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Action potential

Index Action potential

In physiology, an action potential occurs when the membrane potential of a specific axon location rapidly rises and falls: this depolarisation then causes adjacent locations to similarly depolarise. [1]

263 relations: Acetabularia, Acetylcholine, Acetylcholinesterase, Affinity chromatography, Afterhyperpolarization, Alan Lloyd Hodgkin, Alessandro Volta, Algae, All-or-none law, Amacrine cell, Amplitude, Andrew Huxley, Animal, Anode break excitation, Antidromic, Artificial neural network, Atrioventricular node, Atrium (heart), Axon, Axon hillock, Axon terminal, Ångström, Balthasar van der Pol, Bernard Katz, Bert Sakmann, Bertil Hille, Beta blocker, Beta cell, Biological neuron model, Bipolar neuron, Botulinum toxin, Botulism, Bundle of His, Bursting, Cable theory, Calcium, Calcium channel, Calcium imaging, Camillo Golgi, Capacitance, Cardiac action potential, Cardiac muscle cell, Cardiac pacemaker, Carlo Matteucci, Cat, Cell (biology), Cell membrane, Cell nucleus, Cell–cell interaction, Central nervous system, ..., Central pattern generator, Cerebellum, Cerebral cortex, Chemical synapse, Chemical warfare, Chloride, Chronaxie, Computational model, Connexon, Cryogenic electron microscopy, David E. Goldman, Dendrite, Dendritic spine, Dendrotoxin, Depolarization, Development of the nervous system, Diazinon, Differential equation, Digital electronics, Dinoflagellate, Direct current, Dynamical system, Ear, Electric battery, Electric eel, Electrical synapse, Electrode, Electrotonic potential, Emil du Bois-Reymond, Endocrine system, EOSFET, Erwin Neher, Escape reflex, Eukaryote, Excitatory postsynaptic potential, Exocytosis, Extracellular fluid, Factor of safety, Faraday cage, FitzHugh–Nagumo model, Fluid compartments, Frequency, Frog, Frog battery, Fungus, Gap junction, Gating (electrophysiology), Goldman equation, Gonyaulax, Graded potential, Granule cell, Hair cell, Heart, Heart arrhythmia, Heart rate, Hermann von Helmholtz, Hodgkin–Huxley model, Hydrolysis, Hyperpolarization (biology), Ichiji Tasaki, Inhibitory postsynaptic potential, Input impedance, Insect, Insecticide, Insulin, Invertebrate, Ion, Ion channel, Ion transporter, John Eccles (neurophysiologist), Julius Bernstein, Kenneth Stewart Cole, Knut Schmidt-Nielsen, Lamellar corpuscle, Lateral geniculate nucleus, Lidocaine, Ligand-gated ion channel, Lipid bilayer, Loligo forbesii, Longfin inshore squid, Louis Lapicque, Luigi Galvani, Malathion, Mamba, Mammal, Mechanoreceptor, Mechanosensitive channels, Medical optical imaging, Membrane potential, Metre per second, Micrometre, Mimosa pudica, Mitosis, Morris–Lecar model, Motor neuron, Multicellular organism, Multiple sclerosis, Myelin, Myocyte, Na+/K+-ATPase, Nanometre, Natural selection, Nernst equation, Nerve, Nerve agent, Nerve conduction velocity, Neural accommodation, Neural computation, Neural oscillation, Neuroanatomy, Neurochip, Neuroglia, Neuromuscular junction, Neuron, Neurospora crassa, Neurotoxin, Neurotransmitter, Nobel Prize in Physiology or Medicine, Node of Ranvier, Noise (electronics), Olfaction, Olfactory receptor neuron, Oligodendrocyte, Optic nerve, Ordinary differential equation, Orthodromic, Osmosis, Pacemaker potential, Pancreas, Paralytic shellfish poisoning, Parasympathetic nervous system, Partial differential equation, Patch clamp, Peripheral nervous system, Permeation, Permethrin, Photoreceptor cell, Phylum, Physiology, Plant, Plant cell, Positive feedback, Potassium, Potassium channel, Principles of Neural Science, Purkinje cell, Purkinje fibers, Pyramidal cell, Quinidine, Receptor potential, Reflex, Refractory period (physiology), Reptile, Resting potential, Retina, Retina horizontal cell, Retinal ganglion cell, Saltatory conduction, Santiago Ramón y Cajal, Sarcolemma, Sarin, Saxitoxin, Schwann cell, Sensory neuron, Shrimp, Single-unit recording, Sinoatrial node, SK channel, Sodium, Sodium channel, Soliton model in neuroscience, Soma (biology), Somatosensory system, SourceForge, Speed of sound, Spike-timing-dependent plasticity, Sponge, Squid, Squid giant axon, Summation (neurophysiology), Sympathetic nervous system, Synapse, Synaptic potential, Synaptic vesicle, Tabun (nerve agent), Tactile corpuscle, Tetanospasmin, Tetanus, Tetraodontidae, Tetrodotoxin, Threshold potential, Time constant, Transcription (biology), Translation (biology), Trigger zone, Tropomyosin, Two-pore-domain potassium channel, University of Arizona, Ventricle (heart), Verapamil, Vertebrate, Voltage, Voltage clamp, Voltage-gated ion channel, Voltage-gated potassium channel, Voltage-sensitive dye, Voltaic pile, W. A. H. Rushton, Wiley-Blackwell, Wilfrid Rall, William Thomson, 1st Baron Kelvin, X-ray crystallography, Xenopus. Expand index (213 more) »

Acetabularia

Acetabularia is a genus of green algae in the family Polyphysaceae, Typically found in subtropical waters, Acetabularia is a single-celled organism, but gigantic in size and complex in form, making it an excellent model organism for studying cell biology.

