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Major histocompatibility complex, class II, DP alpha 1

Index Major histocompatibility complex, class II, DP alpha 1

Major histocompatibility complex, class II, DP alpha 1, also known as HLA-DPA1, is a human gene. [1]

13 relations: Antigen-presenting cell, Cytoplasm, Exon, Gene, HLA-DP, Human leukocyte antigen, Immune system, Major histocompatibility complex, MHC class II, Polymorphism (biology), Protein, Protein domain, Transmembrane protein.

Antigen-presenting cell

An antigen-presenting cell (APC) or accessory cell is a cell that displays antigen complexed with major histocompatibility complexes (MHCs) on their surfaces; this process is known as antigen presentation.

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Cytoplasm

In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.

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Exon

An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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HLA-DP

HLA-DP is a protein/peptide-antigen receptor and graft-versus-host disease antigen that is composed of 2 subunits, DPα and DPβ.

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Human leukocyte antigen

The human leukocyte antigen (HLA) system or complex is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Major histocompatibility complex

The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.

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MHC class II

MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells.

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Polymorphism (biology)

Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein domain

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.

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Transmembrane protein

A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.

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References

[1] https://en.wikipedia.org/wiki/Major_histocompatibility_complex,_class_II,_DP_alpha_1

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