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58 relations: Acetylcholine, Acetylcholinesterase, Acetylcholinesterase inhibitor, Actavis, Adapromine, Adverse drug reaction, Agonist, Alpha-7 nicotinic receptor, Alzheimer's disease, Amantadine, Attention deficit hyperactivity disorder, Australian Medicines Handbook, Boston Children's Hospital, British National Formulary, Bromantane, Calcium, Chemical synapse, Cognition, Combination drug, Competition law, Dementia with Lewy bodies, Depolarization, Dissociative, Donepezil, Dopamine receptor D2, Eli Lilly and Company, Eric Schneiderman, Etiology, Excitotoxicity, Forest Laboratories, Generalized anxiety disorder, Glutamic acid, Hypertonia, Kidney, Libido, Liver, Magnesium, Merz Pharma, Micrometre, Migraine, Multiple sclerosis, Neramexane, Neurobiological Technologies, Neuron, Nicotinic acetylcholine receptor, Nitromemantine, NMDA receptor, NMDA receptor antagonist, Nystagmus, Opioid, ..., Pharmacodynamics, Rimantadine, Serotonin, Sigma receptor, Uncompetitive inhibitor, United States Court of Appeals for the Second Circuit, Urinary tract infection, 5-HT3 receptor. Expand index (8 more) »
Acetylcholine
Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells.
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Acetylcholinesterase
Acetylcholinesterase, encoded by HGNC gene ACHE; EC 3.1.1.7) is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
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Acetylcholinesterase inhibitor
An acetylcholinesterase inhibitor (often abbreviated AChEI) or anti-cholinesterase is a chemical or a drug that inhibits the acetylcholinesterase enzyme from breaking down acetylcholine, thereby increasing both the level and duration of action of the neurotransmitter acetylcholine.
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Actavis
Actavis Generics (formerly known as Watson Pharmaceuticals and Actavis PLC, prior to the acquisition of Allergan Inc) is a global pharmaceutical company focused on developing, manufacturing and commercializing branded pharmaceuticals, generic and over-the-counter medicines, and biologic products.
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Adapromine
Adapromine is an antiviral drug of the adamantane group related to amantadine (1-aminoadamantane), rimantadine (1-(1-aminoethyl)adamantane), and memantine (1-amino-3,5-dimethyladamantane) that is marketed in Russia for the treatment and prevention of influenza.
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Adverse drug reaction
An adverse drug reaction (ADR) is an injury caused by taking a medication.
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Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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Alpha-7 nicotinic receptor
The alpha-7 nicotinic receptor, also known as the α7 receptor, is a type of nicotinic acetylcholine receptor implicated in long term memory, consisting entirely of α7 subunits.
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Alzheimer's disease
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.
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Amantadine
Amantadine (trade name Symmetrel, by Endo Pharmaceuticals) is a medication that has U.S. Food and Drug Administration approval for use both as an antiviral and an antiparkinsonian medication.
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Attention deficit hyperactivity disorder
Attention-deficit hyperactivity disorder (ADHD) is a mental disorder of the neurodevelopmental type.
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Australian Medicines Handbook
Australian Medicines Handbook (AMH) is a peer-reviewed medicines prescribing guide for Australian health professionals.
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Boston Children's Hospital
Boston Children's Hospital (called Children's Hospital Boston until 2012) is a 395-licensed-bed children's hospital in the Longwood Medical and Academic Area of Boston, Massachusetts.
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British National Formulary
The British National Formulary (BNF) is a United Kingdom (UK) pharmaceutical reference book that contains a wide spectrum of information and advice on prescribing and pharmacology, along with specific facts and details about many medicines available on the UK National Health Service (NHS).
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Bromantane
Bromantane, sold under the brand name Ladasten, is an atypical psychostimulant and anxiolytic drug of the adamantane family related to amantadine and memantine which is used in Russia in the treatment of neurasthenia.
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Calcium
Calcium is a chemical element with symbol Ca and atomic number 20.
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Chemical synapse
Chemical synapses are biological junctions through which neurons' signals can be exchanged to each other and to non-neuronal cells such as those in muscles or glands.
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Cognition
Cognition is "the mental action or process of acquiring knowledge and understanding through thought, experience, and the senses".
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Combination drug
A combination drug is a fixed-dose combination (FDC) that includes two or more active pharmaceutical ingredients (APIs) combined in a single dosage form, which is manufactured and distributed in fixed doses.
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Competition law
Competition law is a law that promotes or seeks to maintain market competition by regulating anti-competitive conduct by companies.
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Dementia with Lewy bodies
Dementia with Lewy bodies (DLB) is a type of dementia accompanied by changes in behavior, cognition and movement.
