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Membrane-associated guanylate kinase

Index Membrane-associated guanylate kinase

The membrane-associated guanylate kinases (MAGUK) are a superfamily of proteins. [1]

21 relations: Actin, Adenosine triphosphate, C-terminus, CAMK, Conserved Domain Database, Cytoskeleton, DLG1, DLG2, DLG3, DLG4, DLG5, Guanylate kinase, L27 domain, Microtubule, PDZ domain, Protein, Protein superfamily, Protein–protein interaction, SH3 domain, Signal transduction, WW domain.

Actin

Actin is a family of globular multi-functional proteins that form microfilaments.

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Adenosine triphosphate

Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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CAMK

CAMK, also written as CaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes.

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Conserved Domain Database

The Conserved Domain Database (CDD) is a database of well-annotated multiple sequence alignment models and derived database search models, for ancient domains and full-length proteins.

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Cytoskeleton

A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).

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DLG1

Discs large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a scaffold protein that in humans is encoded by the SAP97 gene.

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DLG2

Disks large homolog 2 (DLG2) also known as channel-associated protein of synapse-110 (chapsyn-110) or postsynaptic density protein 93 (PSD-93) is a protein that in humans is encoded by the DLG2 gene.

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DLG3

Disks large homolog 3 (DLG3) also known as neuroendocrine-DLG or synapse-associated protein 102 (SAP-102) is a protein that in humans is encoded by the DLG3 gene.

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DLG4

PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (discs large homolog 4) gene.

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DLG5

Disks large homolog 5 is a protein that in humans is encoded by the DLG5 gene.

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Guanylate kinase

In enzymology, a guanylate kinase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ATP and GMP, whereas its two products are ADP and GDP.

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L27 domain

The L27 domain is a protein domain that is found in receptor targeting proteins Lin-2 and Lin-7 (LIN7A, LIN7B, LIN7C), as well as some protein kinases and human MPP2 protein.

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Microtubule

Microtubules are tubular polymers of tubulin that form part of the cytoskeleton that provides the cytoplasm of eukaryotic cells and some bacteria with structure and shape.

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PDZ domain

The PDZ domain is a common structural domain of 80-90 amino-acids found in the signaling proteins of bacteria, yeast, plants, viruses and animals.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein superfamily

A protein superfamily is the largest grouping (clade) of proteins for which common ancestry can be inferred (see homology).

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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SH3 domain

The SRC Homology 3 Domain (or SH3 domain) is a small protein domain of about 60 amino acid residues.

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Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.

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WW domain

The WW domain, (also known as the rsp5-domain or WWP repeating motif) is a modular protein domain that mediates specific interactions with protein ligands.

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References

[1] https://en.wikipedia.org/wiki/Membrane-associated_guanylate_kinase

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