72 relations: AARP, Acrolein, Acrylonitrile, Arsenic, ATM serine/threonine kinase, Base excision repair, Benign tumor, BRCA1, Breast, Breast cancer, Cadmium, Cancer, Cancer epigenetics, Carcinogen, Carcinogenesis, Chondrosarcoma, Chromosome, Colorectal cancer, DNA, DNA methylation, DNA methylation in cancer, DNA repair, Epstein–Barr virus, ERCC1, Exome, FANCB, Formaldehyde, Gene expression, Genetic hitchhiking, Genome instability, Genotoxicity, Head and neck cancer, Helicobacter pylori, Hepatitis B, Hepatitis C, Human papillomavirus infection, Human T-lymphotropic virus, International Agency for Research on Cancer, Kaposi's sarcoma-associated herpesvirus, Lesion, LIG4, Medical history, Melanoma, Merkel cell polyomavirus, MicroRNA, MLH1, NEIL1, Nevus, Nickel, Non-coding DNA, ..., Non-Hodgkin lymphoma, Non-small-cell lung carcinoma, Nucleotide excision repair, O-6-methylguanine-DNA methyltransferase, Osteosarcoma, Oxoguanine glycosylase, Pathology, Peripheral blood mononuclear cell, Promoter (genetics), Prostate cancer, Regulation of transcription in cancer, Risk assessment, RNA-induced silencing complex, Somatic (biology), Stomach cancer, Three prime untranslated region, Thyroid cancer, Transcription (biology), Transformation (genetics), Werner syndrome helicase, World Health Organization, XRCC1. Expand index (22 more) »
AARP
AARP (formerly American Association of Retired Persons) is a United States-based interest group whose stated mission is "empowering people to choose how they live as they age." According to the organization, as of 2018, it had more than 38 million members.
New!!: Malignant transformation and AARP · See more »
Acrolein
Acrolein (systematic name: propenal) is the simplest unsaturated aldehyde.
New!!: Malignant transformation and Acrolein · See more »
Acrylonitrile
Acrylonitrile is an organic compound with the formula CH2CHCN.
New!!: Malignant transformation and Acrylonitrile · See more »
Arsenic
Arsenic is a chemical element with symbol As and atomic number 33.
New!!: Malignant transformation and Arsenic · See more »
ATM serine/threonine kinase
ATM serine/threonine kinase, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks.
New!!: Malignant transformation and ATM serine/threonine kinase · See more »
Base excision repair
In biochemistry and genetics, base excision repair (BER) is a cellular mechanism that repairs damaged DNA throughout the cell cycle.
New!!: Malignant transformation and Base excision repair · See more »
Benign tumor
A benign tumor is a mass of cells (tumor) that lacks the ability to invade neighboring tissue or metastasize.
New!!: Malignant transformation and Benign tumor · See more »
BRCA1
BRCA1 and BRCA1 are a human gene and its protein product, respectively.
New!!: Malignant transformation and BRCA1 · See more »
Breast
The breast is one of two prominences located on the upper ventral region of the torso of primates.
New!!: Malignant transformation and Breast · See more »
Breast cancer
Breast cancer is cancer that develops from breast tissue.
New!!: Malignant transformation and Breast cancer · See more »
Cadmium
Cadmium is a chemical element with symbol Cd and atomic number 48.
New!!: Malignant transformation and Cadmium · See more »
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
New!!: Malignant transformation and Cancer · See more »
Cancer epigenetics
Cancer epigenetics is the study of epigenetic modifications to the DNA of cancer cells that do not involve a change in the nucleotide sequence.
New!!: Malignant transformation and Cancer epigenetics · See more »
Carcinogen
A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of cancer.
New!!: Malignant transformation and Carcinogen · See more »
Carcinogenesis
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.
New!!: Malignant transformation and Carcinogenesis · See more »
Chondrosarcoma
Chondrosarcoma is a cancer composed of cells derived from transformed cells that produce cartilage.
New!!: Malignant transformation and Chondrosarcoma · See more »
Chromosome
A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.
New!!: Malignant transformation and Chromosome · See more »
Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
New!!: Malignant transformation and Colorectal cancer · See more »
DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
New!!: Malignant transformation and DNA · See more »
DNA methylation
DNA methylation is a process by which methyl groups are added to the DNA molecule.
New!!: Malignant transformation and DNA methylation · See more »
DNA methylation in cancer
DNA methylation in cancer plays a variety of roles, helping to change the healthy regulation of gene expression to a disease pattern.
New!!: Malignant transformation and DNA methylation in cancer · See more »
DNA repair
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.
New!!: Malignant transformation and DNA repair · See more »
Epstein–Barr virus
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.