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Acetylcholine

Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells.

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Acetylcholinesterase

Acetylcholinesterase, encoded by HGNC gene ACHE; EC 3.1.1.7) is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

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Affinity chromatography

Affinity chromatography is a method of separating biochemical mixtures based on a highly specific interaction between antigen and antibody, enzyme and substrate, receptor and ligand, or protein and nucleic acid.

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Afterhyperpolarization

Afterhyperpolarization, or AHP, is the hyperpolarizing phase of a neuron's action potential where the cell's membrane potential falls below the normal resting potential.

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Alan Lloyd Hodgkin

Sir Alan Lloyd Hodgkin (5 February 1914 – 20 December 1998) was an English physiologist and biophysicist, who shared the 1963 Nobel Prize in Physiology or Medicine with Andrew Huxley and John Eccles.

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Alessandro Volta

Alessandro Giuseppe Antonio Anastasio Volta (18 February 1745 – 5 March 1827) was an Italian physicist, chemist, and a pioneer of electricity and power,Giuliano Pancaldi, "Volta: Science and culture in the age of enlightenment", Princeton University Press, 2003.

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Algae

Algae (singular alga) is an informal term for a large, diverse group of photosynthetic organisms that are not necessarily closely related, and is thus polyphyletic.

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All-or-none law

The all-or-none law is the principle that the strength by which a nerve or muscle fibre responds to a stimulus is independent of the strength of the stimulus.

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Amacrine cell

Amacrine cells are interneurons in the retina.

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Amplitude

The amplitude of a periodic variable is a measure of its change over a single period (such as time or spatial period).

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Andrew Huxley

Sir Andrew Fielding Huxley (22 November 191730 May 2012) was a Nobel Prize-winning English physiologist and biophysicist.

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Animal

Animals are multicellular eukaryotic organisms that form the biological kingdom Animalia.

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Anode break excitation

Anode break excitation (ABE) is an electrophysiological phenomenon whereby a neuron fires action potentials in response to termination of a hyperpolarizing current.

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Antidromic

An antidromic impulse in an axon refers to conduction opposite of the normal (orthodromic) direction.

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Artificial neural network

Artificial neural networks (ANNs) or connectionist systems are computing systems vaguely inspired by the biological neural networks that constitute animal brains.

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Atrioventricular node

The atrioventricular node, or AV node is a part of the electrical conduction system of the heart that coordinates the top of the heart.

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Atrium (heart)

The atrium is the upper chamber in which blood enters the heart.

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Axon

An axon (from Greek ἄξων áxōn, axis) or nerve fiber, is a long, slender projection of a nerve cell, or neuron, that typically conducts electrical impulses known as action potentials, away from the nerve cell body.

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Axon hillock

The axon hillock is a specialized part of the cell body (or soma) of a neuron that connects to the axon.

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Axon terminal

Axon terminals (also called synaptic boutons or terminal boutons) are distal terminations of the telodendria (branches) of an axon.

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Ångström

The ångström or angstrom is a unit of length equal to (one ten-billionth of a metre) or 0.1 nanometre.

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Balthasar van der Pol

Balthasar van der Pol (27 January 1889 – 6 October 1959) was a Dutch physicist.

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Bernard Katz

Sir Bernard Katz, FRS (26 March 1911 – 20 April 2003) was a German-born Australian physician and biophysicist, noted for his work on nerve physiology.

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Bert Sakmann

Bert Sakmann (born 12 June 1942) is a German cell physiologist.

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Bertil Hille

Bertil Hille (born October 10, 1940) is a professor in the Department of Physiology and Biophysics at the University of Washington.

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Beta blocker

Beta blockers, also written β-blockers, are a class of medications that are particularly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack (myocardial infarction) after a first heart attack (secondary prevention).

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Beta cell

Beta cells (β cells) are a type of cell found in the pancreatic islets of the pancreas.

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Biological neuron model

A biological neuron model, also known as a spiking neuron model, is a mathematical description of the properties of certain cells in the nervous system that generate sharp electrical potentials across their cell membrane, roughly one millisecond in duration, as shown in Fig.

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Bipolar neuron

A bipolar neuron or bipolar cell, is a type of neuron which has two extensions.

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Botulinum toxin

Botulinum toxin (BTX) or Botox is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species.

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Botulism

Botulism is a rare and potentially fatal illness caused by a toxin produced by the bacterium Clostridium botulinum.

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Bundle of His

The bundle of His or His bundle is a collection of heart muscle cells specialized for electrical conduction.

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Bursting

Bursting, or burst firing, is an extremely diverse general phenomenon of the activation patterns of neurons in the central nervous system and spinal cord where periods of rapid action potential spiking are followed by G0 phase quiescent periods.

