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Neurosteroid

Index Neurosteroid

Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors. [1]

Table of Contents

  1. 148 relations: Aggression, Agonist, Alfaxalone, Alfaxolone/alfadolone, Allopregnanolone, Allosteric modulator, Analgesic, Androstadienol, Androstadienone, Androstane, Androstenol, Androstenone, Anesthetic, Anticonvulsant, Antidepressant, Anxiety, Anxiety disorder, Anxiogenic, Anxiolytic, Aphrodisiac, Étienne-Émile Baulieu, Barbiturate, Behavior, Benzodiazepine, Bile salt sulfotransferase, Biological activity, Brain injury, Catamenial epilepsy, Cell (biology), Cell surface receptor, Chemical structure, Cholestane, Cholesterol, Chronic stress, Cognitive impairment, Convulsant, Corticosterone, Dehydroepiandrosterone, Dehydroepiandrosterone sulfate, Deoxycorticosterone, Depression (mood), Disease, Endocrine gland, Endogeny (biology), Endorphins, Enzyme inducer, Epilepsy, Epipregnanolone, Essential tremor, Estradiol, ... Expand index (98 more) »

Aggression

Aggression is a behavior aimed at opposing or attacking something or someone.

See Neurosteroid and Aggression

Agonist

An agonist is a chemical that activates a receptor to produce a biological response.

See Neurosteroid and Agonist

Alfaxalone

Alfaxalone, also known as alphaxalone or alphaxolone and sold under the brand name Alfaxan, is a neuroactive steroid and general anesthetic which is used currently in veterinary practice as an induction agent for anesthesia and as an injectable anesthetic. Neurosteroid and Alfaxalone are neurosteroids.

See Neurosteroid and Alfaxalone

Alfaxolone/alfadolone

Alfaxolone/alfadolone (brand names Althesin (human), Saffan (veterinary)) is a short acting intravenous anesthetic agent. Neurosteroid and Alfaxolone/alfadolone are neurosteroids.

See Neurosteroid and Alfaxolone/alfadolone

Allopregnanolone

Allopregnanolone is a naturally occurring neurosteroid which is made in the body from the hormone progesterone. Neurosteroid and Allopregnanolone are neurosteroids.

See Neurosteroid and Allopregnanolone

Allosteric modulator

In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli.

See Neurosteroid and Allosteric modulator

Analgesic

An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.

See Neurosteroid and Analgesic

Androstadienol

Androstadienol, or androsta-5,16-dien-3β-ol, is a 16-androstene class endogenous steroid, pheromone, and chemical intermediate to several other pheromones that is found in the sweat of both men and women. Neurosteroid and Androstadienol are neurosteroids.

See Neurosteroid and Androstadienol

Androstadienone

Androstadienone, or androsta-4,16-dien-3-one, is a 16-androstene class endogenous steroid that has been described as having potent pheromone-like activities in humans. Neurosteroid and Androstadienone are neurosteroids.

See Neurosteroid and Androstadienone

Androstane

Androstane is a C19 steroidal hydrocarbon with a gonane core.

See Neurosteroid and Androstane

Androstenol

Androstenol, also known as 5α-androst-16-en-3α-ol (shortened to 3α,5α-androstenol or 3α-androstenol), is a 16-androstene class steroidal pheromone and neurosteroid in humans and other mammals, notably pigs. Neurosteroid and Androstenol are neurosteroids.

See Neurosteroid and Androstenol

Androstenone

Androstenone (5α-androst-16-en-3-one) is a 16-androstene class steroidal pheromone. Neurosteroid and Androstenone are neurosteroids.

See Neurosteroid and Androstenone

Anesthetic

An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness.

See Neurosteroid and Anesthetic

Anticonvulsant

Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

See Neurosteroid and Anticonvulsant

Antidepressant

Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction.

See Neurosteroid and Antidepressant

Anxiety

Anxiety is an emotion which is characterised by an unpleasant state of inner turmoil and includes feelings of dread over anticipated events.

See Neurosteroid and Anxiety

Anxiety disorder

Anxiety disorders are a group of mental disorders characterized by significant and uncontrollable feelings of anxiety and fear such that a person's social, occupational, and personal functions are significantly impaired.

See Neurosteroid and Anxiety disorder

Anxiogenic

An anxiogenic or panicogenic substance is one that causes anxiety.

See Neurosteroid and Anxiogenic

Anxiolytic

An anxiolytic (also antipanic or anti-anxiety agent) is a medication or other intervention that reduces anxiety.

