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Metapristone (developmental code name RU-42633; also known as desmethylmifepristone) is the major metabolite of mifepristone (RU-486, RU-38486) and a selective progesterone receptor modulator (SPRM) which itself was never marketed. [1]

13 relations: Cancer, Chemotherapy, CYP3A4, Demethylation, Enzyme, Glucocorticoid receptor, Ligand (biochemistry), Liver, Metabolite, Metastasis, Mifepristone, Progesterone receptor, Selective progesterone receptor modulator.


Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.

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Christmas is an annual festival commemorating the birth of Jesus Christ,Martindale, Cyril Charles.

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Christmas and holiday season

The Christmas season, also called the festive season, or the holiday season (mainly in the U.S. and Canada; often simply called the holidays),, is an annually recurring period recognized in many Western and Western-influenced countries that is generally considered to run from late November to early January.

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Christmas Eve

Christmas Eve is the evening or entire day before Christmas Day, the festival commemorating the birth of Jesus.

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Christmas traditions

Christmas traditions vary from country to country.

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Demethylation is the chemical process resulting in the removal of a methyl group (CH3) from a molecule.

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Enzymes are macromolecular biological catalysts.

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Glucocorticoid receptor

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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A metabolite is the intermediate end product of metabolism.

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Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.

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Mifepristone, also known as RU-486, is a medication typically used in combination with misoprostol, to bring about an abortion.

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New Year

New Year is the time or day at which a new calendar year begins and the calendar's year count increments by one.

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New Year's Day

New Year's Day, also called simply New Year's or New Year, is observed on January 1, the first day of the year on the modern Gregorian calendar as well as the Julian calendar.

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New Year's Eve

In the Gregorian calendar, New Year's Eve (also known as Old Year's Day or Saint Sylvester's Day in many countries), the last day of the year, is on 31 December which is the seventh day of Christmastide.

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Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.

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Selective progesterone receptor modulator

A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor.

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2018 has been designated as the third International Year of the Reef by the International Coral Reef Initiative.

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2019 (MMXIX) will be a common year starting on Tuesday of the Gregorian calendar, the 2019th year of the Common Era (CE) and Anno Domini (AD) designations, the 19th year of the 3rd millennium, the 19th year of the 21st century, and the 10th and last year of the 2010s decade.

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Redirects here:

C28H33NO2, Demethylmifepristone, Desmethylmifepristone, Monodemethylmifepristone, Monodesmethylmifepristone, N-Demethylmifepristone, N-Desmethylmifepristone, N-demethylmifepristone, N-desmethylmifepristone, R 42,633, R 42633, R-42,633, R-42633, R42633, RU 42,633, RU 42633, RU-42,633, RU-42633, RU42633.


[1] https://en.wikipedia.org/wiki/Metapristone

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