56 relations: Agonist, Aldosterone, Anabolic steroid, Anabolism, Androgen, Androgen receptor, Antiandrogen, Antimineralocorticoid, Bodybuilding, Breast cancer, Dehydrogenation, Derivative (chemistry), Dihydrotestosterone, Dimethyltrienolone, Doping in sport, Drug metabolism, Estradiol (medication), Estrane, Glucocorticoid receptor, Hepatotoxicity, HSD3B1, HSD3B2, IC50, Ligand (biochemistry), Ligand binding assay, Medicine, Metastatic breast cancer, Methyl group, Methyltestosterone, Mibolerone, Mineralocorticoid receptor, Nandrolone, Normethandrone, Oral administration, Organic compound, Pharmacodynamics, Photoaffinity labeling, Potency (pharmacology), Progesterone (medication), Progesterone receptor, Progestogen, Scientific method, Sex hormone-binding globulin, Side effect, Spironolactone, Steroid, Structural analog, Testosterone (medication), Trademark distinctiveness, Trenbolone, ..., Trestolone, Trimethyltrienolone, Virilization, 17α-Alkylated anabolic steroid, 2008 Summer Olympics, 3β-Hydroxysteroid dehydrogenase. Expand index (6 more) » « Shrink index
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
Anabolism (from ἁνά, "upward" and βάλλειν, "to throw") is the set of metabolic pathways that construct molecules from smaller units.
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body.
An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.
Bodybuilding is the use of progressive resistance exercise to control and develop one's musculature.
Breast cancer is cancer that develops from breast tissue.
Christmas is an annual festival commemorating the birth of Jesus Christ,Martindale, Cyril Charles.
The Christmas season, also called the festive season, or the holiday season (mainly in the U.S. and Canada; often simply called the holidays),, is an annually recurring period recognized in many Western and Western-influenced countries that is generally considered to run from late November to early January.
Christmas Eve is the evening or entire day before Christmas Day, the festival commemorating the birth of Jesus.
Christmas traditions vary from country to country.
Dehydrogenation is a chemical reaction that involves the removal of hydrogen from an organic molecule.
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.
Dimethyltrienolone (developmental code name RU-2420) is a synthetic, orally active, and extremely potent anabolic–androgenic steroid (AAS) and 17α-alkylated 19-nortestosterone (nandrolone) derivative which was never marketed for medical use.
In competitive sports, doping is the use of banned athletic performance-enhancing drugs by athletic competitors.
Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems.
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
Estrane is a C18 steroid derivative, with a gonane core.
The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.
HSD3B1 is a human gene that encodes for a 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type I or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1.
HSD3B2 is a human gene that encodes for 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type II or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2.
The half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
Ligand binding assays (LBA) is an assay, or an analytic procedure, whose procedure or method relies on the binding of ligand molecules to receptors, antibodies or other macromolecules.
Medicine is the science and practice of the diagnosis, treatment, and prevention of disease.
Metastatic breast cancer, also referred to as metastases, advanced breast cancer, secondary tumours, secondaries or stage 4 breast cancer, is a stage of breast cancer where the disease has spread to distant sites beyond the axillary lymph nodes.
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.
Methyltestosterone, sold under the brand names Android, Metandren, and Testred among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women.
Mibolerone, also known as dimethylnortestosterone (DMNT) and sold under the brand names Cheque Drops and Matenon, is a synthetic, orally active, and extremely potent anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was marketed by Upjohn for use as a veterinary drug.
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2.
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).
New Year is the time or day at which a new calendar year begins and the calendar's year count increments by one.
New Year's Day, also called simply New Year's or New Year, is observed on January 1, the first day of the year on the modern Gregorian calendar as well as the Julian calendar.
In the Gregorian calendar, New Year's Eve (also known as Old Year's Day or Saint Sylvester's Day in many countries), the last day of the year, is on 31 December which is the seventh day of Christmastide.
Normethandrone, also known as methylestrenolone or methylnortestosterone and sold under the brand name Metalutin among others, is a progestin and androgen/anabolic steroid (AAS) medication which is used in combination with an estrogen in the treatment of amenorrhea and menopausal symptoms in women.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).
Photoaffinity labeling is a technique used to attach "labels" to the active site of a large molecule, especially a protein.
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
Progesterone is a medication and naturally occurring steroid hormone.
The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
Scientific method is an empirical method of knowledge acquisition, which has characterized the development of natural science since at least the 17th century, involving careful observation, which includes rigorous skepticism about what one observes, given that cognitive assumptions about how the world works influence how one interprets a percept; formulating hypotheses, via induction, based on such observations; experimental testing and measurement of deductions drawn from the hypotheses; and refinement (or elimination) of the hypotheses based on the experimental findings.
Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the two sex hormones: androgen and estrogen.
In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.
Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
Testosterone is a medication and naturally occurring steroid hormone.
Trademark distinctiveness is an important concept in the law governing trademarks and service marks.
Trenbolone is an androgen and anabolic steroid (AAS) of the nandrolone group which itself was never marketed.
Trestolone, also known as 7α-methyl-19-nortestosterone (MENT), is an experimental androgen/anabolic steroid (AAS) and progestogen medication which has been under development for potential use as a form of hormonal birth control for men and in androgen replacement therapy for low testosterone levels in men but has never been marketed for medical use.
Trimethyltrienolone (TMT), also known by its developmental code name R-2956 or RU-2956, is an antiandrogen medication which was never introduced for medical use but has been used in scientific research.
Virilization or masculinization is the biological development of sex differences, changes that make a male body different from a female body.
A 17α-alkylated anabolic steroid is a synthetic anabolic–androgenic steroid (AAS) that features an alkyl group, specifically a methyl or ethyl group, at the C17α position.
The 2008 Summer Olympic Games, officially known as the Games of the XXIX Olympiad and commonly known as Beijing 2008, was an international multi-sport event that was held from 8 to 24 August 2008 in Beijing, China.
2018 has been designated as the third International Year of the Reef by the International Coral Reef Initiative.
2019 (MMXIX) will be a common year starting on Tuesday of the Gregorian calendar, the 2019th year of the Common Era (CE) and Anno Domini (AD) designations, the 19th year of the 3rd millennium, the 19th year of the 21st century, and the 10th and last year of the 2010s decade.
3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) is an enzyme that catalyzes the biosynthesis of progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.
17α-Methyltrenbolone, 17α-Methyltrienolone, 17α-methyltrenbolone, 17α-methyltrienolone, Methyl-trenbolone, Methyl-trienolone, Methyltrenbolone, Methyltrienolone, NSC 92,858, NSC 92858, NSC-92,858, NSC-92858, NSC92,858, NSC92858, R 1881, R-1881, R1881, RU 1881, RU-1881, RU1881.