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122 relations: Abortifacient, Abortion, Acute lymphoblastic leukemia, Adenosine, Amine, Aminoglycoside, Aminopterin, Anticonvulsant, Antifolate, Antimetabolite, Aspirin, Autoimmune disease, B cell, Blood–brain barrier, Breast cancer, Breastfeeding, Cancer, Cerebrospinal fluid, Chemotherapy, Choriocarcinoma, Ciclosporin, Cisplatin, Colestyramine, Complete blood count, Creatinine, Crohn's disease, Dantrolene, De novo synthesis, Dermatitis, Developing country, Dihydrofolate reductase, Dihydrofolic acid, Dilation and curettage, Disease-modifying antirheumatic drug, DNA, DNA replication, Ectopic pregnancy, Enzyme, Fas receptor, Folate, Generic drug, Health system, Hepatotoxicity, Immunosuppression, Intercellular adhesion molecule, Interleukin 1 beta, Intramuscular injection, Intrathecal administration, Intravenous therapy, Invasive hydatidiform mole, ..., Jane C. Wright, Juvenile dermatomyositis, Kidney failure, Leukemia, Leukoencephalopathy, Leukopenia, Liver, Liver disease, Liver function tests, Lung cancer, Lymphoma, Mechanism of action, Methylation, Min Chiu Li, Misoprostol, Molar pregnancy, Multiple sclerosis, Mycosis fungoides, Myelopathy, Myocardial infarction, Neomycin, Neoplasm, Nitrous oxide, Nonsteroidal anti-inflammatory drug, Nucleoside, Omeprazole, Osteosarcoma, OxfordDictionaries.com, Paracetamol, Paromomycin, Penicillin, Pneumonitis, Post-chemotherapy cognitive impairment, Pregnancy, Pregnancy category, Probenecid, Protein, Proton-pump inhibitor, Psoriasis, Psoriatic arthritis, Pulmonary fibrosis, Purine, Purine metabolism, Pyrimidine, Pyrimidone, Respiratory disease, Retinoid, Rheumatoid arthritis, RNA, Sarcoidosis, Sidney Farber, Stomatitis, Stroke, Structural analog, Subcutaneous injection, Systemic lupus erythematosus, T cell, Teratology, Tetrahydrofolic acid, The Economist, Therapeutic index, Thymidine, Thymidine monophosphate, TNF inhibitor, Trimethoprim, Trophoblastic neoplasm, Tumors of the hematopoietic and lymphoid tissues, Ulcerative colitis, Valproate, Vasculitis, WHO Model List of Essential Medicines, Yellapragada Subbarow. Expand index (72 more) »
Abortifacient
An abortifacient ("that which will cause a miscarriage" from Latin: abortus "miscarriage" and faciens "making") is a substance that induces abortion.
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Abortion
Abortion is the ending of pregnancy by removing an embryo or fetus before it can survive outside the uterus.
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Acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes.
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Adenosine
Adenosine is both a chemical found in many living systems and a medication.
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Amine
In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.
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Aminoglycoside
Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial therapeutic agents that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside (sugar); the term can also refer more generally to any organic molecule that contains aminosugar substructures.
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Aminopterin
Aminopterin (or 4-aminopteroic acid), the 4-amino derivative of folic acid, is an antineoplastic drug with immunosuppressive properties often used in chemotherapy.
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Anticonvulsant
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.
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Antifolate
Antifolates are a class of antimetabolite medications that antagonise (that is, block) the actions of folic acid (vitamin B9).
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Antimetabolite
An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism.
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Aspirin
Aspirin, also known as acetylsalicylic acid (ASA), is a medication used to treat pain, fever, or inflammation.
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Autoimmune disease
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.
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B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
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Blood–brain barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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Breastfeeding
Breastfeeding, also known as nursing, is the feeding of babies and young children with milk from a woman's breast.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Cerebrospinal fluid
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found in the brain and spinal cord.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Choriocarcinoma
Choriocarcinoma is a malignant, trophoblastic cancer, usually of the placenta.
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Ciclosporin
Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product.
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Cisplatin
Cisplatin is a chemotherapy medication used to treat a number of cancers.
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Colestyramine
Colestyramine (INN) or cholestyramine (USAN) (trade names Questran, Questran Light, Cholybar, Olestyr) is a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption.
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Complete blood count
A complete blood count (CBC), also known as a complete blood cell count, full blood count (FBC), or full blood exam (FBE), is a blood panel requested by a doctor or other medical professional that gives information about the cells in a patient's blood, such as the cell count for each cell type and the concentrations of various proteins and minerals.
