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Microsome

Index Microsome

In cell biology, microsomes are heterogeneous vesicle-like artifacts (~20-200 nm diameter) re-formed from pieces of the endoplasmic reticulum (ER) when eukaryotic cells are broken-up in the laboratory; microsomes are not present in healthy, living cells. [1]

Table of Contents

  1. 42 relations: Amino acid, Apolipoprotein B, Cell biology, Cell disruption, Cell nucleus, Cell-free protein synthesis, Centrifugation, Cytochrome P450, David D. Sabatini, Differential centrifugation, Drug metabolism, Endoplasmic reticulum, Escherichia coli, Eukaryote, Günter Blobel, Heme, Hepatocyte, Heterologous expression, Homeostasis, In vitro, Laboratory, Lipid, Lipoprotein, List of biological development disorders, Metabolic disorder, Metabolism, Metabolite, Metabolomics, Microsomal triglyceride transfer protein, Mitochondrion, Peptide, Precipitation (chemistry), Protease, Protein biosynthesis, Pulse-chase analysis, Ribosome, S9 fraction, Secretory protein, Sf9 (cells), Signal peptidase, Sphingolipid, Vesicle (biology and chemistry).

Amino acid

Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.

See Microsome and Amino acid

Apolipoprotein B

Apolipoprotein B (ApoB) is a protein that in humans is encoded by the gene.

See Microsome and Apolipoprotein B

Cell biology

Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells.

See Microsome and Cell biology

Cell disruption

Cell disruption is a method or process for releasing biological molecules from inside a cell.

See Microsome and Cell disruption

Cell nucleus

The cell nucleus (nuclei) is a membrane-bound organelle found in eukaryotic cells.

See Microsome and Cell nucleus

Cell-free protein synthesis

Cell-free protein synthesis, also known as in vitro protein synthesis or CFPS, is the production of protein using biological machinery in a cell-free system, that is, without the use of living cells.

See Microsome and Cell-free protein synthesis

Centrifugation

Centrifugation is a mechanical process which involves the use of the centrifugal force to separate particles from a solution according to their size, shape, density, medium viscosity and rotor speed.

See Microsome and Centrifugation

Cytochrome P450

Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases.

See Microsome and Cytochrome P450

David D. Sabatini

David Domingo Sabatini is an Argentine-American cell biologist and the Frederick L. Ehrman Professor Emeritus of Cell Biology in the Department of Cell Biology at New York University School of Medicine, which he chaired from 1972 to 2011.

See Microsome and David D. Sabatini

Differential centrifugation

In biochemistry and cell biology, differential centrifugation (also known as differential velocity centrifugation) is a common procedure used to separate organelles and other sub-cellular particles based on their sedimentation rate.

See Microsome and Differential centrifugation

Drug metabolism

Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems.

See Microsome and Drug metabolism

Endoplasmic reticulum

The endoplasmic reticulum (ER) is a part of a transportation system of the eukaryotic cell, and has many other important functions such as protein folding. Microsome and endoplasmic reticulum are membrane biology.

See Microsome and Endoplasmic reticulum

Escherichia coli

Escherichia coliWells, J. C. (2000) Longman Pronunciation Dictionary.

See Microsome and Escherichia coli

Eukaryote

The eukaryotes constitute the domain of Eukarya or Eukaryota, organisms whose cells have a membrane-bound nucleus.

See Microsome and Eukaryote

Günter Blobel

Günter Blobel (May 21, 1936 – February 18, 2018) was a Silesian German and American biologist and 1999 Nobel Prize laureate in Physiology for the discovery that proteins have intrinsic signals that govern their transport and localization in the cell.

See Microsome and Günter Blobel

Heme

Heme (American English), or haem (Commonwealth English, both pronounced /hi:m/), is a ring-shaped iron-containing molecular component of hemoglobin, which is necessary to bind oxygen in the bloodstream.

See Microsome and Heme

Hepatocyte

A hepatocyte is a cell of the main parenchymal tissue of the liver.

