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Melanocortin 1 receptor Asp294His

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Asp294His (rs1805009) is a single nucleotide polymorphism (SNP) in the MC1R gene and it is associated with red hair and light skin type. [1]

4 relations: Gene, Melanocortin 1 receptor, Red hair, Single-nucleotide polymorphism.


In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Melanocortin 1 receptor

The melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a G protein–coupled receptor that binds to a class of pituitary peptide hormones known as the melanocortins, which include adrenocorticotropic hormone (ACTH) and the different forms of melanocyte-stimulating hormone (MSH).

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Red hair

Red hair (or ginger hair) occurs naturally in 1–2% of the human population.

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Single-nucleotide polymorphism

A single-nucleotide polymorphism, often abbreviated to SNP (plural), is a variation in a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population (e.g. > 1%).

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Asp294His, Rs1805009.


[1] https://en.wikipedia.org/wiki/Melanocortin_1_receptor_Asp294His

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