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Cable theory

Classical cable theory uses mathematical models to calculate the electric current (and accompanying voltage) along passive neurites, particularly the dendrites that receive synaptic inputs at different sites and times.

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Calcium

Calcium is a chemical element with symbol Ca and atomic number 20.

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Calcium channel

A calcium channel is an ion channel which shows selective permeability to calcium ions.

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Calcium imaging

Calcium imaging is a scientific technique usually carried out in research which is designed to show the calcium (Ca2+) status of an isolated cell, tissue or medium.

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Camillo Golgi

Camillo Golgi (7 July 1843 – 21 January 1926) was an Italian biologist and pathologist known for his works on the central nervous system.

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Capacitance

Capacitance is the ratio of the change in an electric charge in a system to the corresponding change in its electric potential.

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Cardiac action potential

The cardiac action potential is a brief change in voltage (membrane potential) across the cell membrane of heart cells.

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Cardiac muscle cell

Cardiac muscle cells or cardiomyocytes (also known as myocardiocytes or cardiac myocytes) are the muscle cells (myocytes) that make up the cardiac muscle (heart muscle).

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Cardiac pacemaker

Image showing the cardiac pacemaker or SA node, the normal pacemaker within the electrical conduction system of the heart. The contraction of cardiac muscle (heart muscle) in all animals is initiated by electrical impulses known as action potentials.

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Carlo Matteucci

Carlo Matteucci (21 June 1811 – 25 June 1868) was an Italian physicist and neurophysiologist who was a pioneer in the study of bioelectricity.

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Cat

The domestic cat (Felis silvestris catus or Felis catus) is a small, typically furry, carnivorous mammal.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Cell nucleus

In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.

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Cell–cell interaction

Cell–cell interaction refers to the direct interactions between cell surfaces that play a crucial role in the development and function of multicellular organisms.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Central pattern generator

Central pattern generators (CPGs) are biological neural circuits that produce rhythmic outputs in the absence of rhythmic input.

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Cerebellum

The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates.

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Cerebral cortex

The cerebral cortex is the largest region of the cerebrum in the mammalian brain and plays a key role in memory, attention, perception, cognition, awareness, thought, language, and consciousness.

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Chemical synapse

Chemical synapses are biological junctions through which neurons' signals can be exchanged to each other and to non-neuronal cells such as those in muscles or glands.

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Chemical warfare

Chemical warfare (CW) involves using the toxic properties of chemical substances as weapons.

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Chloride

The chloride ion is the anion (negatively charged ion) Cl−.

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Chronaxie

Chronaxie is the minimum time required for an electric current double the strength of the rheobase to stimulate a muscle or a neuron.

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Computational model

A computational model is a mathematical model in computational science that requires extensive computational resources to study the behavior of a complex system by computer simulation.

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Connexon

In biology, a connexon, also known as a connexin hemichannel, is an assembly of six proteins called connexins that form the pore for a gap junction between the cytoplasm of two adjacent cells.

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Cryogenic electron microscopy

Electron cryomicroscopy (CryoEM) is an electron microscopy (EM) technique where the sample is cooled to cryogenic temperatures.

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David E. Goldman

David E. Goldman (1910–1998) was a scientist famous for the Goldman equation which he derived for his doctorate degree in 1943 at Columbia University.

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Dendrite

Dendrites (from Greek δένδρον déndron, "tree"), also dendrons, are branched protoplasmic extensions of a nerve cell that propagate the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.

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Dendritic spine

A dendritic spine (or spine) is a small membranous protrusion from a neuron's dendrite that typically receives input from a single axon at the synapse.

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Dendrotoxin

Dendrotoxins are a class of presynaptic neurotoxins produced by mamba snakes (Dendroaspis) that block particular subtypes of voltage-gated potassium channels in neurons, thereby enhancing the release of acetylcholine at neuromuscular junctions.

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Depolarization

In biology, depolarization is a change within a cell, during which the cell undergoes a shift in electric charge distribution, resulting in less negative charge inside the cell.

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Development of the nervous system

Development of the nervous system refers to the processes that generate, shape, and reshape the nervous system of animals, from the earliest stages of embryogenesis to adulthood.

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Diazinon

Diazinon (IUPAC name: O,O-Diethyl O- phosphorothioate, INN - Dimpylate), a colorless to dark brown liquid, is a thiophosphoric acid ester developed in 1952 by Ciba-Geigy, a Swiss chemical company (later Novartis and then Syngenta).

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Differential equation

A differential equation is a mathematical equation that relates some function with its derivatives.

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Digital electronics

Digital electronics or digital (electronic) circuits are electronics that operate on digital signals.

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Dinoflagellate

The dinoflagellates (Greek δῖνος dinos "whirling" and Latin flagellum "whip, scourge") are a large group of flagellate eukaryotes that constitute the phylum Dinoflagellata.

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Direct current

Direct current (DC) is the unidirectional flow of electric charge.

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Dynamical system

In mathematics, a dynamical system is a system in which a function describes the time dependence of a point in a geometrical space.

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Ear

The ear is the organ of hearing and, in mammals, balance.

