18 relations: Desipramine, Dopamine, Dopaminergic, DSP-4, FAUC50, Lesch–Nyhan syndrome, Monoamine transporter, MPTP, Neurotoxin, Norepinephrine, Norsalsolinol, Organic compound, Parkinson's disease, Parkinsonism, Rotenone, Substantia nigra, Superoxide, 5,7-Dihydroxytryptamine.
Desipramine, sold under the brand name Norpramin and Pertofrane among others, is a tricyclic antidepressant (TCA) which is used in the treatment of depression.
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
Dopaminergic means "related to dopamine" (literally, "working on dopamine"), dopamine being a common neurotransmitter.
For the Super NES enhancement chip see List of Super NES enhancement chips DSP-4, or N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine, is a neurotoxin selective for noradrenergic neurons, capable of crossing the blood–brain barrier.
FAUC50 is a template molecular skeletal super-structure that can have different joined native-head groups added to its chemical composition to make various biogenic amines, catecholamines and neurotransmitters of those aforementioned categories into covalent binding ligands.
Lesch–Nyhan syndrome (LNS), also known as juvenile gout, is a rare inherited disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT), produced by mutations in the HPRT gene located on the X chromosome.
Monoamine transporters (MATs) are protein structures that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters.
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a prodrug to the neurotoxin MPP+, which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain.
Neurotoxins are toxins that are poisonous or destructive to nerve tissue (causing neurotoxicity).
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
Norsalsolinol is a chemical compound that is produced naturally in the body through metabolism of dopamine.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.
Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia, rigidity, and postural instability.
Rotenone is an odorless, colorless, crystalline isoflavone used as a broad-spectrum insecticide, piscicide, and pesticide.
The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement.
A superoxide is a compound that contains the superoxide anion, which has the chemical formula.
5,7-Dihydroxytryptamine (5,7-DHT) is a purported neurotoxin used in scientific research to decrease concentrations of serotonin in the brain.