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32 relations: Antibiotic, Archaea, Autolysis (biology), Bacterial outer membrane, Bacteriophage, C-terminus, Cell wall, Cytokine release syndrome, Endopeptidase, Enzybiotics, Gram-negative bacteria, Gram-positive bacteria, Holin, Hydrolase, Lysozyme, Lytic cycle, Microbiota, Mucous membrane, N-Acetylglucosamine, N-Acetylmuramic acid, N-acetylmuramoyl-L-alanine amidase, N-terminus, OBPgp279, Peptidoglycan, Phage therapy, Protein Data Bank, Protein domain, Pseudopeptidoglycan, Signal peptide, Streptococcus pyogenes, Unified atomic mass unit, Virus.
Antibiotic
An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.
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Archaea
Archaea (or or) constitute a domain of single-celled microorganisms.
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Autolysis (biology)
In biology, autolysis, more commonly known as self-digestion, refers to the destruction of a cell through the action of its own enzymes.
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Bacterial outer membrane
The bacterial outer membrane is found in gram-negative bacteria.
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Bacteriophage
A bacteriophage, also known informally as a phage, is a virus that infects and replicates within Bacteria and Archaea.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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Cell wall
A cell wall is a structural layer surrounding some types of cells, just outside the cell membrane.
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Cytokine release syndrome
Cytokine release syndrome is a form of systemic inflammatory response syndrome that arises as a complication of some diseases or infections, and is also an adverse effect of some monoclonal antibody drugs, as well as adoptive T-cell therapies.
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Endopeptidase
Endopeptidase or endoproteinase are proteolytic peptidases that break peptide bonds of nonterminal amino acids (i.e. within the molecule), in contrast to exopeptidases, which break peptide bonds from end-pieces of terminal amino acids.
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Enzybiotics
Enzybiotics are an experimental antibiotic approach employing enzymes to combat pathogenic bacterial infections.
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Gram-negative bacteria
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the gram-staining method of bacterial differentiation.
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Gram-positive bacteria
Gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their cell wall.
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Holin
Holins are a diverse group of small proteins produced by dsDNA bacteriophages in order to trigger and control the degradation of the host's cell wall at the end of the lytic cycle.
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Hydrolase
Hydrolase is a class of enzyme that is commonly used as biochemical catalysts that utilize water to break a chemical bond.
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Lysozyme
Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase is an antimicrobial enzyme produced by animals that forms part of the innate immune system.
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Lytic cycle
The lytic cycle is one of the two cycles of viral reproduction (referring to bacterial viruses or bacteriophages), the other being the lysogenic cycle.
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Microbiota
A microbiota is an "ecological community of commensal, symbiotic and pathogenic microorganisms" found in and on all multicellular organisms studied to date from plants to animals.
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Mucous membrane
A mucous membrane or mucosa is a membrane that lines various cavities in the body and covers the surface of internal organs.
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N-Acetylglucosamine
N-Acetylglucosamine (N-acetyl-D-glucosamine, or GlcNAc, or NAG) is a monosaccharide and a derivative of glucose.
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N-Acetylmuramic acid
N-Acetylmuramic acid, or MurNAc, is the ether of lactic acid and ''N''-acetylglucosamine with a chemical formula of C11H19NO8.
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N-acetylmuramoyl-L-alanine amidase
In enzymology, a N-acetylmuramoyl-L-alanine amidase is an enzyme that catalyzes a chemical reaction that cleaves the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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OBPgp279
OBPgp279 is an endolysin that hydrolyzes peptidoglycan, a major constituent in bacterial membrane.
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Peptidoglycan
Peptidoglycan, also known as murein, is a polymer consisting of sugars and amino acids that forms a mesh-like layer outside the plasma membrane of most bacteria, forming the cell wall.
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Phage therapy
Phage therapy or viral phage therapy is the therapeutic use of bacteriophages to treat pathogenic bacterial infections.
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Protein Data Bank
The Protein Data Bank (PDB) is a crystallographic database for the three-dimensional structural data of large biological molecules, such as proteins and nucleic acids.
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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
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Pseudopeptidoglycan
Pseudopeptidoglycan (also known as pseudomureinWhite, David. (1995) The Physiology and Biochemistry of Prokaryotes, pages 6, 12-21. (Oxford: Oxford University Press)..) is a major cell wall component of some Archaea that differs from bacterial peptidoglycan in chemical structure, but resembles bacterial peptidoglycan in function and physical structure.
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Signal peptide
A signal peptide (sometimes referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a short peptide (usually 16-30 amino acids long) present at the N-terminus of the majority of newly synthesized proteins that are destined towards the secretory pathway.
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Streptococcus pyogenes
Streptococcus pyogenes is a species of Gram-positive bacteria.
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Unified atomic mass unit
The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).
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Virus
A virus is a small infectious agent that replicates only inside the living cells of other organisms.
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Endolysin, Endolysins, Lysins, Murein hydrolase, Murein hydrolases, Phage lysin.
References
[1] https://en.wikipedia.org/wiki/Lysin