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Electric battery

An electric battery is a device consisting of one or more electrochemical cells with external connections provided to power electrical devices such as flashlights, smartphones, and electric cars.

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Electric eel

The electric eel (Electrophorus electricus) is a South American electric fish, and the only species in its genus.

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Electrical synapse

An electrical synapse is a mechanical and electrically conductive link between two neighboring neurons that is formed at a narrow gap between the pre- and postsynaptic neurons known as a gap junction.

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Electrode

An electrode is an electrical conductor used to make contact with a nonmetallic part of a circuit (e.g. a semiconductor, an electrolyte, a vacuum or air).

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Electrotonic potential

In physiology, electrotonus refers to the passive spread of charge inside a neuron.

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Emil du Bois-Reymond

Prof.

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Endocrine system

The endocrine system is a chemical messenger system consisting of hormones, the group of glands of an organism that carry those hormones directly into the circulatory system to be carried towards distant target organs, and the feedback loops of homeostasis that the hormones drive.

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EOSFET

An EOSFET or electrolyte–oxide–semiconductor field-effect transistor is a FET, like a MOSFET, but with the metal replaced by electrolyte solution for the detection of neuronal activity.

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Erwin Neher

Erwin Neher (born 20 March 1944) is a German biophysicist, specializing in the field of cell physiology.

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Escape reflex

Escape reflex, a kind of escape response, is a simple reflectory reaction in response to stimuli indicative of danger, that initiates an escape motion of an animal.

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Eukaryote

Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

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Excitatory postsynaptic potential

In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential.

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Exocytosis

Exocytosis is a form of active transport in which a cell transports molecules (e.g., neurotransmitters and proteins) out of the cell (exo- + cytosis) by expelling them through an energy-dependent process.

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Extracellular fluid

Extracellular fluid (ECF) denotes all body fluid outside the cells.

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Factor of safety

Factors of safety (FoS), is also known as (and used interchangeably with) safety factor (SF), is a term describing the load carrying capacity of a system beyond the expected or actual loads.

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Faraday cage

A Faraday cage or Faraday shield is an enclosure used to block electromagnetic fields.

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FitzHugh–Nagumo model

The FitzHugh–Nagumo model (FHN), named after Richard FitzHugh (1922–2007) who suggested the system in 1961 and J. Nagumo et al.

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Fluid compartments

The human body and even its individual body fluids may be conceptually divided into various fluid compartments, which, although not literally anatomic compartments, do represent a real division in terms of how portions of the body's water, solutes, and suspended elements are segregated.

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Frequency

Frequency is the number of occurrences of a repeating event per unit of time.

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Frog

A frog is any member of a diverse and largely carnivorous group of short-bodied, tailless amphibians composing the order Anura (Ancient Greek ἀν-, without + οὐρά, tail).

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Frog battery

A frog battery is an electrochemical battery consisting of a number of dead frogs (or sometimes live ones), which form the cells of the battery connected in a series arrangement.

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Fungus

A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

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Gap junction

A gap junction may also be called a nexus or macula communicans.

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Gating (electrophysiology)

In electrophysiology, the term gating refers to the opening (activation) or closing (by deactivation or inactivation) of ion channels.

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Goldman equation

The Goldman–Hodgkin–Katz voltage equation, more commonly known as the Goldman equation, is used in cell membrane physiology to determine the reversal potential across a cell's membrane, taking into account all of the ions that are permeant through that membrane.

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Gonyaulax

Gonyaulax is a genus of dinoflagellates with the type species Gonyaulax spinifera (Claparède et Lachmann) Diesing.

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Graded potential

Graded potentials are changes in membrane potential that vary in size, as opposed to being all-or-none.

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Granule cell

The name granule cell has been used by anatomists for a number of different types of neuron whose only common feature is that they all have very small cell bodies.

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Hair cell

Hair cells are the sensory receptors of both the auditory system and the vestibular system in the ears of all vertebrates.

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Heart

The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system.

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Heart arrhythmia

Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.

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Heart rate

Heart rate is the speed of the heartbeat measured by the number of contractions of the heart per minute (bpm).

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Hermann von Helmholtz

Hermann Ludwig Ferdinand von Helmholtz (August 31, 1821 – September 8, 1894) was a German physician and physicist who made significant contributions in several scientific fields.

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Hodgkin–Huxley model

The Hodgkin–Huxley model, or conductance-based model, is a mathematical model that describes how action potentials in neurons are initiated and propagated.

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Hydrolysis

Hydrolysis is a term used for both an electro-chemical process and a biological one.

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Hyperpolarization (biology)

Hyperpolarization is a change in a cell's membrane potential that makes it more negative.

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Ichiji Tasaki

was a Japanese-born American biophysicist and physician involved in research relating to the electrical impulses in the nervous system.

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Inhibitory postsynaptic potential

An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.

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Input impedance

The input impedance of an electrical network is the measure of the opposition to current flow (impedance), both static (resistance) and dynamic (reactance), into the load network being that is external to the electrical source.

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Insect

Insects or Insecta (from Latin insectum) are hexapod invertebrates and the largest group within the arthropod phylum.

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Insecticide

Insecticides are substances used to kill insects.