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Depolarization
In biology, depolarization is a change within a cell, during which the cell undergoes a shift in electric charge distribution, resulting in less negative charge inside the cell.
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Dissociative
Dissociatives are a class of hallucinogen, which distort perceptions of sight and sound and produce feelings of detachment – dissociation – from the environment and self.
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Donepezil
Donepezil, marketed under the trade name Aricept, is a medication used in the palliative treatment of Alzheimer's disease.
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Dopamine receptor D2
Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.
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Eli Lilly and Company
Eli Lilly and Company is a global pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries.
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Eric Schneiderman
Eric Tradd Schneiderman (born December 31, 1954) is an American lawyer and politician who served as the 65th Attorney General of New York from 2011 until his resignation in May 2018.
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Etiology
Etiology (alternatively aetiology or ætiology) is the study of causation, or origination.
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Excitotoxicity
Excitotoxicity is the pathological process by which nerve cells are damaged or killed by excessive stimulation by neurotransmitters such as glutamate and similar substances.
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Forest Laboratories
Forest Laboratories was a company in the pharmaceutical industry incorporated in Delaware, with its principal office in New York City.
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Generalized anxiety disorder
Generalized anxiety disorder (GAD) is an anxiety disorder characterized by excessive, uncontrollable and often irrational worry, that is, apprehensive expectation about events or activities.
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Glutamic acid
Glutamic acid (symbol Glu or E) is an α-amino acid with formula.
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Hypertonia
Hypertonia is a term sometimes used synonymously with spasticity and rigidity in the literature surrounding damage to the central nervous system, namely upper motor neuron lesions.
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Libido
Libido, colloquially known as sex drive, is a person's overall sexual drive or desire for sexual activity.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Magnesium
Magnesium is a chemical element with symbol Mg and atomic number 12.
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Merz Pharma
Merz Pharma GmbH & Co.
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Micrometre
The micrometre (International spelling as used by the International Bureau of Weights and Measures; SI symbol: μm) or micrometer (American spelling), also commonly known as a micron, is an SI derived unit of length equaling (SI standard prefix "micro-".
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Migraine
A migraine is a primary headache disorder characterized by recurrent headaches that are moderate to severe.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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Neramexane
Neramexane is a drug related to memantine, which acts as an NMDA antagonist and has neuroprotective effects.
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Neurobiological Technologies
Neurobiological Technologies, Inc. ("NTI") was a biotechnology company that was founded in 1987 by Enoch Callaway and John B. Stuppin to in-license and develop drugs primarily to treat neurological conditions; the company was dissolved in 2009 after the failure of its drug candidate ancrod in a Phase III trial for ischemic stroke.
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Neuron
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
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Nicotinic acetylcholine receptor
Nicotinic acetylcholine receptors, or nAChRs, are receptor proteins that respond to the neurotransmitter acetylcholine.
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Nitromemantine
Nitromemantine (developmental code name YQW-36) is a derivative of memantine developed in 2006 for the treatment of Alzheimer's disease.
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NMDA receptor
The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells.
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NMDA receptor antagonist
NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor (NMDAR).
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Nystagmus
Nystagmus is a condition of involuntary (or voluntary, in rare cases) eye movement, acquired in infancy or later in life, that may result in reduced or limited vision.
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Opioid
Opioids are substances that act on opioid receptors to produce morphine-like effects.
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Pharmacodynamics
Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).
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Rimantadine
Rimantadine (INN, sold under the trade name Flumadine) is an orally administered antiviral drug used to treat, and in rare cases prevent, influenzavirus A infection.
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Serotonin
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
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Sigma receptor
Schematic σ receptor The sigma receptors σ1 and σ2 bind to ligands such as 4-PPBP (4-phenyl-1-(4-phenylbutyl) piperidine), SA 4503 (cutamesine), ditolylguanidine, dimethyltryptamine, and siramesine.
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Uncompetitive inhibitor
Uncompetitive inhibition, also known as anti-competitive inhibition, takes place when an enzyme inhibitor binds only to the complex formed between the enzyme and the substrate (the E-S complex).
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United States Court of Appeals for the Second Circuit
The United States Court of Appeals for the Second Circuit (in case citations, 2d Cir.) is one of the thirteen United States Courts of Appeals.
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Urinary tract infection
A urinary tract infection (UTI) is an infection that affects part of the urinary tract.
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5-HT3 receptor
The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin) receptors which are G protein-coupled receptors.
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Redirects here:
ATC code N06DX01, ATCvet code QN06DX01, Abixa, Akatinol, Ebixa, Memantin, Memantine Hydrochloride, Memantine hydrochloride, Mementine, Memox, Namenda, Nemenda.
References
[1] https://en.wikipedia.org/wiki/Memantine
