59 relations: Actin, Alternative splicing, Androgen receptor, Assay, Becker's muscular dystrophy, Bioinformatics, C-Met, C2C12, Calcium, Cellular differentiation, Centronuclear myopathy, ChIP-on-chip, Delamination, Delta-like 1, DNA sequencing, Embryo, Embryogenesis, Epaxial and hypaxial muscles, Facial muscles, Fibroblast, Fibroblast growth factor, FOX proteins, Hepatocyte growth factor, High-throughput screening, Hypoplasia, In situ hybridization, LBX1, MCF2, Mef2, Mesoderm, Metalloproteinase, MSX1, MYF5, MYF6, Myocyte, MyoD, Myogenic regulatory factors, Myogenin, Myosatellite cell, Myotome, Neural crest, Notch signaling pathway, Paracrine signalling, PAX3, PAX7, Phosphoinositide 3-kinase, Receptor tyrosine kinase, Regional differentiation, Sarcolemma, Serum response factor, ..., SIX1, Skeletal muscle, Somite, Sonic hedgehog, Systems theory, T-box, TCF4, Twist transcription factor, Waardenburg syndrome. Expand index (9 more) » « Shrink index
Actin is a family of globular multi-functional proteins that form microfilaments.
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
An assay is an investigative (analytic) procedure in laboratory medicine, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity (the analyte).
Becker muscular dystrophy is an X-linked recessive inherited disorder characterized by slowly progressing muscle weakness of the legs and pelvis.
Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data.
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.
C2C12 is an immortalized mouse myoblast cell line.
Calcium is a chemical element with symbol Ca and atomic number 20.
In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.
Centronuclear myopathies (CNM) are a group of congenital myopathies where cell nuclei are abnormally located in skeletal muscle cells.
ChIP-on-chip (also known as ChIP-chip) is a technology that combines chromatin immunoprecipitation ('ChIP') with DNA microarray ("chip").
Christmas is an annual festival commemorating the birth of Jesus Christ,Martindale, Cyril Charles.
The Christmas season, also called the festive season, or the holiday season (mainly in the U.S. and Canada; often simply called the holidays),, is an annually recurring period recognized in many Western and Western-influenced countries that is generally considered to run from late November to early January.
Christmas Eve is the evening or entire day before Christmas Day, the festival commemorating the birth of Jesus.
Christmas traditions vary from country to country.
Delamination is a mode of failure for composite materials and steel.
Delta-like protein 1 is a protein that in humans is encoded by the DLL1 gene.
DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule.
An embryo is an early stage of development of a multicellular diploid eukaryotic organism.
Embryogenesis is the process by which the embryo forms and develops.
Trunk muscles can be broadly divided into hypaxial muscles, which lie ventral to the horizontal septum of the vertebrae and epaxial muscles, which lie dorsal to the septum.
The facial muscles are a group of striated skeletal muscles supplied by the facial nerve (cranial nerve VII) that, among other things, control facial expression.
A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.
The fibroblast growth factors are a family of cell signalling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development.
FOX (Forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity.
Hepatocyte growth factor (HGF) (or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells and T cells. It has been shown to have a major role in embryonic organ development, specifically in myogenesis, in adult organ regeneration, and in wound healing.
High-throughput screening (HTS) is a method for scientific experimentation especially used in drug discovery and relevant to the fields of biology and chemistry.
Hypoplasia (from Ancient Greek ὑπo- hypo-, "under" + πλάσις plasis, "formation"; adjective form hypoplastic) is underdevelopment or incomplete development of a tissue or organ.
In situ hybridization (ISH) is a type of hybridization that uses a labeled complementary DNA, RNA or modified nucleic acids strand (i.e., probe) to localize a specific DNA or RNA sequence in a portion or section of tissue (in situ), or, if the tissue is small enough (e.g., plant seeds, Drosophila embryos), in the entire tissue (whole mount ISH), in cells, and in circulating tumor cells (CTCs).
Transcription factor LBX1 is a protein that in humans is encoded by the LBX1 gene.
Proto-oncogene DBL is a protein that in humans is encoded by the MCF2 gene.