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Insulin

Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.

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Invertebrate

Invertebrates are animals that neither possess nor develop a vertebral column (commonly known as a backbone or spine), derived from the notochord.

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Ion

An ion is an atom or molecule that has a non-zero net electrical charge (its total number of electrons is not equal to its total number of protons).

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Ion channel

Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore.

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Ion transporter

In biology, an ion transporter (or ion pump) is a transmembrane protein that moves ions across a plasma membrane against their concentration gradient through active transport.

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John Eccles (neurophysiologist)

Sir John Carew Eccles (27 January 1903 – 2 May 1997) was an Australian neurophysiologist and philosopher who won the 1963 Nobel Prize in Physiology or Medicine for his work on the synapse.

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Julius Bernstein

Julius Bernstein (18 December 1839 – 6 February 1917) was a German physiologist born in Berlin.

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Kenneth Stewart Cole

Kenneth Stewart Cole (July 10, 1900 – April 18, 1984) was an American biophysicist described by his peers as "a pioneer in the application of physical science to biology".

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Knut Schmidt-Nielsen

Knut Schmidt-Nielsen (September 24, 1915 – January 25, 2007) was a prominent figure in the field of comparative physiology and Professor of Physiology Emeritus at Duke University.

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Lamellar corpuscle

Lamellar corpuscles, or Pacinian corpuscles, are one of the four major types of mechanoreceptor cell in glabrous (hairless) mammalian skin.

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Lateral geniculate nucleus

The lateral geniculate nucleus (LGN; also called the lateral geniculate body or lateral geniculate complex) is a relay center in the thalamus for the visual pathway.

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Lidocaine

Lidocaine, also known as xylocaine and lignocaine, is a medication used to numb tissue in a specific area.

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Ligand-gated ion channel

Ligand-gated ion channels (LICs, LGIC), also commonly referred as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na+, K+, Ca2+, and/or Cl− to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.

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Lipid bilayer

The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules.

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Loligo forbesii

Loligo forbesii (sometimes erroneouslyBouchet, P. and S. Gofas. (2013). World Register of Marine Species. Accessed 5 June 2013. spelled forbesi), known commonly as the veined squid and long-finned squid, is a commercially important species of squid in the family Loliginidae, the pencil squids.

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Longfin inshore squid

The longfin inshore squid (Doryteuthis pealeii) is a species of squid of the family Loliginidae.

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Louis Lapicque

Louis Édouard Lapicque (1 August 1866 – 6 December 1952) was a French neuroscientist, socialist activist, antidreyfusard and freemason who was very influential in the early 20th century.

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Luigi Galvani

Luigi Aloisio Galvani (Aloysius Galvanus; 9 September 1737 – 4 December 1798) was an Italian physician, physicist, biologist and philosopher, who discovered animal electricity.

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Malathion

Malathion is an organophosphate insecticide which acts as an acetylcholinesterase inhibitor.

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Mamba

Mambas are fast-moving venomous snakes of the genus Dendroaspis (which literally means "tree asp") in the family Elapidae.

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Mammal

Mammals are the vertebrates within the class Mammalia (from Latin mamma "breast"), a clade of endothermic amniotes distinguished from reptiles (including birds) by the possession of a neocortex (a region of the brain), hair, three middle ear bones, and mammary glands.

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Mechanoreceptor

A mechanoreceptor is a sensory receptor that responds to mechanical pressure or distortion.

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Mechanosensitive channels

Mechanosensitive channels, mechanosensitive ion channels or stretch-gated ion channels.

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Medical optical imaging

Medical optical imaging is the use of light as an investigational imaging technique for medical applications.

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Membrane potential

The term "membrane potential" may refer to one of three kinds of membrane potential.

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Metre per second

Metre per second (American English: meter per second) is an SI derived unit of both speed (scalar) and velocity (vector quantity which specifies both magnitude and a specific direction), defined by distance in metres divided by time in seconds.

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Micrometre

The micrometre (International spelling as used by the International Bureau of Weights and Measures; SI symbol: μm) or micrometer (American spelling), also commonly known as a micron, is an SI derived unit of length equaling (SI standard prefix "micro-".

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Mimosa pudica

Mimosa pudica (from pudica "shy, bashful or shrinking"; also called sensitive plant, sleepy plant, action plant, Dormilones, touch-me-not, shameplant, or shy plant) is a creeping annual or perennial flowering plant of the pea/legume family Fabaceae and Magnoliopsida taxon, often grown for its curiosity value: the compound leaves fold inward and droop when touched or shaken, defending themselves from harm, and re-open a few minutes later.

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Mitosis

In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.

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Morris–Lecar model

The Morris–Lecar model is a biological neuron model developed by Catherine Morris and Harold Lecar to reproduce the variety of oscillatory behavior in relation to Ca++ and K+ conductance in the muscle fiber of the giant barnacle.

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Motor neuron

A motor neuron (or motoneuron) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands.

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Multicellular organism

Multicellular organisms are organisms that consist of more than one cell, in contrast to unicellular organisms.

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Multiple sclerosis

Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.

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Myelin

Myelin is a lipid-rich substance that surrounds the axon of some nerve cells, forming an electrically insulating layer.

