Get it on Google Play
New! Download Unionpedia on your Android™ device!
Faster access than browser!


Index Methylation

In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. [1]

102 relations: Alkoxide, Alkylation, Amine, Amino acid, Anisole, Arginine, Asymmetric dimethylarginine, Azaleatin, Biochemistry, Biological system, Biology, Bisulfite sequencing, Caffeoyl-CoA O-methyltransferase, Carbohydrate, Carbonyl group, Carboxylate, Catalysis, Chemistry, Cobalamin, CpG site, Cytosine, Demethylation, Diazomethane, Dimethyl carbonate, Dimethyl sulfate, Dimethylzinc, DNA methylation, DNA methyltransferase, Electrophile, Enol, Enzyme, Epigenetics, Eschweiler–Clarke reaction, Ester, Ether, Food chain, Gene expression, Grignard reaction, Guanine, Heavy metals, Histone, Histone methyltransferase, Homocysteine, Housekeeping gene, Ketone, Levomefolic acid, Lignin, Lysine, Menshutkin reaction, Messenger RNA, ..., Methanogenesis, MethDB, Methionine, Methionine synthase, Methoxy group, Methyl fluorosulfonate, Methyl group, Methyl iodide, Methyl trifluoromethanesulfonate, Methylarsonic acid, Methylation, Methyllithium, Methylmagnesium chloride, Methylmercury, MicroRNA, Microscale thermophoresis, Monolignol, N6-Methyladenosine, Nucleophile, Nucleophilic substitution, Nysted reagent, Organic chemistry, Organic Syntheses, Petasis reagent, Phenol, Phenols, Post-transcriptional modification, Post-translational modification, Precursor (chemistry), Promoter (genetics), Protein methylation, Residue (chemistry), Ribosomal RNA, S-Adenosyl methionine, Silver oxide, Small nuclear RNA, Small nucleolar RNA, Soil science, Substrate (chemistry), Tebbe's reagent, Tetrahydrofolic acid, Tetramethylammonium chloride, Tetramethyltin, Transfer RNA, Transfer-messenger RNA, Trimethylaluminium, Trimethylsilyldiazomethane, Wittig reaction, Zinc, 5-Methylcytosine, 5-O-Methylgenistein, 5-O-Methylmyricetin. Expand index (52 more) »


An alkoxide is the conjugate base of an alcohol and therefore consists of an organic group bonded to a negatively charged oxygen atom.

New!!: Methylation and Alkoxide · See more »


Alkylation is the transfer of an alkyl group from one molecule to another.

New!!: Methylation and Alkylation · See more »


In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.

New!!: Methylation and Amine · See more »

Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

New!!: Methylation and Amino acid · See more »


Anisole, or methoxybenzene, is an organic compound with the formula CH3OC6H5.

New!!: Methylation and Anisole · See more »


Arginine (symbol Arg or R) is an α-amino acid that is used in the biosynthesis of proteins.

New!!: Methylation and Arginine · See more »

Asymmetric dimethylarginine

Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma.

New!!: Methylation and Asymmetric dimethylarginine · See more »


Azaleatin is a chemical compound.

New!!: Methylation and Azaleatin · See more »


Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms.

New!!: Methylation and Biochemistry · See more »

Biological system

A biological system is a complex network of biologically relevant entities.

New!!: Methylation and Biological system · See more »


Biology is the natural science that studies life and living organisms, including their physical structure, chemical composition, function, development and evolution.

New!!: Methylation and Biology · See more »

Bisulfite sequencing

Bisulfite sequencing (also known as bisulphite sequencing) is the use of bisulfite treatment of DNA to determine its pattern of methylation.

New!!: Methylation and Bisulfite sequencing · See more »

Caffeoyl-CoA O-methyltransferase

In enzymology, a caffeoyl-CoA O-methyltransferase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are S-adenosyl methionine and caffeoyl-CoA, whereas its two products are S-adenosylhomocysteine and feruloyl-CoA.