See Neurosteroid and Anxiolytic

Aphrodisiac

An aphrodisiac is a substance alleged to increase libido, sexual desire, sexual attraction, sexual pleasure, or sexual behavior.

See Neurosteroid and Aphrodisiac

Étienne-Émile Baulieu

Étienne-Émile Baulieu (born 12 December 1926) is a French biochemist and endocrinologist who is best known for his research in the field of steroid hormones and their role in reproduction and aging.

See Neurosteroid and Étienne-Émile Baulieu

Barbiturate

Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid.

See Neurosteroid and Barbiturate

Behavior

Behavior (American English) or behaviour (British English) is the range of actions and mannerisms made by individuals, organisms, systems or artificial entities in some environment.

See Neurosteroid and Behavior

Benzodiazepine

Benzodiazepines (BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

See Neurosteroid and Benzodiazepine

Bile salt sulfotransferase

Bile salt sulfotransferase also known as hydroxysteroid sulfotransferase (HST) or sulfotransferase 2A1 (ST2A1) is an enzyme that in humans is encoded by the SULT2A1 gene.

See Neurosteroid and Bile salt sulfotransferase

Biological activity

In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.

See Neurosteroid and Biological activity

Brain injury

Brain injury (BI) is the destruction or degeneration of brain cells.

See Neurosteroid and Brain injury

Catamenial epilepsy

Catamenial epilepsy is a form of epilepsy in women where seizures are exacerbated during certain phases of the menstrual cycle.

See Neurosteroid and Catamenial epilepsy

Cell (biology)

The cell is the basic structural and functional unit of all forms of life.

See Neurosteroid and Cell (biology)

Cell surface receptor

Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the plasma membrane of cells.

See Neurosteroid and Cell surface receptor

Chemical structure

A chemical structure of a molecule is a spatial arrangement of its atoms and their chemical bonds.

See Neurosteroid and Chemical structure

Cholestane

Cholestane is a saturated tetracyclic triterpene.

See Neurosteroid and Cholestane

Cholesterol

Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Neurosteroid and Cholesterol are neurosteroids.

See Neurosteroid and Cholesterol

Chronic stress

Chronic stress is the physiological or psychological response induced by a long-term internal or external stressor.

See Neurosteroid and Chronic stress

Cognitive impairment

Cognitive impairment is an inclusive term to describe any characteristic that acts as a barrier to the cognition process or different areas of cognition.

See Neurosteroid and Cognitive impairment

Convulsant

A convulsant is a drug which induces convulsions and/or epileptic seizures, the opposite of an anticonvulsant.

See Neurosteroid and Convulsant

Corticosterone

Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroxyprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.

See Neurosteroid and Corticosterone

Dehydroepiandrosterone

Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone precursor. Neurosteroid and Dehydroepiandrosterone are neurosteroids.

See Neurosteroid and Dehydroepiandrosterone

Dehydroepiandrosterone sulfate

Dehydroepiandrosterone sulfate, abbreviated as DHEA sulfate or DHEA-S, also known as androstenolone sulfate, is an endogenous androstane steroid that is produced by the adrenal cortex. Neurosteroid and Dehydroepiandrosterone sulfate are neurosteroids.

See Neurosteroid and Dehydroepiandrosterone sulfate

Deoxycorticosterone

Deoxycorticosterone (DOC), or desoxycorticosterone, may refer to.

See Neurosteroid and Deoxycorticosterone

Depression (mood)

Depression is a mental state of low mood and aversion to activity.

See Neurosteroid and Depression (mood)

Disease

A disease is a particular abnormal condition that adversely affects the structure or function of all or part of an organism and is not immediately due to any external injury.

See Neurosteroid and Disease

Endocrine gland

Endocrine glands are ductless glands of the endocrine system that secrete their products, hormones, directly into the blood.

See Neurosteroid and Endocrine gland

Endogeny (biology)

Endogenous substances and processes are those that originate from within a living system such as an organism, tissue, or cell.

See Neurosteroid and Endogeny (biology)

Endorphins

Endorphins (contracted from endogenous morphine) are peptides produced in the brain that block the perception of pain and increase feelings of wellbeing.

See Neurosteroid and Endorphins

Enzyme inducer

An enzyme inducer is a type of drug that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme.

See Neurosteroid and Enzyme inducer

Epilepsy

Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures.