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Myocyte

A myocyte (also known as a muscle cell) is the type of cell found in muscle tissue.

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Na+/K+-ATPase

-ATPase (sodium-potassium adenosine triphosphatase, also known as the pump or sodium–potassium pump) is an enzyme (an electrogenic transmembrane ATPase) found in the plasma membrane of all animal cells.

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Nanometre

The nanometre (International spelling as used by the International Bureau of Weights and Measures; SI symbol: nm) or nanometer (American spelling) is a unit of length in the metric system, equal to one billionth (short scale) of a metre (m).

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Natural selection

Natural selection is the differential survival and reproduction of individuals due to differences in phenotype.

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Nernst equation

In electrochemistry, the Nernst equation is an equation that relates the reduction potential of an electrochemical reaction (half-cell or full cell reaction) to the standard electrode potential, temperature, and activities (often approximated by concentrations) of the chemical species undergoing reduction and oxidation.

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Nerve

A nerve is an enclosed, cable-like bundle of axons (nerve fibers, the long and slender projections of neurons) in the peripheral nervous system.

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Nerve agent

Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs.

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Nerve conduction velocity

Nerve conduction velocity is an important aspect of nerve conduction studies.

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Neural accommodation

Neural accommodation or neuronal accommodation occurs when a neuron or muscle cell is depolarised by slowly rising current (ramp depolarisation) in vitro.

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Neural computation

Neural computation is the hypothetical information processing performed by networks of neurons.

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Neural oscillation

Neural oscillations, or brainwaves, are rhythmic or repetitive patterns of neural activity in the central nervous system.

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Neuroanatomy

Neuroanatomy is the study of the structure and organization of the nervous system.

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Neurochip

A neurochip is a chip (integrated circuit/microprocessor) that is designed for the interaction with neuronal cells.

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Neuroglia

Neuroglia, also called glial cells or simply glia, are non-neuronal cells in the central nervous system (brain and spinal cord) and the peripheral nervous system.

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Neuromuscular junction

A neuromuscular junction (or myoneural junction) is a chemical synapse formed by the contact between a motor neuron and a muscle fiber.

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Neuron

A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.

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Neurospora crassa

Neurospora crassa is a type of red bread mold of the phylum Ascomycota.

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Neurotoxin

Neurotoxins are toxins that are poisonous or destructive to nerve tissue (causing neurotoxicity).

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin), administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the fields of life sciences and medicine.

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Node of Ranvier

Nodes of Ranvier, also known as myelin-sheath gaps, occur along a myelinated axon where the axolemma is exposed to the extracellular space.

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Noise (electronics)

In electronics, noise is an unwanted disturbance in an electrical signal.

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Olfaction

Olfaction is a chemoreception that forms the sense of smell.

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Olfactory receptor neuron

An olfactory receptor neuron (ORN), also called an olfactory sensory neuron (OSN), is a transduction cell within the olfactory system.

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Oligodendrocyte

Oligodendrocytes, or oligodendroglia,.

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Optic nerve

The optic nerve, also known as cranial nerve II, is a paired nerve that transmits visual information from the retina to the brain.

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Ordinary differential equation

In mathematics, an ordinary differential equation (ODE) is a differential equation containing one or more functions of one independent variable and its derivatives.

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Orthodromic

An orthodromic impulse runs along an axon in its anterograde direction, away from the soma.

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Osmosis

Osmosis is the spontaneous net movement of solvent molecules through a selectively permeable membrane into a region of higher solute concentration, in the direction that tends to equalize the solute concentrations on the two sides.

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Pacemaker potential

In the pacemaking cells of the heart (e.g., the sinoatrial node), the pacemaker potential (also called the pacemaker current) is the slow, positive increase in voltage across the cell's membrane (the membrane potential) that occurs between the end of one action potential and the beginning of the next action potential.

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Pancreas

The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates.

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Paralytic shellfish poisoning

Paralytic shellfish poisoning (PSP) is one of the four recognized syndromes of shellfish poisoning, which share some common features and are primarily associated with bivalve mollusks (such as mussels, clams, oysters and scallops).

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Parasympathetic nervous system

The parasympathetic nervous system (PSNS) is one of the two divisions of the autonomic nervous system (a division of the peripheral nervous system (PNS)), the other being the sympathetic nervous system.

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Partial differential equation

In mathematics, a partial differential equation (PDE) is a differential equation that contains unknown multivariable functions and their partial derivatives.

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Patch clamp

The patch clamp technique is a laboratory technique in electrophysiology used to study ionic currents in individual isolated living cells, tissue sections, or patches of cell membrane.

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Peripheral nervous system

The peripheral nervous system (PNS) is one of the two components of the nervous system, the other part is the central nervous system (CNS).

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Permeation

In physics and engineering, permeation (also called imbuing) is the penetration of a permeate (such as a liquid, gas, or vapor) through a solid.

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Permethrin

Permethrin, sold under the brand name Nix among others, is a medication and insecticide.

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Photoreceptor cell

A photoreceptor cell is a specialized type of neuroepithelial cell found in the retina that is capable of visual phototransduction.

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Phylum

In biology, a phylum (plural: phyla) is a level of classification or taxonomic rank below Kingdom and above Class.

