MK-886

MK-886, or L-663536, is a leukotriene antagonist. ^[1]

4 relations: Antileukotriene, Arachidonate 5-lipoxygenase, Atherosclerosis, 5-lipoxygenase-activating protein.

Antileukotriene

An antileukotriene, also known as leukotriene modifier and leukotriene receptor antagonist, is a medication which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist (cysteinyl leukotriene receptors) and consequently opposes the function of these inflammatory mediators; leukotrienes are produced by the immune system and serve to promote bronchoconstriction, inflammation, microvascular permeability, and mucus secretion in asthma and COPD.

See MK-886 and Antileukotriene

Arachidonate 5-lipoxygenase

Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme (EC 1.13.11.34) that in humans is encoded by the ALOX5 gene.

See MK-886 and Arachidonate 5-lipoxygenase

Atherosclerosis

Atherosclerosis is a pattern of the disease arteriosclerosis, characterized by development of abnormalities called lesions in walls of arteries.

See MK-886 and Atherosclerosis

5-lipoxygenase-activating protein

Arachidonate 5-lipoxygenase-activating protein also known as 5-lipoxygenase activating protein, or FLAP, is a protein that in humans is encoded by the ALOX5AP gene.

See MK-886 and 5-lipoxygenase-activating protein

References

[1] https://en.wikipedia.org/wiki/MK-886

Also known as L 663536, L-663,536, MK 886.

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