoroquinolone antibiotic used in the treatment of bacterial infections.

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Stevens–Johnson syndrome

Stevens–Johnson syndrome (SJS) is a type of severe skin reaction.

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Substance abuse

Substance abuse, also known as drug abuse, is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others, and is a form of substance-related disorder.

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Substance dependence

Substance dependence also known as drug dependence is an adaptive state that develops from repeated drug administration, and which results in withdrawal upon cessation of drug use.

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Sulfamethoxypyridazine

Sulfamethoxypyridazine is a sulfonamide antibacterial.

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Sulfametoxydiazine

Sulfametoxydiazine (INN) or sulfamethoxydiazine (USAN: sulfameter) is a long-acting sulfonamide antibacterial.

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Suprofen

Suprofen is a nonsteroidal anti-inflammatory drug (NSAID) developed by Janssen Pharmaceutica that was marketed as 1% eye drops under the trade name Profenal.

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Tegaserod

Tegaserod is a 5-HT4 agonist manufactured by Novartis and sold under the names Zelnorm and Zelmac for the management of irritable bowel syndrome and constipation.

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Temafloxacin

Temafloxacin (marketed by Abbott Laboratories as Omniflox) is a fluoroquinolone antibiotic drug which was withdrawn from sale in the United States shortly after its approval in 1992 because of serious adverse effects resulting in three deaths.

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Temazepam

Temazepam (brand names Restoril and Normison, among others) is an intermediate-acting 3-hydroxy hypnotic of the benzodiazepine class of psychoactive drugs.

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Teratology

Teratology is the study of abnormalities of physiological development.

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Terfenadine

Terfenadine is an antihistamine formerly used for the treatment of allergic conditions.

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Terodiline

Terodiline is a drug used in urology as an antispasmodic.

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Tetrazepam

Tetrazepam (is marketed under the following brand names, Clinoxan, Epsipam, Myolastan, Musaril, Relaxam and Spasmorelax) is a benzodiazepine derivative with anticonvulsant, anxiolytic, muscle relaxant and slightly hypnotic properties.

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Thalidomide

Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs.

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Thenalidine

Thenalidine is an antihistamine with anticholinergic properties used as an antipruritic drug.

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Thiobutabarbital

Thiobutabarbital (Inactin, Brevinarcon) is a short-acting barbiturate derivative invented in the 1950s.

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Thioridazine

Thioridazine (Mellaril or Melleril) is a piperidine typical antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis.

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Tienilic acid

Tienilic acid (INN and BAN) or ticrynafen (USAN) is a loop diuretic drug with uric acid-lowering (uricosuric) action, formerly marketed for the treatment of hypertension.

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Tolcapone

Tolcapone (brand name Tasmar) is a drug used to treat Parkinson's disease (PD).

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Tolrestat

Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications.

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Triazolam

Triazolam (original brand name Halcion) is a central nervous system (CNS) depressant in the benzodiazepine class.

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Triparanol

Triparanol (INN, BAN) (brand and developmental code names MER/29, as well as many other brand names), patented in 1959 and introduced in the United States in 1960, was the first synthetic cholesterol-lowering drug.

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Troglitazone

Troglitazone (Rezulin, Resulin, Romozin, Noscal) is an antidiabetic and anti-inflammatory drug, and a member of the drug class of the thiazolidinediones.

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Trovafloxacin

Trovafloxacin (sold as Trovan by Pfizer and Turvel by Laboratorios Almirall) was a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.

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Tryptophan

Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins.

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Valdecoxib

Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms.

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Vincamine

Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), comprising about 25-65% of the indole alkaloids found in Vinca minor by weight.

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Ximelagatran

Ximelagatran (Exanta or Exarta, H 376/95) is an anticoagulant that has been investigated extensively as a replacement for warfarin that would overcome the problematic dietary, drug interaction, and monitoring issues associated with warfarin therapy.

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Zimelidine

Zimelidine (INN, BAN) (brand names Zimeldine, Normud, Zelmid) was one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants to be marketed.

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Zomepirac

Zomepirac is an orally effective nonsteroidal anti-inflammatory drug (NSAID) that has antipyretic actions.

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Redirects here:

List of medication withdrawn from the market, List of medications withdrawn for safety, Withdrawn drug.

References

[1] https://en.wikipedia.org/wiki/List_of_withdrawn_drugs

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