See Neurosteroid and Epilepsy

Epipregnanolone

Epipregnanolone, also known as 3β-hydroxy-5β-pregnan-20-one, 3β,5β-tetrahydroprogesterone, or 3β,5β-THP, is an endogenous neurosteroid. Neurosteroid and Epipregnanolone are neurosteroids.

See Neurosteroid and Epipregnanolone

Essential tremor

Essential tremor (ET), also called benign tremor, familial tremor, and idiopathic tremor, is a medical condition characterized by involuntary rhythmic contractions and relaxations (oscillations or twitching movements) of certain muscle groups in one or more body parts of unknown cause.

See Neurosteroid and Essential tremor

Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.

See Neurosteroid and Estradiol

Estratetraenol

Estratetraenol, also known as estra-1,3,5(10),16-tetraen-3-ol, is an endogenous steroid found in women that has been described as having pheromone-like activities in primates, including humans. Neurosteroid and Estratetraenol are neurosteroids.

See Neurosteroid and Estratetraenol

Ethanol

Ethanol (also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound with the chemical formula.

See Neurosteroid and Ethanol

Excitatory postsynaptic potential

In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential. Neurosteroid and excitatory postsynaptic potential are Neurophysiology.

See Neurosteroid and Excitatory postsynaptic potential

Fasedienol

Fasedienol (developmental code names PH94B and Aloradine), also known as 4-androstadienol or as 4,16-androstadien-3β-ol, is a pherine which is under development by VistaGen Therapeutics in a nasal spray formulation (''PRN'') for the acute treatment of social anxiety disorder.

See Neurosteroid and Fasedienol

Female

An organism's sex is female (symbol: ♀) if it produces the ovum (egg cell), the type of gamete (sex cell) that fuses with the male gamete (sperm cell) during sexual reproduction.

See Neurosteroid and Female

Fluoxetine

Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

See Neurosteroid and Fluoxetine

Fluvoxamine

Fluvoxamine, sold under the brand name Luvox among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

See Neurosteroid and Fluvoxamine

Function (biology)

In evolutionary biology, function is the reason some object or process occurred in a system that evolved through natural selection.

See Neurosteroid and Function (biology)

GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

See Neurosteroid and GABAA receptor

GABRD

Gamma-aminobutyric acid receptor subunit delta is a protein that in humans is encoded by the GABRD gene.

See Neurosteroid and GABRD

Ganaxolone

Ganaxolone, sold under the brand name Ztalmy, is a medication used to treat seizures in people with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder. Neurosteroid and Ganaxolone are neurosteroids.

See Neurosteroid and Ganaxolone

Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype.

See Neurosteroid and Gene expression

General anaesthesia

General anaesthesia (UK) or general anesthesia (US) is a method of medically inducing loss of consciousness that renders a patient unarousable even with painful stimuli.

See Neurosteroid and General anaesthesia

Homeostasis

In biology, homeostasis (British also homoeostasis) is the state of steady internal physical and chemical conditions maintained by living systems.

See Neurosteroid and Homeostasis

Hydroxydione

Hydroxydione, as hydroxydione sodium succinate (brand names Viadril, Predion, and Presuren), also known as 21-Hydroxy-5β-pregnane-3,20-dione, is a neuroactive steroid which was formerly used as a general anesthetic, but was discontinued due to incidence of thrombophlebitis in patients. Neurosteroid and hydroxydione are neurosteroids.

See Neurosteroid and Hydroxydione

Hypnotic

Hypnotic (from Greek Hypnos, sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia to produce and maintain unconsciousness, "sleep" is metaphorical as there are no regular sleep stages or cyclical natural states; patients rarely recover from anesthesia feeling refreshed and with renewed energy.

See Neurosteroid and Hypnotic

Hypothalamic–pituitary–adrenal axis

The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a pea-shaped structure located below the hypothalamus), and the adrenal (also called "suprarenal") glands (small, conical organs on top of the kidneys).

See Neurosteroid and Hypothalamic–pituitary–adrenal axis

Hypothalamus

The hypothalamus (hypothalami) is a small part of the vertebrate brain that contains a number of nuclei with a variety of functions.

See Neurosteroid and Hypothalamus

Inhibitory postsynaptic potential

An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.

See Neurosteroid and Inhibitory postsynaptic potential

Intravenous therapy

Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.

See Neurosteroid and Intravenous therapy

Irritability

Irritability is the excitatory ability that living organisms have to respond to changes in their environment. Neurosteroid and Irritability are Neurophysiology.

