69 relations: Alzheimer's disease, Amyloid, Biological membrane, Calcium metabolism, Calcium release activated channel, Calcium signaling, Cardiolipin, Cell membrane, Cell nucleus, Cell signaling, Chloroplast, Copurification, Cytosol, Depolarization, Electron microscope, Endoplasmic reticulum, Endosome, Enzyme, Extracellular signal–regulated kinases, FFAT motif, Golgi apparatus, Homo sapiens, Hydrophile, Hydrophobe, Inner mitochondrial membrane, Integral membrane protein, Ion, JPH1, LiMETER, Lipid, Lipid bilayer fusion, Lipid metabolism, Lipophilicity, Lysosome, Mitochondrion, Muscle contraction, Myocyte, Neurofibrillary tangle, Neuron, ORAI1, Organelle, Organism, OSBP, Oxysterol-binding protein, Pathogenesis, Peroxisome, Phosphatidic acid, Phosphatidylcholine, Phosphatidylinositol, Phosphatidylinositol 4-phosphate, ..., Phospholipid, Plant lipid transfer proteins, Pleckstrin homology domain, Protein, Protein domain, Ryanodine receptor, Saccharomyces cerevisiae, SACM1L, Secretion, Sterol, STIM1, Triad (anatomy), Ultrastructure, Vacuole, VAP protein family, VAPA, Vesicle (biology and chemistry), Voltage-gated calcium channel, Yeast. Expand index (19 more) »
Alzheimer's disease
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.
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Amyloid
Amyloids are aggregates of proteins that become folded into a shape that allows many copies of that protein to stick together forming fibrils.
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Biological membrane
A biological membrane or biomembrane is an enclosing or separating membrane that acts as a selectively permeable barrier within living things.
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Calcium metabolism
Calcium metabolism refers to the movements and regulation of calcium ions (Ca2+) into and out of various body compartments, such as the gastrointestinal tract, the blood plasma, the extracellular and the intracellular fluid, and bone tissue.
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Calcium release activated channel
Calcium release-activated channels (CRAC) are specialized plasma membrane Ca2+ ion channels.
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Calcium signaling
Calcium (Ca2+) ions are important for cellular signalling, as once they enter the cytosol of the cytoplasm they exert allosteric regulatory effects on many enzymes and proteins.
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Cardiolipin
Cardiolipin (IUPAC name "1,3-bis(sn-3’-phosphatidyl)-sn-glycerol") is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Cell signaling
Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions.
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Chloroplast
Chloroplasts are organelles, specialized compartments, in plant and algal cells.
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Copurification
Copurification in a chemical or biochemical context is the physical separation by chromatography or other purification technique of two or more substances of interest from other contaminating substances.
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Cytosol
The cytosol, also known as intracellular fluid (ICF) or cytoplasmic matrix, is the liquid found inside cells.
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Depolarization
In biology, depolarization is a change within a cell, during which the cell undergoes a shift in electric charge distribution, resulting in less negative charge inside the cell.
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Electron microscope
An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination.
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Endoplasmic reticulum
The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.
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Endosome
In cell biology, an endosome is a membrane-bound compartment inside eukaryotic cells.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Extracellular signal–regulated kinases
In molecular biology, extracellular signal–regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
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FFAT motif
A FFAT motif (FFAT being an acronym for two phenylalanines (FF) in an Acidic Tract) is a protein sequence motif of six defined amino acids plus neighbouring residues that binds to proteins in the VAP protein family.
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Golgi apparatus
The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells.
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Homo sapiens
Homo sapiens is the systematic name used in taxonomy (also known as binomial nomenclature) for the only extant human species.
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Hydrophile
A hydrophile is a molecule or other molecular entity that is attracted to water molecules and tends to be dissolved by water.
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Hydrophobe
In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.
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Inner mitochondrial membrane
The inner mitochondrial membrane (IMM) is the mitochondrial membrane which separates the mitochondrial matrix from the intermembrane space.
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Integral membrane protein
An integral membrane protein (IMP) is a type of membrane protein that is permanently attached to the biological membrane.
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Ion
An ion is an atom or molecule that has a non-zero net electrical charge (its total number of electrons is not equal to its total number of protons).
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JPH1
Junctophilin-1 is a protein that in humans is encoded by the JPH1 gene.
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LiMETER
LiMETER stands for light-inducible membrane-tethered peripheral endoplasmic reticulum (ER).