See Microsome and Hepatocyte

Heterologous expression

Heterologous expression refers to the expression of a gene or part of a gene in a host organism that does not naturally have the gene or gene fragment in question.

See Microsome and Heterologous expression

Homeostasis

In biology, homeostasis (British also homoeostasis) is the state of steady internal physical and chemical conditions maintained by living systems.

See Microsome and Homeostasis

In vitro

In vitro (meaning in glass, or in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

See Microsome and In vitro

Laboratory

A laboratory (colloquially lab) is a facility that provides controlled conditions in which scientific or technological research, experiments, and measurement may be performed.

See Microsome and Laboratory

Lipid

Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others.

See Microsome and Lipid

Lipoprotein

A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid (also known as fat) molecules in water, as in blood plasma or other extracellular fluids.

See Microsome and Lipoprotein

List of biological development disorders

The following is a list of terms used to describe biological disorders of development, arranged by root word and shared prefix.

See Microsome and List of biological development disorders

Metabolic disorder

A metabolic disorder is a disorder that negatively alters the body's processing and distribution of macronutrients, such as proteins, fats, and carbohydrates.

See Microsome and Metabolic disorder

Metabolism

Metabolism (from μεταβολή metabolÄ“, "change") is the set of life-sustaining chemical reactions in organisms.

See Microsome and Metabolism

Metabolite

In biochemistry, a metabolite is an intermediate or end product of metabolism.

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Metabolomics

Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism.

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Microsomal triglyceride transfer protein

Microsomal triglyceride transfer protein large subunit is a protein that in humans is encoded by the MTTP, also known as MTP, gene.

See Microsome and Microsomal triglyceride transfer protein

Mitochondrion

A mitochondrion is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi.

See Microsome and Mitochondrion

Peptide

Peptides are short chains of amino acids linked by peptide bonds.

See Microsome and Peptide

Precipitation (chemistry)

In an aqueous solution, precipitation is the "sedimentation of a solid material (a precipitate) from a liquid solution".

See Microsome and Precipitation (chemistry)

Protease

A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides or single amino acids, and spurring the formation of new protein products.

See Microsome and Protease

Protein biosynthesis

Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation or export) through the production of new proteins.

See Microsome and Protein biosynthesis

Pulse-chase analysis

In biochemistry and molecular biology, a pulse-chase analysis is a method for examining a cellular process occurring over time by successively exposing the cells to a labeled compound (pulse) and then to the same compound in an unlabeled form (chase).

See Microsome and Pulse-chase analysis

Ribosome

Ribosomes are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA translation).

See Microsome and Ribosome

S9 fraction

The S9 fraction is the product of an organ tissue homogenate used in biological assays.

See Microsome and S9 fraction

Secretory protein

A secretory protein is any protein, whether it be endocrine or exocrine, which is secreted by a cell.

See Microsome and Secretory protein

Sf9 (cells)

Sf9 cells, a clonal isolate of Spodoptera frugiperda Sf21 cells (IPLB-Sf21-AE), are commonly used in insect cell culture for recombinant protein production using baculovirus.

See Microsome and Sf9 (cells)

Signal peptidase

Signal peptidases are enzymes that convert secretory and some membrane proteins to their mature or pro forms by cleaving their signal peptides from their N-termini.

See Microsome and Signal peptidase

Sphingolipid

Sphingolipids are a class of lipids containing a backbone of sphingoid bases, which are a set of aliphatic amino alcohols that includes sphingosine.

See Microsome and Sphingolipid

Vesicle (biology and chemistry)

In cell biology, a vesicle is a structure within or outside a cell, consisting of liquid or cytoplasm enclosed by a lipid bilayer. Microsome and vesicle (biology and chemistry) are membrane biology.

See Microsome and Vesicle (biology and chemistry)

References

[1] https://en.wikipedia.org/wiki/Microsome

Also known as Microsomal, Microsomes.