New!!: Methylation and Caffeoyl-CoA O-methyltransferase · See more »


A carbohydrate is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water); in other words, with the empirical formula (where m may be different from n).

New!!: Methylation and Carbohydrate · See more »

Carbonyl group

In organic chemistry, a carbonyl group is a functional group composed of a carbon atom double-bonded to an oxygen atom: C.

New!!: Methylation and Carbonyl group · See more »


A carboxylate is a salt or ester of a carboxylic acid.

New!!: Methylation and Carboxylate · See more »


Catalysis is the increase in the rate of a chemical reaction due to the participation of an additional substance called a catalysthttp://goldbook.iupac.org/C00876.html, which is not consumed in the catalyzed reaction and can continue to act repeatedly.

New!!: Methylation and Catalysis · See more »


Chemistry is the scientific discipline involved with compounds composed of atoms, i.e. elements, and molecules, i.e. combinations of atoms: their composition, structure, properties, behavior and the changes they undergo during a reaction with other compounds.

New!!: Methylation and Chemistry · See more »


Cobalamin (Cbl) is a general term that is referred to a number of compounds, that have cobalt ion in the middle, hence the name of the compound.

New!!: Methylation and Cobalamin · See more »

CpG site

The CpG sites or CG sites are regions of DNA where a cytosine nucleotide is followed by a guanine nucleotide in the linear sequence of bases along its 5' → 3' direction.

New!!: Methylation and CpG site · See more »


Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

New!!: Methylation and Cytosine · See more »


Demethylation is the chemical process resulting in the removal of a methyl group (CH3) from a molecule.

New!!: Methylation and Demethylation · See more »


Diazomethane is the chemical compound CH2N2, discovered by German chemist Hans von Pechmann in 1894.

New!!: Methylation and Diazomethane · See more »

Dimethyl carbonate

Dimethyl carbonate (DMC) is an organic compound with the formula OC(OCH3)2.

New!!: Methylation and Dimethyl carbonate · See more »

Dimethyl sulfate

Dimethyl sulfate is a chemical compound with formula (CH3O)2SO2.

New!!: Methylation and Dimethyl sulfate · See more »


Dimethylzinc, also known as Zinc methyl, DMZ, or DMZn is a colorless volatile liquid Zn(CH3)2, formed by the action of methyl iodide on zinc at elevated temperature or on zinc sodium alloy.

New!!: Methylation and Dimethylzinc · See more »

DNA methylation

DNA methylation is a process by which methyl groups are added to the DNA molecule.

New!!: Methylation and DNA methylation · See more »

DNA methyltransferase

In biochemistry, the DNA methyltransferase (DNA MTase) family of enzymes catalyze the transfer of a methyl group to DNA.

New!!: Methylation and DNA methyltransferase · See more »


In organic chemistry, an electrophile is a reagent attracted to electrons.

New!!: Methylation and Electrophile · See more »


Enols, or more formally, alkenols, are a type of reactive structure or intermediate in organic chemistry that is represented as an alkene (olefin) with a hydroxyl group attached to one end of the alkene double bond.

New!!: Methylation and Enol · See more »


Enzymes are macromolecular biological catalysts.

New!!: Methylation and Enzyme · See more »


Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence.

New!!: Methylation and Epigenetics · See more »

Eschweiler–Clarke reaction

The Eschweiler–Clarke reaction (also called the Eschweiler–Clarke methylation) is a chemical reaction whereby a primary (or secondary) amine is methylated using excess formic acid and formaldehyde.

New!!: Methylation and Eschweiler–Clarke reaction · See more »


In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.

New!!: Methylation and Ester · See more »


Ethers are a class of organic compounds that contain an ether group—an oxygen atom connected to two alkyl or aryl groups.

New!!: Methylation and Ether · See more »

Food chain

A food chain is a linear network of links in a food web starting from producer organisms (such as grass or trees which use radiation from the Sun to make their food) and ending at apex predator species (like grizzly bears or killer whales), detritivores (like earthworms or woodlice), or decomposer species (such as fungi or bacteria).

