10 relations: G protein–coupled receptor, Levocabastine, Meclinertant, Neuromedin N, Neurotensin, Neurotensin receptor 1, Neurotensin receptor 2, Neurotransmitter, Sortilin 1, SR-142948.
G protein–coupled receptor
G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.
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Levocabastine
Levocabastine (trade name Livostin) is a selective second-generation H1 receptor antagonists which was discovered at Janssen Pharmaceutica in 1979.
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Meclinertant
Meclinertant (SR-48692) is a drug which acts as a selective, non-peptide antagonist at the neurotensin receptor NTS1, and was the first non-peptide antagonist developed for this receptor.
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Neuromedin N
Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.
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Neurotensin
Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction with the dopaminergic system.
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Neurotensin receptor 1
Neurotensin receptor type 1 is a protein that in humans is encoded by the NTSR1 gene.
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Neurotensin receptor 2
Neurotensin receptor type 2 is a protein that in humans is encoded by the NTSR2 gene.
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Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
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Sortilin 1
Sortilin (SORT1) is a protein that in humans is encoded by the SORT1 gene on chromosome 1.
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SR-142948
SR-142948 is a drug used in scientific research which is a non-peptide antagonist selective for the neurotensin receptors, although not selective between subtypes.
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Neurotensin receptors, Receptors, neurotensin.