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Physiology

Physiology is the scientific study of normal mechanisms, and their interactions, which work within a living system.

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Plant

Plants are mainly multicellular, predominantly photosynthetic eukaryotes of the kingdom Plantae.

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Plant cell

Plant cells are eukaryotic cells that differ in several key aspects from the cells of other eukaryotic organisms.

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Positive feedback

Positive feedback is a process that occurs in a feedback loop in which the effects of a small disturbance on a system include an increase in the magnitude of the perturbation.

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Potassium

Potassium is a chemical element with symbol K (from Neo-Latin kalium) and atomic number 19.

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Potassium channel

Potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms.

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Principles of Neural Science

First published in 1981 by Elsevier, Principles of Neural Science is an influential neuroscience textbook edited by Eric R. Kandel, James H. Schwartz, and Thomas M. Jessell.

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Purkinje cell

Purkinje cells, or Purkinje neurons, are a class of GABAergic neurons located in the cerebellum.

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Purkinje fibers

The Purkinje fibers (Purkinje tissue or subendocardial branches) are located in the inner ventricular walls of the heart, just beneath the endocardium in a space called the subendocardium.

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Pyramidal cell

Pyramidal cells, or (pyramidal neurons), are a type of multipolar neuron found in areas of the brain including the cerebral cortex, the hippocampus, and the amygdala.

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Quinidine

Quinidine is a pharmaceutical agent that acts as a class I antiarrhythmic agent (Ia) in the heart.

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Receptor potential

A receptor potential, also known as a generator potential, a type of graded potential, is the transmembrane potential difference produced by activation of a sensory receptor.

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Reflex

A reflex, or reflex action, is an involuntary and nearly instantaneous movement in response to a stimulus.

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Refractory period (physiology)

Refractoriness is the fundamental property of any object of autowave nature (especially excitable medium) not to respond on stimuli, if the object stays in the specific refractory state.

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Reptile

Reptiles are tetrapod animals in the class Reptilia, comprising today's turtles, crocodilians, snakes, amphisbaenians, lizards, tuatara, and their extinct relatives.

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Resting potential

The relatively static membrane potential of quiescent cells is called the resting membrane potential (or resting voltage), as opposed to the specific dynamic electrochemical phenomena called action potential and graded membrane potential.

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Retina

The retina is the innermost, light-sensitive "coat", or layer, of shell tissue of the eye of most vertebrates and some molluscs.

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Retina horizontal cell

Horizontal cells are the laterally interconnecting neurons having cell bodies in the inner nuclear layer of the retina of vertebrate eyes.

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Retinal ganglion cell

A retinal ganglion cell (RGC) is a type of neuron located near the inner surface (the ganglion cell layer) of the retina of the eye.

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Saltatory conduction

Saltatory conduction (from the Latin saltare, to hop or leap) is the propagation of action potentials along myelinated axons from one node of Ranvier to the next node, increasing the conduction velocity of action potentials.

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Santiago Ramón y Cajal

Santiago Ramón y Cajal (1 May 1852 – 17 October 1934) was a Spanish neuroscientist and pathologist, specializing in neuroanatomy, particularly the histology of the central nervous system.

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Sarcolemma

The sarcolemma (sarco (from sarx) from Greek; flesh, and lemma from Greek; sheath) also called the myolemma, is the cell membrane of a striated muscle fiber cell.

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Sarin

Sarin, or NATO designation GB (G-series, 'B'), is a highly toxic synthetic organophosphorus compound.

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Saxitoxin

Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST).

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Schwann cell

Schwann cells (named after physiologist Theodor Schwann) or neurolemmocytes are the principal glia of the peripheral nervous system (PNS).

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Sensory neuron

Sensory neurons also known as afferent neurons are neurons that convert a specific type of stimulus, via their receptors, into action potentials or graded potentials.

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Shrimp

The term shrimp is used to refer to some decapod crustaceans, although the exact animals covered can vary.

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Single-unit recording

In neuroscience, single-unit recordings provide a method of measuring the electro-physiological responses of single neurons using a microelectrode system.

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Sinoatrial node

The sinoatrial node (SA node), also known as sinus node, is a group of cells located in the wall of the right atrium of the heart.

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SK channel

SK channels (small conductance calcium-activated potassium channels) are a subfamily of Ca2+-activated K+ channels.

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Sodium

Sodium is a chemical element with symbol Na (from Latin natrium) and atomic number 11.

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Sodium channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.

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Soliton model in neuroscience

The soliton hypothesis in neuroscience is a model that claims to explain how action potentials are initiated and conducted along axons based on a thermodynamic theory of nerve pulse propagation.

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Soma (biology)

The soma (pl. somata or somas), perikaryon (pl. perikarya), neurocyton, or cell body is the bulbous, non-process portion of a neuron or other brain cell type, containing the cell nucleus.

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Somatosensory system

The somatosensory system is a part of the sensory nervous system.

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SourceForge

SourceForge is a Web-based service that offers software developers a centralized online location to control and manage free and open-source software projects.

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Speed of sound

The speed of sound is the distance travelled per unit time by a sound wave as it propagates through an elastic medium.

