Nicholas Burns may refer to.
Nicholas Bernard James Adam Byrne, Jr. (born 9 October 1978) is an Irish singer-songwriter, radio and TV presenter, dancer, and former semi-professional footballer, best known for being a member of Irish music band Westlife; he was the band's oldest member.
Nicol Burne (fl. 1574–1598) was a Scottish Roman Catholic controversialist.
William Pitt Byrne (c. 1806 – 6 or 8 April 1861) was a British newspaper editor and proprietor of The Morning Post.