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Creatinine
Creatinine (or; from flesh) is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass).
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Crohn's disease
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.
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Dantrolene
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells.
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De novo synthesis
De novo synthesis refers to the synthesis of complex molecules from simple molecules such as sugars or amino acids, as opposed to recycling after partial degradation.
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Dermatitis
Dermatitis, also known as eczema, is a group of diseases that results in inflammation of the skin.
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Developing country
A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.
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Dihydrofolate reductase
Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.
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Dihydrofolic acid
Dihydrofolic acid (conjugate base dihydrofolate) (DHF) is a folic acid (vitamin B9) derivative which is converted to tetrahydrofolic acid by dihydrofolate reductase.
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Dilation and curettage
Dilation (or dilatation) and curettage (D&C) refers to the dilation (widening/opening) of the cervix and surgical removal of part of the lining of the uterus and/or contents of the uterus by scraping and scooping (curettage).
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Disease-modifying antirheumatic drug
Disease-modifying antirheumatic drugs (DMARDs) is a category of otherwise unrelated drugs defined by their use in rheumatoid arthritis to slow down disease progression.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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DNA replication
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.
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Ectopic pregnancy
Ectopic pregnancy is a complication of pregnancy in which the embryo attaches outside the uterus.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Fas receptor
The first apoptosis signal receptor (Fas or FasR), also known as apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6) is a protein that in humans is encoded by the FAS gene.
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Folate
Folate, distinct forms of which are known as folic acid, folacin, and vitamin B9, is one of the B vitamins.
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Generic drug
A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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Hepatotoxicity
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.
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Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system.
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Intercellular adhesion molecule
In molecular biology, intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily.
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Interleukin 1 beta
Interleukin 1 beta (IL1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene.
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Intramuscular injection
Intramuscular (also IM or im) injection is the injection of a substance directly into muscle.
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Intrathecal administration
Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF) and is useful in spinal anaesthesia, chemotherapy, or pain management applications.
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Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
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Invasive hydatidiform mole
Invasive hydatidiform mole, also known as invasive mole and chorioadenoma destruens is a type of neoplasia that grows into the muscular wall of the uterus.
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Jane C. Wright
Jane Cooke Wright (also known as "Jane Jones" or "Mr. David Jones") (November 30, 1919 – February 19, 2013) was a pioneering cancer researcher and surgeon noted for her contributions to chemotherapy.
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Juvenile dermatomyositis
Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications.
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Kidney failure
Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys no longer work.
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Leukemia
Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.
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Leukoencephalopathy
The term leukoencephalopathy is a broad term for leukodystrophy-like diseases.
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Leukopenia
Leukopenia is a decrease in the number of white blood cells (leukocytes) found in the blood, which places individuals at increased risk of infection.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Liver disease
Liver disease (also called hepatic disease) is a type of damage to or disease of the liver.
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Liver function tests
Liver function tests (LFTs or LFs) are groups of blood tests that give information about the state of a patient's liver.
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Lung cancer
Lung cancer, also known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung.
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Lymphoma
Lymphoma is a group of blood cancers that develop from lymphocytes (a type of white blood cell).
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Mechanism of action
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.
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Methylation
In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.
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Min Chiu Li
Min Chiu Li (1919–1980) was a Chinese-American oncologist and cancer researcher.
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Misoprostol
Misoprostol, sold under the brandname Cytotec among others, is a medication used to start labor, cause an abortion, prevent and treat stomach ulcers, and treat postpartum bleeding due to poor contraction of the uterus.
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Molar pregnancy
Molar pregnancy is an abnormal form of pregnancy in which a non-viable fertilized egg implants in the uterus and will fail to come to term.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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Mycosis fungoides
Mycosis fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides, is the most common form of cutaneous T-cell lymphoma.
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Myelopathy
Myelopathy describes any neurologic deficit related to the spinal cord.
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Myocardial infarction
Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.
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Neomycin
Neomycin is an aminoglycoside antibiotic found in many topical medications such as creams, ointments, and eyedrops.
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Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
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Nitrous oxide
Nitrous oxide, commonly known as laughing gas or nitrous, is a chemical compound, an oxide of nitrogen with the formula.
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Nonsteroidal anti-inflammatory drug
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation.
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Nucleoside
Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group.
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Omeprazole
Omeprazole, sold under the brand names Prilosec and Losec among others, is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome.
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Osteosarcoma
An osteosarcoma (OS) or osteogenic sarcoma (OGS) is a cancerous tumor in a bone.
