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Mouse mammary tumor virus

Index Mouse mammary tumor virus

Mouse mammary tumor virus (MMTV) is a milk-transmitted retrovirus like the HTL viruses, HI viruses, and BLV. [1]

36 relations: Androgen, B cell, Betaretrovirus, Bovine leukemia virus, Estrogen, Glucocorticoid, HIV, Hormone, Hormone response element, Human T-lymphotropic virus, Jackson Laboratory, John Joseph Bittner, Journal of Virology, Long terminal repeat, Lymphocyte, Macrophage, Messenger RNA, Mouse models of breast cancer metastasis, Murinae, Nature (journal), Oncogene, Orthoretrovirinae, Peyer's patch, Polyomaviridae, Progestin, Prolactin, Provirus, Retrovirus, Rev (HIV), Reverse transcriptase, Steroid, Superantigen, T cell, T-cell receptor, Time (magazine), Vertically transmitted infection.

Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

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B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.

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Betaretrovirus

Betaretrovirus is a genus of the Retroviridae family.

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Bovine leukemia virus

Bovine leukemia virus (BLV) is a retrovirus which causes enzootic bovine leukosis in cattle.

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Estrogen

Estrogen, or oestrogen, is the primary female sex hormone.

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Glucocorticoid

Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.

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HIV

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).

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Hormone

A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.

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Hormone response element

A hormone response element (HRE) is a short sequence of DNA within the promoter of a gene that is able to bind to a specific hormone receptor complex and therefore regulate transcription.

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Human T-lymphotropic virus

The human T-lymphotropic virus, human T-cell lymphotropic virus, or human T-cell leukemia-lymphoma virus (HTLV) family of viruses are a group of human retroviruses that are known to cause a type of cancer called adult T-cell leukemia/lymphoma and a demyelinating disease called HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).

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Jackson Laboratory

The Jackson Laboratory (often abbreviated as JAX) is an independent, nonprofit biomedical research institution dedicated to contributing to a future of better health care based on the unique genetic makeup of each individual.

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John Joseph Bittner

John Joseph Bittner (February 25, 1904 – December 14, 1961) was a geneticist and cancer biologist, who made many contributions on the genetics of breast cancer research, which were of value, not only in cancer research, but also in a variety of other biological investigations.

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Journal of Virology

The Journal of Virology is a biweekly peer-reviewed scientific journal that covers research concerning all aspects of virology.

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Long terminal repeat

Long terminal repeats (LTRs) are identical sequences of DNA that repeat hundreds or thousands of times found at either end of retrotransposons or proviral DNA formed by reverse transcription of retroviral RNA.

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Lymphocyte

A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

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Mouse models of breast cancer metastasis

Breast cancer metastatic mouse models are experimental approaches in which mice are genetically manipulated to develop a mammary tumor leading to distant focal lesions of mammary epithelium.

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Murinae

The Old World rats and mice, part of the subfamily Murinae in the family Muridae, comprise at least 519 species.

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Nature (journal)

Nature is a British multidisciplinary scientific journal, first published on 4 November 1869.

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Oncogene

An oncogene is a gene that has the potential to cause cancer.

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Orthoretrovirinae

Orthoretrovirinae is a subfamily of viruses belonging to Retroviridae, a family of enveloped viruses that replicate in a host cell through the process of reverse transcription.

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Peyer's patch

Peyer's patches (or aggregated lymphoid nodules, or occasionally PP for brevity) are organized lymphoid follicles, named after the 17th-century Swiss anatomist Johann Conrad Peyer.

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Polyomaviridae

Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds.

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Progestin

A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Prolactin

Prolactin (PRL), also known as luteotropic hormone or luteotropin, is a protein that is best known for its role in enabling mammals, usually females, to produce milk.

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Provirus

A provirus is a virus genome that is integrated into the DNA of a host cell.

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Retrovirus

A retrovirus is a single-stranded positive-sense RNA virus with a DNA intermediate and, as an obligate parasite, targets a host cell.

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Rev (HIV)

Rev is a transactivating protein that is essential to the regulation of HIV-1 protein expression.

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Reverse transcriptase

A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Superantigen

Superantigens (SAgs) are a class of antigens that cause non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release.

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T cell

A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.

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T-cell receptor

The T-cell receptor, or TCR, is a molecule found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules.

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Time (magazine)

Time is an American weekly news magazine and news website published in New York City.

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Vertically transmitted infection

A vertically transmitted infection is an infection caused by pathogens (such as bacteria and viruses) that uses mother-to-child transmission, that is, transmission directly from the mother to an embryo, fetus, or baby during pregnancy or childbirth.

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Redirects here:

Bittner factor, MMTV, Mammary tumor virus, mouse, Mouse mammary tumour virus, Prototypic promoter.

References

[1] https://en.wikipedia.org/wiki/Mouse_mammary_tumor_virus

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