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P-bodies

Index P-bodies

In cellular biology, P-bodies, or processing bodies, are distinct foci formed by phase separation within the cytoplasm of a eukaryotic cell consisting of many enzymes involved in mRNA turnover. [1]

Table of Contents

  1. 30 relations: Argonaute, AU-rich element, Biotin, Biotinylation, Cell biology, Cytoplasm, Dendrite, Enzyme, Eukaryote, Flow cytometry, Invertebrate, KIAA0232, Mass spectrometry, Messenger RNA decapping, MicroRNA, Motor protein, Neuron, Nonsense-mediated decay, Phase separation, Plant, Proximity labeling, RNA-induced silencing complex, RNA-Seq, Small interfering RNA, Somatic cell, Streptavidin, Stress granule, Translation (biology), Vertebrate, Yeast.

Argonaute

The Argonaute protein family, first discovered for its evolutionarily conserved stem cell function, plays a central role in RNA silencing processes as essential components of the RNA-induced silencing complex (RISC).

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AU-rich element

Adenylate-uridylate-rich elements (AU-rich elements; AREs) are found in the 3' untranslated region (UTR) of many messenger RNAs (mRNAs) that code for proto-oncogenes, nuclear transcription factors, and cytokines.

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Biotin

Biotin (also known as vitamin B7 or vitamin H) is one of the B vitamins.

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Biotinylation

In biochemistry, biotinylation is the process of covalently attaching biotin to a protein, nucleic acid or other molecule.

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Cell biology

Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. P-bodies and cell biology are molecular biology.

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Cytoplasm

In cell biology, the cytoplasm describes all material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus.

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Dendrite

A dendrite (from Greek δένδρον déndron, "tree") or dendron is a branched protoplasmic extension of a nerve cell that propagates the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.

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Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

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Eukaryote

The eukaryotes constitute the domain of Eukarya or Eukaryota, organisms whose cells have a membrane-bound nucleus.

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Flow cytometry

Flow cytometry (FC) is a technique used to detect and measure the physical and chemical characteristics of a population of cells or particles.

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Invertebrate

Invertebrates is an umbrella term describing animals that neither develop nor retain a vertebral column (commonly known as a spine or backbone), which evolved from the notochord.

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KIAA0232

KIAA0232 is a nuclear phosphoserine protein which in humans is encoded by the KIAA0232 gene.

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Mass spectrometry

Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions.

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Messenger RNA decapping

The process of messenger RNA decapping consists of hydrolysis of the 5' cap structure on the RNA exposing a 5' monophosphate.

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MicroRNA

MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides.

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Motor protein

Motor proteins are a class of molecular motors that can move along the cytoskeleton of cells.

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Neuron

A neuron, neurone, or nerve cell is an excitable cell that fires electric signals called action potentials across a neural network in the nervous system.

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Nonsense-mediated decay

Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes.

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Phase separation

Phase separation is the creation of two distinct phases from a single homogeneous mixture.

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Plant

Plants are the eukaryotes that form the kingdom Plantae; they are predominantly photosynthetic.

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Proximity labeling

Enzyme-catalyzed proximity labeling (PL), also known as proximity-based labeling, is a laboratory technique that labels biomolecules, usually proteins or RNA, proximal to a protein of interest.

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RNA-induced silencing complex

The RNA-induced silencing complex, or RISC, is a multiprotein complex, specifically a ribonucleoprotein, which functions in gene silencing via a variety of pathways at the transcriptional and translational levels.

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RNA-Seq

RNA-Seq (named as an abbreviation of RNA sequencing) is a technique that uses next-generation sequencing to reveal the presence and quantity of RNA molecules in a biological sample, providing a snapshot of gene expression in the sample, also known as transcriptome. P-bodies and RNA-Seq are molecular biology.

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Small interfering RNA

Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA at first non-coding RNA molecules, typically 20–24 (normally 21) base pairs in length, similar to miRNA, and operating within the RNA interference (RNAi) pathway. P-bodies and Small interfering RNA are molecular biology.

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Somatic cell

In cellular biology, a somatic cell, or vegetal cell, is any biological cell forming the body of a multicellular organism other than a gamete, germ cell, gametocyte or undifferentiated stem cell.

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Streptavidin

Streptavidin is a 52 kDa protein (tetramer) purified from the bacterium Streptomyces avidinii.

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Stress granule

In cellular biology, stress granules are biomolecular condensates in the cytosol composed of proteins and RNAs that assemble into 0.1–2 μm membraneless organelles when the cell is under stress.

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Translation (biology)

In biology, translation is the process in living cells in which proteins are produced using RNA molecules as templates. P-bodies and translation (biology) are molecular biology.

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Vertebrate

Vertebrates are deuterostomal animals with bony or cartilaginous axial endoskeleton — known as the vertebral column, spine or backbone — around and along the spinal cord, including all fish, amphibians, reptiles, birds and mammals.

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Yeast

Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.

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References

[1] https://en.wikipedia.org/wiki/P-bodies

Also known as P bodies, P body, P-body, Processing bodies.