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10 relations: Acyl-CoA:lysocardiolipin acyltransferase-1, Cardiolipin, Fatty acid, Inner mitochondrial membrane, Lipid, Lipid metabolism, Mitochondrion, Monolysocardiolipin acyltransferase, Phospholipid, Tafazzin.
Acyl-CoA:lysocardiolipin acyltransferase-1
Acyl-CoA:lysocardiolipin acyltransferase-1 (ALCAT1) is a polyglycerophospholipid acyltransferase of the endoplasmic reticulum which is primarily known for catalyzing the acylation of monolysocardiolipin back into cardiolipin, although it does catalyze the acylation of other polyglycerophospholipids.
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Cardiolipin
Cardiolipin (IUPAC name "1,3-bis(sn-3’-phosphatidyl)-sn-glycerol") is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition.
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Fatty acid
In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with a long aliphatic chain, which is either saturated or unsaturated.
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Inner mitochondrial membrane
The inner mitochondrial membrane (IMM) is the mitochondrial membrane which separates the mitochondrial matrix from the intermembrane space.
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Lipid
In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.
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Lipid metabolism
Lipid metabolism is the synthesis and degradation of lipids in cells, involving the break down or storage of fats for energy.
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Mitochondrion
The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.
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Monolysocardiolipin acyltransferase
Monolysocardiolipin acyltransferase (MLCL AT-1) is a mitochondrial acyltransferase that facilitates the remodeling of monolysocardiolipin (MLCL) into cardiolipin.
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Phospholipid
Phospholipids are a class of lipids that are a major component of all cell membranes.
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Tafazzin
Tafazzin is a protein that in humans is encoded by the TAZ gene.
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