37 relations: Agonist, Aldosterone, Binding selectivity, Bioavailability, Biological half-life, Derivative (chemistry), Epimer, Estradiol (medication), Estrane, Estrogen (medication), Estrogen ester, Estrogen receptor, Estrogen receptor alpha, Estrogen receptor beta, Ethinylestradiol, Europe, Hydrocortisone, Isomer, Ligand (biochemistry), Liver, Menopause, Menstrual disorder, Metabolism, Methoxy group, Oral administration, Organic compound, Plasma protein binding, Potency (pharmacology), Progesterone (medication), Radioligand, RU-16117, Scientific method, Serum albumin, Sex hormone-binding globulin, Steroid, Testosterone (medication), Trademark distinctiveness.
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
In stereochemistry, an epimer is one of a pair of stereoisomers.
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
Estrane is a C18 steroid derivative, with a gonane core.
An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
An estrogen ester is an ester of an estrogen, generally of estradiol but also and alternatively of estrone or estriol.
Estrogen receptors (ERs) are a group of proteins found inside cells.
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.
Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.
Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins.
Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.
Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication.
An isomer (from Greek ἰσομερής, isomerès; isos.
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
Menopause, also known as the climacteric, is the time in most women's lives when menstrual periods stop permanently, and they are no longer able to bear children.
A menstrual disorder is an abnormal condition in a woman's menstrual cycle.
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
A methoxy group is the functional group consisting of a methyl group bound to oxygen.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
Plasma protein binding refers to the degree to which medications attach to proteins within the blood.
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
Progesterone is a medication and naturally occurring steroid hormone.
A radioligand is a radioactive biochemical substance (in particular, a ligand that is radiolabeled) that is used for diagnosis or for research-oriented study of the receptor systems of the body.
RU-16117 is an estrogen medication which was investigated for the potential treatment of symptoms of estrogen deficiency such as hot flashes and osteoporosis in women but was never marketed.
Scientific method is an empirical method of knowledge acquisition, which has characterized the development of natural science since at least the 17th century, involving careful observation, which includes rigorous skepticism about what one observes, given that cognitive assumptions about how the world works influence how one interprets a percept; formulating hypotheses, via induction, based on such observations; experimental testing and measurement of deductions drawn from the hypotheses; and refinement (or elimination) of the hypotheses based on the experimental findings.
Serum albumin, often referred to simply as blood albumin, is an albumin (a type of globular protein) found in vertebrate blood.
Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the two sex hormones: androgen and estrogen.
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
Testosterone is a medication and naturally occurring steroid hormone.
Trademark distinctiveness is an important concept in the law governing trademarks and service marks.
11β-MeO-17α-EE, 11β-MeO-EE, ATC code G03CB04, ATCvet code QG03CB04, Moxesterel, Moxesterol, Moxestrel, NSC 118,191, NSC 118191, NSC-118,191, NSC-118191, NSC118191, R 2858, R-2858, R2858, RU 2858, RU-2858, RU2858, Surestryl.