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Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a neurotoxic synthetic organic compound used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain. [1]

17 relations: Desipramine, Dopamine, Dopaminergic, DSP-4, Lesch–Nyhan syndrome, Monoamine transporter, MPTP, Neurotoxin, Norepinephrine, Norsalsolinol, Organic compound, Parkinson's disease, Parkinsonism, Rotenone, Substantia nigra, Superoxide, 5,7-Dihydroxytryptamine.


Desipramine (also known as desmethylimipramine) is a tricyclic antidepressant (TCA).

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Dopamine is an organic chemical of the catecholamine and phenethylamine families that plays a number of important roles in the human brain and body, as well as elsewhere in biology.

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Dopaminergic means "related to dopamine" (literally, "working on dopamine"), dopamine being a common neurotransmitter.

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For the Super NES enhancement chip see List of Super NES enhancement chips DSP-4, or N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine, is a neurotoxin selective for noradrenergic neurons, capable of crossing the blood–brain barrier.

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Lesch–Nyhan syndrome

Lesch–Nyhan syndrome (LNS), also known as Nyhan's syndrome and juvenile gout, is a rare inherited disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT), produced by mutations in the HPRT gene located on the X chromosome.

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Monoamine transporter

Monoamine transporters (MATs) are protein structures that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters.

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MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a neurotoxin precursor to MPP+, which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain.

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Neurotoxins are substances that are poisonous or destructive to nerve tissue.

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Norepinephrine, also called noradrenaline, is an organic chemical in the catecholamine family that functions in the human brain and body as a hormone and neurotransmitter.

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Norsalsolinol is a chemical compound that is produced naturally in the body through metabolism of dopamine.

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Organic compound

An organic compound is any member of a large class of gaseous, liquid, or solid chemical compounds whose molecules contain carbon.

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Parkinson's disease

Parkinson's disease (PD, also known as idiopathic or primary parkinsonism, hypokinetic rigid syndrome (HRS), or paralysis agitans) is a degenerative disorder of the central nervous system mainly affecting the motor system.

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Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia, rigidity, and postural instability.

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Rotenone is an odorless, colorless, crystalline ketonic chemical compound used as a broad-spectrum insecticide, piscicide, and pesticide.

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Substantia nigra

The substantia nigra is a brain structure located in the mesencephalon (midbrain) that plays an important role in reward, addiction, and movement.

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A superoxide, also known by the obsolete name hyperoxide, is a compound that contains the superoxide anion with the chemical formula.

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5,7-Dihydroxytryptamine (5,7-DHT) is a purported neurotoxin used in scientific research to decrease concentrations of serotonin in the brain.

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Redirects here:

6 OHDA, 6-HD, 6-Hydroxydopamine, 6-OHDA, 6-hydroxydopamine, 6-ohda, C8H11N1O3, Ohda.


[1] https://en.wikipedia.org/wiki/Oxidopamine

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