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13 relations: Afimoxifene, Bisphenol A, Diethylstilbestrol, Dissociation constant, Endocrine disruptor, Estrogen receptor, Gene, Inverse agonist, Nuclear receptor, Orphan receptor, Placenta, Selective estrogen receptor modulator, Steroid hormone receptor.
Afimoxifene
Afimoxifene, also known as 4-hydroxytamoxifen (4-OHT, 4-HT, OHTAM, others), is a selective estrogen receptor modulator (SERM) of the triphenylethylene group and the major active metabolite of tamoxifen.
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Bisphenol A
Bisphenol A (BPA) is an organic synthetic compound with the chemical formula (CH3)2C(C6H4OH)2 belonging to the group of diphenylmethane derivatives and bisphenols, with two hydroxyphenyl groups.
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Diethylstilbestrol
Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is an estrogen medication which is mostly no longer used.
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Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant (K_d) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.
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Endocrine disruptor
Endocrine disruptors are chemicals that can interfere with endocrine (or hormone) systems at certain doses.
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Estrogen receptor
Estrogen receptors (ERs) are a group of proteins found inside cells.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Inverse agonist
In the field of pharmacology, an inverse agonist is an agent that binds to the same receptor as an agonist but induces a pharmacological response opposite to that agonist.
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Nuclear receptor
In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules.
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Orphan receptor
In biochemistry, an orphan receptor is a protein that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified.
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Placenta
The placenta is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, thermo-regulation, waste elimination, and gas exchange via the mother's blood supply; to fight against internal infection; and to produce hormones which support pregnancy.
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Selective estrogen receptor modulator
Selective estrogen receptor modulators (SERMs) are a class of drugs that act on the estrogen receptor (ER).
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Steroid hormone receptor
Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells.
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Redirects here:
ERR-gamma, ERRγ, ESRRG, ESRRG (gene), Estrogen-related receptor γ, NR3B3.
References
[1] https://en.wikipedia.org/wiki/Estrogen-related_receptor_gamma
