Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Free
Faster access than browser!
 

Mercaptopurine

+ Save concept

Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. [1]

68 relations: Abortifacient, Acute lymphoblastic leukemia, Adenosine monophosphate, Adverse drug reaction, Allopurinol, Amidophosphoribosyltransferase, Antimetabolite, Autoimmune disease, Azathioprine, Bone marrow, Bone marrow suppression, Breathing, Cancer, Chemical weapon, Chromosome, Chronic myelogenous leukemia, Cornelius P. Rhoads, Crohn's disease, Cytotoxicity, Developing country, Dizziness, DNA, Fever, Genetic testing, Genetic variation, George H. Hitchings, Gertrude B. Elion, GlaxoSmithKline, Guanine, Health system, Hepatotoxicity, Human feces, Hypoxanthine, Hypoxanthine-guanine phosphoribosyltransferase, Immunization, Inosinic acid, Itch, Kidney, Melena, Memorial Sloan Kettering Cancer Center, Methotrexate, Methylation, National Health Service, Nitrogen mustard, Nucleotide, NUDT15, Pancreatitis, Pharmacogenetics, Poliomyelitis, Pregnancy, ..., Purine, Rash, Red blood cell, RNA, Sore throat, Swelling (medical), Thiopurine, Thiopurine methyltransferase, Tuckahoe (village), New York, Ulcerative colitis, Urine, Vaccination, Vacuum aspiration, White blood cell, WHO Model List of Essential Medicines, Xanthine oxidase, Xanthosine monophosphate, Zygosity. Expand index (18 more) »

Abortifacient

An abortifacient ("that which will cause a miscarriage" from Latin: abortus "miscarriage" and faciens "making") is a substance that induces abortion.

New!!: Mercaptopurine and Abortifacient · See more »

Acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes.

New!!: Mercaptopurine and Acute lymphoblastic leukemia · See more »

Adenosine monophosphate

Adenosine monophosphate (AMP), also known as 5'-adenylic acid, is a nucleotide.

New!!: Mercaptopurine and Adenosine monophosphate · See more »

Adverse drug reaction

An adverse drug reaction (ADR) is an injury caused by taking a medication.

New!!: Mercaptopurine and Adverse drug reaction · See more »

Allopurinol

Allopurinol, sold under the brand name Zyloprim among others, is a medication used to decrease high blood uric acid levels.

New!!: Mercaptopurine and Allopurinol · See more »

Amidophosphoribosyltransferase

Amidophosphoribosyltransferase (ATase), also known as glutamine phosphoribosylpyrophosphate amidotransferase (GPAT), is an enzyme responsible for catalyzing the conversion of 5-phosphoribosyl-1-pyrophosphate (PRPP) into 5-phosphoribosyl-1-amine (PRA), using the ammonia group from a glutamine side-chain.

New!!: Mercaptopurine and Amidophosphoribosyltransferase · See more »

Antimetabolite

An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism.

New!!: Mercaptopurine and Antimetabolite · See more »

Autoimmune disease

An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.

New!!: Mercaptopurine and Autoimmune disease · See more »

Azathioprine

Azathioprine (AZA), sold under the brand name Imuran among others, is an immunosuppressive medication.

New!!: Mercaptopurine and Azathioprine · See more »

Bone marrow

Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.

New!!: Mercaptopurine and Bone marrow · See more »

Bone marrow suppression

Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).

New!!: Mercaptopurine and Bone marrow suppression · See more »

Breathing

Breathing (or respiration, or ventilation) is the process of moving air into and out of the lungs to facilitate gas exchange with the internal environment, mostly by bringing in oxygen and flushing out carbon dioxide.

New!!: Mercaptopurine and Breathing · See more »

Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

New!!: Mercaptopurine and Cancer · See more »

Chemical weapon

A chemical weapon (CW) is a specialized munition that uses chemicals formulated to inflict death or harm on humans.

New!!: Mercaptopurine and Chemical weapon · See more »

Christmas

Christmas is an annual festival commemorating the birth of Jesus Christ,Martindale, Cyril Charles.

New!!: Mercaptopurine and Christmas · See more »

Christmas and holiday season

The Christmas season, also called the festive season, or the holiday season (mainly in the U.S. and Canada; often simply called the holidays),, is an annually recurring period recognized in many Western and Western-influenced countries that is generally considered to run from late November to early January.

New!!: Mercaptopurine and Christmas and holiday season · See more »

Christmas Eve

Christmas Eve is the evening or entire day before Christmas Day, the festival commemorating the birth of Jesus.

New!!: Mercaptopurine and Christmas Eve · See more »

Christmas traditions

Christmas traditions vary from country to country.

