Metitepine

Metitepine (developmental code names Ro 8-6837 (maleate), VUFB-6276 (mesylate)), also known as methiothepin, is a drug described as a "psychotropic agent" of the tricyclic group which was never marketed. ^[1]

Adrenergic receptor

The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β2) agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example.

See Metitepine and Adrenergic receptor

Antipsychotic

Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders. Metitepine and Antipsychotic are antipsychotics and Dopamine antagonists.

See Metitepine and Antipsychotic

Binding selectivity

In chemistry, binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

See Metitepine and Binding selectivity

Clorotepine

Clorotepine (brand names Clotepin, Clopiben), also known as octoclothepin or octoclothepine, is an antipsychotic of the tricyclic group which was derived from perathiepin in 1965 and marketed in the Czech Republic by Spofa in or around 1971 for the treatment of schizophrenic psychosis. Metitepine and Clorotepine are antipsychotics, Dibenzothiepines and Diphenylethylpiperazines.

See Metitepine and Clorotepine

Dopamine receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS).

See Metitepine and Dopamine receptor

Drug

A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect.

See Metitepine and Drug

Maleic acid

Maleic acid or cis-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups.

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Mesylate

In organosulfur chemistry, a mesylate is any salt or ester of methanesulfonic acid.

See Metitepine and Mesylate

Perathiepin

Perathiepin is a neuroleptic drug of the tricyclic family which was developed in the 1960s but was never marketed. Metitepine and Perathiepin are antipsychotics, Dibenzothiepines and Diphenylethylpiperazines.

See Metitepine and Perathiepin

Psychoactive drug

A psychoactive drug, mind-altering drug, or consciousness-altering drug is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.

See Metitepine and Psychoactive drug

Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

See Metitepine and Receptor antagonist

Tricyclic

Tricyclics are cyclic chemical compounds that contain three fused rings of atoms.

See Metitepine and Tricyclic

5-HT receptor

5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.

See Metitepine and 5-HT receptor

References

[1] https://en.wikipedia.org/wiki/Metitepine

Also known as C20H24N2S2, Methiothepin, Methiothepine.

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Metitepine

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