New!!: Malignant transformation and Epstein–Barr virus · See more »
ERCC1
DNA excision repair protein ERCC-1 is a protein that in humans is encoded by the ERCC1 gene.
New!!: Malignant transformation and ERCC1 · See more »
Exome
The exome is the part of the genome composed of exons, the sequences which, when transcribed, remain within the mature RNA after introns are removed by RNA splicing and contribute to the final protein product encoded by that gene.
New!!: Malignant transformation and Exome · See more »
FANCB
Fanconi anemia group B protein is a protein that in humans is encoded by the FANCB gene.
New!!: Malignant transformation and FANCB · See more »
Formaldehyde
No description.
New!!: Malignant transformation and Formaldehyde · See more »
Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
New!!: Malignant transformation and Gene expression · See more »
Genetic hitchhiking
Genetic hitchhiking, also called genetic draft or the hitchhiking effect, is when an allele changes frequency not because it itself is under natural selection, but because it is near another gene that is undergoing a selective sweep and that is on the same DNA chain.
New!!: Malignant transformation and Genetic hitchhiking · See more »
Genome instability
Genome instability (also genetic instability or genomic instability) refers to a high frequency of mutations within the genome of a cellular lineage.
New!!: Malignant transformation and Genome instability · See more »
Genotoxicity
In genetics, genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer.
New!!: Malignant transformation and Genotoxicity · See more »
Head and neck cancer
Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands.
New!!: Malignant transformation and Head and neck cancer · See more »
Helicobacter pylori
Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, microaerophilic bacterium usually found in the stomach.
New!!: Malignant transformation and Helicobacter pylori · See more »
Hepatitis B
Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver.
New!!: Malignant transformation and Hepatitis B · See more »
Hepatitis C
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver.
New!!: Malignant transformation and Hepatitis C · See more »
Human papillomavirus infection
Human papillomavirus infection is an infection by human papillomavirus (HPV).
New!!: Malignant transformation and Human papillomavirus infection · See more »
Human T-lymphotropic virus
The human T-lymphotropic virus, human T-cell lymphotropic virus, or human T-cell leukemia-lymphoma virus (HTLV) family of viruses are a group of human retroviruses that are known to cause a type of cancer called adult T-cell leukemia/lymphoma and a demyelinating disease called HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).
New!!: Malignant transformation and Human T-lymphotropic virus · See more »
International Agency for Research on Cancer
The International Agency for Research on Cancer (IARC; Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations.
New!!: Malignant transformation and International Agency for Research on Cancer · See more »
Kaposi's sarcoma-associated herpesvirus
Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus; its formal name according to the International Committee on Taxonomy of Viruses (ICTV) is HHV-8.
New!!: Malignant transformation and Kaposi's sarcoma-associated herpesvirus · See more »
Lesion
A lesion is any abnormal damage or change in the tissue of an organism, usually caused by disease or trauma.
New!!: Malignant transformation and Lesion · See more »
LIG4
DNA ligase 4 is an enzyme that in humans is encoded by the LIG4 gene.
New!!: Malignant transformation and LIG4 · See more »
Medical history
The medical history or case history of a patient is information gained by a physician by asking specific questions, either of the patient or of other people who know the person and can give suitable information, with the aim of obtaining information useful in formulating a diagnosis and providing medical care to the patient.
New!!: Malignant transformation and Medical history · See more »
Melanoma
Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.
New!!: Malignant transformation and Melanoma · See more »
Merkel cell polyomavirus
Merkel cell polyomavirus (MCV or MCPyV) was first described in January 2008 in Pittsburgh, Pennsylvania.
New!!: Malignant transformation and Merkel cell polyomavirus · See more »
MicroRNA
A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.
New!!: Malignant transformation and MicroRNA · See more »
MLH1
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) is a protein that in humans is encoded by the MLH1 gene located on Chromosome 3.
New!!: Malignant transformation and MLH1 · See more »
NEIL1
Endonuclease VIII-like 1 is an enzyme that in humans is encoded by the NEIL1 gene.
New!!: Malignant transformation and NEIL1 · See more »
Nevus
Nevus (or nevi if multiple) is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa.
New!!: Malignant transformation and Nevus · See more »
Nickel
Nickel is a chemical element with symbol Ni and atomic number 28.
New!!: Malignant transformation and Nickel · See more »
Non-coding DNA
In genomics and related disciplines, noncoding DNA sequences are components of an organism's DNA that do not encode protein sequences.
New!!: Malignant transformation and Non-coding DNA · See more »
Non-Hodgkin lymphoma
Non-Hodgkin lymphoma (NHL) is a group of blood cancers that includes all types of lymphoma except Hodgkin's lymphomas.