New!!: Methylation and Food chain · See more »

Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

New!!: Methylation and Gene expression · See more »

Grignard reaction

The Grignard reaction (pronounced) is an organometallic chemical reaction in which alkyl, vinyl, or aryl-magnesium halides (Grignard reagents) add to a carbonyl group in an aldehyde or ketone.

New!!: Methylation and Grignard reaction · See more »


Guanine (or G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).

New!!: Methylation and Guanine · See more »

Heavy metals

Heavy metals are generally defined as metals with relatively high densities, atomic weights, or atomic numbers.

New!!: Methylation and Heavy metals · See more »


In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes.

New!!: Methylation and Histone · See more »

Histone methyltransferase

Histone methyltransferases (HMT) are histone-modifying enzymes (e.g., histone-lysine N-methyltransferases and histone-arginine N-methyltransferases), that catalyze the transfer of one, two, or three methyl groups to lysine and arginine residues of histone proteins.

New!!: Methylation and Histone methyltransferase · See more »


Homocysteine is a non-proteinogenic α-amino acid.

New!!: Methylation and Homocysteine · See more »

Housekeeping gene

In molecular biology, housekeeping genes are typically constitutive genes that are required for the maintenance of basic cellular function, and are expressed in all cells of an organism under normal and patho-physiological conditions.

New!!: Methylation and Housekeeping gene · See more »


In chemistry, a ketone (alkanone) is an organic compound with the structure RC(.

New!!: Methylation and Ketone · See more »

Levomefolic acid

Levomefolic acid (INN) (also known as L-5-MTHF, L-methylfolate and L-5-methyltetrahydrofolate and (6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine.

New!!: Methylation and Levomefolic acid · See more »


Lignin is a class of complex organic polymers that form important structural materials in the support tissues of vascular plants and some algae. Lignins are particularly important in the formation of cell walls, especially in wood and bark, because they lend rigidity and do not rot easily. Chemically, lignins are cross-linked phenolic polymers.

New!!: Methylation and Lignin · See more »


Lysine (symbol Lys or K) is an α-amino acid that is used in the biosynthesis of proteins.

New!!: Methylation and Lysine · See more »

Menshutkin reaction

In organic chemistry, the Menshutkin reaction converts a tertiary amine into a quaternary ammonium salt by reaction with an alkyl halide.

New!!: Methylation and Menshutkin reaction · See more »

Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

New!!: Methylation and Messenger RNA · See more »


Methanogenesis or biomethanation is the formation of methane by microbes known as methanogens.

New!!: Methylation and Methanogenesis · See more »


MethDB is a database for DNA methylation data.

New!!: Methylation and MethDB · See more »


Methionine (symbol Met or M) is an essential amino acid in humans.

New!!: Methylation and Methionine · See more »

Methionine synthase

Methionine synthase also known as MS, MeSe, MetH is responsible for the regeneration of methionine from homocysteine.

New!!: Methylation and Methionine synthase · See more »

Methoxy group

A methoxy group is the functional group consisting of a methyl group bound to oxygen.

New!!: Methylation and Methoxy group · See more »

Methyl fluorosulfonate

Methyl fluorosulfonate, also known as magic methyl, is the organic compound with the formula FSO2OCH3.

New!!: Methylation and Methyl fluorosulfonate · See more »

Methyl group

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.

New!!: Methylation and Methyl group · See more »

Methyl iodide

Methyl iodide, also called iodomethane, and commonly abbreviated "MeI", is the chemical compound with the formula CH3I.

New!!: Methylation and Methyl iodide · See more »

Methyl trifluoromethanesulfonate

Methyl trifluoromethanesulfonate, also commonly called methyl triflate and abbreviated MeOTf, is the organic compound with the formula CF3SO2OCH3.

