13 relations: Agonist, Antagonist, Gastritis, Gastroesophageal reflux disease, HERG, Indigestion, Irritable bowel syndrome, Malaise, Neurogenesis, Prokinetic agent, Stomach, 5-HT3 receptor, 5-HT4 receptor.
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
An antagonist is a character, group of characters, institution or concept that stands in or represents opposition against which the protagonist(s) must contend.
Gastritis is inflammation of the lining of the stomach.
Gastroesophageal reflux disease (GERD), also known as acid reflux, is a long-term condition where stomach contents come back up into the esophagus resulting in either symptoms or complications.
hERG (the human Ether-à-go-go-Related Gene) is a gene that codes for a protein known as Kv11.1, the alpha subunit of a potassium ion channel.
Indigestion, also known as dyspepsia, is a condition of impaired digestion.
Irritable bowel syndrome (IBS) is a group of symptoms—including abdominal pain and changes in the pattern of bowel movements without any evidence of underlying damage.
Malaise is a feeling of general discomfort, uneasiness or pain, often the first indication of an infection or other disease.
Neurogenesis is the process by which nervous system cells, known as neurons, are produced by neural stem cells (NSC)s, and it occurs in all species of animals except the porifera (sponges) and placozoans.
A gastroprokinetic agent, gastrokinetic, or prokinetic, is a type of drug which enhances gastrointestinal motility by increasing the frequency of contractions in the small intestine or making them stronger, but without disrupting their rhythm.
The stomach (from ancient Greek στόμαχος, stomachos, stoma means mouth) is a muscular, hollow organ in the gastrointestinal tract of humans and many other animals, including several invertebrates.
The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin) receptors which are G protein-coupled receptors.
5-Hydroxytryptamine receptor 4 is a protein that in humans is encoded by the HTR4 gene.