New!!: Malignant transformation and Non-Hodgkin lymphoma · See more »
Non-small-cell lung carcinoma
Non-small-cell lung carcinoma (NSCLC) is any type of epithelial lung cancer other than small cell lung carcinoma (SCLC).
New!!: Malignant transformation and Non-small-cell lung carcinoma · See more »
Nucleotide excision repair
Nucleotide excision repair is a DNA repair mechanism.
New!!: Malignant transformation and Nucleotide excision repair · See more »
O-6-methylguanine-DNA methyltransferase
O6-alkylguanine DNA alkyltransferase (also known as AGT, MGMT or AGAT) is a protein that in humans is encoded by the O6-methylguanine DNA methyltransferase (MGMT) gene.
New!!: Malignant transformation and O-6-methylguanine-DNA methyltransferase · See more »
Osteosarcoma
An osteosarcoma (OS) or osteogenic sarcoma (OGS) is a cancerous tumor in a bone.
New!!: Malignant transformation and Osteosarcoma · See more »
Oxoguanine glycosylase
8-Oxoguanine glycosylase also known as OGG1 is a DNA glycosylase enzyme that, in humans, is encoded by the OGG1 gene.
New!!: Malignant transformation and Oxoguanine glycosylase · See more »
Pathology
Pathology (from the Ancient Greek roots of pathos (πάθος), meaning "experience" or "suffering" and -logia (-λογία), "study of") is a significant field in modern medical diagnosis and medical research, concerned mainly with the causal study of disease, whether caused by pathogens or non-infectious physiological disorder.
New!!: Malignant transformation and Pathology · See more »
Peripheral blood mononuclear cell
A peripheral blood mononuclear cell (PBMC) is any peripheral blood cell having a round nucleus.
New!!: Malignant transformation and Peripheral blood mononuclear cell · See more »
Promoter (genetics)
In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.
New!!: Malignant transformation and Promoter (genetics) · See more »
Prostate cancer
Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.
New!!: Malignant transformation and Prostate cancer · See more »
Regulation of transcription in cancer
Generally, in progression to cancer, hundreds of genes are silenced or activated.
New!!: Malignant transformation and Regulation of transcription in cancer · See more »
Risk assessment
Risk assessment is the determination of quantitative or qualitative estimate of risk related to a well-defined situation and a recognized threat (also called hazard).
New!!: Malignant transformation and Risk assessment · See more »
RNA-induced silencing complex
The RNA-induced silencing complex, or RISC, is a multiprotein complex, specifically a ribonucleoprotein, which incorporates one strand of a single-stranded RNA (ssRNA) fragment, such as microRNA (miRNA), or double-stranded small interfering RNA (siRNA).
New!!: Malignant transformation and RNA-induced silencing complex · See more »
Somatic (biology)
The term somatic is often used in biology to refer to the cells of the body in contrast to the germ line cells which usually give rise to the gametes (ovum or sperm).
New!!: Malignant transformation and Somatic (biology) · See more »
Stomach cancer
Stomach cancer, also known as gastric cancer, is cancer developing from the lining of the stomach.
New!!: Malignant transformation and Stomach cancer · See more »
Three prime untranslated region
In molecular genetics, the three prime untranslated region (3'-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon.
New!!: Malignant transformation and Three prime untranslated region · See more »
Thyroid cancer
Thyroid cancer is cancer that develops from the tissues of the thyroid gland.
New!!: Malignant transformation and Thyroid cancer · See more »
Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
New!!: Malignant transformation and Transcription (biology) · See more »
Transformation (genetics)
In molecular biology, transformation is the genetic alteration of a cell resulting from the direct uptake and incorporation of exogenous genetic material from its surroundings through the cell membrane(s).
New!!: Malignant transformation and Transformation (genetics) · See more »
Werner syndrome helicase
"Werner syndrome ATP-dependent helicase" also known as DNA helicase, RecQ-like type 3 is an enzyme that in humans is encoded by the WRN gene.
New!!: Malignant transformation and Werner syndrome helicase · See more »
World Health Organization
The World Health Organization (WHO; French: Organisation mondiale de la santé) is a specialized agency of the United Nations that is concerned with international public health.
New!!: Malignant transformation and World Health Organization · See more »
XRCC1
DNA repair protein XRCC1 also known as X-ray repair cross-complementing protein 1 is a protein that in humans is encoded by the XRCC1 gene.
New!!: Malignant transformation and XRCC1 · See more »
Redirects here:
Cell transformation, Malignant Transformation.
References
[1] https://en.wikipedia.org/wiki/Malignant_transformation