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OxfordDictionaries.com
OxfordDictionaries.com, originally titled Oxford Dictionaries Online (ODO) and rebranded Oxford Living Dictionaries in 2017, is an online dictionary produced by the Oxford University Press (OUP) publishing house, a department of the University of Oxford, which also publishes a number of print dictionaries, among other works.
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Paracetamol
--> Acetanilide was the first aniline derivative serendipitously found to possess analgesic as well as antipyretic properties, and was quickly introduced into medical practice under the name of Antifebrin by A. Cahn and P. Hepp in 1886. But its unacceptable toxic effects, the most alarming being cyanosis due to methemoglobinemia, prompted the search for less toxic aniline derivatives. Harmon Northrop Morse had already synthesised paracetamol at Johns Hopkins University via the reduction of ''p''-nitrophenol with tin in glacial acetic acid in 1877, but it was not until 1887 that clinical pharmacologist Joseph von Mering tried paracetamol on humans. In 1893, von Mering published a paper reporting on the clinical results of paracetamol with phenacetin, another aniline derivative. Von Mering claimed that, unlike phenacetin, paracetamol had a slight tendency to produce methemoglobinemia. Paracetamol was then quickly discarded in favor of phenacetin. The sales of phenacetin established Bayer as a leading pharmaceutical company. Overshadowed in part by aspirin, introduced into medicine by Heinrich Dreser in 1899, phenacetin was popular for many decades, particularly in widely advertised over-the-counter "headache mixtures", usually containing phenacetin, an aminopyrine derivative of aspirin, caffeine, and sometimes a barbiturate. Paracetamol is the active metabolite of phenacetin and acetanilide, both once popular as analgesics and antipyretics in their own right. However, unlike phenacetin, acetanilide and their combinations, paracetamol is not considered carcinogenic at therapeutic doses. Von Mering's claims remained essentially unchallenged for half a century, until two teams of researchers from the United States analyzed the metabolism of acetanilide and paracetamol. In 1947 David Lester and Leon Greenberg found strong evidence that paracetamol was a major metabolite of acetanilide in human blood, and in a subsequent study they reported that large doses of paracetamol given to albino rats did not cause methemoglobinemia. In three papers published in the September 1948 issue of the Journal of Pharmacology and Experimental Therapeutics, Bernard Brodie, Julius Axelrod and Frederick Flinn confirmed using more specific methods that paracetamol was the major metabolite of acetanilide in human blood, and established that it was just as efficacious an analgesic as its precursor. They also suggested that methemoglobinemia is produced in humans mainly by another metabolite, phenylhydroxylamine. A follow-up paper by Brodie and Axelrod in 1949 established that phenacetin was also metabolised to paracetamol. This led to a "rediscovery" of paracetamol. It has been suggested that contamination of paracetamol with 4-aminophenol, the substance von Mering synthesised it from, may be the cause for his spurious findings. Paracetamol was first marketed in the United States in 1950 under the name Triagesic, a combination of paracetamol, aspirin, and caffeine. Reports in 1951 of three users stricken with the blood disease agranulocytosis led to its removal from the marketplace, and it took several years until it became clear that the disease was unconnected. Paracetamol was marketed in 1953 by Sterling-Winthrop Co. as Panadol, available only by prescription, and promoted as preferable to aspirin since it was safe for children and people with ulcers. In 1955, paracetamol was marketed as Children's Tylenol Elixir by McNeil Laboratories. In 1956, 500 mg tablets of paracetamol went on sale in the United Kingdom under the trade name Panadol, produced by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc. In 1963, paracetamol was added to the British Pharmacopoeia, and has gained popularity since then as an analgesic agent with few side-effects and little interaction with other pharmaceutical agents. Concerns about paracetamol's safety delayed its widespread acceptance until the 1970s, but in the 1980s paracetamol sales exceeded those of aspirin in many countries, including the United Kingdom. This was accompanied by the commercial demise of phenacetin, blamed as the cause of analgesic nephropathy and hematological toxicity. In 1988 Sterling Winthrop was acquired by Eastman Kodak which sold the over the counter drug rights to SmithKline Beecham in 1994. Available without a prescription since 1959, it has since become a common household drug. Patents on paracetamol have long expired, and generic versions of the drug are widely available.
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Paromomycin
Paromomycin is an antibiotic used to treat a number of infections including amebiasis, giardiasis, leishmaniasis, and tapeworm infection.
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Penicillin
Penicillin (PCN or pen) is a group of antibiotics which include penicillin G (intravenous use), penicillin V (use by mouth), procaine penicillin, and benzathine penicillin (intramuscular use).
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Pneumonitis
Pneumonitis or pulmonitis is an inflammation of lung tissue due to factors other than microorganisms.
