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31 relations: Activating protein 2, Adrenal ferredoxin, Adrenocorticotropic hormone, Adrenodoxin reductase, Anterior pituitary, Bond cleavage, Catalysis, Cholesterol, Cytochrome P450, DAX1, Desmolase, Electron, Enzyme, Gene, Gene expression, Hydroxylation, Inner mitochondrial membrane, Lipoid congenital adrenal hyperplasia, List of enzymes, Mitochondrion, Nuclear receptor, Peripheral membrane protein, Pregnenolone, Rate-determining step, Reducing equivalent, Side chain, Steroidogenic acute regulatory protein, Steroidogenic enzyme, Steroidogenic factor 1, Ternary complex, Transcription factor.
Activating protein 2
Activating Protein 2 (AP-2) is a family of closely related transcription factors which plays a critical role in regulating gene expression during early development.
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Adrenal ferredoxin
Adrenal ferredoxin (also adrenodoxin (ADX), adrenodoxin, mitochondrial, hepatoredoxin, ferredoxin-1 (FDX1)) is a protein that in humans is encoded by the FDX1 gene.
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Adrenocorticotropic hormone
Adrenocorticotropic hormone (ACTH, also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland.
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Adrenodoxin reductase
Adrenodoxin reductase (Enzyme Nomenclature name: adrenodoxin-NADP+ reductase, EC 1.18.1.6), was first isolated from bovine adrenal cortex where it functions as the first enzyme in the mitochondrial P450 systems that catalyze essential steps in steroid hormone biosynthesis.
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Anterior pituitary
A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis or pars anterior), is the glandular, anterior lobe that together with the posterior lobe (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis).
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Bond cleavage
Bond cleavage, or scission, is the splitting of chemical bonds.
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Catalysis
Catalysis is the increase in the rate of a chemical reaction due to the participation of an additional substance called a catalysthttp://goldbook.iupac.org/C00876.html, which is not consumed in the catalyzed reaction and can continue to act repeatedly.
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Cholesterol
Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.
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Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
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DAX1
DAX1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1) is a nuclear receptor protein that in humans is encoded by the NR0B1 gene (nuclear receptor subfamily 0, group B, member 1).
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Desmolase
A desmolase is any of various enzymes that catalyze the formation or destruction of carbon-carbon bonds within a molecule.
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Electron
The electron is a subatomic particle, symbol or, whose electric charge is negative one elementary charge.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Hydroxylation
Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound.
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Inner mitochondrial membrane
The inner mitochondrial membrane (IMM) is the mitochondrial membrane which separates the mitochondrial matrix from the intermembrane space.
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Lipoid congenital adrenal hyperplasia
Lipoid congenital adrenal hyperplasia is an endocrine disorder that is an uncommon and potentially lethal form of congenital adrenal hyperplasia (CAH).
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List of enzymes
This page lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission numbering system.
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Mitochondrion
The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.
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Nuclear receptor
In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules.
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Peripheral membrane protein
Peripheral membrane proteins are membrane proteins that adhere only temporarily to the biological membrane with which they are associated.
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Pregnenolone
Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids.
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Rate-determining step
In chemical kinetics, the overall rate of a reaction is often approximately determined by the slowest step, known as the rate-determining step (RDS) or rate-limiting step.
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Reducing equivalent
In biochemistry, the term reducing equivalent refers to any of a number of chemical species which transfer the equivalent of one electron in redox reactions.
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Side chain
In organic chemistry and biochemistry, a side chain is a chemical group that is attached to a core part of the molecule called "main chain" or backbone.
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Steroidogenic acute regulatory protein
The steroidogenic acute regulatory protein, commonly referred to as StAR (STARD1), is a transport protein that regulates cholesterol transfer within the mitochondria, which is the rate-limiting step in the production of steroid hormones.
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Steroidogenic enzyme
Steroidogenic enzymes, or steroid-metabolizing enzymes, are enzymes that are involved in steroidogenesis and steroid metabolism.
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Steroidogenic factor 1
The steroidogenic factor 1 (SF-1) protein is a transcription factor involved in sex determination by controlling activity of genes related to the reproductive glands or gonads and adrenal glands.
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Ternary complex
A ternary complex is a protein complex containing three different molecules that are bound together.
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Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
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Redirects here:
450scc, CYP11A1, CYP11A1 (gene), Cholesterol desmolase, Cholesterol monooxygenase (side-chain-cleaving), Cholesterol side-chain cleavage, Cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving), EC 1.14.15.6, P450 scc, P450scc, Side chain cleavage enzyme, Side-chain cleavage enzyme.
References
[1] https://en.wikipedia.org/wiki/Cholesterol_side-chain_cleavage_enzyme
