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19 relations: Antiprogestogen, Bayer, Binding selectivity, Breast cancer, Clinical trial, Dysmenorrhea, Endometriosis, International nonproprietary name, Mifepristone, Onapristone, Oral administration, Organic compound, Potency (pharmacology), Progesterone receptor, Receptor antagonist, Steroid, Ulipristal acetate, United States Adopted Name, Vilaprisan.
Antiprogestogen
Antiprogestogens, or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of drugs which prevent progestogens like progesterone from mediating their biological effects in the body.
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Bayer
Bayer AG is a German multinational, pharmaceutical and life sciences company.
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Binding selectivity
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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Clinical trial
Clinical trials are experiments or observations done in clinical research.
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Dysmenorrhea
Dysmenorrhea, also known as painful periods, or menstrual cramps, is pain during menstruation.
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Endometriosis
Endometriosis is a condition in which the endometrium, the layer of tissue that normally covers the inside of the uterus, grows outside of it.
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International nonproprietary name
The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.
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Mifepristone
Mifepristone, also known as RU-486, is a medication typically used in combination with misoprostol, to bring about an abortion.
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Onapristone
Onapristone (INN) (developmental code names ZK-89299, ZK-299) is a synthetic, steroidal antiprogestogen with additional antiglucocorticoid activity which was developed by Schering and described in 1984 but was never marketed.
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Oral administration
| name.
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Organic compound
In chemistry, an organic compound is generally any chemical compound that contains carbon.
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Potency (pharmacology)
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
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Progesterone receptor
The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
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Ulipristal acetate
Ulipristal acetate, sold under the brand name Ella among others, is a medication used for emergency birth control and uterine fibroids.
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United States Adopted Name
United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States.
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Vilaprisan
Vilaprisan (INN, USAN) (developmental code name BAY-1002670) is a synthetic, steroidal selective progesterone receptor modulator (SPRM) which is under development by Bayer HealthCare Pharmaceuticals for the treatment of endometriosis and uterine fibroids.
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Redirects here:
BAY 86-5044, BAY 865044, BAY-86-5044, BAY-865044, BAY86-5044, BAY865044, Lonaprisal, ZK 230,211, ZK 230211, ZK-230,211, ZK-230211, ZK-PRA, ZK230211.