New!!: Methylation and Methyl trifluoromethanesulfonate · See more »

Methylarsonic acid

Methylarsonic acid is an organoarsenic compound with the formula CH3AsO3H2.

New!!: Methylation and Methylarsonic acid · See more »


In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.

New!!: Methylation and Methylation · See more »


Methyllithium is the simplest organolithium reagent with the empirical formula CH3Li.

New!!: Methylation and Methyllithium · See more »

Methylmagnesium chloride

Methylmagnesium chloride is an organometallic compound with the general formula CH3MgCl.

New!!: Methylation and Methylmagnesium chloride · See more »


Methylmercury (sometimes methyl mercury) is an organometallic cation with the formula.

New!!: Methylation and Methylmercury · See more »


A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.

New!!: Methylation and MicroRNA · See more »

Microscale thermophoresis

Microscale thermophoresis (MST) is a technology for the interaction analysis of biomolecules.

New!!: Methylation and Microscale thermophoresis · See more »


Monolignols are phytochemicals acting as source materials for biosynthesis of both lignans and lignin.

New!!: Methylation and Monolignol · See more »


N6-Methyladenosine (m6A) is an abundant modification in mRNA and is found within some viruses, and most eukaryotes including mammals, insects, plants and yeast.

New!!: Methylation and N6-Methyladenosine · See more »


Nucleophile is a chemical species that donates an electron pair to an electrophile to form a chemical bond in relation to a reaction.

New!!: Methylation and Nucleophile · See more »

Nucleophilic substitution

In organic and inorganic chemistry, nucleophilic substitution is a fundamental class of reactions in which an electron rich nucleophile selectively bonds with or attacks the positive or partially positive charge of an atom or a group of atoms to replace a leaving group; the positive or partially positive atom is referred to as an electrophile.

New!!: Methylation and Nucleophilic substitution · See more »

Nysted reagent

The Nysted reagent is a reagent used in organic synthesis for the methenylation of a carbonyl group.

New!!: Methylation and Nysted reagent · See more »

Organic chemistry

Organic chemistry is a chemistry subdiscipline involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.

New!!: Methylation and Organic chemistry · See more »

Organic Syntheses

Organic Syntheses is a peer-reviewed scientific journal that was established in 1921.

New!!: Methylation and Organic Syntheses · See more »

Petasis reagent

The Petasis reagent is an organotitanium compound with the formula Cp2Ti(CH3)2.

New!!: Methylation and Petasis reagent · See more »


Phenol, also known as phenolic acid, is an aromatic organic compound with the molecular formula C6H5OH.

New!!: Methylation and Phenol · See more »


In organic chemistry, phenols, sometimes called phenolics, are a class of chemical compounds consisting of a hydroxyl group (—OH) bonded directly to an aromatic hydrocarbon group.

New!!: Methylation and Phenols · See more »

Post-transcriptional modification

Post-transcriptional modification or Co-transcriptional modification is the process in eukaryotic cells where primary transcript RNA is converted into mature RNA.

New!!: Methylation and Post-transcriptional modification · See more »

Post-translational modification

Post-translational modification (PTM) refers to the covalent and generally enzymatic modification of proteins following protein biosynthesis.

New!!: Methylation and Post-translational modification · See more »

Precursor (chemistry)

In chemistry, a precursor is a compound that participates in a chemical reaction that produces another compound.

New!!: Methylation and Precursor (chemistry) · See more »

Promoter (genetics)

In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.

New!!: Methylation and Promoter (genetics) · See more »

Protein methylation

Protein methylation is the process through which a group of specific enzymes, the methyltransferases modify proteins by adding a methyl groups.

New!!: Methylation and Protein methylation · See more »

Residue (chemistry)

In chemistry residue is whatever remains or acts as a contaminant after a given class of events.

New!!: Methylation and Residue (chemistry) · See more »

Ribosomal RNA

Ribosomal ribonucleic acid (rRNA) is the RNA component of the ribosome, and is essential for protein synthesis in all living organisms.