See Neurosteroid and Irritability

Isopregnanolone

Isopregnanolone, also known as isoallopregnanolone and epiallopregnanolone, as well as sepranolone, and as 3β-hydroxy-5α-pregnan-20-one or 3β,5α-tetrahydroprogesterone (3β,5α-THP), is an endogenous neurosteroid and a natural 3β-epimer of allopregnanolone. Neurosteroid and Isopregnanolone are neurosteroids.

See Neurosteroid and Isopregnanolone

Learning

Learning is the process of acquiring new understanding, knowledge, behaviors, skills, values, attitudes, and preferences.

See Neurosteroid and Learning

Ligand-gated ion channel

Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na+, K+, Ca2+, and/or Cl− to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.

See Neurosteroid and Ligand-gated ion channel

List of neurosteroids

This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors. Neurosteroid and list of neurosteroids are neurosteroids.

See Neurosteroid and List of neurosteroids

Luteal phase

The menstrual cycle is on average 28 days in length.

See Neurosteroid and Luteal phase

Membrane steroid receptor

Membrane steroid receptors (mSRs), also called extranuclear steroid receptors, are a class of cell surface receptors activated by endogenous steroids that mediate rapid, non-genomic signaling via modulation of intracellular signaling cascades.

See Neurosteroid and Membrane steroid receptor

Memory

Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed.

See Neurosteroid and Memory

Menopause

Menopause, also known as the climacteric, is the time when menstrual periods permanently stop, marking the end of reproduction.

See Neurosteroid and Menopause

Menstrual cycle

The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible.

See Neurosteroid and Menstrual cycle

Mental disorder

A mental disorder, also referred to as a mental illness, a mental health condition, or a psychiatric disability, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning.

See Neurosteroid and Mental disorder

Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms.

See Neurosteroid and Metabolism

Microtubule-associated protein 2

Microtubule-associated protein 2 is a protein in humans that is encoded by the MAP2 gene.

See Neurosteroid and Microtubule-associated protein 2

Minaxolone

Minaxolone (CCI-12923) is a neuroactive steroid which was developed as a general anesthetic but was withdrawn before registration due to toxicity seen with long-term administration in rats, and hence was never marketed. Neurosteroid and Minaxolone are neurosteroids.

See Neurosteroid and Minaxolone

Mirtazapine

Mirtazapine, sold under the brand name Remeron among others, is an atypical tetracyclic antidepressant, and as such is used primarily to treat depression.

See Neurosteroid and Mirtazapine

Mood disorder

A mood disorder, also known as an affective disorder, is any of a group of conditions of mental and behavioral disorder where a disturbance in the person's mood is the main underlying feature.

See Neurosteroid and Mood disorder

Nervous system

In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body.

See Neurosteroid and Nervous system

Neuromodulation

Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neurosteroid and Neuromodulation are Neurophysiology.

See Neurosteroid and Neuromodulation

Neuron

A neuron, neurone, or nerve cell is an excitable cell that fires electric signals called action potentials across a neural network in the nervous system.

See Neurosteroid and Neuron

Neuroplasticity

Neuroplasticity, also known as neural plasticity or brain plasticity, is the ability of neural networks in the brain to change through growth and reorganization. Neurosteroid and Neuroplasticity are Neurophysiology.

See Neurosteroid and Neuroplasticity

Neuroprotection

Neuroprotection refers to the relative preservation of neuronal structure and/or function.

See Neurosteroid and Neuroprotection

Neurosteroid

Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors. Neurosteroid and Neurosteroid are Neurophysiology and neurosteroids.

See Neurosteroid and Neurosteroid

Neurosteroidogenesis inhibitor

A neurosteroidogenesis inhibitor is a drug that inhibits the production of endogenous neurosteroids. Neurosteroid and neurosteroidogenesis inhibitor are neurosteroids.

See Neurosteroid and Neurosteroidogenesis inhibitor

Neurotransmission

Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short distance away. Neurosteroid and Neurotransmission are Neurophysiology.

See Neurosteroid and Neurotransmission

NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons.

See Neurosteroid and NMDA receptor

Nootropic

Nootropics (or; but not or, which are common mispronunciations), colloquially brain supplements, smart drugs and cognitive enhancers, are natural, semisynthetic or synthetic compounds which purportedly improve cognitive functions, such as executive functions, attention or memory.

See Neurosteroid and Nootropic

Paroxetine

Paroxetine, sold under the brand names Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, post-traumatic stress disorder, generalized anxiety disorder, and premenstrual dysphoric disorder.