In the field of molecular biology, myocyte enhancer factor-2 (Mef2) proteins are a family of transcription factors which through control of gene expression are important regulators of cellular differentiation and consequently play a critical role in embryonic development.
In all bilaterian animals, the mesoderm is one of the three primary germ layers in the very early embryo.
A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal.
Msh homeobox 1, also known as MSX1, is a protein that in humans is encoded by the MSX1 gene.
Myogenic factor 5 is a protein that in humans is encoded by the MYF5 gene.
Myogenic factor 6 (herculin) is a protein that in humans is encoded by the MYF6 gene.
A myocyte (also known as a muscle cell) is the type of cell found in muscle tissue.
MyoD is a protein that plays a major role in regulating muscle differentiation.
Myogenic regulatory factors (MRF) are basic helix-loop-helix (bHLH) transcription factors that regulate myogenesis: MyoD, Myf5, myogenin, and MRF4.
Myogenin (myogenic factor 4), also known as MYOG, is a gene.
Myosatellite cells or satellite cells are small multipotent cells with virtually no cytoplasm found in mature muscle.
A myotome is the group of muscles that a single spinal nerve innervates.
Neural crest cells are a temporary group of cells unique to chordates of the group Cristozoa that arise from the embryonic ectoderm cell layer, and in turn give rise to a diverse cell lineage—including melanocytes, craniofacial cartilage and bone, smooth muscle, peripheral and enteric neurons and glia.
New Year is the time or day at which a new calendar year begins and the calendar's year count increments by one.
New Year's Day, also called simply New Year's or New Year, is observed on January 1, the first day of the year on the modern Gregorian calendar as well as the Julian calendar.
In the Gregorian calendar, New Year's Eve (also known as Old Year's Day or Saint Sylvester's Day in many countries), the last day of the year, is on 31 December which is the seventh day of Christmastide.
The Notch signaling pathway is a highly conserved cell signaling system present in most multicellular organisms.
Paracrine signaling is a form of cell-to-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior of those cells.
The PAX3 (paired box gene 3) gene encodes a member of the paired box or PAX family of transcription factors.
Paired box protein Pax-7 is a protein that in humans is encoded by the PAX7 gene.
Phosphatidylinositol-4,5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI(3)Ks, PI-3Ks or by the HUGO official stem symbol for the gene family, PI3K(s)) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones.
In the field of developmental biology, regional differentiation is the process by which different areas are identified in the development of the early embryo.
The sarcolemma (sarco (from sarx) from Greek; flesh, and lemma from Greek; sheath) also called the myolemma, is the cell membrane of a striated muscle fiber cell.
Serum response factor, also known as SRF, is a transcription factor protein.
Homeobox protein SIX1 (Sineoculis homeobox homolog 1) is a protein that in humans is encoded by the SIX1 gene.
Skeletal muscle is one of three major muscle types, the others being cardiac muscle and smooth muscle.
Somites (outdated: primitive segments) are divisions of the body of an animal or embryo.
Sonic hedgehog is a protein that in humans is encoded by the SHH ("sonic hedgehog") gene.
Systems theory is the interdisciplinary study of systems.
T-box refers to a group of transcription factors involved in limb and heart development.
Transcription factor 4 (TCF-4) also known as immunoglobulin transcription factor 2 (ITF-2) is a protein that in humans is encoded by the TCF4 gene located on chromosome 18q21.2.
Twist-related protein 1 (TWIST1) also known as class A basic helix-loop-helix protein 38 (bHLHa38) is a basic helix-loop-helix transcription factor that in humans is encoded by the TWIST1 gene.
Waardenburg syndrome is a rare genetic disorder most often characterized by varying degrees of deafness, minor defects in structures arising from the neural crest, and pigmentation changes.
2018 has been designated as the third International Year of the Reef by the International Coral Reef Initiative.
2019 (MMXIX) will be a common year starting on Tuesday of the Gregorian calendar, the 2019th year of the Common Era (CE) and Anno Domini (AD) designations, the 19th year of the 3rd millennium, the 19th year of the 21st century, and the 10th and last year of the 2010s decade.