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Lipid
In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.
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Lipid bilayer fusion
In membrane biology, fusion is the process by which two initially distinct lipid bilayers merge their hydrophobic cores, resulting in one interconnected structure.
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Lipid metabolism
Lipid metabolism is the synthesis and degradation of lipids in cells, involving the break down or storage of fats for energy.
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Lipophilicity
Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene.
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Lysosome
A lysosome is a membrane-bound organelle found in nearly all animal cells.
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Mitochondrion
The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.
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Muscle contraction
Muscle contraction is the activation of tension-generating sites within muscle fibers.
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Myocyte
A myocyte (also known as a muscle cell) is the type of cell found in muscle tissue.
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Neurofibrillary tangle
Neurofibrillary tangles (NFTs) are aggregates of hyperphosphorylated tau protein that are most commonly known as a primary marker of Alzheimer's disease.
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Neuron
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
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ORAI1
Calcium release-activated calcium channel protein 1 is a calcium selective ion channel that in humans is encoded by the ORAI1 gene.
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Organelle
In cell biology, an organelle is a specialized subunit within a cell that has a specific function, in which their function is vital for the cell to live.
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Organism
In biology, an organism (from Greek: ὀργανισμός, organismos) is any individual entity that exhibits the properties of life.
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OSBP
Oxysterol-binding protein 1 is a protein that in humans is encoded by the OSBP gene.
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Oxysterol-binding protein
The oxysterol-binding protein (OSBP)-related proteins (ORPs) are a family of lipid transfer proteins (LTPs).
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Pathogenesis
The pathogenesis of a disease is the biological mechanism (or mechanisms) that leads to the diseased state.
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Peroxisome
A peroxisome is a type of organelle known as a microbody, found in virtually all eukaryotic cells.
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Phosphatidic acid
Phosphatidic acids are phospholipids which on hydrolysis give rise to one molecule of glycerol and phosphoric acid and two molecules of fatty acids.
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Phosphatidylcholine
Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup.
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Phosphatidylinositol
Phosphatidylinositol consists of a family of lipids as illustrated on the right, a class of the phosphatidylglycerides.
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Phosphatidylinositol 4-phosphate
Phosphatidylinositol 4-phosphate (PtdIns4P, PI-4-P, PI4P, or PIP) is a precursor of phosphatidylinositol (4,5)-bisphosphate.
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Phospholipid
Phospholipids are a class of lipids that are a major component of all cell membranes.
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Plant lipid transfer proteins
Plant lipid transfer proteins, also known as plant LTPs or PLTPs, are a group of highly-conserved proteins of about 7-9kDa found in higher plant tissues.
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Pleckstrin homology domain
Pleckstrin homology domain (PH domain) is a protein domain of approximately 120 amino acids that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
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Ryanodine receptor
Ryanodine receptors (RyRs) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons.
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Saccharomyces cerevisiae
Saccharomyces cerevisiae is a species of yeast.
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SACM1L
Phosphatidylinositide phosphatase SAC1 is an enzyme that in humans is encoded by the SACM1L gene.
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Secretion
Secretion is the movement of material from one point to another, e.g. secreted chemical substance from a cell or gland.
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Sterol
Sterols, also known as steroid alcohols, are a subgroup of the steroids and an important class of organic molecules.
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STIM1
Stromal interaction molecule 1 is a protein that in humans is encoded by the STIM1 gene.
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Triad (anatomy)
In the histology of skeletal muscle, a triad is the structure formed by a T tubule with a sarcoplasmic reticulum (SR) known as the terminal cisterna on either side.
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Ultrastructure
Ultrastructure (or ultra-structure) is the architecture of cells that is visible at higher magnifications than found on a standard optical light microscope.
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Vacuole
A vacuole is a membrane-bound organelle which is present in all plant and fungal cells and some protist, animal and bacterial cells.
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VAP protein family
VAP proteins are conserved integral membrane proteins of the endoplasmic reticulum found in all eukaryotic cells.
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VAPA
Vesicle-associated membrane protein-associated protein A is a protein that in humans is encoded by the VAPA gene.
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Vesicle (biology and chemistry)
In cell biology, a vesicle is a small structure within a cell, or extracellular, consisting of fluid enclosed by a lipid bilayer.
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Voltage-gated calcium channel
Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca2+.
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Yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.
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References
[1] https://en.wikipedia.org/wiki/Membrane_contact_site