27 relations: Acyl group, Acyltransferase, Alkyl, Alkyl-lysophospholipids, Apoptosis, Blood plasma, Cell membrane, Edelfosine, Fatty acid, Hydrolysis, LPCAT1, Lysophospholipase, Lysophospholipid receptor, Macrophage, Microglia, Miltefosine, Multiple sclerosis, Myelin, Neoplasm, Perifosine, Phagocyte, Phagocytosis, Phosphatidylcholine, Phospholipase A2, Red blood cell, Vaccine, 1-Lysophosphatidylcholine.
Acyl group
An acyl group is a moiety derived by the removal of one or more hydroxyl groups from an oxoacid, including inorganic acids.
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Acyltransferase
Acyltransferase is a type of transferase enzyme that acts upon acyl groups.
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Alkyl
In organic chemistry, an alkyl substituent is an alkane missing one hydrogen.
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Alkyl-lysophospholipids
Alky-lysophospholipids (ALP) are synthetic analogues of lysophosphatidylcholines (LPC), also called lysolecithins.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Blood plasma
Blood plasma is a yellowish coloured liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Edelfosine
Edelfosine (ET-18-O-CH3; 1-octadecyl-2-O-methyl-glycero-3-phosphocholine) is a synthetic alkyl-lysophospholipid (ALP).
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Fatty acid
In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with a long aliphatic chain, which is either saturated or unsaturated.
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Hydrolysis
Hydrolysis is a term used for both an electro-chemical process and a biological one.
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LPCAT1
Lysophosphatidylcholine acyltransferase 1 is a protein in humans that is encoded by the LPCAT1 gene.
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Lysophospholipase
In enzymology, a lysophospholipase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are 2-lysophosphatidylcholine and H2O, whereas its two products are glycerophosphocholine and carboxylate.
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Lysophospholipid receptor
The lysophospholipid receptor (LPL-R) group are members of the G protein-coupled receptor family of integral membrane proteins that are important for lipid signaling.
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Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
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Microglia
Microglia are a type of neuroglia (glial cell) located throughout the brain and spinal cord.
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Miltefosine
Miltefosine, sold under the trade name Impavido among others, is a medication mainly used to treat leishmaniasis and free-living amoeba infections such as Naegleria fowleri.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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Myelin
Myelin is a lipid-rich substance that surrounds the axon of some nerve cells, forming an electrically insulating layer.
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Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
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Perifosine
Perifosine (also KRX-0401) is a drug candidate being developed for a variety of cancer indications.
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Phagocyte
Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells.
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Phagocytosis
In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.
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Phosphatidylcholine
Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup.
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Phospholipase A2
Phospholipases A2 (PLA2s) are enzymes that release fatty acids from the second carbon group of glycerol.
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Red blood cell
Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.
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Vaccine
A vaccine is a biological preparation that provides active acquired immunity to a particular disease.
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1-Lysophosphatidylcholine
2-acyl-sn-glycero-3-phosphocholines are a class of phospholipids that are intermediates in the metabolism of lipids.
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1-acylglycerol-3-phosphocholine, 2-lysolecithin, 2-lysophosphatidylcholine, 3-lysolecithin, Lysolecithin, Lysolecithins, Lysophospatidylcholine, Lysophosphatidyl choline, Lysophosphatidylcholines.
References
[1] https://en.wikipedia.org/wiki/Lysophosphatidylcholine