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Post-chemotherapy cognitive impairment
Post-chemotherapy cognitive impairment (PCCI) (also known in the scientific community as "CRCIs or Chemotherapy-Related Cognitive Impairments" and in lay terms as chemotherapy-induced cognitive dysfunction or impairment, chemo brain, or chemo fog) describes the cognitive impairment that can result from chemotherapy treatment.
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Pregnancy category
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy.
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Probenecid
Probenecid, also sold under the brandname Probalan, is a medication that increases uric acid excretion in the urine.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Proton-pump inhibitor
Proton-pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of stomach acid production.
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Psoriasis
Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin.
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Psoriatic arthritis
Psoriatic arthritis is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis.
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Pulmonary fibrosis
Pulmonary fibrosis (literally "scarring of the lungs") is a respiratory disease in which scars are formed in the lung tissues, leading to serious breathing problems.
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Purine
A purine is a heterocyclic aromatic organic compound that consists of a pyrimidine ring fused to an imidazole ring.
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Purine metabolism
Purine metabolism refers to the metabolic pathways to synthesize and break down purines that are present in many organisms.
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Pyrimidine
Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine.
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Pyrimidone
Pyrimidone is the name given to either of two heterocyclic compounds with the formula C4H4N2O: 2-pyrimidone and 4-pyrimidone.
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Respiratory disease
Respiratory disease is a medical term that encompasses pathological conditions affecting the organs and tissues that make gas exchange possible in higher organisms, and includes conditions of the upper respiratory tract, trachea, bronchi, bronchioles, alveoli, pleura and pleural cavity, and the nerves and muscles of breathing.
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Retinoid
The retinoids are a class of chemical compounds that are vitamers of vitamin A or are chemically related to it.
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Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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Sarcoidosis
Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas.
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Sidney Farber
Sidney Farber (September 30, 1903 – March 30, 1973) was an American pediatric pathologist.
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Stomatitis
Stomatitis is inflammation of the mouth and lips.
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Stroke
A stroke is a medical condition in which poor blood flow to the brain results in cell death.
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Structural analog
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
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Subcutaneous injection
A subcutaneous injection is administered as a bolus into the subcutis, the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis.
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Systemic lupus erythematosus
Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.
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T cell
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
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Teratology
Teratology is the study of abnormalities of physiological development.
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Tetrahydrofolic acid
Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative.
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The Economist
The Economist is an English-language weekly magazine-format newspaper owned by the Economist Group and edited at offices in London.
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Therapeutic index
The therapeutic index (TI; also referred to as therapeutic ratio) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxicity.
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Thymidine
Thymidine (deoxythymidine; other names deoxyribosylthymine, thymine deoxyriboside) is a pyrimidine deoxynucleoside.
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Thymidine monophosphate
Thymidine monophosphate (TMP), also known as thymidylic acid (conjugate base thymidylate), deoxythymidine monophosphate (dTMP), or deoxythymidylic acid (conjugate base deoxythymidylate), is a nucleotide that is used as a monomer in DNA.
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TNF inhibitor
A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.
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Trimethoprim
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections.
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Trophoblastic neoplasm
Trophoblastic neoplasms are neoplasms which derive from trophoblastic tissue.
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Tumors of the hematopoietic and lymphoid tissues
Tumors of the hematopoietic and lymphoid tissues or haematopoietic and lymphoid malignancies are tumors that affect the blood, bone marrow, lymph, and lymphatic system.
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Ulcerative colitis
Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.
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Valproate
Valproate (VPA), and its valproic acid, sodium valproate, and valproate semisodium forms, are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches.
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Vasculitis
Vasculitis is a group of disorders that destroy blood vessels by inflammation.
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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Yellapragada Subbarow
Yellapragada Subbarao (12 January 1895 – 8 August 1948) was an Indian biochemist who discovered the function of adenosine triphosphate as an energy source in the cell, developed methotrexate for the treatment of cancer and discovered a broad spectrum antibiotic Auromycin and Tetracycline.
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Redirects here:
ATC code L01BA01, ATC code L04AX03, ATCvet code QL01BA01, ATCvet code QL04AX03, Abitrexate, Amethopterin, Antifolan, Arbitrexate, C20H22N8O5, Emtexate, Ledertrexate, Maxtrex, Metatrexan, Methatrixate, Methotrate, Methotrexat, Methotrexate sodium, Methotrixate, Methrotrexate, Methyltrexate, Metoart, Metoject, Mexate, Rheumatrex, Trexall.
References
[1] https://en.wikipedia.org/wiki/Methotrexate