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Spike-timing-dependent plasticity

Spike-timing-dependent plasticity (STDP) is a biological process that adjusts the strength of connections between neurons in the brain.

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Sponge

Sponges, the members of the phylum Porifera (meaning "pore bearer"), are a basal Metazoa clade as sister of the Diploblasts.

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Squid

Squid are cephalopods of the two orders Myopsida and Oegopsida, which were formerly regarded as two suborders of the order Teuthida, however recent research shows Teuthida to be paraphyletic.

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Squid giant axon

The squid giant axon is the very large (up to 1 mm in diameter; typically around 0.5 mm) axon that controls part of the water jet propulsion system in squid.

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Summation (neurophysiology)

Summation, which includes both spatial and temporal summation, is the process that determines whether or not an action potential will be triggered by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs (temporal summation).

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Sympathetic nervous system

The sympathetic nervous system (SNS) is one of the two main divisions of the autonomic nervous system, the other being the parasympathetic nervous system.

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Synapse

In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target efferent cell.

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Synaptic potential

Synaptic potential refers to the difference in voltage between the inside and outside of a postsynaptic neuron.

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Synaptic vesicle

In a neuron, synaptic vesicles (or neurotransmitter vesicles) store various neurotransmitters that are released at the synapse.

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Tabun (nerve agent)

Tabun or GA is an extremely toxic chemical substance.

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Tactile corpuscle

Tactile corpuscles (or Meissner's corpuscles; discovered by anatomist Georg Meissner (1829–1905) and Rudolf Wagner) are a type of mechanoreceptor.

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Tetanospasmin

Tetanus toxin is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani in anaerobic conditions, causing tetanus.

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Tetanus

Tetanus, also known as lockjaw, is an infection characterized by muscle spasms.

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Tetraodontidae

The Tetraodontidae are a family of primarily marine and estuarine fish of the order Tetraodontiformes.

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Tetrodotoxin

Tetrodotoxin (TTX) is a potent neurotoxin.

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Threshold potential

In neuroscience, the threshold potential is the critical level to which a membrane potential must be depolarized to initiate an action potential.

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Time constant

In physics and engineering, the time constant, usually denoted by the Greek letter τ (tau), is the parameter characterizing the response to a step input of a first-order, linear time-invariant (LTI) system.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Translation (biology)

In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus.

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Trigger zone

In neuroscience and neurology, a trigger zone is an area of the body, or of a cell, in which a specific type of stimulation triggers a specific type of response.

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Tropomyosin

Tropomyosin is a two-stranded alpha-helical coiled coil protein found in cell cytoskeletons.

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Two-pore-domain potassium channel

The two-pore-domain potassium channel is a family of 15 members that form what is known as "leak channels" which possess Goldman-Hodgkin-Katz (open) rectification.

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University of Arizona

The University of Arizona (also referred to as U of A, UA, or Arizona) is a public research university in Tucson, Arizona.

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Ventricle (heart)

A ventricle is one of two large chambers in the heart that collect and expel blood received from an atrium towards the peripheral beds within the body and lungs.

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Verapamil

Verapamil, sold under various trade names, is a medication used for the treatment of high blood pressure, angina (chest pain from not enough blood flow to the heart), and supraventricular tachycardia.

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Vertebrate

Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones).

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Voltage

Voltage, electric potential difference, electric pressure or electric tension (formally denoted or, but more often simply as V or U, for instance in the context of Ohm's or Kirchhoff's circuit laws) is the difference in electric potential between two points.

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Voltage clamp

The voltage clamp is an experimental method used by electrophysiologists to measure the ion currents through the membranes of excitable cells, such as neurons, while holding the membrane voltage at a set level.

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Voltage-gated ion channel

Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel.

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Voltage-gated potassium channel

Voltage-gated potassium channels (VGKCs) are transmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane potential.

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Voltage-sensitive dye

Voltage-sensitive dyes, also known as potentiometric dyes, are dyes which change their spectral properties in response to voltage changes.

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Voltaic pile

The voltaic pile was the first electrical battery that could continuously provide an electric current to a circuit.

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W. A. H. Rushton

William Albert Hugh Rushton FRS (8 December 1901 – 21 June 1980) was professor of Physiology at Trinity College, Cambridge.

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Wiley-Blackwell

Wiley-Blackwell is the international scientific, technical, medical, and scholarly publishing business of John Wiley & Sons.

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Wilfrid Rall

Wilfrid Rall (August 29, 1922 - April 1, 2018) is a neuroscientist who spent most of his career at the National Institutes of Health.

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William Thomson, 1st Baron Kelvin

William Thomson, 1st Baron Kelvin, (26 June 1824 – 17 December 1907) was a Scots-Irish mathematical physicist and engineer who was born in Belfast in 1824.

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X-ray crystallography

X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.

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Xenopus

Xenopus (Gk., ξενος, xenos.

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Action Potential, Action potentials, Activation potential, Firing rate (cells), Firing rate (neurons), Nerve conduction, Nerve impulse, Nerve impulses, Nerve potential, Nerve signal, Neural firing, Neural firing rate, Neuronal firing, Spike train.

References

[1] https://en.wikipedia.org/wiki/Action_potential

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