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NNC 45-0095

Index NNC 45-0095

NC 45-0095 is a synthetic nonsteroidal selective estrogen receptor modulator (SERM) which was under development by Novo Nordisk for the treatment of postmenopausal osteoporosis but was never marketed. [1]

19 relations: Antiestrogen, Bone, Derivative (chemistry), Endometrial cancer, Estrogen (medication), Estrogen receptor, Immortalised cell line, Indolizine, List of selective estrogen receptor modulators, Molecular binding, Moxestrol, Nonsteroidal, Novo Nordisk, Organic compound, Osteoporosis, Partial agonist, Pyrrole, Selective estrogen receptor modulator, Uterus.

Antiestrogen

Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body.

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Bone

A bone is a rigid organ that constitutes part of the vertebrate skeleton.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Endometrial cancer

Endometrial cancer is a cancer that arises from the endometrium (the lining of the uterus or womb).

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Estrogen (medication)

An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Estrogen receptor

Estrogen receptors (ERs) are a group of proteins found inside cells.

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Immortalised cell line

An immortalized cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division.

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Indolizine

Indolizine (Chemical formula C8H7N) is a heterocyclic aromatic organic compound that is an isomer of indole.

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List of selective estrogen receptor modulators

This is a list of selective estrogen receptor modulators (SERMs).

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Molecular binding

Molecular binding is an attractive interaction between two molecules that results in a stable association in which the molecules are in close proximity to each other.

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Moxestrol

Moxestrol, sold under the brand name Surestryl, is an estrogen medication which is or was used in Europe for the treatment of menopausal symptoms and menstrual disorders.

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Nonsteroidal

Nonsteroidal is a term which is used to describe a compound that is not a steroid.

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Novo Nordisk

Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsværd, Denmark, with production facilities in eight countries, and affiliates or offices in 75 countries.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Osteoporosis

Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.

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Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

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Pyrrole

Pyrrole is a heterocyclic aromatic organic compound, a five-membered ring with the formula C4H4NH.

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Selective estrogen receptor modulator

Selective estrogen receptor modulators (SERMs) are a class of drugs that act on the estrogen receptor (ER).

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Uterus

The uterus (from Latin "uterus", plural uteri) or womb is a major female hormone-responsive secondary sex organ of the reproductive system in humans and most other mammals.

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Redirects here:

C18H15NO, NNC 450095, NNC-45-0095, NNC-450095, NNC45-0095, NNC450095.

References

[1] https://en.wikipedia.org/wiki/NNC_45-0095

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