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50 relations: Abdominal aortic aneurysm, Active site, Adenosine, Allele, Atherosclerosis, Basal lamina, Blood–brain barrier, Chelation, Claudin, Cleft lip and cleft palate, Collagen, Coordination complex, Cytokine, Elastin, Enzyme, Extracellular matrix, Fibronectin, Gene, Growth factor, Hemopexin, Hydrogen bond, Inflammation, Knockout mouse, Laminin, Matrix metalloproteinase, MEROPS, Metastasis, MMP1, MMP7, MMP9, Myocardial infarction, Neutrophil, Nucleophile, Occludin, Oncogene, Polymorphism (biology), Promoter (genetics), Protein precursor, Proteoglycan, Proteolysis, Scissile bond, Spinal cord, Spinal cord injury, Thermolysin, Tight junction, Tight junction protein 1, Tissue inhibitor of metalloproteinase, Traumatic brain injury, Wild type, Zymogen.
Abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA or triple A) is a localized enlargement of the abdominal aorta such that the diameter is greater than 3 cm or more than 50% larger than normal diameter.
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Active site
In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction.
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Adenosine
Adenosine is both a chemical found in many living systems and a medication.
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Allele
An allele is a variant form of a given gene.
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Atherosclerosis
Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.
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Basal lamina
The basal lamina is a layer of extracellular matrix secreted by the epithelial cells, on which the epithelium sits.
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Blood–brain barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).
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Chelation
Chelation is a type of bonding of ions and molecules to metal ions.
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Claudin
Claudins are a family of proteins which, along with occludin, are the most important components of the tight junctions) (zonulae occludentes). Tight junctions establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm.
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Cleft lip and cleft palate
Cleft lip and cleft palate, also known as orofacial cleft, is a group of conditions that includes cleft lip (CL), cleft palate (CP), and both together (CLP).
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Collagen
Collagen is the main structural protein in the extracellular space in the various connective tissues in animal bodies.
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Coordination complex
In chemistry, a coordination complex consists of a central atom or ion, which is usually metallic and is called the coordination centre, and a surrounding array of bound molecules or ions, that are in turn known as ligands or complexing agents.
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Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
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Elastin
Elastin is a highly elastic protein in connective tissue and allows many tissues in the body to resume their shape after stretching or contracting.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by support cells that provides structural and biochemical support to the surrounding cells.
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Fibronectin
Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Growth factor
A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.
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Hemopexin
Hemopexin (or haemopexin; Hpx; Hx), also known as beta-1B-glycoprotein, is a glycoprotein that in humans is encoded by the HPX gene and belongs to hemopexin family of proteins.
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Hydrogen bond
A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.
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Inflammation
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.
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Knockout mouse
A knockout mouse or knock-out mouse is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.
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Laminin
Laminins are high-molecular weight (~400 to ~900 kDa) proteins of the extracellular matrix.
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Matrix metalloproteinase
Matrix metalloproteinases (MMPs), also known as matrixins, are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins.
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MEROPS
MEROPS is an on-line database for peptidases (also known as proteases, proteinases and proteolytic enzymes) and their inhibitors.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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MMP1
Matrix metalloproteinase-1 (MMP-1) also known as interstitial collagenase and fibroblast collagenase is an enzyme that in humans is encoded by the MMP1 gene.
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MMP7
Matrilysin also known as matrix metalloproteinase-7 (MMP-7), pump-1 protease (PUMP-1), or uterine metalloproteinase is an enzyme in humans that is encoded by the MMP7 gene.
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MMP9
Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is a matrixin, a class of enzymes that belong to the zinc-metalloproteinases family involved in the degradation of the extracellular matrix.
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Myocardial infarction
Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.
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Neutrophil
Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.
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Nucleophile
Nucleophile is a chemical species that donates an electron pair to an electrophile to form a chemical bond in relation to a reaction.
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Occludin
Occludin is a protein that in humans is encoded by the OCLN gene.
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Oncogene
An oncogene is a gene that has the potential to cause cancer.
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Polymorphism (biology)
Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.
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Promoter (genetics)
In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.
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Protein precursor
A protein precursor, also called a pro-protein or pro-peptide, is an inactive protein (or peptide) that can be turned into an active form by post-translational modification, such as breaking off a piece of the molecule or adding on another molecule.
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Proteoglycan
Proteoglycans are proteins that are heavily glycosylated.
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Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.
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Scissile bond
In molecular biology, a scissile bond is a covalent chemical bond that can be broken by an enzyme.
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Spinal cord
The spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column.
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Spinal cord injury
A spinal cord injury (SCI) is damage to the spinal cord that causes temporary or permanent changes in its function.
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Thermolysin
Thermolysin (Bacillus thermoproteolyticus neutral proteinase, thermoase, thermoase Y10, TLN) is a thermostable neutral metalloproteinase enzyme produced by the Gram-positive bacteria Bacillus thermoproteolyticus.
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Tight junction
Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens) are multiprotein junctional complex whose general function is to prevent leakage of transported solutes and water and seals the paracellular pathway.
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Tight junction protein 1
Zonula occludens-1 ZO-1, also known as Tight junction protein-1 is a 220-kD peripheral membrane protein that is encoded by the TJP1 gene in humans.
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Tissue inhibitor of metalloproteinase
The matrix metalloproteinases are inhibited by specific endogenous tissue inhibitors of metalloproteinases (TIMPs), which comprise a family of four protease inhibitors: TIMP1, TIMP2, TIMP3 and TIMP4.
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Traumatic brain injury
Traumatic brain injury (TBI), also known as intracranial injury, occurs when an external force injures the brain.
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Wild type
Wild type (WT) refers to the phenotype of the typical form of a species as it occurs in nature.
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Zymogen
A zymogen, also called a proenzyme, is an inactive precursor of an enzyme.
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Redirects here:
MMP-3, MMP3 (gene), Matrix metallopeptidase 3, Mmp-3, STMY, STMY1, Stmy, Stmy1.
References
[1] https://en.wikipedia.org/wiki/MMP3