New!!: Mercaptopurine and Christmas traditions · See more »

Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

New!!: Mercaptopurine and Chromosome · See more »

Chronic myelogenous leukemia

Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells.

New!!: Mercaptopurine and Chronic myelogenous leukemia · See more »

Cornelius P. Rhoads

Cornelius Packard "Dusty" Rhoads (June 9, 1898 – August 13, 1959) was an American pathologist, oncologist, and hospital administrator.

New!!: Mercaptopurine and Cornelius P. Rhoads · See more »

Crohn's disease

Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.

New!!: Mercaptopurine and Crohn's disease · See more »

Cytotoxicity

Cytotoxicity is the quality of being toxic to cells.

New!!: Mercaptopurine and Cytotoxicity · See more »

Developing country

A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.

New!!: Mercaptopurine and Developing country · See more »

Dizziness

Dizziness is an impairment in spatial perception and stability.

New!!: Mercaptopurine and Dizziness · See more »

DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

New!!: Mercaptopurine and DNA · See more »

Fever

Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point.

New!!: Mercaptopurine and Fever · See more »

Genetic testing

Genetic testing, also known as DNA testing, allows the determination of bloodlines and the genetic diagnosis of vulnerabilities to inherited diseases.

New!!: Mercaptopurine and Genetic testing · See more »

Genetic variation

Genetic variation means that biological systems – individuals and populations – are different over space.

New!!: Mercaptopurine and Genetic variation · See more »

George H. Hitchings

George Herbert Hitchings (April 18, 1905 – February 27, 1998) was an American doctor who shared the 1988 Nobel Prize in Physiology or Medicine with Sir James Black and Gertrude Elion "for their discoveries of important principles for drug treatment," Hitchings specifically for his work on chemotherapy.

New!!: Mercaptopurine and George H. Hitchings · See more »

Gertrude B. Elion

Gertrude Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, who shared the 1988 Nobel Prize in Physiology or Medicine with George H. Hitchings and Sir James Black.

New!!: Mercaptopurine and Gertrude B. Elion · See more »

GlaxoSmithKline

GlaxoSmithKline plc (GSK) is a British pharmaceutical company headquartered in Brentford, London.

New!!: Mercaptopurine and GlaxoSmithKline · See more »

Guanine

Guanine (or G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).

New!!: Mercaptopurine and Guanine · See more »

Health system

A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.

New!!: Mercaptopurine and Health system · See more »

Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.

New!!: Mercaptopurine and Hepatotoxicity · See more »

Human feces

Human feces (or faeces in British English; fæx) are the solid or semisolid remains of the food that could not be digested or absorbed in the small intestine, but has been rotted down by bacteria in the large intestine.

New!!: Mercaptopurine and Human feces · See more »

Hypoxanthine

Hypoxanthine is a naturally occurring purine derivative.

New!!: Mercaptopurine and Hypoxanthine · See more »

Hypoxanthine-guanine phosphoribosyltransferase

Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene.

New!!: Mercaptopurine and Hypoxanthine-guanine phosphoribosyltransferase · See more »

Immunization

Immunization, or immunisation, is the process by which an individual's immune system becomes fortified against an agent (known as the immunogen).

New!!: Mercaptopurine and Immunization · See more »

Inosinic acid

Inosinic acid or inosine monophosphate (IMP) is a nucleoside monophosphate.

New!!: Mercaptopurine and Inosinic acid · See more »

Itch

Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.

New!!: Mercaptopurine and Itch · See more »

Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

New!!: Mercaptopurine and Kidney · See more »

Melena

Melena or melæna refers to the dark black, tarry feces that are associated with upper gastrointestinal bleeding.

New!!: Mercaptopurine and Melena · See more »

Memorial Sloan Kettering Cancer Center

Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in New York City, founded in 1884 as the New York Cancer Hospital.

New!!: Mercaptopurine and Memorial Sloan Kettering Cancer Center · See more »

Methotrexate

Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant.

New!!: Mercaptopurine and Methotrexate · See more »

Methylation

In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.

New!!: Mercaptopurine and Methylation · See more »

National Health Service

The National Health Service (NHS) is the name used for each of the public health services in the United Kingdom – the National Health Service in England, NHS Scotland, NHS Wales, and Health and Social Care in Northern Ireland – as well as a term to describe them collectively.

New!!: Mercaptopurine and National Health Service · See more »

New Year

New Year is the time or day at which a new calendar year begins and the calendar's year count increments by one.

New!!: Mercaptopurine and New Year · See more »

New Year's Day

New Year's Day, also called simply New Year's or New Year, is observed on January 1, the first day of the year on the modern Gregorian calendar as well as the Julian calendar.

New!!: Mercaptopurine and New Year's Day · See more »

New Year's Eve

In the Gregorian calendar, New Year's Eve (also known as Old Year's Day or Saint Sylvester's Day in many countries), the last day of the year, is on 31 December which is the seventh day of Christmastide.