See Neurosteroid and Paroxetine

Pharmacology

Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology.

See Neurosteroid and Pharmacology

Pherine

Pherines, also known as vomeropherines, are odorless synthetic neuroactive steroids that engage nasal chemosensory receptors and induce dose-dependent and reversible pharmacological and behavioral effects.

See Neurosteroid and Pherine

Physiology

Physiology is the scientific study of functions and mechanisms in a living system.

See Neurosteroid and Physiology

Pleasure

Pleasure is experience that feels good, that involves the enjoyment of something.

See Neurosteroid and Pleasure

Postpartum depression

Postpartum depression (PPD), also called postnatal depression, is a mood disorder experienced after childbirth, which can affect men and women.

See Neurosteroid and Postpartum depression

Postpartum psychosis

Postpartum psychosis (PPP), also known as puerperal psychosis or peripartum psychosis, involves the abrupt onset of psychotic symptoms shortly following childbirth, typically within two weeks of delivery but less than 4 weeks postpartum.

See Neurosteroid and Postpartum psychosis

Prasterone

Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for childbirth, among other uses. Neurosteroid and Prasterone are neurosteroids.

See Neurosteroid and Prasterone

Prasterone sulfate

Prasterone sulfate (brand names Astenile, Mylis, Teloin, others), also known as dehydroepiandrosterone sulfate (DHEA-S), is a naturally occurring androstane steroid which is marketed and used in Japan and other countries as a labor inducer in the treatment of insufficient cervical ripening and dilation during childbirth. Neurosteroid and Prasterone sulfate are neurosteroids.

See Neurosteroid and Prasterone sulfate

Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

See Neurosteroid and Pregnancy

Pregnane

Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone.

See Neurosteroid and Pregnane

Pregnanolone

Pregnanolone, also known as eltanolone, is an endogenous inhibitory neurosteroid which is produced in the body from progesterone. Neurosteroid and Pregnanolone are neurosteroids.

See Neurosteroid and Pregnanolone

Pregnenolone

Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. Neurosteroid and Pregnenolone are neurosteroids.

See Neurosteroid and Pregnenolone

Pregnenolone sulfate

Pregnenolone sulfate (PS, PREGS) is an endogenous excitatory neurosteroid that is synthesized from pregnenolone. Neurosteroid and pregnenolone sulfate are neurosteroids.

See Neurosteroid and Pregnenolone sulfate

Premenstrual dysphoric disorder

Premenstrual dysphoric disorder (PMDD) is a mood disorder characterized by emotional, cognitive, and physical symptoms.

See Neurosteroid and Premenstrual dysphoric disorder

Premenstrual syndrome

Premenstrual syndrome (PMS) is a disruptive set of emotional and physical symptoms that regularly occur in the one to two weeks before the start of each menstrual period.

See Neurosteroid and Premenstrual syndrome

Prodrug

A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

See Neurosteroid and Prodrug

Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Neurosteroid and Progesterone are neurosteroids.

See Neurosteroid and Progesterone

Progesterone (medication)

Progesterone (P4), sold under the brand name Prometrium among others, is a medication and naturally occurring steroid hormone. Neurosteroid and Progesterone (medication) are neurosteroids.

See Neurosteroid and Progesterone (medication)

Prosocial behavior

Prosocial behavior, or intent to benefit others, is a social behavior that "benefit other people or society as a whole", "such as helping, sharing, donating, co-operating, and volunteering".

See Neurosteroid and Prosocial behavior

Protein isoform

A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.

See Neurosteroid and Protein isoform

Psychological stress

In psychology, stress is a feeling of emotional strain and pressure.

See Neurosteroid and Psychological stress

Puberty

Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction.

See Neurosteroid and Puberty

Reuptake

Reuptake is the reabsorption of a neurotransmitter by a neurotransmitter transporter located along the plasma membrane of an axon terminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it has performed its function of transmitting a neural impulse.

See Neurosteroid and Reuptake

Sedation

Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.

See Neurosteroid and Sedation

Sedative

A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.

See Neurosteroid and Sedative

Seizure

A seizure is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

See Neurosteroid and Seizure

Seizure threshold

The term seizure threshold is used to describe the balance between excitatory (glutaminergic) and inhibitory (GABA-ergic) forces in the brain which affect how susceptible a person is to seizures.

See Neurosteroid and Seizure threshold

Selective serotonin reuptake inhibitor

Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions.

