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42 relations: Burkitt's lymphoma, Cell membrane, Cervical cancer, Clade, Complementary DNA, Digital transcriptome subtraction, DNA sequencing, DNA virus, Etiology, Eukaryotic translation, Helicase, HIV/AIDS, HPV vaccines, Immunodeficiency, International Agency for Research on Cancer, Kaposi's sarcoma, Kaposi's sarcoma-associated herpesvirus, Large tumor antigen, Merkel cell, Merkel-cell carcinoma, Messenger RNA, Metagenomics, Monoclonal, Murine polyomavirus, Mutagen, Neuroectodermal tumor, Oncogene, Oncovirus, Organ transplantation, Patrick S. Moore, Pittsburgh, Polymerase chain reaction, Polyomaviridae, Retinoblastoma protein, RNA interference, Skin cancer, Southern blot, Survivin, SV40, Tumor suppressor, Ultraviolet, Yuan Chang.
Burkitt's lymphoma
Burkitt lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Cervical cancer
Cervical cancer is a cancer arising from the cervix.
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Clade
A clade (from κλάδος, klados, "branch"), also known as monophyletic group, is a group of organisms that consists of a common ancestor and all its lineal descendants, and represents a single "branch" on the "tree of life".
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Complementary DNA
In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.
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Digital transcriptome subtraction
Digital transcriptome subtraction (DTS) is a bioinformatics method to detect the presence of novel pathogen transcripts through computational removal of the host sequences.
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DNA sequencing
DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule.
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DNA virus
A DNA virus is a virus that has DNA as its genetic material and replicates using a DNA-dependent DNA polymerase.
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Etiology
Etiology (alternatively aetiology or ætiology) is the study of causation, or origination.
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Eukaryotic translation
Eukaryotic translation is the biological process by which messenger RNA is translated into proteins in eukaryotes.
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Helicase
Helicases are a class of enzymes vital to all living organisms.
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HIV/AIDS
Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).
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HPV vaccines
Human papilloma virus (HPV) vaccines are vaccines that prevent infection by certain types of human papillomavirus.
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Immunodeficiency
Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent.
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International Agency for Research on Cancer
The International Agency for Research on Cancer (IARC; Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations.
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Kaposi's sarcoma
Kaposi's sarcoma (KS) is a type of cancer that can form masses in the skin, lymph nodes, or other organs.
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Kaposi's sarcoma-associated herpesvirus
Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus; its formal name according to the International Committee on Taxonomy of Viruses (ICTV) is HHV-8.
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Large tumor antigen
The large tumor antigen (also called the large T-antigen and abbreviated LTag or LT) is a protein encoded in the genomes of polyomaviruses, which are small double-stranded DNA viruses.
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Merkel cell
Merkel cells, also known as Merkel-Ranvier cells or tactile epithelial cells, are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates.
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Merkel-cell carcinoma
Merkel-cell carcinoma (MCC) is a rare and highly aggressive skin cancer, which, in most cases, is caused by the Merkel cell polyomavirus (MCV) discovered by scientists at the University of Pittsburgh in 2008.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental samples.
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Monoclonal
Monoclonal cells are a group of cells produced from a single ancestral cell by repeated cellular replication.
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Murine polyomavirus
Murine polyomavirus (also known as mouse polyomavirus, Polyomavirus muris, or Mus musculus polyomavirus 1, and in older literature as SE polyoma or parotid tumor virus; abbreviated MPyV) is an unenveloped double-stranded DNA virus of the polyomavirus family.
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Mutagen
In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level.
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Neuroectodermal tumor
A neuroectodermal tumor is a tumor of the central or peripheral nervous system.
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Oncogene
An oncogene is a gene that has the potential to cause cancer.
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Oncovirus
An oncovirus is a virus that can cause cancer.
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Organ transplantation
Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ.
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Patrick S. Moore
Patrick S. Moore (born October 21, 1956) is an Irish and American virologist and epidemiologist who co-discovered together with his wife, Yuan Chang, two different human viruses causing the AIDS-related cancer Kaposi's sarcoma and the skin cancer Merkel cell carcinoma.
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Pittsburgh
Pittsburgh is a city in the Commonwealth of Pennsylvania in the United States, and is the county seat of Allegheny County.
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Polymerase chain reaction
Polymerase chain reaction (PCR) is a technique used in molecular biology to amplify a single copy or a few copies of a segment of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.
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Polyomaviridae
Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds.
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Retinoblastoma protein
The retinoblastoma protein (protein name abbreviated pRb; gene name abbreviated RB or RB1) is a tumor suppressor protein that is dysfunctional in several major cancers.
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RNA interference
RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules.
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Skin cancer
Skin cancers are cancers that arise from the skin.
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Southern blot
A Southern blot is a method used in molecular biology for detection of a specific DNA sequence in DNA samples.
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Survivin
Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene.
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SV40
SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans.
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Tumor suppressor
A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.
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Ultraviolet
Ultraviolet (UV) is electromagnetic radiation with a wavelength from 10 nm to 400 nm, shorter than that of visible light but longer than X-rays.
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Yuan Chang
Yuan Chang (born 17 November 1959) is an American virologist and pathologist who co-discovered Kaposi's sarcoma-associated herpesvirus (KSHV) and Merkel cell polyomavirus, two of the seven known human oncoviruses.
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Redirects here:
Merkel Cell Polyomavirus, Merkel cell virus.
References
[1] https://en.wikipedia.org/wiki/Merkel_cell_polyomavirus