New!!: Mercaptopurine and New Year's Eve · See more »

Nitrogen mustard

Nitrogen mustards are cytotoxic chemotherapy agents derived from mustard gas.

New!!: Mercaptopurine and Nitrogen mustard · See more »

Nucleotide

Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.

New!!: Mercaptopurine and Nucleotide · See more »

NUDT15

Nudix hydrolase 15 is a protein that in humans is encoded by the NUDT15 gene.

New!!: Mercaptopurine and NUDT15 · See more »

Pancreatitis

Pancreatitis is inflammation of the pancreas.

New!!: Mercaptopurine and Pancreatitis · See more »

Pharmacogenetics

Pharmacogenetics is the study of inherited genetic differences in drug metabolic pathways which can affect individual responses to drugs, both in terms of therapeutic effect as well as adverse effects.

New!!: Mercaptopurine and Pharmacogenetics · See more »

Poliomyelitis

Poliomyelitis, often called polio or infantile paralysis, is an infectious disease caused by the poliovirus.

New!!: Mercaptopurine and Poliomyelitis · See more »

Pregnancy

Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.

New!!: Mercaptopurine and Pregnancy · See more »

Purine

A purine is a heterocyclic aromatic organic compound that consists of a pyrimidine ring fused to an imidazole ring.

New!!: Mercaptopurine and Purine · See more »

Rash

A rash is a change of the human skin which affects its color, appearance, or texture.

New!!: Mercaptopurine and Rash · See more »

Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

New!!: Mercaptopurine and Red blood cell · See more »

RNA

Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.

New!!: Mercaptopurine and RNA · See more »

Sore throat

Sore throat, also known as throat pain, is pain or irritation of the throat.

New!!: Mercaptopurine and Sore throat · See more »

Swelling (medical)

In medical parlance, swelling, turgescence or tumefaction is a transient abnormal enlargement of a body part or area not caused by proliferation of cells.

New!!: Mercaptopurine and Swelling (medical) · See more »

Thiopurine

The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis), and organ transplant recipients.

New!!: Mercaptopurine and Thiopurine · See more »

Thiopurine methyltransferase

Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT) is an enzyme that in humans is encoded by the TPMT gene.

New!!: Mercaptopurine and Thiopurine methyltransferase · See more »

Tuckahoe (village), New York

Tuckahoe is a village in the town of Eastchester in Westchester County, New York, United States.

New!!: Mercaptopurine and Tuckahoe (village), New York · See more »

Ulcerative colitis

Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.

New!!: Mercaptopurine and Ulcerative colitis · See more »

Urine

Urine is a liquid by-product of metabolism in humans and in many animals.

New!!: Mercaptopurine and Urine · See more »

Vaccination

Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual's immune system to develop adaptive immunity to a pathogen.

New!!: Mercaptopurine and Vaccination · See more »

Vacuum aspiration

Vacuum or suction aspiration uses aspiration to remove uterine contents through the cervix.

New!!: Mercaptopurine and Vacuum aspiration · See more »

White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

New!!: Mercaptopurine and White blood cell · See more »

WHO Model List of Essential Medicines

The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.

New!!: Mercaptopurine and WHO Model List of Essential Medicines · See more »

Xanthine oxidase

Xanthine oxidase (XO, sometimes XAO) is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species.

New!!: Mercaptopurine and Xanthine oxidase · See more »

Xanthosine monophosphate

Xanthosine monophosphate is an intermediate in purine metabolism.

New!!: Mercaptopurine and Xanthosine monophosphate · See more »

Zygosity

Zygosity is the degree of similarity of the alleles for a trait in an organism.

New!!: Mercaptopurine and Zygosity · See more »

2018

2018 has been designated as the third International Year of the Reef by the International Coral Reef Initiative.

New!!: Mercaptopurine and 2018 · See more »

2019

2019 (MMXIX) will be a common year starting on Tuesday of the Gregorian calendar, the 2019th year of the Common Era (CE) and Anno Domini (AD) designations, the 19th year of the 3rd millennium, the 19th year of the 21st century, and the 10th and last year of the 2010s decade.

New!!: Mercaptopurine and 2019 · See more »

Redirects here:

6 MP, 6 mercaptopurine, 6-MP, 6-Mercaptopurine, 6-mercaptopurine, 6MP, ATC code L01BB02, ATCvet code QL01BB02, Ismipur, Leukerin, Leupurin, Mercaleukim, Mercaleukin, Puri-Nethol, Purimethol, Purinethiol, Purinethol, Purinetol.

References

[1] https://en.wikipedia.org/wiki/Mercaptopurine

OutgoingIncoming
Hey! We are on Facebook now! »