See Neurosteroid and Selective serotonin reuptake inhibitor

Serenic

A serenic, or antiaggressive agent, is a type of drug which reduces the capacity for irritability and aggression.

See Neurosteroid and Serenic

Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

See Neurosteroid and Serotonin

Sertraline

Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

See Neurosteroid and Sertraline

Sexual dimorphism

Sexual dimorphism is the condition where sexes of the same species exhibit different morphological characteristics, particularly characteristics not directly involved in reproduction.

See Neurosteroid and Sexual dimorphism

Sigma-1 receptor

The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor.

See Neurosteroid and Sigma-1 receptor

Spinal cord injury

A spinal cord injury (SCI) is damage to the spinal cord that causes temporary or permanent changes in its function.

See Neurosteroid and Spinal cord injury

SRD5A1

3-Oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene.

See Neurosteroid and SRD5A1

Status epilepticus

Status epilepticus (SE), or status seizure, is a medical condition consisting of a single seizure lasting more than 5 minutes, or 2 or more seizures within a 5-minute period without the person returning to normal between them.

See Neurosteroid and Status epilepticus

Steroid

A steroid is an organic compound with four fused rings (designated A, B, C, and D) arranged in a specific molecular configuration.

See Neurosteroid and Steroid

Steroid hormone receptor

Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells.

See Neurosteroid and Steroid hormone receptor

Testosterone

Testosterone is the primary male sex hormone and androgen in males.

See Neurosteroid and Testosterone

Testosterone (medication)

Testosterone (T) is a medication and naturally occurring steroid hormone.

See Neurosteroid and Testosterone (medication)

Tetrahydrodeoxycorticosterone

Tetrahydrodeoxycorticosterone (abbreviated as THDOC; 3α,21-dihydroxy-5α-pregnan-20-one), also referred to as allotetrahydrocorticosterone, is an endogenous neurosteroid. Neurosteroid and Tetrahydrodeoxycorticosterone are neurosteroids.

See Neurosteroid and Tetrahydrodeoxycorticosterone

Translocator protein

Translocator protein (TSPO) is an 18 kDa protein mainly found on the outer mitochondrial membrane.

See Neurosteroid and Translocator protein

Traumatic brain injury

A traumatic brain injury (TBI), also known as an intracranial injury, is an injury to the brain caused by an external force.

See Neurosteroid and Traumatic brain injury

Venlafaxine

Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class.

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Veterinary medicine

Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in non-human animals.

See Neurosteroid and Veterinary medicine

Vomeronasal receptor

Vomeronasal receptors are a class of olfactory receptors that putatively function as receptors for pheromones.

See Neurosteroid and Vomeronasal receptor

24S-Hydroxycholesterol

24S-Hydroxycholesterol (24S-HC), also known as cholest-5-ene-3,24-diol or cerebrosterol, is an endogenous oxysterol produced by neurons in the brain to maintain cholesterol homeostasis.

See Neurosteroid and 24S-Hydroxycholesterol

3α-Androstanediol

3α-Androstanediol also known as 5α-androstane-3α,17β-diol and sometimes shortened in the literature to 3α-diol, is an endogenous steroid hormone and neurosteroid and a metabolite of androgens like dihydrotestosterone (DHT). Neurosteroid and 3α-Androstanediol are neurosteroids.

See Neurosteroid and 3α-Androstanediol

3α-Hydroxysteroid dehydrogenase

3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme (1.1.1.50) that plays a role in the metabolism of steroids and non-steroidal compounds in humans and other species, such as bacteria, fungi, plants, and so on.

See Neurosteroid and 3α-Hydroxysteroid dehydrogenase

3β-Hydroxysteroid dehydrogenase

3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) is an enzyme that catalyzes the biosynthesis of the steroid progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.

See Neurosteroid and 3β-Hydroxysteroid dehydrogenase

3β-Methoxypregnenolone

3β-Methoxypregnenolone (developmental code name MAP-4343), or pregnenolone 3β-methyl ether, also known as 3β-methoxypregn-5-en-20-one, is a synthetic neuroactive steroid and derivative of pregnenolone. Neurosteroid and 3β-Methoxypregnenolone are neurosteroids.

See Neurosteroid and 3β-Methoxypregnenolone

References

[1] https://en.wikipedia.org/wiki/Neurosteroid

Also known as Neuroactive steroid, Neuroactive steroids, Neurosteroidogenesis, Neurosteroids, SBSSs, Selective brain steroidogenic stimulant, Selective brain steroidogenic stimulants.

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