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59 relations: Activated carbon, Active metabolite, Acute (medicine), Analgesic, Aspirin, Beta blocker, Bioavailability, Biological half-life, Calcium channel, Carbon, Chronic pain, Convulsion, Cyclic compound, Demethylation, Diphenhydramine, Dopamine, Drug overdose, Elimination (pharmacology), Erythema multiforme, Feces, Glutamic acid, Hallucination, Hiccup, Hyperdynamic circulation, Hypertensive crisis, Intramuscular injection, Intravenous therapy, Isocarboxazid, Liver, Mechanism of action, Metabolic pathway, Metabolism, Monoamine oxidase inhibitor, Myocardial infarction, Neurotransmitter, Norepinephrine, Oral administration, Orphenadrine, Oxycodone, Pharmacodynamics, Phenelzine, Plasma protein binding, Reuptake, Reuptake inhibitor, Ring (chemistry), Serotonin, Serotonin syndrome, Sodium channel, Structural analog, Substance abuse, ..., Tachycardia, Tofenacin, Tranylcypromine, Tricyclic antidepressant, Urinary retention, Urine, 5-HT2A receptor, 5-HT2B receptor, 5-HT2C receptor. Expand index (9 more) »
Activated carbon
Activated carbon, also called activated charcoal, is a form of carbon processed to have small, low-volume pores that increase the surface area available for adsorption or chemical reactions.
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Active metabolite
An active metabolite is an active form of a drug after it has been processed by the body.
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Acute (medicine)
In medicine, describing a disease as acute denotes that it is of short duration and, as a corollary of that, of recent onset.
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Analgesic
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.
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Aspirin
Aspirin, also known as acetylsalicylic acid (ASA), is a medication used to treat pain, fever, or inflammation.
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Beta blocker
Beta blockers, also written β-blockers, are a class of medications that are particularly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack (myocardial infarction) after a first heart attack (secondary prevention).
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Bioavailability
In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.
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Biological half-life
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
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Calcium channel
A calcium channel is an ion channel which shows selective permeability to calcium ions.
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Carbon
Carbon (from carbo "coal") is a chemical element with symbol C and atomic number 6.
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Chronic pain
Chronic pain is pain that lasts a long time.
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Convulsion
A convulsion is a medical condition where body muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body.
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Cyclic compound
A cyclic compound (ring compound) is a term for a compound in the field of chemistry in which one or more series of atoms in the compound is connected to form a ring.
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Demethylation
Demethylation is the chemical process resulting in the removal of a methyl group (CH3) from a molecule.
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Diphenhydramine
Diphenhydramine is an antihistamine mainly used to treat allergies.
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Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
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Drug overdose
The term drug overdose (or simply overdose or OD) describes the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced.
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Elimination (pharmacology)
In pharmacology the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared and excreted) from an organism either in an unaltered form (unbound molecules) or modified as a metabolite.
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Erythema multiforme
Erythema multiforme (EM) is a skin condition of unknown cause; it is a type of erythema possibly mediated by deposition of immune complexes (mostly IgM-bound complexes) in the superficial microvasculature of the skin and oral mucous membrane that usually follows an infection or drug exposure.
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Feces
Feces (or faeces) are the solid or semisolid remains of the food that could not be digested in the small intestine.
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Glutamic acid
Glutamic acid (symbol Glu or E) is an α-amino acid with formula.
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Hallucination
A hallucination is a perception in the absence of external stimulus that has qualities of real perception.
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Hiccup
A hiccup (also spelled hiccough) is an involuntary contraction (myoclonic jerk) of the diaphragm that may repeat several times per minute.
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Hyperdynamic circulation
Hyperdynamic circulation is abnormally increased circulatory volume.
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Hypertensive crisis
Severely elevated blood pressure (equal to or greater than a systolic 180 or diastolic of 110—sometimes termed malignant or accelerated hypertension) is referred to as a hypertensive crisis, as blood pressure at this level confers a high risk of complications.
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Intramuscular injection
Intramuscular (also IM or im) injection is the injection of a substance directly into muscle.
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Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
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Isocarboxazid
Isocarboxazid (Marplan, Marplon, Enerzer) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class used as an antidepressant.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Mechanism of action
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.
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Metabolic pathway
In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell.
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Metabolism
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
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Monoamine oxidase inhibitor
Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).
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Myocardial infarction
Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.
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Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
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Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
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Oral administration
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Orphenadrine
Orphenadrine (sold under many brand names worldwide Page accessed Feb 5, 2016) is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine.
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Oxycodone
Oxycodone, sold under brand names such as Percocet and OxyContin among many others, is an opioid medication which is used for the relief of moderate to severe pain.
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Pharmacodynamics
Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).
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Phenelzine
Phenelzine (Nardil, Nardelzine) is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is used as an antidepressant and anxiolytic.
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Plasma protein binding
Plasma protein binding refers to the degree to which medications attach to proteins within the blood.
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Reuptake
Reuptake is the reabsorption of a neurotransmitter by a neurotransmitter transporter located along the plasma membrane of an axon terminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it has performed its function of transmitting a neural impulse.
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Reuptake inhibitor
A reuptake inhibitor (RI) is a type of drug known as a reuptake modulator that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic neuron.
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Ring (chemistry)
In chemistry, a ring is an ambiguous term referring either to a simple cycle of atoms and bonds in a molecule or to a connected set of atoms and bonds in which every atom and bond is a member of a cycle (also called a ring system).
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Serotonin
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
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Serotonin syndrome
Serotonin syndrome (SS) is a group of symptoms that may occur following use of certain serotonergic medications or drugs.
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Sodium channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
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Structural analog
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
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Substance abuse
Substance abuse, also known as drug abuse, is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others, and is a form of substance-related disorder.
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Tachycardia
Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.
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Tofenacin
Tofenacin is an antidepressant drug with a tricyclic-like structure which was developed and marketed in the United Kingdom and Italy in 1971 and 1981, respectively, by Brocades-Stheeman & Pharmacia (now part of Astellas Pharma).
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Tranylcypromine
Tranylcypromine (contracted from trans-2-phenylcyclopropylamine; original trade name Parnate)Drugs.com.
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Tricyclic antidepressant
Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants.
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Urinary retention
Urinary retention is an inability to completely empty the bladder.
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Urine
Urine is a liquid by-product of metabolism in humans and in many animals.
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5-HT2A receptor
The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).
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5-HT2B receptor
5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene.
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5-HT2C receptor
The 5-HT2C receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).
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Redirects here:
ATC code N02BG06, ATCvet code QN02BG06.
References
[1] https://en.wikipedia.org/wiki/Nefopam