New!!: Methylation and Ribosomal RNA · See more »

S-Adenosyl methionine

S-Adenosyl methionineSAM-e, SAMe, SAM, S-Adenosyl-L-methionine, AdoMet, ademetionine is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation.

New!!: Methylation and S-Adenosyl methionine · See more »

Silver oxide

Silver(I) oxide is the chemical compound with the formula Ag2O.

New!!: Methylation and Silver oxide · See more »

Small nuclear RNA

Small nuclear ribonucleic acid (snRNA), also commonly referred to as U-RNA, is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic cells.

New!!: Methylation and Small nuclear RNA · See more »

Small nucleolar RNA

Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs.

New!!: Methylation and Small nucleolar RNA · See more »

Soil science

Soil science is the study of soil as a natural resource on the surface of the Earth including soil formation, classification and mapping; physical, chemical, biological, and fertility properties of soils; and these properties in relation to the use and management of soils.

New!!: Methylation and Soil science · See more »

Substrate (chemistry)

In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.

New!!: Methylation and Substrate (chemistry) · See more »

Tebbe's reagent

The Tebbe reagent is the organometallic compound with the formula (C5H5)2TiCH2ClAl(CH3)2.

New!!: Methylation and Tebbe's reagent · See more »

Tetrahydrofolic acid

Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative.

New!!: Methylation and Tetrahydrofolic acid · See more »

Tetramethylammonium chloride

Tetramethylammonium chloride is one of the simplest quaternary ammonium salts, with four methyl groups tetrahedrally attached to the central N. The chemical formula (CH3)4N+Cl− is often abbreviated further as Me4N+Cl−.

New!!: Methylation and Tetramethylammonium chloride · See more »


Tetramethyltin is an organometallic compound with the formula (CH3)4Sn.

New!!: Methylation and Tetramethyltin · See more »

Transfer RNA

A transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length, that serves as the physical link between the mRNA and the amino acid sequence of proteins.

New!!: Methylation and Transfer RNA · See more »

Transfer-messenger RNA

Transfer-messenger RNA (abbreviated tmRNA, also known as 10Sa RNA and by its genetic name SsrA) is a bacterial RNA molecule with dual tRNA-like and messenger RNA-like properties.

New!!: Methylation and Transfer-messenger RNA · See more »


Trimethylaluminium is one of the simplest examples of an organoaluminium compound.

New!!: Methylation and Trimethylaluminium · See more »


Trimethylsilyldiazomethane is the organosilicon compound with the formula (CH3)3SiCHN2.

New!!: Methylation and Trimethylsilyldiazomethane · See more »

Wittig reaction

The Wittig reaction or Wittig olefination is a chemical reaction of an aldehyde or ketone with a triphenyl phosphonium ylide (often called a Wittig reagent) to give an alkene and triphenylphosphine oxide.

New!!: Methylation and Wittig reaction · See more »


Zinc is a chemical element with symbol Zn and atomic number 30.

New!!: Methylation and Zinc · See more »


5-Methylcytosine is a methylated form of the DNA base cytosine that may be involved in the regulation of gene transcription.

New!!: Methylation and 5-Methylcytosine · See more »


5-O-Methylgenistein is an O-methylated isoflavone.

New!!: Methylation and 5-O-Methylgenistein · See more »


5-O-Methylmyricetin is an O-methylated flavonol, a type of flavonoid.

New!!: Methylation and 5-O-Methylmyricetin · See more »

Redirects here:

5-O-Methyl, 5-O-Methylation, Biomethylation, Epigenetic methylation, Hypermethylated, Hypermethylation, Irvine-Purdie methylation, Irvine–Purdie methylation, Methylate, Methylated, Methylates, Methylating, Methylating agent, Methylation capacity, Purdie methylation, RNA methylation.


[1] https://en.wikipedia.org/wiki/Methylation

Hey! We are on Facebook now! »